A distinct role for Lgr5 + stem cells in primary and metastatic colon cancer

Nature

Volumn 543, Issue 7647, 2017, Pages 676-680

  De Sousa E Melo, Felipe ^a   Kurtova, Antonina V ^a   Harnoss, Jonathan M ^a   Kljavin, Noelyn ^a   Hoeck, Joerg D ^a   Hung, Jeffrey ^a   Anderson, Jeffrey Eastham ^a   Storm, Elaine E ^a   Modrusan, Zora ^a   Koeppen, Hartmut ^a   Dijkgraaf, Gerrit J P ^a   Piskol, Robert ^a   De Sauvage, Frederic J ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 5; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; LGR5 PROTEIN, MOUSE; TUMOR MARKER;

AMINO ACID; CANCER; CELLS AND CELL COMPONENTS; DISEASE TREATMENT; GENE EXPRESSION; PROTEIN; RODENT; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER REGRESSION; CANCER STEM CELL; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; LIVER METASTASIS; METASTATIC COLON CANCER; MOUSE; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; CELL SEPARATION; COLORECTAL NEOPLASMS; CYTOPLASM; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; FEMALE; INTESTINE; LIVER NEOPLASMS; METABOLISM; NEOPLASM METASTASIS; PATHOLOGY; SECONDARY; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSPLANTATION;

ANIMALS; BIOMARKERS, TUMOR; CELL PROLIFERATION; CELL SEPARATION; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; INJECTIONS, SUBCUTANEOUS; INTESTINES; LIVER NEOPLASMS; MICE; NEOPLASM METASTASIS; NEOPLASTIC STEM CELLS; ORGANOIDS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 85017964233     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature21713     Document Type: Article

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