-
1
-
-
35448963836
-
Nonalcoholic fatty liver disease as a complication of insulin resistance
-
Abdelmalek MF, Diehl AM (2007) Nonalcoholic fatty liver disease as a complication of insulin resistance. Med Clin North Am 91(6): 1125-1149
-
(2007)
Med Clin North Am
, vol.91
, Issue.6
, pp. 1125-1149
-
-
Abdelmalek, M.F.1
Diehl, A.M.2
-
2
-
-
0030939116
-
Human acetyl-CoA carboxylase 2 molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms
-
Abu-Elheiga L, Almarza-Ortega DB, Baldini A, Wakil SJ (1997) Human acetyl-CoA carboxylase 2 molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms. J Biol Chem 272(16): 10669-10677
-
(1997)
J Biol Chem
, vol.272
, Issue.16
, pp. 10669-10677
-
-
Abu-Elheiga, L.1
Almarza-Ortega, D.B.2
Baldini, A.3
Wakil, S.J.4
-
3
-
-
24744448667
-
Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal
-
Abu-Elheiga L, Matzuk MM, Kordari P, Oh W, Shaikenov T, Gu Z, Wakil SJ (2005) Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proc Natl Acad Sci U S A 102(34): 12011-12016
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.34
, pp. 12011-12016
-
-
Abu-Elheiga, L.1
Matzuk, M.M.2
Kordari, P.3
Oh, W.4
Shaikenov, T.5
Gu, Z.6
Wakil, S.J.7
-
4
-
-
84902551389
-
De novo lipogenesis in health and disease
-
Ameer F, Scandiuzzi L, Hasnain S, Kalbacher H, Zaidi N (2014) De novo lipogenesis in health and disease. Metabolism 63(7): 895-902
-
(2014)
Metabolism
, vol.63
, Issue.7
, pp. 895-902
-
-
Ameer, F.1
Scandiuzzi, L.2
Hasnain, S.3
Kalbacher, H.4
Zaidi, N.5
-
5
-
-
0034613175
-
Promoter analysis of the mouse sterol regulatory element- binding protein-1c gene
-
Amemiya-Kudo M, Shimano H, Yoshikawa T, Yahagi N, Hasty AH, Okazaki H, Tamura Y, Shionoiri F, Iizuka Y, Ohashi K (2000) Promoter analysis of the mouse sterol regulatory element- binding protein-1c gene. J Biol Chem 275(40): 31078-31085
-
(2000)
J Biol Chem
, vol.275
, Issue.40
, pp. 31078-31085
-
-
Amemiya-Kudo, M.1
Shimano, H.2
Yoshikawa, T.3
Yahagi, N.4
Hasty, A.H.5
Okazaki, H.6
Tamura, Y.7
Shionoiri, F.8
Iizuka, Y.9
Ohashi, K.10
-
6
-
-
77954579285
-
Decrease in membrane phospholipid unsaturation induces unfolded protein response
-
Ariyama H, Kono N, Matsuda S, Inoue T, Arai H (2010) Decrease in membrane phospholipid unsaturation induces unfolded protein response. J Biol Chem 285(29): 22027-22035
-
(2010)
J Biol Chem
, vol.285
, Issue.29
, pp. 22027-22035
-
-
Ariyama, H.1
Kono, N.2
Matsuda, S.3
Inoue, T.4
Arai, H.5
-
7
-
-
79551534130
-
Crosstalk between components of circadian and metabolic cycles in mammals
-
Asher G, Schibler U (2011) Crosstalk between components of circadian and metabolic cycles in mammals. Cell Metab 13(2): 125-137
-
(2011)
Cell Metab
, vol.13
, Issue.2
, pp. 125-137
-
-
Asher, G.1
Schibler, U.2
-
8
-
-
37649030647
-
Genetic manipulations of PPARs: Effects on obesity and metabolic disease
-
Barak Y, Kim S (2007) Genetic manipulations of PPARs: effects on obesity and metabolic disease. PPAR Res 2007: 12781
-
(2007)
PPAR Res
, vol.2007
, pp. 12781
-
-
Barak, Y.1
Kim, S.2
-
9
-
-
0842287450
-
Mitochondrial β-oxidation
-
Bartlett K, Eaton S (2004) Mitochondrial β-oxidation. Eur J Biochem 271(3): 462-469
-
(2004)
Eur J Biochem
, vol.271
, Issue.3
, pp. 462-469
-
-
Bartlett, K.1
Eaton, S.2
-
10
-
-
34548580317
-
Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells
-
Beckers A, Organe S, Timmermans L, Scheys K, Peeters A, Brusselmans K, Verhoeven G, Swinnen JV (2007) Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells. Cancer Res 67(17): 8180-8187
-
(2007)
Cancer Res
, vol.67
, Issue.17
, pp. 8180-8187
-
-
Beckers, A.1
Organe, S.2
Timmermans, L.3
Scheys, K.4
Peeters, A.5
Brusselmans, K.6
Verhoeven, G.7
Swinnen, J.V.8
-
11
-
-
65549140251
-
A phosphorylation cascade controls the degradation of active SREBP1
-
Bengoechea-Alonso MT, Ericsson J (2009) A phosphorylation cascade controls the degradation of active SREBP1. J Biol Chem 284(9): 5885-5895
-
(2009)
J Biol Chem
, vol.284
, Issue.9
, pp. 5885-5895
-
-
Bengoechea-Alonso, M.T.1
Ericsson, J.2
-
12
-
-
84861809881
-
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
-
Benhamed F, Denechaud P-D, Lemoine M, Robichon C, Moldes M, Bertrand-Michel J, Ratziu V, Serfaty L, Housset C, Capeau J (2012) The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans. J Clin Invest 122(6): 2176-2194
-
(2012)
J Clin Invest
, vol.122
, Issue.6
, pp. 2176-2194
-
-
Benhamed, F.1
Denechaud, P.-D.2
Lemoine, M.3
Robichon, C.4
Moldes, M.5
Bertrand-Michel, J.6
Ratziu, V.7
Serfaty, L.8
Housset, C.9
Capeau, J.10
-
13
-
-
0026602720
-
Cis-regulation of the L-type pyruvate kinase gene promoter by glucose, insulin and cyclic AMP
-
Bergot M-O, Diaz-Guerra M-JM, Puzenat N, Raymondjean M, Kahn A (1992) Cis-regulation of the L-type pyruvate kinase gene promoter by glucose, insulin and cyclic AMP. Nucleic Acids Res 20(8): 1871-1878
-
(1992)
Nucleic Acids Res
, vol.20
, Issue.8
, pp. 1871-1878
-
-
Bergot, M.-O.1
Diaz-Guerra, M.-J.M.2
Puzenat, N.3
Raymondjean, M.4
Kahn, A.5
-
14
-
-
0018214611
-
Carbohydrate storage in man: Speculations and some quantitative considerations
-
Björntorp P, Sjöström L (1978) Carbohydrate storage in man: speculations and some quantitative considerations. Metabolism 27(12): 1853-1865
-
(1978)
Metabolism
, vol.27
, Issue.12
, pp. 1853-1865
-
-
Björntorp, P.1
Sjöström, L.2
-
15
-
-
55849112292
-
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation
-
Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, Romero M, Cavener DR, Thompson CB, Diehl JA (2008) PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation. Proc Natl Acad Sci U S A 105(42): 16314-16319
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.42
, pp. 16314-16319
-
-
Bobrovnikova-Marjon, E.1
Hatzivassiliou, G.2
Grigoriadou, C.3
Romero, M.4
Cavener, D.R.5
Thompson, C.B.6
Diehl, J.A.7
-
16
-
-
84872375449
-
Endoplasmic reticulum and the unfolded protein response: Dynamics and metabolic integration
-
Bravo R, Parra V, Gatica D, Rodriguez AE, Torrealba N, Paredes F, Wang ZV, Zorzano A, Hill JA, Jaimovich E (2013) Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration. Int Rev Cell Mol Biol 301: 215
-
(2013)
Int Rev Cell Mol Biol
, vol.301
, pp. 215
-
-
Bravo, R.1
Parra, V.2
Gatica, D.3
Rodriguez, A.E.4
Torrealba, N.5
Paredes, F.6
Wang, Z.V.7
Zorzano, A.8
Hill, J.A.9
Jaimovich, E.10
-
17
-
-
78649855297
-
Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
-
Bricambert J, Miranda J, Benhamed F, Girard J, Postic C, Dentin R (2010) Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice. J Clin Invest 120(12): 4316-4331
-
(2010)
J Clin Invest
, vol.120
, Issue.12
, pp. 4316-4331
-
-
Bricambert, J.1
Miranda, J.2
Benhamed, F.3
Girard, J.4
Postic, C.5
Dentin, R.6
-
18
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown MS, Goldstein JL (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89(3): 331-340
-
(1997)
Cell
, vol.89
, Issue.3
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
19
-
-
38649116056
-
Selective versus total insulin resistance: A pathogenic paradox
-
Brown MS, Goldstein JL (2008) Selective versus total insulin resistance: a pathogenic paradox. Cell Metab 7(2): 95-96
-
(2008)
Cell Metab
, vol.7
, Issue.2
, pp. 95-96
-
-
Brown, M.S.1
Goldstein, J.L.2
-
20
-
-
1942518727
-
Preserved direct hepatic insulin action in rats with diet-induced hepatic steatosis
-
Buettner R, Ottinger I, Schölmerich J, Bollheimer LC (2004) Preserved direct hepatic insulin action in rats with diet-induced hepatic steatosis. Am J Physiol Endocrinol Metab 286(5): E828-E833
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
, Issue.5
, pp. E828-E833
-
-
Buettner, R.1
Ottinger, I.2
Schölmerich, J.3
Bollheimer, L.C.4
-
21
-
-
84859329911
-
Reverbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function
-
Bugge A, Feng D, Everett LJ, Briggs ER, Mullican SE, Wang F, Jager J, Lazar MA (2012) Reverbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function. Genes Dev 26(7): 657-667
-
(2012)
Genes Dev
, vol.26
, Issue.7
, pp. 657-667
-
-
Bugge, A.1
Feng, D.2
Everett, L.J.3
Briggs, E.R.4
Mullican, S.E.5
Wang, F.6
Jager, J.7
Lazar, M.A.8
-
22
-
-
0034704203
-
Mop3 is an essential component of the master circadian pacemaker in mammals
-
Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, Hogenesch JB, Simon MC, Takahashi JS, Bradfield CA (2000) Mop3 is an essential component of the master circadian pacemaker in mammals. Cell 103(7): 1009-1017
-
(2000)
Cell
, vol.103
, Issue.7
, pp. 1009-1017
-
-
Bunger, M.K.1
Wilsbacher, L.D.2
Moran, S.M.3
Clendenin, C.4
Radcliffe, L.A.5
Hogenesch, J.B.6
Simon, M.C.7
Takahashi, J.S.8
Bradfield, C.A.9
-
23
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
-
Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB. Nat Med 11(2): 183-190
-
(2005)
Nat Med
, vol.11
, Issue.2
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
24
-
-
77955129487
-
Liver x receptor signaling pathways and atherosclerosis
-
Calkin AC, Tontonoz P (2010) Liver x receptor signaling pathways and atherosclerosis. Arterioscler Thromb Vasc Biol 30(8): 1513-1518
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, Issue.8
, pp. 1513-1518
-
-
Calkin, A.C.1
Tontonoz, P.2
-
25
-
-
79952312698
-
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma
-
Calvisi DF, Wang C, Ho C, Ladu S, Lee SA, Mattu S, Destefanis G, Delogu S, Zimmermann A, Ericsson J (2011) Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma. Gastroenterology 140(3): 1071-1083.e1075
