Biomarkers in disease and health

British Journal of Nutrition

Volumn 86, Issue SUPPL. 1, 2001, Pages

  Branca, F ^a   Hanley, A B ^b,e,f   Pool Zobel, B ^c   Verhagen, H ^d  

^a ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

^b CENTRAL SCIENCE LABORATORY   (United Kingdom)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d TNO   (Netherlands)

^e LEATHERHEAD FOOD RESEARCH   (United Kingdom)

^f UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

Biomarkers; Breast cancer; Colorectal cancer; Coronary heart disease; Health and disease; Osteoporosis; Stomach cancer

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; FAT; FOLIC ACID; INDICATOR; LIPID; SEX HORMONE; TRACE ELEMENT;

BODY MASS; BREAST CANCER; CALCIUM INTAKE; CANCER; COLORECTAL CANCER; DIET; DIET THERAPY; ENVIRONMENTAL FACTOR; FOOD; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; HEALTH; HORMONE METABOLISM; HUMAN; ISCHEMIC HEART DISEASE; MEASUREMENT; NONHUMAN; NUTRIENT; OSTEOPOROSIS; OUTCOMES RESEARCH; PHYSICAL DISEASE; PREDICTION; REVIEW; RISK MANAGEMENT; SERUM; STOMACH CANCER; TARGET ORGAN;

EID: 0034809262     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/bjn2001339     Document Type: Review

References (401)

1. Effect of selenium supplementation on plasma lipid and lipoprotein cholesterol levels in adult rats
2. Phytoestrogens: Epidemiology and a possible role in cancer protection
3. Dietary phytoestrogens and cancer: In vivo and in vivo studies
4. Sensory acceptance of Japanese green tea and soy products is linked to genetic sensitivity to 6-n-propylthiouracil
5. Isolation of exfoliated colonic epithelial cells. A novel non-invasive approach to the study of cellular markers
6. Somatic cell mutations in cancer epidemiology
7. Effects of dietary wheat bran fiber on rectal epithelial cell proliferation in patients with resection for colorectal cancers
8. The effect of wheat bran fiber and calcium supplementation on rectal mucosal proliferation rates in patients with resected adenomatous colorectal polyps
9. Randomized, double-blinded, placebo-controlled study of effect of wheat bran fiber and calcium on fecal bile acids in patients with resected adenomatous colon polyps
10. Multifactorial therapeutic approach to secondary prevention in coronary heart disease: Preliminary report after 3-year follow-up
11. Risk for osteoporosis in black women
12. Chromosome aberrations, mitogen-induced blastogenesis and proliferative rate index in peripheral lymphocytes from 106 control individuals of the UK population
13. Dietary fibre, complex carbohydrate and coronary artery disease
14. Change and secular trends in physical activity patterns in young adults: A seven year longitudinal follow up in the Coronary Artery Risk Development in Young Adults Study (CARDIA)
15. K-ras mutations are found in DNA extracted from the plasma of patients with colorectal cancer
16. Detection of DNA-reactive metabolites in serum and their tissue distribution in mice exposed to multiple doses of carcinogen mixtures: Role in human biomonitoring
17. Differential expression of estrogen receptors alpha and beta mRNA during differentiation of human osteoblast SV-HFO cells
18. Comparison of techniques for monitoring human exposure to genotoxic chemicals
19. Meat and colorectal cancer - The unanswered questions and the commitment of the Meat and Livestock Commission to finding the answers through strategic research
20. A population-based dietary inventory of cooked meat and assessment of the daily intake of food mutagens
21. Genetic epidemiology of dyslipidaemia and atherosclerosis
22. Low-density lipoprotein (LDL) particle size and plasma triglyceride (TG) as predictors of coronary heart disease (CHD) in older Japanese American men
23. Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women
24. The anti-carcinogenic plant compound indole-3-carbinol differentially modulates P450-mediated steroid hydroxylase activities in mice
25. Homocysteine: Update on a new risk factor
26. Inhibitin of endothelial cell adhesion molecule expression by high density lipoproteins
27. Effects of fish oil fecal bacterial enzymes and steroid excretion in healthy volunteers: Implications for colon cancer prevention
28. Missing anti-proliferative effect of fish oil on rectal epithelium in healthy volunteers consuming a high-fat diet: Potential role of the n-3:n-6 fatty acid ratio
29. Does yogurt enriched with Bifidobacterium longum affect colonic microbiology and fecal metabolites in healthy subjects
30. Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenis: Effect of butyrate, desoxycholate, calcium, ammonia, and pH
