Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue

Neurobiology of Disease

Volumn 3, Issue 4, 1997, Pages 325-337

  Podlisny, Marcia B ^a   Citron, Martin ^a   Amarante, Patricia ^a   Sherrington, Robin ^b   Xia, Weiming ^a   Zhang, Jimin ^a   Diehl, Thekla ^a   Levesque, George ^a   Fraser, Paul ^b   Haass, Christian ^c   Koo, Edward H M ^a   Seubert, Peter ^d   St George Hyslop, Peter ^b   Teplow, David B ^a   Selkoe, Dennis J ^a  

^a Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^d Athena Neurosciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0030889220     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1006/nbdi.1997.0129     Document Type: Article

References (26)

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