-
(2011)
Gastroenterology
, vol.140
, Issue.3
, pp. 1071
-
-
Calvisi, D.F.1
Wang, C.2
Ho, C.3
Ladu, S.4
Lee, S.A.5
Mattu, S.6
Destefanis, G.7
Delogu, S.8
Zimmermann, A.9
Ericsson, J.10
-
26
-
-
22544480378
-
"New" hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis
-
Chakravarthy MV, Pan Z, Zhu Y, Tordjman K, Schneider JG, Coleman T, Turk J, Semenkovich CF (2005) "New" hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis. Cell Metab 1(5): 309-322
-
(2005)
Cell Metab
, vol.1
, Issue.5
, pp. 309-322
-
-
Chakravarthy, M.V.1
Pan, Z.2
Zhu, Y.3
Tordjman, K.4
Schneider, J.G.5
Coleman, T.6
Turk, J.7
Semenkovich, C.F.8
-
27
-
-
3843061127
-
Central role for liver X receptor in insulin- mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
-
Chen G, Liang G, Ou J, Goldstein JL, Brown MS (2004) Central role for liver X receptor in insulin- mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc Natl Acad Sci U S A 101(31): 11245-11250
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.31
, pp. 11245-11250
-
-
Chen, G.1
Liang, G.2
Ou, J.3
Goldstein, J.L.4
Brown, M.S.5
-
28
-
-
84860264490
-
Regulation of circadian behaviour and metabolism by REV-ERB-[agr] and REV-ERB-[bgr]
-
Cho H, Zhao X, Hatori M, Ruth TY, Barish GD, Lam MT, Chong L-W, DiTacchio L, Atkins AR, Glass CK (2012) Regulation of circadian behaviour and metabolism by REV-ERB-[agr] and REV-ERB-[bgr]. Nature 485(7396): 123-127
-
(2012)
Nature
, vol.485
, Issue.7396
, pp. 123-127
-
-
Cho, H.1
Zhao, X.2
Hatori, M.3
Ruth, T.Y.4
Barish, G.D.5
Lam, M.T.6
Chong, L.-W.7
DiTacchio, L.8
Atkins, A.R.9
Glass, C.K.10
-
29
-
-
0037067570
-
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss
-
Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM (2002) Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science 297(5579): 240-243
-
(2002)
Science
, vol.297
, Issue.5579
, pp. 240-243
-
-
Cohen, P.1
Miyazaki, M.2
Socci, N.D.3
Hagge-Greenberg, A.4
Liedtke, W.5
Soukas, A.A.6
Sharma, R.7
Hudgins, L.C.8
Ntambi, J.M.9
Friedman, J.M.10
-
30
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378(6559): 785-789
-
(1995)
Nature
, vol.378
, Issue.6559
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
31
-
-
0027168693
-
Exploration of a liver-specific, glucose/insulinresponsive promoter in transgenic mice
-
Cuif M, Porteu A, Kahn A, Vaulont S (1993) Exploration of a liver-specific, glucose/insulinresponsive promoter in transgenic mice. J Biol Chem 268(19): 13769-13772
-
(1993)
J Biol Chem
, vol.268
, Issue.19
, pp. 13769-13772
-
-
Cuif, M.1
Porteu, A.2
Kahn, A.3
Vaulont, S.4
-
32
-
-
84881372774
-
Cellular fatty acid metabolism and cancer
-
Currie E, Schulze A, Zechner R, Walther TC, Farese RV (2013) Cellular fatty acid metabolism and cancer. Cell Metab 18(2): 153-161
-
(2013)
Cell Metab
, vol.18
, Issue.2
, pp. 153-161
-
-
Currie, E.1
Schulze, A.2
Zechner, R.3
Walther, T.C.4
Farese, R.V.5
-
33
-
-
77957553171
-
Activation and repression of glucose-stimulated ChREBP requires the concerted action of multiple domains within the MondoA conserved region
-
Davies MN, O’Callaghan BL, Towle HC (2010) Activation and repression of glucose-stimulated ChREBP requires the concerted action of multiple domains within the MondoA conserved region. Am J Physiol Endocrinol Metab 299(4): E665-E674
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, Issue.4
, pp. E665-E674
-
-
Davies, M.N.1
O’Callaghan, B.L.2
Towle, H.C.3
-
34
-
-
2442489891
-
Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression
-
Dentin R, Pégorier J-P, Benhamed F, Foufelle F, Ferré P, Fauveau V, Magnuson MA, Girard J, Postic C (2004) Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. J Biol Chem 279(19): 20314-20326
-
(2004)
J Biol Chem
, vol.279
, Issue.19
, pp. 20314-20326
-
-
Dentin, R.1
Pégorier, J.-P.2
Benhamed, F.3
Foufelle, F.4
Ferré, P.5
Fauveau, V.6
Magnuson, M.A.7
Girard, J.8
Postic, C.9
-
35
-
-
26444434340
-
Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation
-
Dentin R, Benhamed F, Pégorier J-P, Foufelle F, Viollet B, Vaulont S, Girard J, Postic C (2005) Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation. J Clin Invest 115(10): 2843-2854
-
(2005)
J Clin Invest
, vol.115
, Issue.10
, pp. 2843-2854
-
-
Dentin, R.1
Benhamed, F.2
Pégorier, J.-P.3
Foufelle, F.4
Viollet, B.5
Vaulont, S.6
Girard, J.7
Postic, C.8
-
36
-
-
33749370739
-
Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice
-
Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C (2006) Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice. Diabetes 55(8): 2159-2170
-
(2006)
Diabetes
, vol.55
, Issue.8
, pp. 2159-2170
-
-
Dentin, R.1
Benhamed, F.2
Hainault, I.3
Fauveau, V.4
Foufelle, F.5
Dyck, J.R.6
Girard, J.7
Postic, C.8
-
37
-
-
84862001109
-
Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity
-
Dentin R, Langin D, Postic C (2012) Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity. Cell Metab 15(6): 795-797
-
(2012)
Cell Metab
, vol.15
, Issue.6
, pp. 795-797
-
-
Dentin, R.1
Langin, D.2
Postic, C.3
-
38
-
-
70350545722
-
Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1
-
Dibble CC, Asara JM, Manning BD (2009) Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1. Mol Cell Biol 29(21): 5657-5670
-
(2009)
Mol Cell Biol
, vol.29
, Issue.21
, pp. 5657-5670
-
-
Dibble, C.C.1
Asara, J.M.2
Manning, B.D.3
-
39
-
-
0028206043
-
Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter
-
Doiron B, Cuif M-H, Kahn A, Diaz-Guerra M (1994) Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter. J Biol Chem 269(14): 10213-10216
-
(1994)
J Biol Chem
, vol.269
, Issue.14
, pp. 10213-10216
-
-
Doiron, B.1
Cuif, M.-H.2
Kahn, A.3
Diaz-Guerra, M.4
-
40
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ (2005) Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115(5): 1343
-
(2005)
J Clin Invest
, vol.115
, Issue.5
, pp. 1343
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
41
-
-
77955483125
-
Activation of a metabolic gene regulatory network downstream of mTOR complex 1
-
Düvel K, Yecies JL, Menon S, Raman P, Lipovsky AI, Souza AL, Triantafellow E, Ma Q, Gorski R, Cleaver S (2010) Activation of a metabolic gene regulatory network downstream of mTOR complex 1. Mol Cell 39(2): 171-183
-
(2010)
Mol Cell
, vol.39
, Issue.2
, pp. 171-183
-
-
Düvel, K.1
Yecies, J.L.2
Menon, S.3
Raman, P.4
Lipovsky, A.I.5
Souza, A.L.6
Triantafellow, E.7
Ma, Q.8
Gorski, R.9
Cleaver, S.10
-
42
-
-
84874600898
-
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health
-
Eissing L, Scherer T, Tödter K, Knippschild U, Greve JW, Buurman WA, Pinnschmidt HO, Rensen SS, Wolf AM, Bartelt A (2013) De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health. Nat Commun 4: 1528
-
(2013)
Nat Commun
, vol.4
, pp. 1528
-
-
Eissing, L.1
Scherer, T.2
Tödter, K.3
Knippschild, U.4
Greve, J.W.5
Buurman, W.A.6
Pinnschmidt, H.O.7
Rensen, S.S.8
Wolf, A.M.9
Bartelt, A.10
-
43
-
-
0033866432
-
Kupffer cell-derived prostaglandin E2 is involved in alcohol-induced fat accumulation in rat liver
-
Enomoto N, Ikejima K, Yamashina S, Enomoto A, Nishiura T, Nishimura T, Brenner DA, Schemmer P, Bradford BU, Rivera CA (2000) Kupffer cell-derived prostaglandin E2 is involved in alcohol-induced fat accumulation in rat liver. Am J Physiol Gastrointest Liver Physiol 279(1): G100-G106
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
, Issue.1
, pp. G100-G106
-
-
Enomoto, N.1
Ikejima, K.2
Yamashina, S.3
Enomoto, A.4
Nishiura, T.5
Nishimura, T.6
Brenner, D.A.7
Schemmer, P.8
Bradford, B.U.9
Rivera, C.A.10
-
44
-
-
84871709488
-
The role of the carbohydrate response element-binding protein in male fructosefed rats
-
Erion DM, Popov V, Hsiao JJ, Vatner D, Mitchell K, Yonemitsu S, Nagai Y, Kahn M, Gillum MP, Dong J (2012) The role of the carbohydrate response element-binding protein in male fructosefed rats. Endocrinology 154(1): 36-44
-
(2012)
Endocrinology
, vol.154
, Issue.1
, pp. 36-44
-
-
Erion, D.M.1
Popov, V.2
Hsiao, J.J.3
Vatner, D.4
Mitchell, K.5
Yonemitsu, S.6
Nagai, Y.7
Kahn, M.8
Gillum, M.P.9
Dong, J.10
-
45
-
-
1542615071
-
Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence
-
Ettinger SL, Sobel R, Whitmore TG, Akbari M, Bradley DR, Gleave ME, Nelson CC (2004) Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence. Cancer Res 64(6): 2212-2221
-
(2004)
Cancer Res
, vol.64
, Issue.6
, pp. 2212-2221
-
-
Ettinger, S.L.1
Sobel, R.2
Whitmore, T.G.3
Akbari, M.4
Bradley, D.R.5
Gleave, M.E.6
Nelson, C.C.7
-
46
-
-
79952529158
-
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
-
Feng D, Liu T, Sun Z, Bugge A, Mullican SE, Alenghat T, Liu XS, Lazar MA (2011) A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science 331(6022): 1315-1319
-
(2011)
Science
, vol.331
, Issue.6022
, pp. 1315-1319
-
-
Feng, D.1
Liu, T.2
Sun, Z.3
Bugge, A.4
Mullican, S.E.5
Alenghat, T.6
Liu, X.S.7
Lazar, M.A.8
-
47
-
-
77957302090
-
Hepatic steatosis: A role for de novo lipogenesis and the transcription factor SREBP-1c
-
Ferre P, Foufelle F (2010) Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c. Diabetes Obes Metab 12(s2): 83-92
-
(2010)
Diabetes Obes Metab
, vol.12
, Issue.s2
, pp. 83-92
-
-
Ferre, P.1
Foufelle, F.2
-
48
-
-
0029797027
-
Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver
-
Ferre T, Riu E, Bosch F, Valera A (1996) Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver. FASEB J 10(10): 1213-1218
-
