Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation

Journal of Biological Chemistry

Volumn 273, Issue 48, 1999, Pages 32322-32331

  Steiner, Harald ^a   Capell, Anja ^a   Pesold, Brigitte ^a   Citron, Martin ^b   Kloetzel, Peter M ^c   Selkoel, Dennis J ^d   Romig, Helmut ^e   Mendla, Klaus ^e   Haass, Christian ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^b AMGEN INC   (United States)

^c HUMBOLDT UNIVERSITY   (Germany)

^d HARVARD MEDICAL SCHOOL   (United States)

^e BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CASPASE; PRESENILIN 1; PROTEASOME; PROTEIN PRECURSOR;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; KIDNEY CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN STABILITY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; CELL LINE; CYSTEINE ENDOPEPTIDASES; DIMERIZATION; GENE EXPRESSION REGULATION; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; PEPTIDE FRAGMENTS; PRESENILIN-1; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; TRANSFECTION;

EID: 0033610863     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.48.32322     Document Type: Article

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