-
1
-
-
0031918785
-
The genetics of Alzheimer's disease: Current status and future prospects
-
Blacker, D. & Tanzi, R.E. The genetics of Alzheimer's disease: current status and future prospects. Arch. Neurol. 55, 294-296 (1998).
-
(1998)
Arch. Neurol.
, vol.55
, pp. 294-296
-
-
Blacker, D.1
Tanzi, R.E.2
-
2
-
-
0027407565
-
Apolipoprotein E: High avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter, W.J. et al. Apolipoprotein E: High avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl Acad. Sci. USA 90, 1977-1981 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
-
3
-
-
17744410836
-
APOE-4 and age-at-onset of Alzheimer's disease: The NIMH genetics initiative
-
Blacker, D. et al. APOE-4 and age-at-onset of Alzheimer's disease: the NIMH Genetics Initiative. Neurology 48, 139-147 (1997).
-
(1997)
Neurology
, vol.48
, pp. 139-147
-
-
Blacker, D.1
-
4
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between Apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and alzheimer disease meta analysis consortium
-
Farrer, L.A. et al. Effects of age, sex, and ethnicity on the association between Apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. J.A.M.A. 278, 1349-1356 (1997).
-
(1997)
J.A.M.A.
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
-
5
-
-
0030752288
-
Genetic association of the low density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease
-
Kang, D.E. et al. Genetic association of the low density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease. Neurology 49, 56-61 (1997).
-
(1997)
Neurology
, vol.49
, pp. 56-61
-
-
Kang, D.E.1
-
6
-
-
0029128232
-
LDL-receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation
-
Kounnas, M. et al. LDL-receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation. Cell 82, 331-340 (1995).
-
(1995)
Cell
, vol.82
, pp. 331-340
-
-
Kounnas, M.1
-
7
-
-
0027076834
-
Alpha-2-macroglobulin, a multi-functional binding protein with targeting characteristics
-
Borth, W. Alpha-2-macroglobulin, a multi-functional binding protein with targeting characteristics. F.A.S.E.B. J. 6, 3345-3353 (1992).
-
(1992)
F.A.S.E.B. J.
, vol.6
, pp. 3345-3353
-
-
Borth, W.1
-
8
-
-
0025080835
-
Sequence identity between the alpha-2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor
-
Strickland, D.K. et al. Sequence identity between the alpha-2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor. J. Biol. Chem. 265, 17401-17404 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 17401-17404
-
-
Strickland, D.K.1
-
9
-
-
0028180385
-
Expression of alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells
-
Lopes, M.B., Bogaev, C.A., Gonias, S.L. & Vandenberg, S.R. Expression of alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells. F.E.B.S. Lett. 338, 301-305 (1993).
-
(1993)
F.E.B.S. Lett.
, vol.338
, pp. 301-305
-
-
Lopes, M.B.1
Bogaev, C.A.2
Gonias, S.L.3
Vandenberg, S.R.4
-
11
-
-
0030610309
-
Alpha-2-macroglobulin as a beta-amyloid peptide-binding plasma protease
-
Du, Y. et al. Alpha-2-macroglobulin as a beta-amyloid peptide-binding plasma protease. J. Neurochem. 63, 299-305 (1997).
-
(1997)
J. Neurochem.
, vol.63
, pp. 299-305
-
-
Du, Y.1
-
12
-
-
0032539723
-
Alpha-2-macroglobulin associates with β-amyloid peptide and prevents fibril formation
-
Hughes, S.R. et al. Alpha-2-macroglobulin associates with β-amyloid peptide and prevents fibril formation. Proc. Natl Acad. Sci. USA 95, 3275-3280 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 3275-3280
-
-
Hughes, S.R.1
-
13
-
-
0031594756
-
Alpha-2-macroglobulin attenuates beta-amyloid peptide 1-40 fibril formation and associated neurotoxicity of cultured fetal rat cortical neurons
-
Du, Y. et al. Alpha-2-macroglobulin attenuates beta-amyloid peptide 1-40 fibril formation and associated neurotoxicity of cultured fetal rat cortical neurons. J. Neurochem. 70, 1182-1188 (1998).
-
(1998)
J. Neurochem.
, vol.70
, pp. 1182-1188
-
-
Du, Y.1
-
14
-
-
0013642132
-
Degradation of amyloid beta protein by a serine proteinase alpha-2-macroglobulin complex
-
Qiu, W.Q. et al. Degradation of amyloid beta protein by a serine proteinase alpha-2-macroglobulin complex. J. Biol. Chem. 271, 8443-8451 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8443-8451
-
-
Qiu, W.Q.1
-
15
-
-
0030611584
-
Alpha-2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein
-
Narita, M., Holtzman, D.M., Schwartz, A.L. & Bu, G. Alpha-2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein. J. Neurochem. 69, 1904-1911 (1997).
-
(1997)
J. Neurochem.
, vol.69
, pp. 1904-1911
-
-
Narita, M.1
Holtzman, D.M.2
Schwartz, A.L.3
Bu, G.4
-
16
-
-
0030770726
-
Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12
-
Pericak-Vance, M.A. et al. Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. J.A.M.A. 278, 1237-1241 (1997).
-
(1997)
J.A.M.A.
, vol.278
, pp. 1237-1241
-
-
Pericak-Vance, M.A.1
-
17
-
-
0025899129
-
A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene
-
Matthijs, G. & Marynen, P. A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene. Nuceic Acids Res. 19, 5102 (1991).