(1996)
FASEB J
, vol.10
, Issue.10
, pp. 1213-1218
-
-
Ferre, T.1
Riu, E.2
Bosch, F.3
Valera, A.4
-
49
-
-
84876998618
-
Novel insights into ChREBP regulation and function
-
Filhoulaud G, Guilmeau S, Dentin R, Girard J, Postic C (2013) Novel insights into ChREBP regulation and function. Trends Endocrinol Metab 24(5): 257-268
-
(2013)
Trends Endocrinol Metab
, vol.24
, Issue.5
, pp. 257-268
-
-
Filhoulaud, G.1
Guilmeau, S.2
Dentin, R.3
Girard, J.4
Postic, C.5
-
50
-
-
84859157338
-
The degradation of apolipoprotein B100: Multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways
-
Fisher EA (2012) The degradation of apolipoprotein B100: multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways. Biochim Biophys Acta 1821(5): 778-781
-
(2012)
Biochim Biophys Acta
, vol.1821
, Issue.5
, pp. 778-781
-
-
Fisher, E.A.1
-
51
-
-
77953471622
-
Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice
-
Fritz V, Benfodda Z, Rodier G, Henriquet C, Iborra F, Avancès C, Allory Y, De La Taille A, Culine S, Blancou H (2010) Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice. Mol Cancer Ther 9(6): 1740-1754
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.6
, pp. 1740-1754
-
-
Fritz, V.1
Benfodda, Z.2
Rodier, G.3
Henriquet, C.4
Iborra, F.5
Avancès, C.6
Allory, Y.7
De La Taille, A.8
Culine, S.9
Blancou, H.10
-
52
-
-
73449089383
-
Coordinate regulation/localization of the carbohydrate responsive binding protein (ChREBP) by two nuclear export signal sites: Discovery of a new leucine-rich nuclear export signal site
-
Fukasawa M, Ge Q, Wynn RM, Ishii S, Uyeda K (2010) Coordinate regulation/localization of the carbohydrate responsive binding protein (ChREBP) by two nuclear export signal sites: discovery of a new leucine-rich nuclear export signal site. Biochem Biophys Res Commun 391(2): 1166-1169
-
(2010)
Biochem Biophys Res Commun
, vol.391
, Issue.2
, pp. 1166-1169
-
-
Fukasawa, M.1
Ge, Q.2
Wynn, R.M.3
Ishii, S.4
Uyeda, K.5
-
53
-
-
0037378516
-
Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors
-
Giandomenico V, Simonsson M, Grönroos E, Ericsson J (2003) Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors. Mol Cell Biol 23(7): 2587-2599
-
(2003)
Mol Cell Biol
, vol.23
, Issue.7
, pp. 2587-2599
-
-
Giandomenico, V.1
Simonsson, M.2
Grönroos, E.3
Ericsson, J.4
-
55
-
-
0030877118
-
Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes
-
Girard J, Ferré P, Foufelle F (1997) Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes. Annu Rev Nutr 17(1): 325-352
-
(1997)
Annu Rev Nutr
, vol.17
, Issue.1
, pp. 325-352
-
-
Girard, J.1
Ferré, P.2
Foufelle, F.3
-
57
-
-
12144286902
-
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
-
Graner E, Tang D, Rossi S, Baron A, Migita T, Weinstein LJ, Lechpammer M, Huesken D, Zimmermann J, Signoretti S (2004) The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer. Cancer Cell 5(3): 253-261
-
(2004)
Cancer Cell
, vol.5
, Issue.3
, pp. 253-261
-
-
Graner, E.1
Tang, D.2
Rossi, S.3
Baron, A.4
Migita, T.5
Weinstein, L.J.6
Lechpammer, M.7
Huesken, D.8
Zimmermann, J.9
Signoretti, S.10
-
59
-
-
84984953610
-
Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth
-
Griffiths B, Lewis CA, Bensaad K, Ros S, Zhang Q, Ferber EC, Konisti S, Peck B, Miess H, East P (2013) Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth. Cancer Metab 1(3)
-
(2013)
Cancer Metab
, vol.1
, Issue.3
-
-
Griffiths, B.1
Lewis, C.A.2
Bensaad, K.3
Ros, S.4
Zhang, Q.5
Ferber, E.C.6
Konisti, S.7
Peck, B.8
Miess, H.9
East, P.10
-
60
-
-
66149102890
-
The role of FOXO in the regulation of metabolism
-
Gross DN, Wan M, Birnbaum MJ (2009) The role of FOXO in the regulation of metabolism. Curr Diab Rep 9(3): 208-214
-
(2009)
Curr Diab Rep
, vol.9
, Issue.3
, pp. 208-214
-
-
Gross, D.N.1
Wan, M.2
Birnbaum, M.J.3
-
61
-
-
0025345278
-
Search for mediators of the lipogenic effects of tumor necrosis factor: Potential role for interleukin 6
-
Grunfeld C, Adi S, Soued M, Moser A, Fiers W, Feingold KR (1990) Search for mediators of the lipogenic effects of tumor necrosis factor: potential role for interleukin 6. Cancer Res 50(14): 4233-4238
-
(1990)
Cancer Res
, vol.50
, Issue.14
, pp. 4233-4238
-
-
Grunfeld, C.1
Adi, S.2
Soued, M.3
Moser, A.4
Fiers, W.5
Feingold, K.R.6
-
62
-
-
79959473762
-
O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver
-
Guinez C, Filhoulaud G, Rayah-Benhamed F, Marmier S, Dubuquoy C, Dentin R, Moldes M, Burnol A-F, Yang X, Lefebvre T (2011) O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver. Diabetes 60(5): 1399-1413
-
(2011)
Diabetes
, vol.60
, Issue.5
, pp. 1399-1413
-
-
Guinez, C.1
Filhoulaud, G.2
Rayah-Benhamed, F.3
Marmier, S.4
Dubuquoy, C.5
Dentin, R.6
Moldes, M.7
Burnol, A.-F.8
Yang, X.9
Lefebvre, T.10
-
63
-
-
77649216053
-
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to anti-lipogenic therapy
-
Guo D, Prins RM, Dang J, Kuga D, Iwanami A, Soto H, Lin KY, Huang TT, Akhavan D, Hock MB (2009) EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to anti-lipogenic therapy. Sci Signal 2(101): ra82
-
(2009)
Sci Signal
, vol.2
, Issue.101
-
-
Guo, D.1
Prins, R.M.2
Dang, J.3
Kuga, D.4
Iwanami, A.5
Soto, H.6
Lin, K.Y.7
Huang, T.T.8
Akhavan, D.9
Hock, M.B.10
-
64
-
-
0029961359
-
Cloning of human acetyl-CoA carboxylasebeta and its unique features
-
Ha J, Lee J-K, Kim K-S, Witters LA, Kim K-H (1996) Cloning of human acetyl-CoA carboxylasebeta and its unique features. Proc Natl Acad Sci U S A 93(21): 11466-11470
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.21
, pp. 11466-11470
-
-
Ha, J.1
Lee, J.-K.2
Kim, K.-S.3
Witters, L.A.4
Kim, K.-H.5
-
65
-
-
33847232207
-
Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice
-
Harada N, Oda Z, Hara Y, Fujinami K, Okawa M, Ohbuchi K, Yonemoto M, Ikeda Y, Ohwaki K, Aragane K (2007) Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice. Mol Cell Biol 27(5): 1881-1888
-
(2007)
Mol Cell Biol
, vol.27
, Issue.5
, pp. 1881-1888
-
-
Harada, N.1
Oda, Z.2
Hara, Y.3
Fujinami, K.4
Okawa, M.5
Ohbuchi, K.6
Yonemoto, M.7
Ikeda, Y.8
Ohwaki, K.9
Aragane, K.10
-
66
-
-
84858782079
-
AMPK: A nutrient and energy sensor that maintains energy homeostasis
-
Hardie DG, Ross FA, Hawley SA (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 13(4): 251-262
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, Issue.4
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
67
-
-
0031022573
-
Expression of human hepatic glucokinase in transgenic mice liver results in decreased glucose levels and reduced body weight
-
Hariharan N, Farrelly D, Hagan D, Hillyer D, Arbeeny C, Sabrah T, Treloar A, Brown K, Kalinowski S, Mookhtiar K (1997) Expression of human hepatic glucokinase in transgenic mice liver results in decreased glucose levels and reduced body weight. Diabetes 46(1): 11-16
-
(1997)
Diabetes
, vol.46
, Issue.1
, pp. 11-16
-
-
Hariharan, N.1
Farrelly, D.2
Hagan, D.3
Hillyer, D.4
Arbeeny, C.5
Sabrah, T.6
Treloar, A.7
Brown, K.8
Kalinowski, S.9
Mookhtiar, K.10
-
68
-
-
26644441651
-
ATP citrate lyase inhibition can suppress tumor cell growth
-
Hatzivassiliou G, Zhao F, Bauer DE, Andreadis C, Shaw AN, Dhanak D, Hingorani SR, Tuveson DA, Thompson CB (2005) ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell 8(4): 311-321
-
(2005)
Cancer Cell
, vol.8
, Issue.4
, pp. 311-321
-
-
Hatzivassiliou, G.1
Zhao, F.2
Bauer, D.E.3
Andreadis, C.4
Shaw, A.N.5
Dhanak, D.6
Hingorani, S.R.7
Tuveson, D.A.8
Thompson, C.B.9
-
69
-
-
84865196738
-
Glucose sensing by ChREBP/MondoA-Mlx transcription factors
-
Havula E, Hietakangas V (2012) Glucose sensing by ChREBP/MondoA-Mlx transcription factors. Semin Cell Dev Biol 23(6): 640-647
-
(2012)
Semin Cell Dev Biol
, vol.23
, Issue.6
, pp. 640-647
-
-
Havula, E.1
Hietakangas, V.2
-
70
-
-
14144251157
-
Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element binding protein-1c
-
Hegarty BD, Bobard A, Hainault I, Ferré P, Bossard P, Foufelle F (2005) Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element binding protein-1c. Proc Natl Acad Sci U S A 102(3): 791-796
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.3
, pp. 791-796
-
-
Hegarty, B.D.1
Bobard, A.2
Hainault, I.3
Ferré, P.4
Bossard, P.5
Foufelle, F.6
-
72
-
-
0016726198
-
Fatty acid synthesis in liver and adipose tissue of normal and genetically obese (ob/ob) mice during the 24-hour cycle
-
Hems DA, Rath EA, Verrinder TR (1975) Fatty acid synthesis in liver and adipose tissue of normal and genetically obese (ob/ob) mice during the 24-hour cycle. Biochem J 150: 167-173
-
(1975)
Biochem J
, vol.150
, pp. 167-173
-
-
Hems, D.A.1
Rath, E.A.2
Verrinder, T.R.3
-
73
-
-
84859921736
-
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
-
Herman MA, Peroni OD, Villoria J, Schön MR, Abumrad NA, Blüher M, Klein S, Kahn BB (2012) A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature 484(7394): 333-338
-
(2012)
Nature
, vol.484
, Issue.7394
, pp. 333-338
-
-
Herman, M.A.1
Peroni, O.D.2
Villoria, J.3
Schön, M.R.4
Abumrad, N.A.5
Blüher, M.6
Klein, S.7
Kahn, B.B.8
-
74
-
-
0035965231
-
Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway
-
Hirano Y, Yoshida M, Shimizu M, Sato R (2001) Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway. J Biol Chem 276(39): 36431-36437
-
(2001)
J Biol Chem
, vol.276
, Issue.39
, pp. 36431-36437
-
-
Hirano, Y.1
Yoshida, M.2
Shimizu, M.3
Sato, R.4
-
75
-
-
84867235842
-
Stearoyl-CoA desaturase: Rogue or innocent bystander?
