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Volumn 4, Issue 5, 1998, Pages 1125-1134

In vivo toxicity, pharmacokinetics, and anticancer activity of Genistein linked to recombinant human epidermal growth factor

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GENISTEIN; GRANULOCYTE COLONY STIMULATING FACTOR; METHOTREXATE; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT EPIDERMAL GROWTH FACTOR;

EID: 14444272510     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (71)

References (41)
  • 1
    • 0028152943 scopus 로고
    • Progress from clinical trials on breast cancer
    • Phila.
    • Wood, W. C. Progress from clinical trials on breast cancer. Cancer (Phila.), 74: 2606-2609, 1994.
    • (1994) Cancer , vol.74 , pp. 2606-2609
    • Wood, W.C.1
  • 2
    • 0028813358 scopus 로고
    • Sequential or alternating doxorubicin and CMF regimens in breast cancer with more than three positive nodes: Ten-year results
    • Bonadonna, G., Zambetti, M., and Valagussa, P. Sequential or alternating doxorubicin and CMF regimens in breast cancer with more than three positive nodes: ten-year results. J. Am. Med. Assoc., 273: 542-547, 1995.
    • (1995) J. Am. Med. Assoc. , vol.273 , pp. 542-547
    • Bonadonna, G.1    Zambetti, M.2    Valagussa, P.3
  • 3
    • 0028350749 scopus 로고
    • Randomized trial of cyclophosphamide, methotrexate, and 5-fluorouracil with or without estrogenic recruitment in women with metastatic breast cancer
    • Phila.
    • Ingle, J. N., Foley, J. F., Mailliard, J. A., Krook, J. E., Hartmann, L. C., Jung, S. H., Veeder, M. H., Gesme, D. H., Jr., Hatfield, A. K., and Goldberg, R. M. Randomized trial of cyclophosphamide, methotrexate, and 5-fluorouracil with or without estrogenic recruitment in women with metastatic breast cancer. Cancer (Phila.), 73: 2337-2343, 1994.
    • (1994) Cancer , vol.73 , pp. 2337-2343
    • Ingle, J.N.1    Foley, J.F.2    Mailliard, J.A.3    Krook, J.E.4    Hartmann, L.C.5    Jung, S.H.6    Veeder, M.H.7    Gesme Jr., D.H.8    Hatfield, A.K.9    Goldberg, R.M.10
  • 4
    • 0028269421 scopus 로고
    • High-dose doxorubicin, etoposide, and cyclophosphamide with stem cell reinfusion in patients with metastatic or high-risk primary breast cancer
    • Phila.
    • Somlo, G., Doroshow, J. H., Forman, S. H., Leong, L. A., Margolin, K. A., Morgan, R. J., Jr., Raschoko, J. W., Akkman, S. A., Ahn, C., and Nagasawa, S. High-dose doxorubicin, etoposide, and cyclophosphamide with stem cell reinfusion in patients with metastatic or high-risk primary breast cancer. Cancer (Phila.), 73: 1678-1685, 1994.
    • (1994) Cancer , vol.73 , pp. 1678-1685
    • Somlo, G.1    Doroshow, J.H.2    Forman, S.H.3    Leong, L.A.4    Margolin, K.A.5    Morgan Jr., R.J.6    Raschoko, J.W.7    Akkman, S.A.8    Ahn, C.9    Nagasawa, S.10
  • 5
    • 0027989598 scopus 로고
    • New chemotherapeutic agents for breast cancer
    • Phila.
    • Abrams, J. S., Moore, T. D., and Friedman, M. New chemotherapeutic agents for breast cancer. Cancer (Phila.), 84: 1164-1176, 1994.
    • (1994) Cancer , vol.84 , pp. 1164-1176
    • Abrams, J.S.1    Moore, T.D.2    Friedman, M.3
  • 6
    • 0025321157 scopus 로고
    • Epidermal growth factor
    • Carpenter, G., and Cohen, S. Epidermal growth factor. J. Biol. Chem., 265: 7709-7712, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 7709-7712
    • Carpenter, G.1    Cohen, S.2
  • 9
    • 0002350734 scopus 로고
    • Antibodies to growth factors and receptors
    • V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.) Philadelphia, PA: J. B. Lippincott Company
    • Mendelsohn, J., and Baselga, J. Antibodies to growth factors and receptors. In: V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.) Biologic Therapy of Cancer: Principles and Practice, pp. 607-623. Philadelphia, PA: J. B. Lippincott Company, 1995.