31. N-nitroso compounds and human cancer: Where do we stand?
32. The role of individual susceptibility in cancer burden related to environmental exposure
33. Ki-ras mutation modifies the protective effect of dietary monounsaturated fat and calcium on sporadic colorectal cancer
34. 32P-postlabeling assay
35. Biomarkers as predictive tools in toxicity testing
36. Atherosclerosis: A nutritional disease of childhood
37. Folic acid supplementation and cell kinetics of rectal mucosa in patients with ulcerative colitis
38. Epidemiology and mechanisms relating diet to risk of colorectal cancer
39. The potential role of endogenously formed N-nitroso compounds in colorectal cancer
40. Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer?
41. Resistant starch lowers fecal concentrations of ammonia and phenols in humans
42. Fruit vegetables, and cancer prevention: A review of the epidemiological evidence
43. Insulin resistance - Current concepts
44. Consumption of Brussels sprouts results in elevated alpha-class glutathione S-transferase in human blood
45. Can clonidine, enoximone, and enalaprilat help to protect the myocardium against ischaemia in cardiac surgery
46. The Scottish heart health study dietary intake by food frequency questionnaire and odds ratios for coronary heart disease risk 1. The Macronutrients
47. Calcium, phosphorus, vitamin D, dairy products and colorectal carcinogenesis: A French case-control study
48. Thiamin status, diuretic medications, and the management of congestive heart failure
49. Fecal bile acid excretion pattern in colonic cancer patients
50. The platelet-vascular component of the hemostatic system in residents of the far North
51. N-acetyl-transferase polymorphisms and colorectal cancer: A HuGE review
52. Dietary folate from vegetables and citrus fruit decreases plasma homocysteine concentrations in humans in a dietary controlled trial
53. Low-dose folic acid supplementation decreases plasmahomocysteine concentrations - A randomized trial
54. Hypercholesterolemia in the United States: How far have we come?
55. Frequency and spectrum of c-Ki-ras mutations in human sporadic colon carcinomas arising in ulcerative colitis and pancreatic adenocarcinoma
56. Molecular approach in cancer epidemiology: Early detection of carcinogens mutations in a whole genome (Review)
57. Raised affinity for extracellular sodium of the sodium-lithium countertransporter is associated with a family history of hypertension and uraemia in patients with renal disease
58. Biological effect of isoflavones present in soy in premenopausal women: Implications for the prevention of breast cancer
59. Biological effects of isoflavones in young women - Importance of the chemical composition of soya products
60. Isoflavones, lignans and stilbenes - Origins, metabolism and potential importance to human health
61. Randomized, double-blinded placebo-controlled intervention study with supplemental calcium in families with hereditary nonpolyposis colorectal cancer
62. Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: The Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993
63. A pathological study of sudden coronary death in China Report of 89 Autopsy Cases
64. Glutathione S-transferase M1 and T1 polymorphisms: Susceptibility to colon cancer and age of onset
65. Gluthathione S-transferase u genotype, diet, and smoking as determinants of fister chromid exchange frequency in lymphocytes
66. Obesity: Genes, glands or gluttony
67. Biochemical marker of bone metabolism: An overview
68. Ambulatory systolic blood pressure is related to the deletion allele of the angiotensin I converting enzyme gene in young normotensives with parental history of hypertension
69. Adults aged 20 and older should have their cholesterol measured
70. Femoral strength is better predicted by finite element models models than QCT and DXA
71. Atheroma of the aortic arch and embolic risk
72. Human somatic mutation assays as biomarkers of carcinogenesis
73. Positive association between self-reported fatty food consumption and factor VII coagulant activity a risk factor for coronary heart disease in 4246 middle-aged mean
74. Flavonoids - Chemistry, metabolism, cardioprotective effects, and dietary sources
75. Apoptosis: Molecular control point in toxicity
76. A mathematical model for the determination of the optimum value of the treatment threshold for a continuous risk factor
77. Digestion and physiological properties of resistant starch in the human large bowel
78. Relating genotype and phenotype in breast cancer: An analysis of the prognostic significance of amplification at eight different genes or loci and of p53 mutations
79. Body fat, coronary heart disease, and stroke in Japanese men
80. Risk factors for bone loss in healthy postmenopausal women
81. Calcium retention and hormone levels in black and white women on high- and low-calcium diets
82. Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: Studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancers
83. DNA adducts and chronic degenerative disease. Pathogenetic relevance and implications in preventive medicine
84. Early on set of gastric carcinoma and constitutional deletion of 18p
85. Lower androgenicity is associated with higher plasma levels of prothrombotic factors irrespective of age, obesity, body fat distribution, and related metabolic parameters in men
86. Genetic metabolic polymorphisms and the risk of cancer: A review of the literature
87. Meat intake, heterocyclic amines, and risk of breast cancer: A case-control study in Uruguay
88. Dietary fatty acids and the regulation of plasma low density lipoprotein cholesterol concentrations
89. Effects of a low-fat diet on levels of oxidative damage to DNA in human peripheral nucleated blood cells
90. The lessons of life: Keynote address to the Nutrition and Cancer Conference
91. Nature and nurture: Possibilities for cancer control
92. The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today
93. Different morphometric and densitometric parameters predict cervical and trochanteric hip fracture: The EPIDOS Study
94. Susceptibility to ulcerative colitis and Crohn's disease: Interactions between glutathione S-transferase GSTM1 and GSTT1 genotypes
95. Folate deficiencies and cardiovascular pathologies
96. Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes
97. Current diet does not relate to bone mineral density after the menopause
98. Copper supplementation and the maintenance of bone mineral density in middle-aged women
99. Phytoestrogens and the menopause
100. Strategies for cardiovascular disease prevention: Importance of public and community health programs
101. Relationship between insulin resistance and coronary heart disease in diabetes mellitus and the general population: A critical appraisal
102. Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors
103. A diet rich in fat and poor in dietary fiber increases the in vitro formation of reactive oxygen species in human feces
104. Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease
105. Blood pressure and blood lipid levels among vegetarian, semi-vegetarian, and non-vegetarian native Africans
106. Radioimmunoassay for plasma glutathione S-transferase-pi and its clinical application in gastrointestinal cancer
107. Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers
108. Determination of DNA adducts of malonaldehyde in humans: Effects of dietary fatty acid composition
109. Moderately high consumption of ethanol suppresses bone resorption in ovariectomized but not in sexually intact adult female rats
110. Intervention trials on colorectal cancer prevention
111. Human cancer syndromes: Clues to the origin and nature of cancer
112. A genetic model for colorectal tumorigenesis
113. Androgen and vitamin D receptor gene polymorphisms: The long and short of prostate cancer risk
114. A comparison of lymphocyte micronuclei and plasma micronutrients in vegetarians and non-vegetarians
115. Moderate wine consumption protects against hydrogen peroxide-induced DNA damage
116. Vitamin-E supplements and their effect on vitamin-E status in blood and genetic damage rate in peripheral blood lymphocytes
117. The genus Allium
118. Vitamin K intake and hip fractures in women: A prospective study
119. Body weight and coronary heart disease mortality an analysis in relation to age and smoking habit 15 years follow-up data from the Whitehall study
120. A prospective study of coronary heart disease in relation to fasting insulin, glucose, and diabetes. The Atherosclerosis Risk in Communities (ARIC) Study
121. Effect of β-carotene supplementation on indices of colonic cell proliferation
122. Serum lipids and incidence of coronary heart disease: Findings from the Systolic Hypertension in the Elderly Program (SHEP)
123. Gender differences in cardiovascular risk factors in obese, nondiabetic first degree relatives of African Americans with type 2 diabetes mellitus
124. Relations of body fat and fat distribution to the serum lipid, apolipoprotein and insulin concentrations of Samoan men and women
125. Gene-environment interactions in the application of biomarkers of susceptibility in epidemiology
126. Association of lipoprotein (a) levels and apolipoprotein (a) phenotypes with coronary heart disease in patients with essential hypertension
127. Fiber and breast cancer: Another piece of the puzzle - But still an incomplete picture
128. Influence of dietary protein supplements on the formation of bacterial metabolites in the colon
129. Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics
130. Shift from a dairy product-rich to a dairy product-free diet: Influence on cytotoxicity and genotoxicity of fecal water - Potential risk factors for colon cancer
