A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

Cell Stem Cell

Volumn 18, Issue 6, 2016, Pages 827-838

  Fujii, Masayuki ^a,b   Shimokawa, Mariko ^a   Date, Shoichi ^a,c   Takano, Ai ^a   Matano, Mami ^a   Nanki, Kosaku ^a   Ohta, Yuki ^a   Toshimitsu, Kohta ^a   Nakazato, Yoshihiro ^a   Kawasaki, Kenta ^a   Uraoka, Toshio ^a   Watanabe, Toshiaki ^b   Kanai, Takanori ^a   Sato, Toshiro ^a  

^a KEIO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL LINE; CARCINOGENESIS; CELL CULTURE; CELL DIFFERENTIATION; CELL HETEROGENEITY; COLORECTAL TUMOR; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENOTYPE PHENOTYPE CORRELATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL NICHE; ANIMAL; CYTOPLASM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC HETEROGENEITY; GENETICS; HUMAN GENOME; METABOLISM; MUTATION; NONOBESE DIABETIC MOUSE; PATHOLOGY; SCID MOUSE; TUMOR CELL CULTURE; XENOGRAFT;

EPIDERMAL GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ANIMALS; CARCINOGENESIS; COLORECTAL NEOPLASMS; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC HETEROGENEITY; GENOME, HUMAN; HUMANS; MALE; MICE, INBRED NOD; MICE, SCID; MUTATION; ORGANOIDS; STEM CELL NICHE; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; WNT PROTEINS;

EID: 84971516758     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.04.003     Document Type: Article

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