Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids

Nature Communications

Volumn 7, Issue , 2016, Pages

  Jardé, Thierry ^a,b,c   Lloyd Lewis, Bethan ^a,d   Thomas, Mairian ^a   Kendrick, Howard ^a   Melchor, Lorenzo ^e   Bougaret, Lauriane ^a   Watson, Peter D ^a   Ewan, Kenneth ^a   Smalley, Matthew J ^a   Dale, Trevor C ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b MONASH UNIVERSITY   (Australia)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BETA CATENIN; CD24 ANTIGEN; CLOSTRIDIOPEPTIDASE A; CYTOKERATIN 14; CYTOKERATIN 8; DOXYCYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; ESTROGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; NEU DIFFERENTIATION FACTOR; NOGGIN; OSTEOCLAST DIFFERENTIATION FACTOR; PENICILLIN DERIVATIVE; PROGESTERONE; PROGESTERONE RECEPTOR; PROTEIN P63; R SPONDIN 1; SCATTER FACTOR; SMOOTH MUSCLE ACTIN; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1; STEROID RECEPTOR; STREPTOMYCIN; TANKYRASE; UNCLASSIFIED DRUG; WNT PROTEIN; WNT4 PROTEIN; ERBB3 PROTEIN, MOUSE; ERBB4 PROTEIN, MOUSE;

BIOLOGICAL DEVELOPMENT; GENETIC ANALYSIS; GENETIC DIFFERENTIATION; HORMONE; LABORATORY METHOD; MAMMAL; PROTEIN; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; STEROID; TUMOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL; BREAST CARCINOGENESIS; BREAST EPITHELIUM CELL; CELL CULTURE; CELL POPULATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOPLASM; EX VIVO STUDY; FEMALE; HORMONE ACTION; IN VITRO STUDY; IN VIVO STUDY; MAMMARY GLAND; MOLECULAR BIOLOGY; MOUSE; MOUSE MAMMARY TUMOR VIRUS; NONHUMAN; SIGNAL TRANSDUCTION; STEM CELL; THREE DIMENSIONAL IMAGING; THREE DIMENSIONAL MAMMARY CULTURE; TISSUE CULTURE; WNT SIGNALING PATHWAY; ANIMAL; C57BL MOUSE; CONFOCAL MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; KARYOTYPING; METABOLISM; ORGANOID; PROCEDURES; TIME LAPSE IMAGING; TISSUE CULTURE TECHNIQUE; UDDER; WNT SIGNALING;

MOUSE MAMMARY TUMOR VIRUS;

ANIMALS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; KARYOTYPING; MAMMARY GLANDS, ANIMAL; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; NEUREGULIN-1; ORGANOIDS; RECEPTOR, ERBB-3; RECEPTOR, ERBB-4; TIME-LAPSE IMAGING; TISSUE CULTURE TECHNIQUES; WNT SIGNALING PATHWAY;

EID: 84992593504     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13207     Document Type: Article

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