Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5 + stem cell

Nature Medicine

Volumn 18, Issue 4, 2012, Pages 618-623

  Yui, Shiro ^a   Nakamura, Tetsuya ^a   Sato, Toshiro ^b,c   Nemoto, Yasuhiro ^a   Mizutani, Tomohiro ^a   Zheng, Xiu ^a   Ichinose, Shizuko ^a   Nagaishi, Takashi ^a   Okamoto, Ryuichi ^a   Tsuchiya, Kiichiro ^a   Clevers, Hans ^b   Watanabe, Mamoru ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CHROMOGRANIN A; EPIDERMAL GROWTH FACTOR; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 5; MUCIN 2; NOGGIN; NOTCH RECEPTOR; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL GROWTH; COLON MUCOSA; CONTROLLED STUDY; CRYPT CELL; ENGRAFTMENT; FEASIBILITY STUDY; FEMALE; IN VITRO STUDY; LGR5 STEM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; STEM CELL TRANSPLANTATION; TRANSGENIC MOUSE;

ADULT STEM CELLS; ANIMALS; BODY WEIGHT; CELLS, CULTURED; CHROMOGRANIN A; COLON; CYCLOOXYGENASE 1; DNA-BINDING PROTEINS; EPITHELIUM; GREEN FLUORESCENT PROTEINS; KI-67 ANTIGEN; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; ORGANOIDS; RECEPTORS, G-PROTEIN-COUPLED; RHODAMINES; TIME FACTORS; TRANSPLANTS;

MUS;

EID: 84862777784     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2695     Document Type: Article

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