-
Hodson L, Fielding BA (2013) Stearoyl-CoA desaturase: rogue or innocent bystander? Prog Lipid Res 52(1): 15-42
-
(2013)
Prog Lipid Res
, vol.52
, Issue.1
, pp. 15-42
-
-
Hodson, L.1
Fielding, B.A.2
-
76
-
-
0032568557
-
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
-
Horton JD, Bashmakov Y, Shimomura I, Shimano H (1998) Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc Natl Acad Sci U S A 95(11): 5987-5992
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.11
, pp. 5987-5992
-
-
Horton, J.D.1
Bashmakov, Y.2
Shimomura, I.3
Shimano, H.4
-
77
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton JD, Goldstein JL, Brown MS (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109(9): 1125-1131
-
(2002)
J Clin Invest
, vol.109
, Issue.9
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
79
-
-
59749091850
-
A complex interplay between Akt, TSC2, and the two mTOR complexes
-
Huang J, Manning BD (2009) A complex interplay between Akt, TSC2, and the two mTOR complexes. Biochem Soc Trans 37(Pt 1): 217
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 217
-
-
Huang, J.1
Manning, B.D.2
-
80
-
-
0031955070
-
Human fatty acid synthesis is reduced after the substitution of dietary starch for sugar
-
Hudgins LC, Seidman CE, Diakun J, Hirsch J (1998) Human fatty acid synthesis is reduced after the substitution of dietary starch for sugar. Am J Clin Nutr 67(4): 631-639
-
(1998)
Am J Clin Nutr
, vol.67
, Issue.4
, pp. 631-639
-
-
Hudgins, L.C.1
Seidman, C.E.2
Diakun, J.3
Hirsch, J.4
-
81
-
-
84867290287
-
Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation
-
Ido-Kitamura Y, Sasaki T, Kobayashi M, Kim H-J, Lee Y-S, Kikuchi O, Yokota-Hashimoto H, Iizuka K, Accili D, Kitamura T (2012) Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation. PLoS One 7(10): e47231
-
(2012)
PLoS One
, vol.7
, Issue.10
-
-
Ido-Kitamura, Y.1
Sasaki, T.2
Kobayashi, M.3
Kim, H.-J.4
Lee, Y.-S.5
Kikuchi, O.6
Yokota-Hashimoto, H.7
Iizuka, K.8
Accili, D.9
Kitamura, T.10
-
82
-
-
2442435802
-
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
-
Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K (2004) Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis. Proc Natl Acad Sci U S A 101(19): 7281-7286
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.19
, pp. 7281-7286
-
-
Iizuka, K.1
Bruick, R.K.2
Liang, G.3
Horton, J.D.4
Uyeda, K.5
-
83
-
-
33745896223
-
Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice
-
Iizuka K, Miller B, Uyeda K (2006) Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice. Am J Physiol Endocrinol Metab 291(2): E358-E364
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
, Issue.2
, pp. E358-E364
-
-
Iizuka, K.1
Miller, B.2
Uyeda, K.3
-
84
-
-
33646018341
-
Fatty acid elongases in mammals: Their regulation and roles in metabolism
-
Jakobsson A, Westerberg R, Jacobsson A (2006) Fatty acid elongases in mammals: their regulation and roles in metabolism. Prog Lipid Res 45(3): 237-249
-
(2006)
Prog Lipid Res
, vol.45
, Issue.3
, pp. 237-249
-
-
Jakobsson, A.1
Westerberg, R.2
Jacobsson, A.3
-
85
-
-
0038561165
-
Xylulose 5-phosphate mediates glucose- induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver
-
Kabashima T, Kawaguchi T, Wadzinski BE, Uyeda K (2003) Xylulose 5-phosphate mediates glucose- induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver. Proc Natl Acad Sci U S A 100(9): 5107-5112
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.9
, pp. 5107-5112
-
-
Kabashima, T.1
Kawaguchi, T.2
Wadzinski, B.E.3
Uyeda, K.4
-
86
-
-
66449137379
-
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
-
Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F (2009) GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice. J Clin Invest 119(5): 1201-1215
-
(2009)
J Clin Invest
, vol.119
, Issue.5
, pp. 1201-1215
-
-
Kammoun, H.L.1
Chabanon, H.2
Hainault, I.3
Luquet, S.4
Magnan, C.5
Koike, T.6
Ferré, P.7
Foufelle, F.8
-
87
-
-
0035923516
-
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein
-
Kawaguchi T, Takenoshita M, Kabashima T, Uyeda K (2001) Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein. Proc Natl Acad Sci U S A 98(24): 13710-13715
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.24
, pp. 13710-13715
-
-
Kawaguchi, T.1
Takenoshita, M.2
Kabashima, T.3
Uyeda, K.4
-
88
-
-
0037040185
-
Mechanism for fatty acid "sparing" effect on glucose-induced transcription regulation of carbohydrate-responsive element- binding protein by AMP-activated protein kinase
-
Kawaguchi T, Osatomi K, Yamashita H, Kabashima T, Uyeda K (2002) Mechanism for fatty acid "sparing" effect on glucose-induced transcription regulation of carbohydrate-responsive element- binding protein by AMP-activated protein kinase. J Biol Chem 277(6): 3829-3835
-
(2002)
J Biol Chem
, vol.277
, Issue.6
, pp. 3829-3835
-
-
Kawaguchi, T.1
Osatomi, K.2
Yamashita, H.3
Kabashima, T.4
Uyeda, K.5
-
89
-
-
0035038782
-
Mechanisms of nutritional and hormonal regulation of lipogenesis
-
Kersten S (2001) Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Rep 2(4): 282-286
-
(2001)
EMBO Rep
, vol.2
, Issue.4
, pp. 282-286
-
-
Kersten, S.1
-
90
-
-
0034713444
-
Roles of PPARs in health and disease
-
Kersten S, Desvergne B, Wahli W (2000) Roles of PPARs in health and disease. Nature 405(6785): 421-424
-
(2000)
Nature
, vol.405
, Issue.6785
, pp. 421-424
-
-
Kersten, S.1
Desvergne, B.2
Wahli, W.3
-
91
-
-
10644281006
-
Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c
-
Kim KH, Song MJ, Yoo EJ, Choe SS, Dai Park S, Kim JB (2004) Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c. J Biol Chem 279(50): 51999-52006
-
(2004)
J Biol Chem
, vol.279
, Issue.50
, pp. 51999-52006
-
-
Kim, K.H.1
Song, M.J.2
Yoo, E.J.3
Choe, S.S.4
Dai Park, S.5
Kim, J.B.6
-
92
-
-
77956315551
-
Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis
-
Kim H-S, Xiao C, Wang R-H, Lahusen T, Xu X, Vassilopoulos A, Vazquez-Ortiz G, Jeong W-I, Park O, Ki SH (2010) Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis. Cell Metab 12(3): 224-236
-
(2010)
Cell Metab
, vol.12
, Issue.3
, pp. 224-236
-
-
Kim, H.-S.1
Xiao, C.2
Wang, R.-H.3
Lahusen, T.4
Xu, X.5
Vassilopoulos, A.6
Vazquez-Ortiz, G.7
Jeong, W.-I.8
Park, O.9
Ki, S.H.10
-
93
-
-
41949120723
-
Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks
-
Knutson SK, Chyla BJ, Amann JM, Bhaskara S, Huppert SS, Hiebert SW (2008) Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks. EMBO J 27(7): 1017-1028
-
(2008)
EMBO J
, vol.27
, Issue.7
, pp. 1017-1028
-
-
Knutson, S.K.1
Chyla, B.J.2
Amann, J.M.3
Bhaskara, S.4
Huppert, S.S.5
Hiebert, S.W.6
-
94
-
-
42749092583
-
Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver
-
Koo H-Y, Wallig MA, Chung BH, Nara TY, Cho B, Nakamura MT (2008) Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver. Biochim Biophys Acta 1782(5): 341-348
-
(2008)
Biochim Biophys Acta
, vol.1782
, Issue.5
, pp. 341-348
-
-
Koo, H.-Y.1
Wallig, M.A.2
Chung, B.H.3
Nara, T.Y.4
Cho, B.5
Nakamura, M.T.6
-
95
-
-
77952552642
-
The Akt-SREBP nexus: Cell signaling meets lipid metabolism
-
Krycer JR, Sharpe LJ, Luu W, Brown AJ (2010) The Akt-SREBP nexus: cell signaling meets lipid metabolism. Trends Endocrinol Metab 21(5): 268-276
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.5
, pp. 268-276
-
-
Krycer, J.R.1
Sharpe, L.J.2
Luu, W.3
Brown, A.J.4
-
96
-
-
70349764508
-
REV-ERBα participates in circadian SREBP signaling and bile acid homeostasis
-
Le Martelot G, Claudel T, Gatfield D, Schaad O, Kornmann B, Sasso GL, Moschetta A, Schibler U (2009) REV-ERBα participates in circadian SREBP signaling and bile acid homeostasis. PLoS Biol 7(9): e1000181
-
(2009)
PLoS Biol
, vol.7
, Issue.9
-
-
Le Martelot, G.1
Claudel, T.2
Gatfield, D.3
Schaad, O.4
Kornmann, B.5
Sasso, G.L.6
Moschetta, A.7
Schibler, U.8
-
97
-
-
70350417158
-
Akt2 is required for hepatic lipid accumulation in models of insulin resistance
-
Leavens KF, Easton RM, Shulman GI, Previs SF, Birnbaum MJ (2009) Akt2 is required for hepatic lipid accumulation in models of insulin resistance. Cell Metab 10(5): 405-418
-
(2009)
Cell Metab
, vol.10
, Issue.5
, pp. 405-418
-
-
Leavens, K.F.1
Easton, R.M.2
Shulman, G.I.3
Previs, S.F.4
Birnbaum, M.J.5
-
98
-
-
45849137877
-
Regulation of hepatic lipogenesis by the transcription factor XBP1
-
Lee A-H, Scapa EF, Cohen DE, Glimcher LH (2008) Regulation of hepatic lipogenesis by the transcription factor XBP1. Science 320(5882): 1492-1496
-
(2008)
Science
, vol.320
, Issue.5882
, pp. 1492-1496
-
-
Lee, A.-H.1
Scapa, E.F.2
Cohen, D.E.3
Glimcher, L.H.4
-
99
-
-
0036217052
-
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
-
Lewis GF, Carpentier A, Adeli K, Giacca A (2002) Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 23(2): 201-229
-
(2002)
Endocr Rev
, vol.23
, Issue.2
, pp. 201-229
-
-
Lewis, G.F.1
Carpentier, A.2
Adeli, K.3
Giacca, A.4
-
100
-
-
33745297834
-
Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module
-
Li MV, Chang B, Imamura M, Poungvarin N, Chan L (2006) Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module. Diabetes 55(5): 1179-1189
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1179-1189
-
-
Li, M.V.1
Chang, B.2
Imamura, M.3
Poungvarin, N.4
Chan, L.5
-
101
-
-
34948883324
-
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
-
Li X, Zhang S, Blander G, Jeanette GT, Krieger M, Guarente L (2007) SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell 28(1): 91-106
-
(2007)
Mol Cell
, vol.28
, Issue.1
, pp. 91-106
-
-
Li, X.1
Zhang, S.2
Blander, G.3
Jeanette, G.T.4
Krieger, M.5
Guarente, L.6
-
102
-
-
77649264504
-
Bifurcation of insulin signaling pathway in rat liver: MTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis
-
Li S, Brown MS, Goldstein JL (2010) Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis. Proc Natl Acad Sci U S A 107(8): 3441-3446
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.8
, pp. 3441-3446
-
-
Li, S.1
Brown, M.S.2
Goldstein, J.L.3
-
103
-
-
79953755370
-
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice
-
Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, Jiang B, Park O, Luo Z, Lefai E, Shyy JY-J (2011) AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice. Cell Metab 13(4): 376-388
-
(2011)
Cell Metab
, vol.13
, Issue.4
, pp. 376-388
-
-
Li, Y.1
Xu, S.2
Mihaylova, M.M.3
Zheng, B.4
Hou, X.5
Jiang, B.6
Park, O.7
Luo, Z.8
Lefai, E.9
Shyy, J.Y.-J.10
-
104
-
-
0037088683
-
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
-
Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS (2002) Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J Biol Chem 277(11): 9520-9528
-
(2002)
J Biol Chem
, vol.277
, Issue.11
, pp. 9520-9528
-
-
Liang, G.1
Yang, J.2
Horton, J.D.3
Hammer, R.E.4
Goldstein, J.L.5
Brown, M.S.6
-
105
-
-
0037453056
-
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
-
Listenberger LL, Han X, Lewis SE, Cases S, Farese RV, Ory DS, Schaffer JE (2003) Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci U S A 100(6): 3077-3082
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.6
, pp. 3077-3082
-
-
Listenberger, L.L.1
Han, X.2
Lewis, S.E.3
Cases, S.4
Farese, R.V.5
Ory, D.S.6
Schaffer, J.E.7
-
106
-
-
78650520909
-
Lipoexpediency: De novo lipogenesis as a metabolic signal transmitter
-
Lodhi IJ, Wei X, Semenkovich CF (2011) Lipoexpediency: de novo lipogenesis as a metabolic signal transmitter. Trends Endocrinol Metab 22(1): 1-8
-
(2011)
Trends Endocrinol Metab
, vol.22
, Issue.1
, pp. 1-8
-
-
Lodhi, I.J.1
Wei, X.2
Semenkovich, C.F.3
-
107
-
-
33845909566
-
Pharmacological inhibitors of fatty acid synthase (FASN)-catalyzed endogenous fatty acid biogenesis: A new family of anti-cancer agents?