-
(1991)
Nuceic Acids Res.
, vol.19
, pp. 5102
-
-
Matthijs, G.1
Marynen, P.2
-
18
-
-
0031912715
-
A sibship test for linkage in the presence of association: The Sib Transmission/Disequilibrium
-
Spielman, R.S. & Ewens, W.J. A sibship test for linkage in the presence of association: The Sib Transmission/Disequilibrium. Am. J. Hum. Genet. 62, 450-458 (1998).
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 450-458
-
-
Spielman, R.S.1
Ewens, W.J.2
-
19
-
-
0029653616
-
A second-generation YACcontig map of human chromosome 12
-
Krauter, K. et al. A second-generation YACcontig map of human chromosome 12. Nature 377, 321-333 (1995).
-
(1995)
Nature
, vol.377
, pp. 321-333
-
-
Krauter, K.1
-
20
-
-
0032547332
-
Genetic studies on chromosome 12 in late onset Alzheimer's disease
-
in press
-
Wu, W.S. et al. Genetic studies on chromosome 12 in late onset Alzheimer's disease. J.A.M.A. in press (1998).
-
(1998)
J.A.M.A.
-
-
Wu, W.S.1
-
21
-
-
0031820439
-
APOE polymorphism predicts when-not whether-individuals are predisposed to develop Alzheimer's disease
-
Meyer, M.R. et al. APOE polymorphism predicts when-not whether-individuals are predisposed to develop Alzheimer's disease. Nature Genet. 19, 321-322 (1998).
-
(1998)
Nature Genet.
, vol.19
, pp. 321-322
-
-
Meyer, M.R.1
-
22
-
-
17344374322
-
A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia
-
Bullido, M.J. et al. A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia. Nature Genet. 18, 69-71 (1998).
-
(1998)
Nature Genet.
, vol.18
, pp. 69-71
-
-
Bullido, M.J.1
-
23
-
-
0031911596
-
A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease
-
Lambert, J-C. et al. A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease. Hum. Mol. Genet. 7, 533-540 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 533-540
-
-
Lambert, J.-C.1
-
24
-
-
0030723043
-
Distortion of allelic expression of apotipoprotein E in Alzheimer's disease
-
Lambert, J-C. et al. Distortion of allelic expression of apotipoprotein E in Alzheimer's disease. Hum. Mol. Genet 6, 2151-2154 (1997).
-
(1997)
Hum. Mol. Genet
, vol.6
, pp. 2151-2154
-
-
Lambert, J.-C.1
-
25
-
-
0031278270
-
Lack of apolipoprotein E dramatically reduces amyloid betapeptide deposition
-
Bales, K.R. et al. Lack of apolipoprotein E dramatically reduces amyloid betapeptide deposition. Nature Genet. 17, 263-264 (1997).
-
(1997)
Nature Genet.
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
-
26
-
-
0000140969
-
Inhibition of alpha-2-macroglobulin/proteinase-mediated degradation of amyloid beta peptide by apolipoprotein E and atpha-1-antichymotrypsin
-
Zhang, Z. et al. Inhibition of alpha-2-macroglobulin/proteinase-mediated degradation of amyloid beta peptide by apolipoprotein E and atpha-1-antichymotrypsin. Int. J. Exp. Clin. Invest. 3, 156-161 (1996).
-
(1996)
Int. J. Exp. Clin. Invest.
, vol.3
, pp. 156-161
-
-
Zhang, Z.1
-
27
-
-
17344369955
-
Confirmation of an association between a polymorphism in exon 3 of LRP and Alzheimer's disease
-
in press
-
Hollenbach, E., Ackermann, S., Hyman, B.T. & Rebeck, G.W. Confirmation of an association between a polymorphism in exon 3 of LRP and Alzheimer's disease. Neurology, in press.
-
Neurology
-
-
Hollenbach, E.1
Ackermann, S.2
Hyman, B.T.3
Rebeck, G.W.4
-
28
-
-
0027961102
-
Reliability and validity of NINCDS-ADRDA criteria for Alzheimer's disease
-
Blacker, D. et al. Reliability and validity of NINCDS-ADRDA criteria for Alzheimer's disease. Arch. Neurol. 51, 1198-1204 (1994).
-
(1994)
Arch. Neurol.
, vol.51
, pp. 1198-1204
-
-
Blacker, D.1
-
29
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease
-
McKhann, G. et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34, 939-944 (1984).
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
-
30
-
-
0025262212
-
Transmission and age-at-onset patterns in familial Alzheimer's disease: Evidence for heterogeneity
-
Farrer, L.A. et al. Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for heterogeneity. Neurologyt 40, 395-403 (1990).
-
(1990)
Neurologyt
, vol.40
, pp. 395-403
-
-
Farrer, L.A.1
-
31
-
-
0028305380
-
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
-
Corder, E.H. et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nature Genet. 7, 180-184 (1994).
-
(1994)
Nature Genet.
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
-
33
-
-
0029886532
-
Parametric and nonparametric linkage analysis: A unified multipoint approach
-
Kruglyak, L., Daly, M.J., Reeve-Daly, M.P. & Lander, E.S. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am. J. Hum. Genet. 58, 1347-1363 (1996).
-
(1996)
Am. J. Hum. Genet.
, vol.58
, pp. 1347-1363
-
-
Kruglyak, L.1
Daly, M.J.2
Reeve-Daly, M.P.3
Lander, E.S.4
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