25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 39, 2009, Pages 16764-16769

  Bauman, David R ^a   Bitmansour, Andrew D ^b   McDonald, Jeffrey G ^a   Thompson, Bonne M ^a   Liang, Guosheng ^a   Russell, David W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Adaptive immune system; Cholesterol 25 hydroxylase; Innate immune system; Negative regulation oxysterol

Indexed keywords

25 HYDROXYCHOLESTEROL; IMMUNOGLOBULIN A; INTERLEUKIN 2; OXYGENASE; OXYSTEROL 7 ALPHA HYDROXYLASE; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNE SYSTEM; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; B-LYMPHOCYTES; CYTOKINES; HYDROXYCHOLESTEROLS; IMMUNOGLOBULIN A; MACROPHAGES; MICE; MICE, TRANSGENIC; STEROID HYDROXYLASES; TOLL-LIKE RECEPTORS;

MAMMALIA;

EID: 70349730033     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0909142106     Document Type: Article

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