Ambulatory systolic blood pressure is related to the deletion allele of the angiotensin I converting enzyme gene in young normotensives with parental history of hypertension

Clinical and Experimental Hypertension

Volumn 20, Issue 3, 1998, Pages 283-294

  Chrostowska, Marzena ^a   Narkiewicz, Krzysztof ^a,c   Bigda, Justyna ^a   Winnicki, Mikolaj ^a   Pawlowski, Ryszard ^a   Rossi, Gian Paolo ^b   Krupa Wojciechowska, Barbara ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b UNIVERSITY OF PADOVA   (Italy)

^c Division of Cardiovascular Diseases   (United States)

Author keywords

Ambulatory blood pressure; Angiotensin converting enzyme; Blood pressure; Family history; Genes; Genetics; Polymorphism

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DNA;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FAMILY HISTORY; GENE; HEART RATE; HUMAN; HUMAN EXPERIMENT; HYPERTENSION; MALE; PARENT; POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE;

EID: 0031948797     PISSN: 10641963     EISSN: None     Source Type: Journal    
DOI: 10.3109/10641969809052122     Document Type: Article

References (34)

1. Hunt, S.C., Hasstedt, S.J., Kuida, H., Stults, B.M., Hopkins, P.N., Williams, R.R. Genetic heritability and common environmental components of resting and stressed blood pressures, lipids, and body mass index in Utah pedigrees and twins. Am J Epidemiol 1989; 129: 625-638
2. Havlik, R.J., Garrison, R.J., Feinleib, M., Kannel, W.B., Castelli, W.P., McNamara, P.M. Blood pressure aggregation in families. Am J Epidemiol 1979; 110: 304-312.
3. Ward, R., Familial aggregation and genetic epidemiology of blood pressure. In: Hypertension: pathophysiology, diagnosis, and management. Laragh, J.H., Brenner, B.M., Raven Press, New York, 1995, 67-88.
4. Cambien, F., Poirier, O., Lecerf, L., Evans, A., Cambou, J.P., Arveiler, D., Luc, G., Bard, J.M , Bara, L., Ricard, S., Tiret, L., Amouyel, P., Alhenc-Gelas, F., Soubrier, F. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-643.
5. Mattu, R.K., Needham, E W.A., Galton, D.J., Frangos, E., Clark, A.J.L., Caulfield, M. A DNA variant at the angiotensin-converting enzyme gene locus associates with coronary artery disease in the Caerphilly Heart study. Circulation 1995; 91: 270-274.
6. Lindpaintner, K., Pfeffer, M.A., Kreutz, R., Stampfer, M.J., Grodstein, F., LaMotte, F., Buring, J., Hennekens, C.H. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med 1995; 332: 706-711
7. Ludwig, E., Corneli, P.S., Anderson, J.L., Marshall, H.W., Lalouel, J.M., Ward, R.H. Angiotensin-converting enzyme gene is associated with myocardial infarction but not with development of coronary stenosis. Circulation 1995; 91: 2120-2124.
8. Badenhop, R.F., Wang, X.L , Wilcken, D.E.L. Angiotensin-converting enzyme genotype in children and coronary events in their grandparents. Circulation 1995; 91: 1655-1658.
9. Samani, N.J., Thompson, J.R., O'Toole, L., Channer, K., Woods, K.L. A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction. Circulation 1996; 94: 708-712.
10. Lindpaintner, K , Lee, M., Larson, M.G., Rao, V.S., Pfeffer, M.A., Ordovas, J.M., Schaefer, E.J., Wilson, A.F., Wilson, P.W.F., Vasan, R.S., Myers, R.H., Levy, D. Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med 1996; 334: 1023-1028.
11. Gharavi, A.G., Lipkowitz, M.S., Diamond, J.A., Jhang, J.S., Phillips, R.A. Deletion polymorphism of the angiotensin-converting enzyme gene is independently associated with left ventricular mass and geometric remodeling in systemic hypertension. Am J Cardiol 1996; 77: 1315-1319
12. Hingorani, A.D., Jia, H , Stevens, P.A., Hopper, R., Dickerson, J.E.C., Brown, M.J. Renin-angiotensin gene polymorphism influence blood pressure and the response to angiotensin converting enzyme inhibition. J Hypertens 1995; 13: 1602-1609.
13. Cambien, F., Alhenc-Gelas, F., Herbeth, B., Andre, J.L., Rakotovao, R., Gonzales, M.F., Allegrini, J., Bloch, C. Familial resemblance of plasma angiotensin-converting enzyme level the Nancy Study Am J Hum Genet 1988; 43: 774-780.
14. Rigat, B., Hubert, C., Alhenc-Gelas, F., Cambien, F., Corvol, P., Soubrier, F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990; 86: 1434-1346
