Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

Cancer Cell

Volumn 32, Issue 2, 2017, Pages 185-203.e13

  Raphael, Benjamin J ^a   Hruban, Ralph H ^a   Aguirre, Andrew J ^a   Moffitt, Richard A ^a   Yeh, Jen Jen ^a   Stewart, Chip ^a   Robertson, A Gordon ^a   Cherniack, Andrew D ^a   Gupta, Manaswi ^a   Getz, Gad ^a   Gabriel, Stacey B ^a   Meyerson, Matthew ^a   Cibulskis, Carrie ^a   Fei, Suzanne S ^a   Hinoue, Toshinori ^a   Shen, Hui ^a   Laird, Peter W ^a   Ling, Shiyun ^a   Lu, Yiling ^a   Mills, Gordon B ^a   Akbani, Rehan ^a   Loher, Phillipe ^a   Londin, Eric R ^a   Rigoutsos, Isidore ^a   Telonis, Aristeidis G ^a   Gibb, Ewan A ^a   Goldenberg, Anna ^a   Mezlini, Aziz M ^a   Hoadley, Katherine A ^a   Collisson, Eric ^a   Lander, Eric ^a   Murray, Bradley A ^a   Hess, Julian ^a   Rosenberg, Mara ^a   Bergelson, Louis ^a   Zhang, Hailei ^a   Cho, Juok ^a   Tiao, Grace ^a   Kim, Jaegil ^a   Livitz, Dimitri ^a   Leshchiner, Ignaty ^a   Reardon, Brendan ^a   Van Allen, Eliezer ^a   Kamburov, Atanas ^a   Beroukhim, Rameen ^a   Saksena, Gordon ^a   Schumacher, Steven E ^a   Noble, Michael S ^a   Heiman, David I ^a   Gehlenborg, Nils ^a   Lawrence, Michael S ^a   Adsay, Volkan ^a   Petersen, Gloria ^a   Klimstra, David ^a   Bardeesy, Nabeel ^a   Leiserson, Mark D M ^a   Bowlby, Reanne ^a   Kasaian, Katayoon ^a   Birol, Inanc ^a   Mungall, Karen L ^a   Sadeghi, Sara ^a   Weinstein, John N ^a   Spellman, Paul T ^a   Liu, Yuexin ^a   Amundadottir, Laufey T ^a   Tepper, Joel ^a   Singhi, Aatur D ^a   Dhir, Rajiv ^a   Paul, Drwiega ^a   Smyrk, Thomas ^a   Zhang, Lizhi ^a   Kim, Paula ^a   Bowen, Jay ^a   Frick, Jessica ^a   Gastier Foster, Julie M ^a   Gerken, Mark ^a   Lau, Kevin ^a   Leraas, Kristen M ^a   Lichtenberg, Tara M ^a   Ramirez, Nilsa C ^a   Renkel, Jeremy ^a   Sherman, Mark ^a   Wise, Lisa ^a   Yena, Peggy ^a   Zmuda, Erik ^a   Shih, Juliann ^a   Ally, Adrian ^a   Balasundaram, Miruna ^a   Carlsen, Rebecca ^a   Chu, Andy ^a   Chuah, Eric ^a   Clarke, Amanda ^a   Dhalla, Noreen ^a   Holt, Robert A ^a   Jones, Steven J M ^a   Lee, Darlene ^a   Ma, Yussanne ^a   Marra, Marco A ^a   Mayo, Michael ^a   Moore, Richard A ^a   Mungall, Andrew J ^a   Schein, Jacqueline E ^a   Sipahimalani, Payal ^a   Tam, Angela ^a   Thiessen, Nina ^a   Tse, Kane ^a   Wong, Tina ^a   Brooks, Denise ^a   Auman, J Todd ^a   Balu, Saianand ^a   Bodenheimer, Tom ^a   Hayes, D Neil ^a   Hoyle, Alan P ^a   Jefferys, Stuart R ^a   Jones, Corbin D ^a   Meng, Shaowu ^a   Mieczkowski, Piotr A ^a   Mose, Lisle E ^a   Perou, Charles M ^a   Perou, Amy H ^a   Roach, Jeffrey ^a   Shi, Yan ^a   Simons, Janae V ^a   Skelly, Tara ^a   Soloway, Matthew G ^a   Tan, Donghui ^a   Veluvolu, Umadevi ^a   Parker, Joel S ^a   Wilkerson, Matthew D ^a   Korkut, Anil ^a   Senbabaoglu, Yasin ^a   Burch, Patrick ^a   McWilliams, Robert ^a   Chaffee, Kari ^a   Oberg, Ann ^a   Zhang, Wei ^a   Gingras, Marie Claude ^a   Wheeler, David A ^a   Xi, Liu ^a   Albert, Monique ^a   Bartlett, John ^a   Sekhon, Harman ^a   Stephen, Yeager ^a   Howard, Zaren ^a   Judy, Miller ^a   Breggia, Anne ^a   Shroff, Rachna T ^a   Chudamani, Sudha ^a   Liu, Jia ^a   Lolla, Laxmi ^a   Naresh, Rashi ^a   Pihl, Todd ^a   Sun, Qiang ^a   Wan, Yunhu ^a   Wu, Ye ^a   Jennifer, Smith ^a   Roggin, Kevin ^a   Becker, Karl Friedrich ^a   Behera, Madhusmita ^a   Bennett, Joseph ^a   Boice, Lori ^a   Burks, Eric ^a   Carlotti Junior, Carlos Gilberto ^a   Chabot, John ^a   Pretti da Cunha Tirapelli, Daniela ^a   Sebastião dos Santos, Jose ^a   Dubina, Michael ^a   Eschbacher, Jennifer ^a   Huang, Mei ^a   Huelsenbeck Dill, Lori ^a   Jenkins, Roger ^a   Karpov, Alexey ^a   Kemp, Rafael ^a   Lyadov, Vladimir ^a   Maithel, Shishir ^a   Manikhas, Georgy ^a   Montgomery, Eric ^a   Noushmehr, Houtan ^a   Osunkoya, Adeboye ^a   Owonikoko, Taofeek ^a   Paklina, Oxana ^a   Potapova, Olga ^a   Ramalingam, Suresh ^a   Rathmell, W Kimryn ^a   Rieger Christ, Kimberly ^a   Saller, Charles ^a   Setdikova, Galiya ^a   Shabunin, Alexey ^a   Sica, Gabriel ^a   Su, Tao ^a   Sullivan, Travis ^a   Swanson, Pat ^a   Tarvin, Katherine ^a   Tavobilov, Michael ^a   Thorne, Leigh B ^a   Urbanski, Stefan ^a   Voronina, Olga ^a   Wang, Timothy ^a   Crain, Daniel ^a   Curley, Erin ^a   Gardner, Johanna ^a   Mallery, David ^a   Morris, Scott ^a   Paulauskis, Joseph ^a   Penny, Robert ^a   Shelton, Candace ^a   Shelton, Troy ^a   Janssen, Klaus Peter ^a   Bathe, Oliver ^a   Bahary, Nathan ^a   Slotta Huspenina, Julia ^a   Johns, Amber ^a   Hibshoosh, Hanina ^a   Hwang, Rosa F ^a   Sepulveda, Antonia ^a   Radenbaugh, Amie ^a   Baylin, Stephen B ^a   Berrios, Mario ^a   Bootwalla, Moiz S ^a   Holbrook, Andrea ^a   Lai, Phillip H ^a   Maglinte, Dennis T ^a   Mahurkar, Swapna ^a   Triche, Timothy J ^a   Van Den Berg, David J ^a   Weisenberger, Daniel J ^a   Chin, Lynda ^a,a   Kucherlapati, Raju ^a   Kucherlapati, Melanie ^a   Pantazi, Angeliki ^a   Park, Peter ^a   Voet, Doug ^a   Lin, Pei ^a   Frazer, Scott ^a   Defreitas, Timothy ^a   Meier, Sam ^a   Kwon, Sun Young ^a   Kim, Yong Hoon ^a   Park, Sang Jae ^a   Han, Sung Sik ^a   Kim, Seong Hoon ^a   Kim, Hark ^a   Furth, Emma ^a   Tempero, Margaret ^a   Sander, Chris ^a   Biankin, Andrew ^a   Chang, David ^a   Bailey, Peter ^a   Gill, Anthony ^a   Kench, James ^a   Grimmond, Sean ^a   more..