-
Lupu R, Menendez JA (2006) Pharmacological inhibitors of fatty acid synthase (FASN)-catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents? Curr Pharm Biotechnol 7(6): 483-494
-
(2006)
Curr Pharm Biotechnol
, vol.7
, Issue.6
, pp. 483-494
-
-
Lupu, R.1
Menendez, J.A.2
-
108
-
-
15744376705
-
Direct role of ChREBP• Mlx in regulating hepatic glucoseresponsive genes
-
Ma L, Tsatsos NG, Towle HC (2005) Direct role of ChREBP• Mlx in regulating hepatic glucoseresponsive genes. J Biol Chem 280(12): 12019-12027
-
(2005)
J Biol Chem
, vol.280
, Issue.12
, pp. 12019-12027
-
-
Ma, L.1
Tsatsos, N.G.2
Towle, H.C.3
-
109
-
-
33749407193
-
ChREBP* Mlx is the principal mediator of glucose-induced gene expression in the liver
-
Ma L, Robinson LN, Towle HC (2006) ChREBP* Mlx is the principal mediator of glucose-induced gene expression in the liver. J Biol Chem 281(39): 28721-28730
-
(2006)
J Biol Chem
, vol.281
, Issue.39
, pp. 28721-28730
-
-
Ma, L.1
Robinson, L.N.2
Towle, H.C.3
-
110
-
-
33846685948
-
A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription
-
Ma L, Sham YY, Walters KJ, Towle HC (2007) A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription. Nucleic Acids Res 35(1): 35-44
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.1
, pp. 35-44
-
-
Ma, L.1
Sham, Y.Y.2
Walters, K.J.3
Towle, H.C.4
-
112
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning BD, Cantley LC (2007) AKT/PKB signaling: navigating downstream. Cell 129(7): 1261-1274
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
113
-
-
33744781581
-
Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis
-
Mao J, DeMayo FJ, Li H, Abu-Elheiga L, Gu Z, Shaikenov TE, Kordari P, Chirala SS, Heird WC, Wakil SJ (2006) Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. Proc Natl Acad Sci U S A 103(22): 8552-8557
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.22
, pp. 8552-8557
-
-
Mao, J.1
DeMayo, F.J.2
Li, H.3
Abu-Elheiga, L.4
Gu, Z.5
Shaikenov, T.E.6
Kordari, P.7
Chirala, S.S.8
Heird, W.C.9
Wakil, S.J.10
-
114
-
-
51749095471
-
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression
-
Mao J-H, Kim I-J, Wu D, Climent J, Kang HC, DelRosario R, Balmain A (2008) FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. Science 321(5895): 1499-1502
-
(2008)
Science
, vol.321
, Issue.5895
, pp. 1499-1502
-
-
Mao, J.-H.1
Kim, I.-J.2
Wu, D.3
Climent, J.4
Kang, H.C.5
DelRosario, R.6
Balmain, A.7
-
115
-
-
0033231294
-
Association of nonalcoholic fatty liver disease with insulin resistance
-
Marchesini G, Brizi M, Morselli-Labate AM, Bianchi G, Bugianesi E, McCullough AJ, Forlani G, Melchionda N (1999) Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 107(5): 450-455
-
(1999)
Am J Med
, vol.107
, Issue.5
, pp. 450-455
-
-
Marchesini, G.1
Brizi, M.2
Morselli-Labate, A.M.3
Bianchi, G.4
Bugianesi, E.5
McCullough, A.J.6
Forlani, G.7
Melchionda, N.8
-
116
-
-
0037373008
-
Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
-
Matsusue K, Haluzik M, Lambert G, Yim S-H, Gavrilova O, Ward JM, Brewer B Jr, Reitman ML, Gonzalez FJ (2003) Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. J Clin Invest 111(5): 737
-
(2003)
J Clin Invest
, vol.111
, Issue.5
, pp. 737
-
-
Matsusue, K.1
Haluzik, M.2
Lambert, G.3
Yim, S.-H.4
Gavrilova, O.5
Ward, J.M.6
Brewer Jr, B.7
Reitman, M.L.8
Gonzalez, F.J.9
-
117
-
-
34948904815
-
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
-
Matsuzaka T, Shimano H, Yahagi N, Kato T, Atsumi A, Yamamoto T, Inoue N, Ishikawa M, Okada S, Ishigaki N (2007) Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. Nat Med 13(10): 1193-1202
-
(2007)
Nat Med
, vol.13
, Issue.10
, pp. 1193-1202
-
-
Matsuzaka, T.1
Shimano, H.2
Yahagi, N.3
Kato, T.4
Atsumi, A.5
Yamamoto, T.6
Inoue, N.7
Ishikawa, M.8
Okada, S.9
Ishigaki, N.10
-
118
-
-
84870541988
-
Elovl6 promotes nonalcoholic steatohepatitis
-
Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M, Nakagawa Y, Ishii K, Shimada M (2012) Elovl6 promotes nonalcoholic steatohepatitis. Hepatology 56(6): 2199-2208
-
(2012)
Hepatology
, vol.56
, Issue.6
, pp. 2199-2208
-
-
Matsuzaka, T.1
Atsumi, A.2
Matsumori, R.3
Nie, T.4
Shinozaki, H.5
Suzuki-Kemuriyama, N.6
Kuba, M.7
Nakagawa, Y.8
Ishii, K.9
Shimada, M.10
-
119
-
-
0012249041
-
Metabolism of neoplastic tissue. IV. A study of lipid synthesis in neoplastic tissue slices in vitro
-
Medes G, Thomas A, Weinhouse S (1953) Metabolism of neoplastic tissue. IV. A study of lipid synthesis in neoplastic tissue slices in vitro. Cancer Res 13(1): 27-29
-
(1953)
Cancer Res
, vol.13
, Issue.1
, pp. 27-29
-
-
Medes, G.1
Thomas, A.2
Weinhouse, S.3
-
120
-
-
3543150636
-
The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3
-
Merla G, Howald C, Antonarakis SE, Reymond A (2004) The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3. Hum Mol Genet 13(14): 1505-1514
-
(2004)
Hum Mol Genet
, vol.13
, Issue.14
, pp. 1505-1514
-
-
Merla, G.1
Howald, C.2
Antonarakis, S.E.3
Reymond, A.4
-
121
-
-
0034612590
-
Mlx, a new Maxlike bHLHZip family member: The center stage of a novel transcription factors regulatory pathway?
-
Meroni G, Cairo S, Merla G, Messali S, Brent R, Ballabio A, Reymond A (2000) Mlx, a new Maxlike bHLHZip family member: the center stage of a novel transcription factors regulatory pathway? Oncogene 19(29): 3266-3277
-
(2000)
Oncogene
, vol.19
, Issue.29
, pp. 3266-3277
-
-
Meroni, G.1
Cairo, S.2
Merla, G.3
Messali, S.4
Brent, R.5
Ballabio, A.6
Reymond, A.7
-
122
-
-
54249161009
-
ATP citrate lyase: Activation and therapeutic implications in nonsmall cell lung cancer
-
Migita T, Narita T, Nomura K, Miyagi E, Inazuka F, Matsuura M, Ushijima M, Mashima T, Seimiya H, Satoh Y (2008) ATP citrate lyase: activation and therapeutic implications in nonsmall cell lung cancer. Cancer Res 68(20): 8547-8554
-
(2008)
Cancer Res
, vol.68
, Issue.20
, pp. 8547-8554
-
-
Migita, T.1
Narita, T.2
Nomura, K.3
Miyagi, E.4
Inazuka, F.5
Matsuura, M.6
Ushijima, M.7
Mashima, T.8
Seimiya, H.9
Satoh, Y.10
-
123
-
-
36448991861
-
Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis
-
Miyazaki M, Flowers MT, Sampath H, Chu K, Otzelberger C, Liu X, Ntambi JM (2007) Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab 6(6): 484-496
-
(2007)
Cell Metab
, vol.6
, Issue.6
, pp. 484-496
-
-
Miyazaki, M.1
Flowers, M.T.2
Sampath, H.3
Chu, K.4
Otzelberger, C.5
Liu, X.6
Ntambi, J.M.7
-
124
-
-
34347235098
-
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
-
Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV (2007) Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab 6(1): 69-78
-
(2007)
Cell Metab
, vol.6
, Issue.1
, pp. 69-78
-
-
Monetti, M.1
Levin, M.C.2
Watt, M.J.3
Sajan, M.P.4
Marmor, S.5
Hubbard, B.K.6
Stevens, R.D.7
Bain, J.R.8
Newgard, C.B.9
Farese, R.V.10
-
125
-
-
0035977004
-
Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins
-
Moon Y-A, Shah NA, Mohapatra S, Warrington JA, Horton JD (2001) Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins. J Biol Chem 276(48): 45358-45366
-
(2001)
J Biol Chem
, vol.276
, Issue.48
, pp. 45358-45366
-
-
Moon, Y.-A.1
Shah, N.A.2
Mohapatra, S.3
Warrington, J.A.4
Horton, J.D.5
-
126
-
-
80051706346
-
Role for PPARγ in obesityinduced hepatic steatosis as determined by hepatocyte-and macrophage-specific conditional knockouts
-
Morán-Salvador E, López-Parra M, García-Alonso V, Titos E, Martínez-Clemente M, González-Périz A, López-Vicario C, Barak Y, Arroyo V, Clària J (2011) Role for PPARγ in obesityinduced hepatic steatosis as determined by hepatocyte-and macrophage-specific conditional knockouts. FASEB J 25(8): 2538-2550
-
(2011)
FASEB J
, vol.25
, Issue.8
, pp. 2538-2550
-
-
Morán-Salvador, E.1
López-Parra, M.2
García-Alonso, V.3
Titos, E.4
Martínez-Clemente, M.5
González-Périz, A.6
López-Vicario, C.7
Barak, Y.8
Arroyo, V.9
Clària, J.10
-
127
-
-
0023789884
-
Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase
-
Munday MR, Campbell DG, Carling D, Hardie DG (1988) Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase. Eur J Biochem 175(2): 331-338
-
(1988)
Eur J Biochem
, vol.175
, Issue.2
, pp. 331-338
-
-
Munday, M.R.1
Campbell, D.G.2
Carling, D.3
Hardie, D.G.4
-
128
-
-
33646345376
-
Ubiquitin ligases: Cell-cycle control and cancer
-
Nakayama KI, Nakayama K (2006) Ubiquitin ligases: cell-cycle control and cancer. Nat Rev Cancer 6(5): 369-381
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.5
, pp. 369-381
-
-
Nakayama, K.I.1
Nakayama, K.2
-
129
-
-
4644249187
-
Kupffer cell-derived prostaglandin E2 is involved in regulation of lipid synthesis in rat liver tissue
-
Neyrinck AM, Margagliotti S, Gomez C, Delzenne NM (2004) Kupffer cell-derived prostaglandin E2 is involved in regulation of lipid synthesis in rat liver tissue. Cell Biochem Funct 22(5): 327-332
-
(2004)
Cell Biochem Funct
, vol.22
, Issue.5
, pp. 327-332
-
-
Neyrinck, A.M.1
Margagliotti, S.2
Gomez, C.3
Delzenne, N.M.4
-
130
-
-
0034672690
-
From cholesterol transport to signal transduction: Low density lipoprotein receptor, very low density lipoprotein receptor, and apolipoprotein E receptor-2
-
Nimpf J, Schneider WJ (2000) From cholesterol transport to signal transduction: low density lipoprotein receptor, very low density lipoprotein receptor, and apolipoprotein E receptor-2. Biochim Biophys Acta 1529(1): 287-298
-
(2000)
Biochim Biophys Acta
, vol.1529
, Issue.1
, pp. 287-298
-
-
Nimpf, J.1
Schneider, W.J.2
-
131
-
-
0030884675
-
Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism
-
Niswender KD, Shiota M, Postic C, Cherrington AD, Magnuson MA (1997) Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism. J Biol Chem 272(36): 22570-22575
-
(1997)
J Biol Chem
, vol.272
, Issue.36
, pp. 22570-22575
-
-
Niswender, K.D.1