    • (1995) Biologic Therapy of Cancer: Principles and Practice , pp. 607-623
    • Mendelsohn, J.1    Baselga, J.2
  • 10
    • 0025874765 scopus 로고
    • Epidermal growth factor receptor expression as a prognostic indicator in breast cancer
    • Toi, M., Osaki, A., Yamada, H., and Toge, T. Epidermal growth factor receptor expression as a prognostic indicator in breast cancer. Eur. J. Cancer, 27: 977-980, 1991.
    • (1991) Eur. J. Cancer , vol.27 , pp. 977-980
    • Toi, M.1    Osaki, A.2    Yamada, H.3    Toge, T.4
  • 11
    • 0028266876 scopus 로고
    • EGF receptor expression, regulation, and function in breast cancer
    • Chrysogelos, S. A, and Dickson, R. B. EGF receptor expression, regulation, and function in breast cancer. Breast Cancer Res. Treat., 29: 29-40, 1994.
    • (1994) Breast Cancer Res. Treat. , vol.29 , pp. 29-40
    • Chrysogelos, S.A.1    Dickson, R.B.2
  • 12
    • 0028330743 scopus 로고
    • The epidermal growth factor receptor as a prognostic marker: Results of 370 patients and review of 3009 patients
    • Flx, S. B. The epidermal growth factor receptor as a prognostic marker: results of 370 patients and review of 3009 patients. Breast Cancer Res. Treat., 29: 41-49, 1994.
    • (1994) Breast Cancer Res. Treat. , vol.29 , pp. 41-49
    • Flx, S.B.1
  • 13
    • 0029021518 scopus 로고
    • Heterodimerization and functional interaction between EGF receptor family members: A new signaling paradigm with implications for breast cancer research
    • Earp, H. S., Dawson, T. L., Li, X., and Yu, H. Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research. Breast Cancer Res. Treat., 35: 115-132, 1995.
    • (1995) Breast Cancer Res. Treat. , vol.35 , pp. 115-132
    • Earp, H.S.1    Dawson, T.L.2    Li, X.3    Yu, H.4
  • 14
    • 0029067672 scopus 로고
    • An incomplete program of cellular tyrosine phosphorylations by kinase-defective epidermal growth factor receptors
    • Wright, J. D., Reuter, C. W., and Weber, M. J. An incomplete program of cellular tyrosine phosphorylations by kinase-defective epidermal growth factor receptors. J. Biol. Chem., 270: 12085-12093, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12085-12093
    • Wright, J.D.1    Reuter, C.W.2    Weber, M.J.3
  • 15
    • 0029904262 scopus 로고    scopus 로고
    • Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling
    • Broome, M. A., and Hunter, T. Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling. J. Biol. Chem., 271: 16798-16806, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16798-16806
    • Broome, M.A.1    Hunter, T.2
  • 16
    • 0028047315 scopus 로고
    • Mammary tumors expressing the neu protooncogene possess elevated cSrc tyrosine kinase activity
    • Muthuswamy, S. K. Mammary tumors expressing the neu protooncogene possess elevated cSrc tyrosine kinase activity. Mol. Cell. Biol., 14: 735-743, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 735-743
    • Muthuswamy, S.K.1
  • 17
    • 0026674221 scopus 로고
    • Characterization of protein tyrosine kinases from human breast cancer: Involvement of the cSrc oncogene product
    • Ottenhoff-Kalff, A. K., Rijksen, G., van Beurden, E. A., Hennipman, A., Michels, A. A., and Staal, G. E. Characterization of protein tyrosine kinases from human breast cancer: involvement of the cSrc oncogene product. Cancer Res., 52: 4773-4778, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 4773-4778
    • Ottenhoff-Kalff, A.K.1    Rijksen, G.2    Van Beurden, E.A.3    Hennipman, A.4    Michels, A.A.5    Staal, G.E.6
  • 21
    • 0022576064 scopus 로고
    • Use of a novel colony assay to evaluate the cytotoxicity of an immunotoxin containing pokeweed antiviral protein against blast progenitor cells freshly obtained from patients with common B-lineage acute lymphoblastic leukemia
    • Uckun, F. M., Kazimiera, J. G-P., Kersey, J. H., Houston, L., and Vallera, D. A. Use of a novel colony assay to evaluate the cytotoxicity of an immunotoxin containing pokeweed antiviral protein against blast progenitor cells freshly obtained from patients with common B-lineage acute lymphoblastic leukemia. J. Exp. Med., 163: 347-368, 1986.