131. The effect of milk and lactobacillus feeding on human intestinal bacterial enzymes activity
132. The metabolism of heterocyclic amines
133. Diet and its relation to coronary heart disease and death in three populations
134. Lipid-regulating and antiatherosclerotic therapy: Current options and future approaches
135. Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project
136. Variability in systolic blood pressure. A risk factor for coronary heart disease?
137. Dietary calcium, saturated fat, fiber and vitamin C as predictors of forearm cortical and trabecular bone mineral density in healthy children and adolescents
138. Polymorphisms of the genes encoding apoproteins A-I, B, C-III and E and LDL receptor, and cholesterol and LDL metabolism during increased cholesterol intake. Common alleles of the apoprotein E gene show the greatest regulatory impact
139. Butyrate acts as a survival factor for colonic epithelial cells: Further fuel for the in vivo versus in vitro debate
140. Vitamin E prevents exercise-induced DNA damage
141. New methods for detection of low levels of DNA damage in human populations
142. Suppressing effect of Lactobacillus casei administration on the urinary mutagenicity arising from ingestion of fried ground beef in the human
143. Mutagenicity of human urine cause by ingestion of fried ground beef
144. Diet, nutrition and cancer
145. Fibrinogen and factor VII in the prediction of coronary risk: Results from the PROCAM study in healthy men
146. Antioxidant vitamin-cardiovascular disease hypothesis is still promising, but still unproven: The need for randomised trials
147. Protein phosphatase 1 and 2A inhibitors activate acylCoA: Cholesterol transferase and cholesterol ester formation in isolated rat hepatocytes
148. Oxidative DNA damage in humans - Comparison between high and low habitual fruit and vegetables consumption
149. Fruit and vegetable consumption and cancer risk
150. Comparison of blood lipid and lipoprotein values in young adults who die suddenly and unexpectedly from atherosclerotic coronary artery disease with other noncardiac deaths
151. Coronary atherosclerosis in relation to body fatness and its distribution
152. Calcium intake: Covariates and confounders
153. An 18-year prospective study of dietary calcium and bone mineral density in the hip
154. Vitamin D and bone health
155. An analysis of randomized trials evaluating the effect of cholesterol reduction on total mortality and coronary heart disease incidence
156. Role of the cardiac renin-angiotensin system in hypertensive heart disease
157. High acetaldehyde levels in saliva ater ethanol conuption: Methodological aspects and pathogenetic implications
158. Recent advances in chemoprevention of cancer
159. Concentrations of Lp (a) in black and white young adults: Relations to risk factors for cardiovascular disease
160. Is there any difference in coronary heart disease risk factors and prevalence of fatty liver in subjects with normal body mass index having different physiques?
161. Hypomethylation as a cause of homocysteine-induced cell damage in human cell lines
162. Phytoestrogens and human health effect: Weighing up the current evidence
163. Circulating adhesion molecules VCAM-1, ICAM-1, and E-selection in carotid atherosclerosis and incident coronary heart diseases cases: The Atherosclerosis Risk in Communities (ARIC) Study
164. IARC publication no 150
165. Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor
166. Association of serum vitamin levels, LDL susceptibility to oxidation and autoantibodies against MDA-LDL with carotid atherosclerosis: A case-control study
167. Effect of increased physical activity on bone mineral density in postmenopausal osteoporotic women
168. Homocysteine and vitamins in cardiovascular disease
169. Species specificity of monoclonal antibodies to human tartrate-resistant acid phosphatase
170. Dietary fiber and plant foods in relation to colorectal cancer mortality: The Seven Countries Study
171. Relationship between trace element content and mechanical bone strength
172. The effect of a shift from a mixed diet to a lacto-vegetarian diet on human urinary and fecal mutagenic activity
173. The potential role of iron in colorectal cancer
174. Low serum cholesterol increases in the risk of noncardiovascular events: An antagonist viewpoint
175. Variables of the fibrinolytic system: Risk indicators for CHD
176. Coagulation factor VII and the risk of coronary heart disease in healthy men
177. Urinary estrogen metabolites and breast cancer: A case-controls study
178. Effect of dietary broccoli on human in vivo drug metabolizing enzymes: Evaluation of caffeine, oestrone and chlorzoxazone metabolism
179. Regional obesity and risk of cardiovascular disease in the Framingham Study
180. Cholesterol and atherosclerosis: A contemporary perspective
181. Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma
182. Role of calcium and vitamin D in the prevention and the treatment of postmenopausal osteoporosis: An overview
183. Short stature and heart disease: Nature or nurture? The EARS Group