Shiota, M.2
Postic, C.3
Cherrington, A.D.4
Magnuson, M.A.5
-
132
-
-
84856756928
-
The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease
-
Nomura K, Yamanouchi T (2012) The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease. J Nutr Biochem 23(3): 203-208
-
(2012)
J Nutr Biochem
, vol.23
, Issue.3
, pp. 203-208
-
-
Nomura, K.1
Yamanouchi, T.2
-
133
-
-
0028929156
-
Interleukin-6 stimulates hepatic triglyceride secretion in rats
-
Nonogaki K, Fuller GM, Fuentes NL, Moser AH, Staprans I, Grunfeld C, Feingold KR (1995) Interleukin-6 stimulates hepatic triglyceride secretion in rats. Endocrinology 136(5): 2143-2149
-
(1995)
Endocrinology
, vol.136
, Issue.5
, pp. 2143-2149
-
-
Nonogaki, K.1
Fuller, G.M.2
Fuentes, N.L.3
Moser, A.H.4
Staprans, I.5
Grunfeld, C.6
Feingold, K.R.7
-
134
-
-
0037143752
-
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
-
Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD (2002) Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl Acad Sci U S A 99(17): 11482-11486
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.17
, pp. 11482-11486
-
-
Ntambi, J.M.1
Miyazaki, M.2
Stoehr, J.P.3
Lan, H.4
Kendziorski, C.M.5
Yandell, B.S.6
Song, Y.7
Cohen, P.8
Friedman, J.M.9
Attie, A.D.10
-
135
-
-
0033857387
-
Treatment of insulin resistance with peroxisome proliferator-activated receptor γ agonists
-
Olefsky JM (2000) Treatment of insulin resistance with peroxisome proliferator-activated receptor γ agonists. J Clin Invest 106(4): 467
-
(2000)
J Clin Invest
, vol.106
, Issue.4
, pp. 467
-
-
Olefsky, J.M.1
-
136
-
-
78650928027
-
Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver
-
Onoyama I, Suzuki A, Matsumoto A, Tomita K, Katagiri H, Oike Y, Nakayama K, Nakayama KI (2011) Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver. J Clin Invest 121(1): 342
-
(2011)
J Clin Invest
, vol.121
, Issue.1
, pp. 342
-
-
Onoyama, I.1
Suzuki, A.2
Matsumoto, A.3
Tomita, K.4
Katagiri, H.5
Oike, Y.6
Nakayama, K.7
Nakayama, K.I.8
-
137
-
-
84867067610
-
Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase
-
Owen JL, Zhang Y, Bae S-H, Farooqi MS, Liang G, Hammer RE, Goldstein JL, Brown MS (2012) Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase. Proc Natl Acad Sci U S A 109(40): 16184-16189
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.40
, pp. 16184-16189
-
-
Owen, J.L.1
Zhang, Y.2
Bae, S.-H.3
Farooqi, M.S.4
Liang, G.5
Hammer, R.E.6
Goldstein, J.L.7
Brown, M.S.8
-
138
-
-
0032726283
-
Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance
-
Parks EJ, Krauss RM, Christiansen MP, Neese RA, Hellerstein MK (1999) Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance. J Clin Invest 104(8): 1087-1096
-
(1999)
J Clin Invest
, vol.104
, Issue.8
, pp. 1087-1096
-
-
Parks, E.J.1
Krauss, R.M.2
Christiansen, M.P.3
Neese, R.A.4
Hellerstein, M.K.5
-
139
-
-
85008894724
-
Tissue specific induction of ChREBP isoforms in carbohydrate refed mice and their impact on lipogenesis (642.8)
-
Paton C, Stamatikos A, Rogowski M (2014) Tissue specific induction of ChREBP isoforms in carbohydrate refed mice and their impact on lipogenesis (642.8). FASEB J 28(1 Suppl): 642-648
-
(2014)
FASEB J
, vol.28
, Issue.1
, pp. 642-648
-
-
Paton, C.1
Stamatikos, A.2
Rogowski, M.3
-
140
-
-
0020773031
-
Fatty acid synthesis in liver and adipose tissue
-
Pearce J (1983) Fatty acid synthesis in liver and adipose tissue. Proc Nutr Soc 42(02): 263-271
-
(1983)
Proc Nutr Soc
, vol.42
, Issue.2
, pp. 263-271
-
-
Pearce, J.1
-
141
-
-
33645074450
-
Etiology of insulin resistance
-
Petersen KF, Shulman GI (2006) Etiology of insulin resistance. Am J Med 119(5): S10-S16
-
(2006)
Am J Med
, vol.119
, Issue.5
, pp. S10-S16
-
-
Petersen, K.F.1
Shulman, G.I.2
-
142
-
-
79961165137
-
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway
-
Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN (2011) mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell 146(3): 408-420
-
(2011)
Cell
, vol.146
, Issue.3
, pp. 408-420
-
-
Peterson, T.R.1
Sengupta, S.S.2
Harris, T.E.3
Carmack, A.E.4
Kang, S.A.5
Balderas, E.6
Guertin, D.A.7
Madden, K.L.8
Carpenter, A.E.9
Finck, B.N.10
-
143
-
-
77958595135
-
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism
-
Ponugoti B, Kim D-H, Xiao Z, Smith Z, Miao J, Zang M, Wu S-Y, Chiang C-M, Veenstra TD, Kemper JK (2010) SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism. J Biol Chem 285(44): 33959-33970
-
(2010)
J Biol Chem
, vol.285
, Issue.44
, pp. 33959-33970
-
-
Ponugoti, B.1
Kim, D.-H.2
Xiao, Z.3
Smith, Z.4
Miao, J.5
Zang, M.6
Wu, S.-Y.7
Chiang, C.-M.8
Veenstra, T.D.9
Kemper, J.K.10
-
144
-
-
50049116472
-
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
-
Porstmann T, Santos CR, Griffiths B, Cully M, Wu M, Leevers S, Griffiths JR, Chung Y-L, Schulze A (2008) SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth. Cell Metab 8(3): 224-236
-
(2008)
Cell Metab
, vol.8
, Issue.3
, pp. 224-236
-
-
Porstmann, T.1
Santos, C.R.2
Griffiths, B.3
Cully, M.4
Wu, M.5
Leevers, S.6
Griffiths, J.R.7
Chung, Y.-L.8
Schulze, A.9
-
145
-
-
40549135297
-
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
-
Postic C, Girard J (2008) Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest 118(3): 829
-
(2008)
J Clin Invest
, vol.118
, Issue.3
, pp. 829
-
-
Postic, C.1
Girard, J.2
-
146
-
-
38449087713
-
ChREBP, a transcriptional regulator of glucose and lipid metabolism
-
Postic C, Dentin R, Denechaud P-D, Girard J (2007) ChREBP, a transcriptional regulator of glucose and lipid metabolism. Annu Rev Nutr 27: 179-192
-
(2007)
Annu Rev Nutr
, vol.27
, pp. 179-192
-
-
Postic, C.1
Dentin, R.2
Denechaud, P.-D.3
Girard, J.4
-
147
-
-
33748751591
-
Phosphorylation and ubiquitination of the transcription factor sterol regulatory element-binding protein-1 in response to DNA binding
-
Punga T, Bengoechea-Alonso MT, Ericsson J (2006) Phosphorylation and ubiquitination of the transcription factor sterol regulatory element-binding protein-1 in response to DNA binding. J Biol Chem 281(35): 25278-25286
-
(2006)
J Biol Chem
, vol.281
, Issue.35
, pp. 25278-25286
-
-
Punga, T.1
Bengoechea-Alonso, M.T.2
Ericsson, J.3
-
148
-
-
63449112017
-
Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
-
Purushotham A, Schug TT, Xu Q, Surapureddi S, Guo X, Li X (2009) Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab 9(4): 327-338
-
(2009)
Cell Metab
, vol.9
, Issue.4
, pp. 327-338
-
-
Purushotham, A.1
Schug, T.T.2
Xu, Q.3
Surapureddi, S.4
Guo, X.5
Li, X.6
-
149
-
-
56449110891
-
Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: A delicate balance
-
Radhakrishnan A, Goldstein JL, McDonald JG, Brown MS (2008) Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance. Cell Metab 8(6): 512-521
-
(2008)
Cell Metab
, vol.8
, Issue.6
, pp. 512-521
-
-
Radhakrishnan, A.1
Goldstein, J.L.2
McDonald, J.G.3
Brown, M.S.4
-
150
-
-
0028068292
-
Peroxisomal lipid metabolism
-
Reddy JK, Mannaerts GP (1994) Peroxisomal lipid metabolism. Annu Rev Nutr 14(1): 343-370
-
(1994)
Annu Rev Nutr
, vol.14
, Issue.1
, pp. 343-370
-
-
Reddy, J.K.1
Mannaerts, G.P.2
-
151
-
-
33645828659
-
Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation
-
Reddy JK, Rao MS (2006) Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation. Am J Physiol Gastrointest Liver Physiol 290(5): G852-G858
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, Issue.5
, pp. G852-G858
-
-
Reddy, J.K.1
Rao, M.S.2
-
152
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ
-
Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro J-MA, Shimomura I, Shan B, Brown MS, Goldstein JL, Mangelsdorf DJ (2000) Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ. Genes Dev 14(22): 2819-2830
-
(2000)
Genes Dev
, vol.14
, Issue.22
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.-M.A.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
153
-
-
84890731711
-
Regulation of protein degradation by O-GlcNAcylation: Crosstalk with ubiquitination
-
Ruan H-B, Nie Y, Yang X (2013) Regulation of protein degradation by O-GlcNAcylation: crosstalk with ubiquitination. Mol Cell Proteomics 12(12): 3489-3497
-
(2013)
Mol Cell Proteomics
, vol.12
, Issue.12
, pp. 3489-3497
-
-
Ruan, H.-B.1
Nie, Y.2
Yang, X.3
-
154
-
-
14044264801
-
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis
-
Rudic RD, McNamara P, Curtis A-M, Boston RC, Panda S, Hogenesch JB, FitzGerald GA (2004) BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol 2(11): e377
-
(2004)
PLoS Biol
, vol.2
, Issue.11
-
-
Rudic, R.D.1
McNamara, P.2
Curtis, A.-M.3
Boston, R.C.4
Panda, S.5
Hogenesch, J.B.6
FitzGerald, G.A.7
-
155
-
-
0035877604
-
Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription
-
Rufo C, Teran-Garcia M, Nakamura MT, Koo S-H, Towle HC, Clarke SD (2001) Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription. J Biol Chem 276(24): 21969-21975
-
(2001)
J Biol Chem
, vol.276
, Issue.24
, pp. 21969-21975
-
-
Rufo, C.1
Teran-Garcia, M.2
Nakamura, M.T.3
Koo, S.-H.4
Towle, H.C.5
Clarke, S.D.6
-
156
-
-
78649443736
-
The role of O -linked GlcNAc modification on the glucose response of ChREBP
-
Sakiyama H, Fujiwara N, Noguchi T, Eguchi H, Yoshihara D, Uyeda K, Suzuki K (2010) The role of O -linked GlcNAc modification on the glucose response of ChREBP. Biochem Biophys Res Commun 402(4): 784-789
-
(2010)
Biochem Biophys Res Commun
, vol.402
, Issue.4
, pp. 784-789
-
-
Sakiyama, H.1
Fujiwara, N.2
Noguchi, T.3
Eguchi, H.4
Yoshihara, D.5
Uyeda, K.6
Suzuki, K.7
-
157
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414(6865): 799-806
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
158
-
-
84857861919
-
Mechanisms for insulin resistance: Common threads and missing links
-
