Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR

Genome Biology

Volumn 17, Issue 1, 2016, Pages

  Haeussler, Maximilian ^a   Schönig, Kai ^b   Eckert, Hélène ^c   Eschstruth, Alexis ^d   Mianné, Joffrey ^e   Renaud, Jean Baptiste ^f   Schneider Maunoury, Sylvie ^d   Shkumatava, Alena ^c   Teboul, Lydia ^e   Kent, Jim ^a   Joly, Jean Stephane ^f   Concordet, Jean Paul ^g  

^a University of California Santa Cruz   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c INSTITUT CURIE   (France)

^d SORBONNE UNIVERSITÉ   (France)

^e Medical Research Council Harwell Institute   (United Kingdom)

^f Université Paris Saclay   (France)

^g MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GUIDE RNA; SMALL NUCLEAR RNA; U6 SMALL NUCLEAR RNA;

ALGORITHM; ARTICLE; COMPUTER PREDICTION; COMPUTER PROGRAM; CRISPR CAS SYSTEM; FALSE POSITIVE RESULT; GENOME; INFORMATION SERVICE; INTERNET; MUTATION RATE; NONHUMAN; PROMOTER REGION; RNA TRANSCRIPTION; SCORING SYSTEM; ZEBRA FISH; GENE EDITING; GENETICS; SOFTWARE;

ALGORITHMS; CRISPR-CAS SYSTEMS; GENE EDITING; GENOME; INTERNET; PROMOTER REGIONS, GENETIC; RNA, GUIDE; RNA, SMALL NUCLEAR; SOFTWARE;

EID: 84977522458     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-1012-2     Document Type: Article

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