15. Villard, E., Tiret, L., Visvikis, S., Rakotovao, R., Cambien, F., Soubrier, F. Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis. Am J Hum Genet 1996; 58: 1268-1278.
16. Cesari, M , Narkiewicz, K., Bigda, J., Chrostowska, M., Szczech, R., Pawlowski, R., Rossi, G.P The Deletion/Insertion ACE gene polymorphism affects plasma levels of ACE to a similar extent in monozygotic and dizygotic normotensive twins. Hypertension 1996; 28: 36 (abstract).
17. Ueda, S., Elliott, H.L., Morton, J.J., Connell, J.M. Enhanced pressor response to angiotensin I in normotensive men with the deletion genotype (DD) for angiotensin-converting enzyme. Hypertension 1995; 25: 1266-1269.
18. Berge, K.E., Berg, K. No effect of insertion/deletion polymorphism at the ACE locus on normal blood pressure level or variability. Clin Genet 1994; 45: 169-174.
19. Harrap, S.B., Davidson, H.R., Connor, J.M., Soubrier, F., Corvol, P., Fraser, R., Foy, C.J.W The angiotensin I converting enzyme gene and predisposition to high blood pressure Hypertension 1993; 21. 455-460.
20. Jeunemaitre, X., Lifton, R.P., Hunt, S.C , Williams, R.R., Lalouel, J.M Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension. Natur Genet 1992; 1 72-75.
21. Lachurie, M.L., Azizi, M., Guyene, M.D., Aihenc-Gelas, F., Menard, J. Angiotensin-converting enzyme gene polymorphism has no influence on the circulating renin-angiotensin-aldosterone system or blood pressure in normotensive subjects. Circulation 1995; 91: 2933-2942.
22. Schmidt, S., van Hooft, I.M.S., Grobbee, D.E., Ganten, D., Ritz, E. Polymorphism of the angiotensin I converting enzyme gene is apparently not related to high blood pressure: Dutch Hypertension and Offspring Study J Hypertens 1993; 11: 345-348.
23. Pickering, T.G., O'Brien, E. Second international consensus meeting on twenty-four-hour ambulatory blood pressure measurement: consensus and conclusions. J Hypertens 1991; 9 (Suppl. 8): S2-S6
24. Pawlowski, R., Welz, A., Burkiewicz, A. Comparison of yield and quality of DNA isolated from human blood using three different methods. Ann Acad Med Gedan 1994; 24: 23-29.
25. Rigat, B., Hubert, C., Corvol, P , Soubrier, F PCR detection of the insertion/deletion polymorphism of the human angiotensin I-converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1) Nucl Acids Res 1992; 20: 1433.
26. Shanmungam, V , Sell, K.W., Saha, B K. Mistyping ACE heterozygotes. PCR Methods Appl 1993; 3: 120-121
27. Fogarty, D.G., Maxwell, A P , Doherty, C C., Hughes, A E , Nevin, N.C.: ACE gene typing. Lancet 1994, 343, 851.
28. O'Brien, E., Mee, F., Atkins, N., O'Malley, K. Accuracy of the Spacelabs 90207 determined by the British Hypertension Society protocol J Hypertens 1991; 9:573-574.
29. Herrera, V.L.M., Ruiz-Opazo, N. Beyond genetic markers: hypertension genes. J Hypertens 1994; 12. 847-856.
30. Allemann, Y., Weidmann, P. Cardiovascular, metabolic and hormonal dysregulations in normotensive offspring of essential hypertensive parents. J Hypertens 1995; 13: 163-173.
31. Ravogli, A , Trazzi, S., Vittani, A , Villani, A., Mutti, E , Cuspidi, C., Sampieri, L., De Ambroggi, L., Parati, G., Zanchetti, A , Mancia, G Early 24 hour blood pressure elevation in normotensive subjects with parental hypertension. Hypertension 1990; 16: 491-497
32. van Hooft, I.M.S., Grobbee, D.E., Waal-Manning, H.J., Hofman, A. Twenty-four-hour ambulatory blood pressure pattern in youngsters with a different family history of hypertension: The Dutch Hypertension and Offspring Study J Hypertens 1989, 7(suppl 6):S66-S67.
33. Widgren, B.R., Herlitz, H., Jonsson, O., Berglund, G., Wikstrand, J , Andersson, O.K. Normotensive young men with family histories of hypertension gain weight and decrease their intraerythrocyte sodium content during a 5-year follow-up. J Intern Med 1991; 229: 217-223.
34. van Hooft, I.M.S., Grobbee, D E., Derkx, F.H.M., de Leeuw, P.W., Schalekamp M.A.D.H., Hofman, A. Renal hemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with hypertensive and normotensive parents. N Engl J Med 1991; 324: 1305-1311.