Modeling Human Digestive Diseases With CRISPR-Cas9–Modified Organoids

Gastroenterology

Volumn 156, Issue 3, 2019, Pages 562-576

  Fujii, Masayuki ^a   Clevers, Hans ^b   Sato, Toshiro ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Colorectal Cancer; Gastric Cancer; Inflammatory Bowel Disease; Pancreatic Cancer

Indexed keywords

CANCER STEM CELL; COLORECTAL CANCER; CRISPR-CAS9 SYSTEM; DIGESTIVE SYSTEM CANCER; DRUG SCREENING; ESOPHAGUS; GASTROINTESTINAL DISEASE; GENE EDITING; HEPATOBILIARY SYSTEM; HUMAN; INDEL MUTATION; LARGE INTESTINE; NONHUMAN; ORGANOID; PANCREAS; PANCREAS CANCER; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVERSE GENETICS; REVIEW; SMALL INTESTINE; STOMACH; STOMACH CANCER; COLORECTAL TUMOR; CRISPR CAS SYSTEM; ESOPHAGUS TUMOR; FEMALE; GASTROINTESTINAL TRACT; GASTROINTESTINAL TUMOR; GENETIC PREDISPOSITION; GENETICS; MALE; PANCREAS TUMOR; PATHOLOGY; SENSITIVITY AND SPECIFICITY;

COLORECTAL NEOPLASMS; CRISPR-CAS SYSTEMS; ESOPHAGEAL NEOPLASMS; FEMALE; GASTROINTESTINAL DISEASES; GASTROINTESTINAL NEOPLASMS; GASTROINTESTINAL TRACT; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; ORGANOIDS; PANCREATIC NEOPLASMS; SENSITIVITY AND SPECIFICITY;

EID: 85060989433     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2018.11.048     Document Type: Review

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