184. Aerobic exercise and bone density at the hip in postmenopausal women: A meta-analysis
185. The variable metabolic response to dietary isoflavones in humans
186. Use of carcinongen-DNA and carcinogen-protein adduct biomarkers for cohort selection and as modifiable end points in chemoprevention trials
187. Arteriosclerotic heart disease in a favoured community
188. Nutrition chemoprevention of gastrointestinal cancers: A critical review
189. Accuracy of screening for gastric cancer using serum pepsinogen concentrations
190. Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: A follow-up study
191. Controversies surrounding diet and breast cancer
192. Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells
193. Blood coagulation system as a component for hereditary predisposition to coronary heart disease
194. Platelet aggregation in healthy persons and patients with coronary heart disease during exercise and at rest
195. Bone mineral density and biochemical markers of bone turnover in healthy elderly men and women
196. Alcohol, fish, fibre and antioxidant vitamins intake do not explain population differences in coronary heart disease mortality
197. Impact of body mass index on coronary heart disease risk factors in men and women: The Framingham Offspring Study
198. Supplementation of MCF-7 cells with essential fatty acids induces the activation of protein kinase C in response to IGF-1
199. Left ventricular hypertrophy and cardiovascular prognosis
200. Dyslipidemia and hyperglycemia predict coronary heart disease events in middle-aged patients with NIDDM
201. Cardiovascular risk factors clustering with endogenous hyperinsulinaemia predict death from coronary heart disease in patients with Type II diabetes
202. Dietary vitamin C and bone mineral density in postmenopausal women in Washington State, USA
203. Cancer mortality in Europe
204. Food groups and colorectal cancer risk
205. Evaluation of newer prognostic markers for adult soft tissue sarcomas
206. Prevalence of coronary heart disease indicated by electrocardiogram abnormalities and risk factors in developing countries
207. Impact of Lactobacillus acidophilus on the normal intestinal flora after administration of two antibiotic agents
208. Effect of Lactobacillus acidophilus supplements on mutagen excretion faeces and urine in humans
209. Dual role of oestrogens as hormones and procarcinogens: Tumour initiation by metabolic activation of oestrogens
210. Glutathione transferase (GSTM1) null genotype, smoking and prevalence of colorectal adenomas
211. Lactobacillus strain Gg supplementation decreases colonic hydrolytic and reductive enzyme activities in healthy female adults
212. Biomarkers of increased susceptibility to gastrointestinal cancer
213. Inherited and acquired risk factors in colonic neoplasia and modulation by chemopreventive intervention
214. Biomarkers as intermediate end points in chemoprevention trials
215. Microsatellite instability: Marker of mutator phenotype in cancer
216. Quantitation of DNA from exfoliated colonocytes isolated from human stool surface as a novel noninvasive screening test for colorectal cancer
217. Intake of carrots, spinach and supplements containing vitamin A in relation to risk of breast cancer
218. Identification of differentially expressed genes after phytoestrogen exposure
219. The effect of feeding Brassica vegetables and intact glucosinolates on Mixed Function Oxidase activity in the liver and intestines of rats
220. Protein degration by human intestinal bacteria
221. Butyrate production from dietary fibre and protection against bowel cancer in a rat model
222. Breast cancer: Molecular epidemiology
223. A randomized trial of a low fat high fibre diet in the recurrence of colorectal polyps
224. Blood pressure, stroke, and coronary heart disease. Part 1, prolonged differences in blood pressure: Prospective observational studies corrected for the regression dilution bias
225. Cholesterol intake and plasma cholesterol: An update
226. Bacterial enzymes: Their role in the formation of mutagens and carcinogens in the intestine
227. Cellular and molecular mechanisms of osteoporosis
228. The risk factor profile of rectosigmoid adenomas: A prospective screening study of 665 patients in a clinical rehabilitation centre
229. Microsatellite alterations as clonal markers for the detection of human cancer
230. DNA damage in breast epithelial cells: Detection by the single-cell (comet) assay and induction by human mammary lipid extracts
231. Dietary xylitol protects against weakening of bone biomechanical properties in ovariectomized rats
232. Women and heart disease
233. Genetic determination of coagulation factor VIIc levels among healthy middle-aged women
234. Smoking, antioxidant vitamins, and the risk of hip fracture
235. Effects of age, physical training, and physical fitness on coronary heart disease risk factors in older track athletes at twenty-year follow-up
236. Diet and hip fracture risk: A case-control study. Study Group of the Multiple Risk Survey on Swedish Women for Eating Assessment
237. Dietary fatty acids and blood coagulation