    • (1986) J. Exp. Med. , vol.163 , pp. 347-368
    • Uckun, F.M.1    Kazimiera, J.G.-P.2    Kersey, J.H.3    Houston, L.4    Vallera, D.A.5
  • 22
    • 0020963903 scopus 로고
    • Physiologically based pharmacokinetic modelling: Principles and applications
    • Gerlowski, L. E., and Jain, R. K. Physiologically based pharmacokinetic modelling: principles and applications. J. Pharm. Sci., 72: 1103-1126, 1983.
    • (1983) J. Pharm. Sci. , vol.72 , pp. 1103-1126
    • Gerlowski, L.E.1    Jain, R.K.2
  • 23
    • 0027275566 scopus 로고
    • Physiological parameters in laboratory animals and humans
    • NY
    • Davies, B., and Morris, T. Physiological parameters in laboratory animals and humans. Pharm. Res. (NY), 10: 1093-1095, 1993.
    • (1993) Pharm. Res. , vol.10 , pp. 1093-1095
    • Davies, B.1    Morris, T.2
  • 24
    • 0018387530 scopus 로고
    • A program package for simulation and parameter estimation in pharmacokinetic systems
    • D'Argenio, D. Z., and Schumitzky, A. A program package for simulation and parameter estimation in pharmacokinetic systems. Comput. Programs Biomed., 9: 115-134, 1979.
    • (1979) Comput. Programs Biomed. , vol.9 , pp. 115-134
    • D'Argenio, D.Z.1    Schumitzky, A.2
  • 25
    • 0023707091 scopus 로고
    • Kinetic analysis of in vivo receptor dependent binding of human epidermal growth factor by rat tissues
    • Kim, D. C., Sugiyama, Y., Satoh, H., Fuwa, T., Iga, T., and Hanano, M. Kinetic analysis of in vivo receptor dependent binding of human epidermal growth factor by rat tissues. J. Pharm. Sci., 77: 200-207, 1988.
    • (1988) J. Pharm. Sci. , vol.77 , pp. 200-207
    • Kim, D.C.1    Sugiyama, Y.2    Satoh, H.3    Fuwa, T.4    Iga, T.5    Hanano, M.6
  • 26
    • 0024571618 scopus 로고
    • Kinetic analysis of the elimination process of human epidermal growth factor in rats
    • Kim, D. C., Sugiyama, Y., Fuwa, T., Sakamoto, S., Iga, T., and Hanano, M. Kinetic analysis of the elimination process of human epidermal growth factor in rats. Biochem. Pharmacol., 38: 241-249, 1989.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 241-249
    • Kim, D.C.1    Sugiyama, Y.2    Fuwa, T.3    Sakamoto, S.4    Iga, T.5    Hanano, M.6
  • 27
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Washington DC
    • Levitzki, A., and Gazit, A. Tyrosine kinase inhibition: an approach to drug development. Science (Washington DC), 267: 1782-1788, 1995.
    • (1995) Science , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 29
    • 0028323606 scopus 로고
    • BE-23372M, a novel and specific inhibitor for epidermal growth factor receptor kinase
    • Tanaka, S., Okabe, T., Chieda, S., Endo, K., Kanoh, T., Okura, A., and Yosida, E. BE-23372M, a novel and specific inhibitor for epidermal growth factor receptor kinase. Jpn. J. Cancer Res., 85: 253-259, 1994.