^a APGI, Australian Pancreatic

Author keywords

genomics; heterogeneity; KRAS; miRNA; molecular subtypes; pancreatic cancer; PDAC; RPPA; TCGA; tumor cellularity

Indexed keywords

AT RICH INTERACTIVE DOMAIN CONTAINING PROTEIN 1A; B RAF KINASE; BETA CATENIN; CATENIN BETA 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GUANINE NUCLEOTIDE BINDING PROTEIN; K RAS PROTEIN; LONG UNTRANSLATED RNA; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MICRORNA; POLYBROMO 1; PROTEIN P53; RAS PROTEIN; RAS RESPONSIVE ELEMENT BINDING PROTEIN 1C; RING FINGER PROTEIN; RING FINGER PROTEIN 43; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG; UNTRANSLATED RNA; KRAS PROTEIN, HUMAN; PROTEIN P21; PROTEOME; TRANSCRIPTOME;

ARTICLE; CANCER GENETICS; CANCER IMMUNOTHERAPY; CANCER PATIENT; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; COPY NUMBER VARIATION; DNA METHYLATION; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FOLLOW UP; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOMICS; GERMLINE MUTATION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MISSENSE MUTATION; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PREVALENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; RNA SEQUENCE; SIGNAL TRANSDUCTION; SOMATIC MUTATION; TRANSCRIPTOMICS; WHOLE EXOME SEQUENCING; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; MUTATION; PANCREAS CARCINOMA; PANCREAS TUMOR; PROCEDURES;

CARCINOMA, PANCREATIC DUCTAL; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMICS; HUMANS; MUTATION; PANCREATIC NEOPLASMS; PROTEOME; PROTO-ONCOGENE PROTEINS P21(RAS); TRANSCRIPTOME;

EID: 85026888109     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2017.07.007     Document Type: Article

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