238. Risk of coronary heart disease and activation of factor XII in middle-aged men
239. Roles of seafood and magnesium intake on prevention of cardiovascular disease: Findings from the International Nutritional Epidemiological Study
240. Coagulation factor VII mass and activity in young men with myocardial infarction at a young age: Role of plasma lipoproteins and factor VII genotype
241. Bone density and the bone metabolism are normal after long-term gluten-free diet in young celiac patients
242. Reversal of low bone density with a gluten-free diet in children and adolescents with celiac disease
243. Suppressive effect of feeding yogurt or lactose on N-methyl-N′-nitrosoguanidine-induced gastric tumorigenesis in rats
244. Scanning the genome for essential hypertension loci
245. Measurement and metabolism of isoflavonoids and lignans in the human male
246. Antioxidant nutrient supplementation reduces the susceptibility of low density lipoprotein to oxidation in patients with coronary artery disease
247. Is Helicobacter pylori a cause of gastric cancer? An appraisal of the seroepidemiological evidence
248. Food consumption patterns of adults in the United Arab Emirates
249. Prevalence of risk factors for cardiovascular disorders among men and women in an Arab Gulf community
250. Etheno DNA-base adducts from endogenous reactive species
251. High dietary ù-6 polyunsaturated fatty acids drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects
252. Detection of pre operative serum anti-p53 antibodies in gastric cancer
253. Elevated estrogen 16α-hydroxylase activity: Is this a genotoxic or nongenotoxic biomarker in human breast cancer risk
254. Vegetable and fruit consumption and cancer risk
255. Laboratory probing of oncogens from human liquid and solid specimens as markers of exposure to toxicants
256. Plasma malondialdehyde as biomarker for oxidative stress: Reference interval and effects of life-style factors
257. Effect of consumption of Brussels sprouts on plasma and urinary glutathione S-transferase class-α and -β in humans
258. Biochemical variables in pre and post menopausal women: Reconciling the calcium and estrogen hypothesis
259. Association of estrogen receptor beta gene polymorphism with bone mineral density
260. Gamma, but not alpha, tocopherol levels in serum are reduced in coronary heart disease patients
261. Fractional esterification rate of cholesterol in high density lipoprotein (HDL) can predict the particle size of low density lipoprotein and HDL in patients with coronary heart disease
262. Changes in total serum cholesterol and other risk factors for cardiovascular disease in Japan, 1980-1989
263. Mutagen hypersensitivity as a biomarker of genetic predisposition to carcinogenesis
264. Antioxidant status and lipid peroxidation after short term maximal exercise in trained and untrained humans
265. Lipoprotein (a) as a determinant of coronary heart disease in young women
266. Estrogen regulation of gene expression in osteoblasts and osteoclasts
267. A high performance liquid chromatography system for quantification of hydroxyl radical formation by determination of dihydroxy benzoic acids
268. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against against coronary heart disease
269. Differential ligand activation of estrogen receptors ERL and Erâ at AP1 sites
270. Differential immunohistochemical detection of transforming growth factor alpha, amphiregulin and CRIPTO in human normal and malignant breast tissues
271. Nonlipoprotein risk factors for coronary heart disease: Evaluation and management
272. Colorectal cancer: Controversial role of meat consumption
273. Mapping a gene involved in regulating cholesterol absorption. The cholesterolemia locus os found at chromosome 2p21
274. Better discrimination of hip fracture using bone density, geometry and architecture
275. Feeding of a well-cooked beef diet containing a high heterocyclic amine content enhances colon and stomach carcinogenesis in 1,2-dimethylhydrazine-treated rats
276. Molecular epidemiology: Insights into cancer susceptibility, risk assessment, and prevention
277. Biomarkers and molecular epidemiology in mutation/cancer research
278. The relationship between trabecular bone strength and bone mineral density assessed by dual photon and dual energy X-ray absorptiometry in the proximal tibia
279. Determination of steady-state levels of oxidative DNA base modifications in mammalian cells by means of repair endonucleases
280. Coeliac disease and bone mineral density in adult female patients
281. Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells
282. Endogenous DNA damage and oxidised DNA bases in human colon cells from biopsies and HT29 cells
283. Consumption of vegetables reduces genetic damage in humans: First results of an intervention trial with carotenoid-rich foods
284. Mechanisms by which vegetable consumption reduces genetic damage in humans
285. Induction of DNA damage in human colon cells derived from biopsies by suggested risk factors of colon cancer
286. Detection of genotoxic effects in human gastric and nasal mucosa cells isolated from biopsy samples