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 253-259
    • Tanaka, S.1    Okabe, T.2    Chieda, S.3    Endo, K.4    Kanoh, T.5    Okura, A.6    Yosida, E.7
  • 31
    • 0024240990 scopus 로고
    • Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors
    • Washington DC
    • Yaish, P., Gazit, A., Gilon, C., and Levitzki, A. Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors. Science (Washington DC), 242: 933-935, 1988.
    • (1988) Science , vol.242 , pp. 933-935
    • Yaish, P.1    Gazit, A.2    Gilon, C.3    Levitzki, A.4
  • 32
    • 0024385914 scopus 로고
    • Tryphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation
    • Lyall, R. M., Zilberstein, A., Gazit, A., Gilon, C., Levitzki, A., and Schlessinger, J. Tryphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation. J. Biol. Chem., 264: 14503-14509, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 14503-14509
    • Lyall, R.M.1    Zilberstein, A.2    Gazit, A.3    Gilon, C.4    Levitzki, A.5    Schlessinger, J.6
  • 33
    • 0028567131 scopus 로고
    • Inhibition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor genistein
    • Scholar, E. M., and Toews, M. L. Inhibition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor genistein. Cancer Lett., 87: 159-162, 1994.
    • (1994) Cancer Lett. , vol.87 , pp. 159-162
    • Scholar, E.M.1    Toews, M.L.2
  • 34
    • 0027930815 scopus 로고
    • Antiproliferative effect of genistein and Adriamycin against estrogen dependent and -independent human breast carcinoma cell lines
    • Monti, E., and Sinha, B. C. Antiproliferative effect of genistein and Adriamycin against estrogen dependent and -independent human breast carcinoma cell lines. Anticancer Res., 14: 1221-1226, 1994.
    • (1994) Anticancer Res. , vol.14 , pp. 1221-1226
    • Monti, E.1    Sinha, B.C.2
  • 36
    • 0029957108 scopus 로고    scopus 로고
    • Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats
    • Lond.
    • Murrill, W. B., Brown, N. M., Zhang, J. X., Manzolillo, P. A., Barnes, S., and Lamartiniere, C. A. Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats. Carcinogenesis (Lond.), 17: 1451-1457, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 1451-1457
    • Murrill, W.B.1    Brown, N.M.2    Zhang, J.X.3    Manzolillo, P.A.4    Barnes, S.5    Lamartiniere, C.A.6
  • 37
    • 0026077157 scopus 로고
    • The EGF receptor system as a target for antitumor therapy
    • Ennis, B. W., Lippman, M. E., and Dickson, R. B. The EGF receptor system as a target for antitumor therapy. Cancer Invest., 9: 553-562, 1991.
    • (1991) Cancer Invest. , vol.9 , pp. 553-562
    • Ennis, B.W.1    Lippman, M.E.2    Dickson, R.B.3
  • 38
    • 0024998005 scopus 로고
    • The epidermal growth factor receptor as a target for therapy
    • Cold Spring Harbor
    • Harns, A. L. The epidermal growth factor receptor as a target for therapy. Cancer Cells (Cold Spring Harbor), 2: 321-323, 1990.
    • (1990) Cancer Cells , vol.2 , pp. 321-323
    • Harns, A.L.1
  • 39
    • 0026436895 scopus 로고
    • Epidermal growth factor receptor as a target for therapy with anti-receptor monoclonal antibodies
    • Mendelsohn, J. Epidermal growth factor receptor as a target for therapy with anti-receptor monoclonal antibodies. J. Natl. Cancer Inst. Monogr., 13: 125-131, 1992.
    • (1992) J. Natl. Cancer Inst. Monogr. , vol.13 , pp. 125-131
    • Mendelsohn, J.1
  • 40
    • 0028268289 scopus 로고
    • The epidermal growth factor receptor as a target for therapy in breast carcinoma
    • Baselga, J., and Mendelsohn, J. The epidermal growth factor receptor as a target for therapy in breast carcinoma. Breast Cancer Res. Treat., 29: 127-138, 1994.
    • (1994) Breast Cancer Res. Treat. , vol.29 , pp. 127-138
    • Baselga, J.1    Mendelsohn, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.