Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts

Development (Cambridge)

Volumn 141, Issue 11, 2014, Pages 2206-2215

  Kabiri, Zahra ^a,b   Greicius, Gediminas ^a,c   Madan, Babita ^a   Biechele, Steffen ^d   Zhong, Zhendong ^e,g   Zaribafzadeh, Hamed ^a   Edison, ^a   Aliyev, Jamal ^a   Wu, Yonghui ^a   Bunte, Ralph ^a   Williams, Bart O ^e   Rossant, Janet ^d   Virshup, David M ^a,b,f  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^d HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^e VAN ANDEL RESEARCH INSTITUTE   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Intestinal niche; Mouse; PORCN; R spondin; Radiation injury; Wnt

Indexed keywords

CELL PROTEIN; R SPONDIN 3 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL REGENERATION; ENDOPLASMIC RETICULUM; EX VIVO STUDY; HOMEOSTASIS; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; PROTEIN SECRETION; RADIATION INJURY; SIGNAL TRANSDUCTION; STEM CELL NICHE; STROMA CELL;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; EPITHELIUM; FIBROBLASTS; GENE DELETION; HEK293 CELLS; HOMEOSTASIS; HUMANS; INTESTINES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PANETH CELLS; SIGNAL TRANSDUCTION; STEM CELL NICHE; STEM CELLS; STROMAL CELLS; THROMBOSPONDINS; WNT PROTEINS;

EID: 84901386333     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.104976     Document Type: Article

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