287. Overview of the biologic markers of breast cancer
288. Vegetables, fruit and phytoestrogens as preventive agents
289. K-ras mutations in putative preneoplastic lesions in human colon
290. Naturally occurring oestrogens in foods - A review
291. Cholesterol screening and family history of vascular disease
292. The pathogenesis of age-related osteoporotic fracture: Effects of dietary calcium deprivation
293. Prevention of postmenopausal osteoporosis. A comparative study of exercise, calcium supplementation, and hormone-replacement therapy
294. Collagen: Molecules biology, diseases, and potentials for therapy
295. Associations between physical activity and risk factors for coronary heart disease: The Cardiovascular Risk in Young Finns Study
296. Effects of a traditional lifestyle on obesity in Pima Indians
297. Coronary heart disease risk factors in relation to the menopause
298. Nutritional factors and colon cancer
299. 3H]thymidine
300. Does calcium supplementation prevent postmenopausal bone loss? A double-blind, controlled clinical study
301. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women
302. Comprehensive mutational scanning of the p53 coding region by two-dimensional gene scanning
303. Bone mass homeostasis and bisphosphonate action
304. The missing bone
305. Ras gene alterations in human lung cancer
306. Relationship between adiposity and food intake: An example of pseudo-contradictory results obtained in case-control versus between populations studies
307. Effects of dietary fatty acids on breast and prostate cancers: Evidence from in vitro experiments and animal studies
308. Immunochemical techniques in biological monitoring
309. Biomarkers of dietary fat composition in young adults with a parental history of premature coronary heart disease compared with controls. The EARS study
310. Diet, gut microflora and carcinogenesis
311. Endogenous N-nitrosation in man assessed by measurement of apparent total N-nitroso compounds in feces
312. Genetic predisposition to hyperhomocysteinemia: Deficiency of methylenetetrahydrofolate reductase (MTHFR)
313. Magnesium deficiency induces bone loss in the rat
314. Resistive training maintains bone material density in postmenopausal women
315. Formation of F-2-isoprostanes in oxidized low density lipoprotein: Inhibitory effects of hydroxytyrosol
316. The role of trace minerals in osteoporosis
317. Minor dietary factors in relation to coronary heart disease: Flavonoids, isoflavones and boron
318. Moderate alcohol consumption does not augment bone density in ovariectomized rats
319. Epithelial ovarian cancer: Influence of polymorphism at the glutathione
320. DXA-derived section modules and bone mineral content predict long-bone torsional strength
321. Functional food science and substrate metabolism
322. Lipid peroxyl radicals from oxidized oils and heme-iron: Implication of a high-fat diet in colon carcinogenesis
323. Population correlates of coagulation factor VII: Importance of age, sex, and menopausal status as determinants of activated factor VII
324. Factors associated with low and elevated plasma high density lipoprotein cholesterol and apolipoprotein A-I levels in the Framingham Offspring Study
325. DNA adducts in humans as dosimeters of exposure to environmental, occupational, or dietary genotoxins
326. Exposure of infants to phyto-oestrogens from soy-based infant formula
327. Screening of potential chemopreventive agents using biochemical markers of carcinogenesis
328. Differential expression of the mitochondrial gene cytochrome oxidase II in benign and malignant breast tissue
329. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumours
330. Genetic variationa and nutrition
331. Macro and trace mineral metabolism in coronary heart disease
332. Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans
333. Association of 1-hydroxypyrene-glucuronide in human urine with cigarette smoking and broiled or roasted meat consumption
334. CYP1A1 genetic polymorphisms and in situ colorectal cancer
335. Dietary antioxidants and plasma lipids: The Cardia Study
336. Pentadecanoic acid in serum as a marker for intake of milk fat
337. Metabolic polymorphisms and cancer susceptibility
338. The role of cardiac troponin T and other new biochemical markers in evaluation and risk stratification of patients with acture chest pain syndromes
339. Familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC): A review of clinical, genetic and therapeutic aspects
340. Lifetime milk consumption and bone mineral density in older women
341. Identification of a class 3 aldehyde dehydrogenase in human saliva and increased levels of this enzyme, glutathione S-transferase, and DT-diaphorase in the saliva of subjects who continually ingest large quantities of coffee or broccoli
342. Relation between alcohol intake, lipoproteins and coronary heart disease: The interest continues
343. Epidemiologic evidence for vitamin E in prevention of cardiovascular disease
344. Vegetables, fruit, and cancer. I. Epidemiology
345. Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: Relationship to cytochrome p4501A2 and N-acetyl-transferase activity
