Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Nature

Volumn 476, Issue 7360, 2011, Pages 293-297

  De Lau, Wim ^a   Barker, Nick ^a,f   Low, Teck Y ^b   Koo, Bon Kyoung ^a   Li, Vivian S W ^a   Teunissen, Hans ^a   Kujala, Pekka ^c   Haegebarth, Andrea ^a,g   Peters, Peter J ^c   Van De Wetering, Marc ^a   Stange, D E ^a   Van Es, J ^a   Guardavaccaro, Daniele ^a   Schasfoort, Richard B M ^d   Mohri, Yasuaki ^e   Nishimori, Katsuhiko ^e   Mohammed, Shabaz ^b   Heck, Albert J R ^b   Clevers, Hans ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^d UNIVERSITY OF TWENTE   (Netherlands)

^e TOHOKU UNIVERSITY   (Japan)

^f INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^g BAYER PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; FRIZZLED PROTEIN; LGR4 PROTEIN; LGR5 PROTEIN; LGR6 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3A PROTEIN;

ADULT; CELL ORGANELLE; FUNCTIONAL MORPHOLOGY; GENE EXPRESSION; HOMOLOGY; INHIBITION; MASS SPECTROMETRY; RODENT; SIGNALING; SOLUBILIZATION;

ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; COMPLEX FORMATION; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; INTESTINE; INTESTINE CRYPT; INTRACELLULAR SIGNALING; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION;

ADULT STEM CELLS; ANIMALS; CELLS, CULTURED; EPITHELIAL CELLS; FRIZZLED RECEPTORS; GENE DELETION; HEK293 CELLS; HUMANS; MICE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; REGENERATION; SIGNAL TRANSDUCTION; THROMBOSPONDINS; WNT PROTEINS;

EID: 80051926611     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10337     Document Type: Article

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