Prospective derivation of a living organoid biobank of colorectal cancer patients

Cell

Volumn 161, Issue 4, 2015, Pages 933-945

  Van De Wetering, Marc ^a,b   Francies, Hayley E ^c   Francis, Joshua M ^d,e   Bounova, Gergana ^f   Iorio, Francesco ^c   Pronk, Apollo ^g   Van Houdt, Winan ^g   Van Gorp, Joost ^g   Taylor Weiner, Amaro ^d   Kester, Lennart ^a   McLaren Douglas, Anne ^c   Blokker, Joyce ^a,b   Jaksani, Sridevi ^a,b   Bartfeld, Sina ^a   Volckman, Richard ^h   Van Sluis, Peter ^h   Li, Vivian S W ⁱ   Seepo, Sara ^d   Sekhar Pedamallu, Chandra ^d,e   Cibulskis, Kristian ^d   Carter, Scott L ^d,e   McKenna, Aaron ^d   Lawrence, Michael S ^d   Lichtenstein, Lee ^d   Stewart, Chip ^d   Koster, Jan ^h   Versteeg, Rogier ^h   Van Oudenaarden, Alexander ^a   Saez Rodriguez, Julio ^c   Vries, Robert G J ^a,b   Getz, Gad ^d,e   Wessels, Lodewyk ^f   Stratton, Michael R ^c   McDermott, Ultan ^c   Meyerson, Matthew ^d,e   Garnett, Mathew J ^c   Clevers, Hans ^a,b   more..

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b Foundation Hubrecht Organoid Technology (HUB)   (Netherlands)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f NETHERLANDS CANCER INSTITUTE   (Netherlands)

^g DEPARTMENT OF SURGERY   (Netherlands)

^h UNIVERSITY OF AMSTERDAM   (Netherlands)

ⁱ NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; RNA; WNT PROTEIN; DNA BINDING PROTEIN; ONCOPROTEIN; RNF43 PROTEIN, HUMAN;

ARTICLE; CANCER GENETICS; CANCER PATIENT; CLINICAL ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOPLASM; FEEDBACK SYSTEM; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; WNT SIGNALING PATHWAY; COLORECTAL NEOPLASMS; DRUG EFFECTS; DRUG SCREENING; HEALTH CARE FACILITY; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PERSONALIZED MEDICINE; PROCEDURES;

BIOLOGICAL SPECIMEN BANKS; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; ONCOGENE PROTEINS; ORGAN CULTURE TECHNIQUES; ORGANOIDS; PRECISION MEDICINE;

EID: 84928974420     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.03.053     Document Type: Article

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