346. Calcium homeostasis and human evolution
347. Nutrition and breast cancer risk: Can an effect via insulin resistance be demonstrated
348. Breast cancer and the western diet: Role of fatty acids and antioxidant vitamins
349. Effect of red and white wine on serum lipids, platelet aggregation, oxidation products and antioxidants: A preliminary report
350. Plasma Lp (a) and t-PA-PAI-1 complex levels in coronary heart disease
351. Dietary xylitol retards bone resorption in rats
352. Glutathione S-transferase activity and glutathione S-transferase activity and glutathione S-transferase μ expression in subjects with risk for colorectal cancer
353. Mineral content in bones of chicken with symptomless celiac disease and gluten-free diet
354. Effects of indole-3-carbinol on the metabolism of 4-(methylnitrosamino)-1(3-pyridyl)-1-butanone in smokers
355. Relation of lipoprotein A to coronary heart disease and duplex sonographic findings of the carotid arteries in heterozygous familial hypercholesterolemia
356. Adipose tissue fatty acids in Scottish men and women
357. Prevalence of coronary heart disease and associated risk factors among elderly Finnish men in the Seven Countries study
358. Risk of fracture in elderly patients: A new predictive index based on bone mineral density and finite element analysis
359. Cardiovascular health and trans fatty acid consumption
360. Cytogenetic end-points as biological dosimeter and predictors of risk in epidemiological studies
361. Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women
362. Estrogen has rapid tissue-specific effects on rat bone
363. In vivo toxicity, pharmacokinetics, and anticancer activity of genistein linked to recombinant human epidermal growth factor
364. Detection of c-Ki-ras mutation by PCR/RFLP analysis and diagnosis of pancreatic adenocarcinomas
365. Sixteen-year coronary mortality in black and white men with diabetes screened for the Multiple Risk Factor Intervention Trial (MRFIT)
366. Bone mineral density in coeliac disease
367. Lipoprotein oxidation, antioxidants and cardiovascular risk: Epidemiologic evidence
368. The role of biotransformation in dietary (anti) carcinogenesis
369. Effect of resistant starch on colonic fermentation, bile acid metabolism, and mucosal proliferation
370. Dietary pectin influences fibrin network structure in hypercholesterolaemic subjects
371. Identification of authentic estrogen receptor in cultured endothelial cells: A potential mechanism for steroid hormone regulation of endothelial function
372. Genotoxic activity in human faecal water and the role of bile acids: A study using the alkaline comet assay
373. Reduction of oxidative DNA-damage in humans by Brussels sprouts
374. Cancer prevention by dietary contituents in toxicological perspective
375. Ethnic immunity to coronary heart disease
376. Serum total cholesterol and long-term coronary heart disease mortality in different cultures: Twenty-five year follow-up of the Seven Countries Study
377. Divergent incorporation of dietary trans fatty acids in different serum lipid fractions
378. Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool
379. Differences in the p53 gene mutational spectra of prostate cancers between Japan and western countries
380. Potential mechanisms of metabolic imprinting that lead to chronic disease
381. Active serum vitamin D levels are inversely correlated with coronary calcification
382. Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St Thomas' Atherosclerosis Regression Study
383. DNA mismatch repair genes and their association with colorectal cancer
384. A comparison of the effects of dietary cellulose and fermentable galacto oligosaccharide, in a rat model of colorectal carcinogenesis: Fermentab confers greater protection than non-fermentable fibre in both high and backgrounds
385. Carcinogen-DNA and carcinogen-protein adducts in molecular epidemiology
386. Carotid atherosclerosis in men with low levels of HDL cholesterol
387. Novel serum markers of bone resorption: Clinical assessment and comparison with established urinary indices
388. Hemostatic tests in the prediction of atherothrombotic disease
389. Geographic association between urinary excretion of N-nitroso compounds and oesophageal cancer mortality in China
390. Breast cancer: Weighing the evidence for a promotion role of dietary fat
391. Prolonged administration of beta-alanyl-L-histidinato zinc prevents bone loss in ovariectomized rats
392. Blood and urine levels of tea catechins after ingestion of different amounts of green tea by volunteers
393. Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1-treated rat liver and human oral mucosal cells
394. The relationship of nutritional copper to the development of postmenopausal osteoporosis in rats
395. Dietary flavonoid intake and the risk of cardiovascular disease
396. Gene expression profiles in normal and cancer cells
397. Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer
398. The level of plasma lipoprotein (a) and its correlation with other lipids in patients with hypertension and CHD