Mutagenesis identifies new signals for β-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Aβ42

Journal of Biological Chemistry

Volumn 274, Issue 27, 1999, Pages 18851-18856

  Perez, Ruth G ^a,b   Soriano, Salvador ^c   Hayes, Jay D ^a   Ostaszewski, Beth ^d   Xia, Weiming ^d   Selkoe, Dennis J ^d   Chen, Xiaohua ^c   Stokin, Gorazd B ^c   Koo, Edward H ^c  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b University of California San Diego ^*  (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; TYROSINE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; ENDOCYTOSIS; GENE EXPRESSION; INTERNALIZATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TURNOVER TIME;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CHO CELLS; CRICETINAE; ENDOCYTOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033516554     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.27.18851     Document Type: Article

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