Samuel VT, Shulman GI (2012) Mechanisms for insulin resistance: common threads and missing links. Cell 148(5): 852-871
-
(2012)
Cell
, vol.148
, Issue.5
, pp. 852-871
-
-
Samuel, V.T.1
Shulman, G.I.2
-
159
-
-
33644654777
-
Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2
-
Savage DB, Choi CS, Samuel VT, Liu Z-X, Zhang D, Wang A, Zhang X-M, Cline GW, Yu XX, Geisler JG (2006) Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. J Clin Invest 116(3): 817
-
(2006)
J Clin Invest
, vol.116
, Issue.3
, pp. 817
-
-
Savage, D.B.1
Choi, C.S.2
Samuel, V.T.3
Liu, Z.-X.4
Zhang, D.5
Wang, A.6
Zhang, X.-M.7
Cline, G.W.8
Yu, X.X.9
Geisler, J.G.10
-
161
-
-
0037216466
-
Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets
-
Schwarz J-M, Linfoot P, Dare D, Aghajanian K (2003) Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets. Am J Clin Nutr 77(1): 43-50
-
(2003)
Am J Clin Nutr
, vol.77
, Issue.1
, pp. 43-50
-
-
Schwarz, J.-M.1
Linfoot, P.2
Dare, D.3
Aghajanian, K.4
-
162
-
-
42149170517
-
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man
-
Scott E, Carter A, Grant P (2008) Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man. Int J Obes (Lond) 32(4): 658-662
-
(2008)
Int J Obes (Lond)
, vol.32
, Issue.4
, pp. 658-662
-
-
Scott, E.1
Carter, A.2
Grant, P.3
-
163
-
-
0035085155
-
Very-low-density lipoprotein assembly and secretion
-
Shelness GS, Sellers JA (2001) Very-low-density lipoprotein assembly and secretion. Curr Opin Lipidol 12(2): 151-157
-
(2001)
Curr Opin Lipidol
, vol.12
, Issue.2
, pp. 151-157
-
-
Shelness, G.S.1
Sellers, J.A.2
-
164
-
-
0029094172
-
Two CACGTG motifs with proper spacing dictate the carbohydrate regulation of hepatic gene transcription
-
Shih H-M, Liu Z, Towle HC (1995) Two CACGTG motifs with proper spacing dictate the carbohydrate regulation of hepatic gene transcription. J Biol Chem 270(37): 21991-21997
-
(1995)
J Biol Chem
, vol.270
, Issue.37
, pp. 21991-21997
-
-
Shih, H.-M.1
Liu, Z.2
Towle, H.C.3
-
165
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
-
Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL (1997) Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 99(5): 846
-
(1997)
J Clin Invest
, vol.99
, Issue.5
, pp. 846
-
-
Shimano, H.1
Horton, J.D.2
Shimomura, I.3
Hammer, R.E.4
Brown, M.S.5
Goldstein, J.L.6
-
166
-
-
80053054824
-
Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation
-
Shimba S, Ogawa T, Hitosugi S, Ichihashi Y, Nakadaira Y, Kobayashi M, Tezuka M, Kosuge Y, Ishige K, Ito Y (2011) Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation. PLoS One 6(9): e25231
-
(2011)
PLoS One
, vol.6
, Issue.9
-
-
Shimba, S.1
Ogawa, T.2
Hitosugi, S.3
Ichihashi, Y.4
Nakadaira, Y.5
Kobayashi, M.6
Tezuka, M.7
Kosuge, Y.8
Ishige, K.9
Ito, Y.10
-
167
-
-
0030961960
-
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
-
Shimomura I, Shimano H, Horton JD, Goldstein JL, Brown MS (1997) Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J Clin Invest 99(5): 838
-
(1997)
J Clin Invest
, vol.99
, Issue.5
, pp. 838
-
-
Shimomura, I.1
Shimano, H.2
Horton, J.D.3
Goldstein, J.L.4
Brown, M.S.5
-
168
-
-
0033598749
-
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes
-
Shimomura I, Bashmakov Y, Ikemoto S, Horton JD, Brown MS, Goldstein JL (1999) Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes. Proc Natl Acad Sci U S A 96(24): 13656-13661
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.24
, pp. 13656-13661
-
-
Shimomura, I.1
Bashmakov, Y.2
Ikemoto, S.3
Horton, J.D.4
Brown, M.S.5
Goldstein, J.L.6
-
169
-
-
0033636780
-
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
-
Shimomura I, Matsuda M, Hammer RE, Bashmakov Y, Brown MS, Goldstein JL (2000) Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell 6(1): 77-86
-
(2000)
Mol Cell
, vol.6
, Issue.1
, pp. 77-86
-
-
Shimomura, I.1
Matsuda, M.2
Hammer, R.E.3
Bashmakov, Y.4
Brown, M.S.5
Goldstein, J.L.6
-
170
-
-
0037411269
-
Structural and functional organization of the animal fatty acid synthase
-
Smith S, Witkowski A, Joshi AK (2003) Structural and functional organization of the animal fatty acid synthase. Prog Lipid Res 42(4): 289-317
-
(2003)
Prog Lipid Res
, vol.42
, Issue.4
, pp. 289-317
-
-
Smith, S.1
Witkowski, A.2
Joshi, A.K.3
-
171
-
-
0034083772
-
Insulin: Understanding its action in health and disease
-
Sonksen P, Sonksen J (2000) Insulin: understanding its action in health and disease. Br J Anaesth 85(1): 69-79
-
(2000)
Br J Anaesth
, vol.85
, Issue.1
, pp. 69-79
-
-
Sonksen, P.1
Sonksen, J.2
-
172
-
-
45749158901
-
Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity
-
Sookoian S, Gemma C, Gianotti TF, Burgueño A, Castaño G, Pirola CJ (2008) Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity. Am J Clin Nutr 87(6): 1606-1615
-
(2008)
Am J Clin Nutr
, vol.87
, Issue.6
, pp. 1606-1615
-
-
Sookoian, S.1
Gemma, C.2
Gianotti, T.F.3
Burgueño, A.4
Castaño, G.5
Pirola, C.J.6
-
173
-
-
84875210996
-
Circadian disruption leads to insulin resistance and obesity
-
Shi S-Q, Ansari TS, McGuinness OP, Wasserman DH, Johnson CH (2013) Circadian disruption leads to insulin resistance and obesity. Curr Biol 23(5): 372-381
-
(2013)
Curr Biol
, vol.23
, Issue.5
, pp. 372-381
-
-
Shi, S.-Q.1
Ansari, T.S.2
McGuinness, O.P.3
Wasserman, D.H.4
Johnson, C.H.5
-
174
-
-
2442614148
-
Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes
-
Stoeckman AK, Ma L, Towle HC (2004) Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes. J Biol Chem 279(15): 15662-15669
-
(2004)
J Biol Chem
, vol.279
, Issue.15
, pp. 15662-15669
-
-
Stoeckman, A.K.1
Ma, L.2
Towle, H.C.3
-
175
-
-
0016792915
-
Presence of two polypeptide chains comprising fatty acid synthetase
-
Stoops JK, Arslanian MJ, Oh YH, Aune KC, Vanaman TC, Wakil SJ (1975) Presence of two polypeptide chains comprising fatty acid synthetase. Proc Natl Acad Sci U S A 72(5): 1940-1944
-
(1975)
Proc Natl Acad Sci U S A
, vol.72
, Issue.5
, pp. 1940-1944
-
-
Stoops, J.K.1
Arslanian, M.J.2
Oh, Y.H.3
Aune, K.C.4
Vanaman, T.C.5
Wakil, S.J.6
-
176
-
-
77952863834
-
Genetic control of de novo lipogenesis: Role in diet-induced obesity
-
Strable MS, Ntambi JM (2010) Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit Rev Biochem Mol Biol 45(3): 199-214
-
(2010)
Crit Rev Biochem Mol Biol
, vol.45
, Issue.3
, pp. 199-214
-
-
Strable, M.S.1
Ntambi, J.M.2
-
177
-
-
84871655682
-
Dissociating fatty liver and diabetes
-
Sun Z, Lazar MA (2013) Dissociating fatty liver and diabetes. Trends Endocrinol Metab 24(1): 4-12
-
(2013)
Trends Endocrinol Metab
, vol.24
, Issue.1
, pp. 4-12
-
-
Sun, Z.1
Lazar, M.A.2
-
178
-
-
22544466429
-
Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro
-
Sun L-P, Li L, Goldstein JL, Brown MS (2005) Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro. J Biol Chem 280(28): 26483-26490
-
(2005)
J Biol Chem
, vol.280
, Issue.28
, pp. 26483-26490
-
-
Sun, L.-P.1
Li, L.2
Goldstein, J.L.3
Brown, M.S.4
-
179
-
-
34249861927
-
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins
-
Sun L-P, Seemann J, Goldstein JL, Brown MS (2007) Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins. Proc Natl Acad Sci U S A 104(16): 6519-6526
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.16
, pp. 6519-6526
-
-
Sun, L.-P.1
Seemann, J.2
Goldstein, J.L.3
Brown, M.S.4
-
180
-
-
23844530704
-
Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF Fbw7
-
Sundqvist A, Bengoechea-Alonso MT, Ye X, Lukiyanchuk V, Jin J, Harper JW, Ericsson J (2005) Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF Fbw7. Cell Metab 1(6): 379-391
-
(2005)
Cell Metab
, vol.1
, Issue.6
, pp. 379-391
-
-
Sundqvist, A.1
Bengoechea-Alonso, M.T.2
Ye, X.3
Lukiyanchuk, V.4
Jin, J.5
Harper, J.W.6
Ericsson, J.7
-
181
-
-
33746291023
-
Increased lipogenesis in cancer cells: New players, novel targets
-
Swinnen JV, Brusselmans K, Verhoeven G (2006) Increased lipogenesis in cancer cells: new players, novel targets. Curr Opin Clin Nutr Metab Care 9(4): 358-365
-
(2006)
Curr Opin Clin Nutr Metab Care
, vol.9
, Issue.4
, pp. 358-365
-
-
Swinnen, J.V.1
Brusselmans, K.2
Verhoeven, G.3
-
182
-
-
0025820815
-
Localization of the carbohydrate response element of the rat L-type pyruvate kinase gene
-
Thompson KS, Towle H (1991) Localization of the carbohydrate response element of the rat L-type pyruvate kinase gene. J Biol Chem 266(14): 8679-8682
-
(1991)
J Biol Chem
, vol.266
, Issue.14
, pp. 8679-8682
-
-
Thompson, K.S.1
Towle, H.2
-
183
-
-
0037155935
-
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
-
Tobin KAR, Ulven SM, Schuster GU, Steineger HH, Andresen SM, Gustafsson J-Å, Nebb HI (2002) Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis. J Biol Chem 277(12): 10691-10697
-
(2002)
J Biol Chem
, vol.277
, Issue.12
, pp. 10691-10697
-
-
Tobin, K.A.R.1
Ulven, S.M.2
Schuster, G.U.3
Steineger, H.H.4
Andresen, S.M.5
Gustafsson, J.6
Nebb, H.I.7
-
184
-
-
29644446917
-
Glucose activation of ChREBP in hepatocytes occurs via a two-step mechanism
-
Tsatsos NG, Towle HC (2006) Glucose activation of ChREBP in hepatocytes occurs via a two-step mechanism. Biochem Biophys Res Commun 340(2): 449-456
-
(2006)
Biochem Biophys Res Commun
, vol.340
, Issue.2
, pp. 449-456
-
-
Tsatsos, N.G.1
Towle, H.C.2
-
185
-
-
0029828779
-
Molecular cloning of cDNA encoding rat very long-chain acyl-CoA synthetase
-
Uchiyama A, Aoyama T, Kamijo K, Uchida Y, Kondo N, Orii T, Hashimoto T (1996) Molecular cloning of cDNA encoding rat very long-chain acyl-CoA synthetase. J Biol Chem 271(48): 30360-30365
-
(1996)
J Biol Chem
, vol.271
, Issue.48
, pp. 30360-30365
-
-
Uchiyama, A.1
Aoyama, T.2
Kamijo, K.3
Uchida, Y.4
Kondo, N.5
Orii, T.6
Hashimoto, T.7
-
186
-
-
4544220704
-
Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity
-
Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, Fumagalli S, Allegrini PR, Kozma SC, Auwerx J (2004) Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity. Nature 431(7005): 200-205
-
(2004)
Nature
, vol.431
, Issue.7005
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
Sticker, M.6
Fumagalli, S.7
Allegrini, P.R.8
Kozma, S.C.9
Auwerx, J.10
-
187
-
-
33745196745
-
Activation of AMP-activated protein kinase in the liver: A new strategy for the management of metabolic hepatic disorders
-
Viollet B, Foretz M, Guigas B, Horman S, Dentin R, Bertrand L, Hue L, Andreelli F (2006) Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders. J Physiol 574(1): 41-53
-
(2006)
J Physiol
, vol.574
, Issue.1
, pp. 41-53
-
-
Viollet, B.1
Foretz, M.2
Guigas, B.3
Horman, S.4
Dentin, R.5
Bertrand, L.6
Hue, L.7
Andreelli, F.8
-
188
-
-
84870408095
-
Nuclear receptors and transcription factors in the development of fatty liver disease
-
Vluggens A, Reddy JK (2012) Nuclear receptors and transcription factors in the development of fatty liver disease. Curr Drug Metab 13(10): 1422-1435
-
(2012)
Curr Drug Metab
, vol.13
, Issue.10
, pp. 1422-1435
-
-
Vluggens, A.1
Reddy, J.K.2
-
189
-
-
77954488637
-
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
-
Walker AK, Yang F, Jiang K, Ji J-Y, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ (2010) Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev 24(13): 1403-1417
-
(2010)
Genes Dev
, vol.24
, Issue.13
, pp. 1403-1417
-
-
Walker, A.K.1
Yang, F.2
Jiang, K.3
Ji, J.-Y.4
Watts, J.L.5
Purushotham, A.6
Boss, O.7
Hirsch, M.L.8
Ribich, S.9
Smith, J.J.10
-
190
-
-
80555146753
-
Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance
-
Wang R-H, Kim H-S, Xiao C, Xu X, Gavrilova O, Deng C-X (2011) Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance. J Clin Invest 121(11): 4477
-
(2011)
J Clin Invest
, vol.121
, Issue.11
, pp. 4477
-
-
Wang, R.-H.1
Kim, H.-S.2
Xiao, C.3
Xu, X.4
Gavrilova, O.5
Deng, C.-X.6
-
191
-
-
38549086019
-
FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
-
Welcker M, Clurman BE (2008) FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer 8(2): 83-93
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.2
, pp. 83-93
-
-
Welcker, M.1
Clurman, B.E.2
-
192
-
-
0037300799
-
A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance
-
Wells L, Vosseller K, Hart G (2003) A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance. Cell Mol Life Sci 60(2): 222-228
-
(2003)
Cell Mol Life Sci
, vol.60
, Issue.2
, pp. 222-228
-
-
Wells, L.1
Vosseller, K.2
Hart, G.3
-
193
-
-
84877731629
-
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity
-
Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN (2013) An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Res 73(9): 2850-2862
-
(2013)
Cancer Res
, vol.73
, Issue.9
, pp. 2850-2862
-
-
Williams, K.J.1
Argus, J.P.2
Zhu, Y.3
Wilks, M.Q.4
Marbois, B.N.5
York, A.G.6
Kidani, Y.7
Pourzia, A.L.8
Akhavan, D.9
Lisiero, D.N.10
-
194
-
-
84887568463
-
Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP
-
(NIH Public Access)
-
Xu X, So J-S, Park J-G, Lee A-H (2013) Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP. Semin Liver Dis 33(4): 301-311 (NIH Public Access)
-
(2013)
Semin Liver Dis
, vol.33
, Issue.4
, pp. 301-311
-
-
Xu, X.1
So, J.-S.2
Park, J.-G.3
Lee, A.-H.4
-
195
-
-
0037205433
-
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance inLep ob/Lep ob mice
-
Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y (2002) Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance inLep ob/Lep ob mice. J Biol Chem 277(22): 19353-19357
-
(2002)
J Biol Chem
, vol.277
, Issue.22
, pp. 19353-19357
-
-
Yahagi, N.1
Shimano, H.2
Hasty, A.H.3
Matsuzaka, T.4
Ide, T.5
Yoshikawa, T.6
Amemiya-Kudo, M.7
Tomita, S.8
Okazaki, H.9
Tamura, Y.10
-
196
-
-
34250356015
-
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
-
Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, Pandey SK, Bhanot S, Monia BP, Li YX, Diehl AM (2007) Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology 45(6): 1366-1374
-
(2007)
Hepatology
, vol.45
, Issue.6
, pp. 1366-1374
-
-
Yamaguchi, K.1
Yang, L.2
McCall, S.3
Huang, J.4
Yu, X.X.5
Pandey, S.K.6
Bhanot, S.7
Monia, B.P.8
Li, Y.X.9
Diehl, A.M.10
-
197
-
-
0035979214
-
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
-
Yamashita H, Takenoshita M, Sakurai M, Bruick RK, Henzel WJ, Shillinglaw W, Arnot D, Uyeda K (2001) A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Proc Natl Acad Sci U S A 98(16): 9116-9121
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.16
, pp. 9116-9121
-
-
Yamashita, H.1
Takenoshita, M.2
Sakurai, M.3
Bruick, R.K.4
Henzel, W.J.5
Shillinglaw, W.6
Arnot, D.7
Uyeda, K.8
-
198
-
-
70350452395
-
Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice
-
Yamazaki Y, Usui I, Kanatani Y, Matsuya Y, Tsuneyama K, Fujisaka S, Bukhari A, Suzuki H, Senda S, Imanishi S (2009) Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice. Am J Physiol Endocrinol Metab 297(5): E1179-E1186
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
, Issue.5
, pp. E1179-E1186
-
-
Yamazaki, Y.1
Usui, I.2
Kanatani, Y.3
Matsuya, Y.4
Tsuneyama, K.5
Fujisaka, S.6
Bukhari, A.7
Suzuki, H.8
Senda, S.9
Imanishi, S.10
-
199
-
-
42249098410
-
Chronic activation of AMP-activated protein kinase-alpha1 in liver leads to decreased adiposity in mice
-
Yang J, Maika S, Craddock L, King JA, Liu Z-M (2008) Chronic activation of AMP-activated protein kinase-alpha1 in liver leads to decreased adiposity in mice. Biochem Biophys Res Commun 370(2): 248-253
-
(2008)
Biochem Biophys Res Commun
, vol.370
, Issue.2
, pp. 248-253
-
-
Yang, J.1
Maika, S.2
Craddock, L.3
King, J.A.4
Liu, Z.-M.5
-
200
-
-
62649093597
-
AMP-activated protein kinase suppresses LXRdependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McARH7777 cells
-
Yang J, Craddock L, Hong S, Liu ZM (2009) AMP-activated protein kinase suppresses LXRdependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McARH7777 cells. J Cell Biochem 106(3): 414-426
-
(2009)
J Cell Biochem
, vol.106
, Issue.3
, pp. 414-426
-
-
Yang, J.1
Craddock, L.2
Hong, S.3
Liu, Z.M.4
-
201
-
-
79960131362
-
Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription
-
Yap F, Craddock L, Yang J (2011) Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription. Int J Biol Sci 7(5): 645
-
(2011)
Int J Biol Sci
, vol.7
, Issue.5
, pp. 645
-
-
Yap, F.1
Craddock, L.2
Yang, J.3
-
203
-
-
79960960007
-
Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways
-
Yecies JL, Zhang HH, Menon S, Liu S, Yecies D, Lipovsky AI, Gorgun C, Kwiatkowski DJ, Hotamisligil GS, Lee C-H (2011) Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways. Cell Metab 14(1): 21-32
-
(2011)
Cell Metab
, vol.14
, Issue.1
, pp. 21-32
-
-
Yecies, J.L.1
Zhang, H.H.2
Menon, S.3
Liu, S.4
Yecies, D.5
Lipovsky, A.I.6
Gorgun, C.7
Kwiatkowski, D.J.8
Hotamisligil, G.S.9
Lee, C.-H.10
-
204
-
-
65549171104
-
Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles
-
Yellaturu CR, Deng X, Cagen LM, Wilcox HG, Mansbach CM, Siddiqi SA, Park EA, Raghow R, Elam MB (2009) Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles. J Biol Chem 284(12): 7518-7532
-
(2009)
J Biol Chem
, vol.284
, Issue.12
, pp. 7518-7532
-
-
Yellaturu, C.R.1
Deng, X.2
Cagen, L.M.3
Wilcox, H.G.4
Mansbach, C.M.5
Siddiqi, S.A.6
Park, E.A.7
Raghow, R.8
Elam, M.B.9
-
205
-
-
25644448266
-
Fat in the liver and insulin resistance
-
Yki-Järvinen H (2005) Fat in the liver and insulin resistance. Ann Med 37(5): 347-356
-
(2005)
Ann Med
, vol.37
, Issue.5
, pp. 347-356
-
-
Yki-Järvinen, H.1
-
206
-
-
0141828972
-
Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis
-
Yu S, Rao S, Reddy JK (2003) Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis. Curr Mol Med 3(6): 561-572
-
(2003)
Curr Mol Med
, vol.3
, Issue.6
, pp. 561-572
-
-
Yu, S.1
Rao, S.2
Reddy, J.K.3
-
207
-
-
1842509855
-
ATF6 modulates SREBP2-mediated lipogenesis
-
Zeng L, Lu M, Mori K, Luo S, Lee AS, Zhu Y, Shyy JYJ (2004) ATF6 modulates SREBP2-mediated lipogenesis. EMBO J 23(4): 950-958
-
(2004)
EMBO J
, vol.23
, Issue.4
, pp. 950-958
-
-
Zeng, L.1
Lu, M.2
Mori, K.3
Luo, S.4
Lee, A.S.5
Zhu, Y.6
Shyy, J.Y.J.7
-
208
-
-
79953794116
-
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis
-
Zhang K, Wang S, Malhotra J, Hassler JR, Back SH, Wang G, Chang L, Xu W, Miao H, Leonardi R (2011) The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis. EMBO J 30(7): 1357-1375
-
(2011)
EMBO J
, vol.30
, Issue.7
, pp. 1357-1375
-
-
Zhang, K.1
Wang, S.2
Malhotra, J.3
Hassler, J.R.4
Back, S.H.5
Wang, G.6
Chang, L.7
Xu, W.8
Miao, H.9
Leonardi, R.10
-
209
-
-
84907164609
-
Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling
-
Zhang D, Tong X, Arthurs B, Guha A, Rui L, Kamath A, Inoki K, Yin L (2014) Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling. J Biol Chem 289(37): 25925-25935
-
(2014)
J Biol Chem
, vol.289
, Issue.37
, pp. 25925-25935
-
-
Zhang, D.1
Tong, X.2
Arthurs, B.3
Guha, A.4
Rui, L.5
Kamath, A.6
Inoki, K.7
Yin, L.8
-
210
-
-
84863552454
-
Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1
-
Zhao X, Feng D, Wang Q, Abdulla A, Xie X-J, Zhou J, Sun Y, Yang ES, Liu L-P, Vaitheesvaran B (2012) Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. J Clin Invest 122(7): 2417
-
(2012)
J Clin Invest
, vol.122
, Issue.7
, pp. 2417
-
-
Zhao, X.1
Feng, D.2
Wang, Q.3
Abdulla, A.4
Xie, X.-J.5
Zhou, J.6
Sun, Y.7
Yang, E.S.8
Liu, L.-P.9
Vaitheesvaran, B.10
-
211
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N (2001) Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108(8): 1167
-
(2001)
J Clin Invest
, vol.108
, Issue.8
, pp. 1167
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
|