A phosphorylation cascade controls the degradation of active SREBP1

Journal of Biological Chemistry

Volumn 284, Issue 9, 2009, Pages 5885-5895

  Bengoechea Alonso, Maria T ^a,b   Ericsson, Johan ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

C-TERMINAL DOMAINS; CASCADE CONTROL; DOCKING SITES; GLYCOGEN SYNTHASE KINASE-3; IN-CELL; INSULIN SIGNALING; LIPID METABOLISMS; MOLECULAR SWITCHES; PHOSPHORYLATION SITES; POST-TRANSLATIONAL MODIFICATIONS; STEROL REGULATORY ELEMENT-BINDING PROTEINS; UBIQUITIN LIGASE;

CASCADE CONTROL SYSTEMS; DEGRADATION; ENZYMES; INSULIN; TRANSCRIPTION; TRANSCRIPTION FACTORS;

PHOSPHORYLATION;

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; GLYCOGEN SYNTHASE PHOSPHATASE; INSULIN; MUTANT PROTEIN; SERINE; SMALL INTERFERING RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; THREONINE; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE FBW7; UNCLASSIFIED DRUG; BETA GALACTOSIDASE; CELL CYCLE PROTEIN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; GLYCOGEN SYNTHASE KINASE 3; LUCIFERASE; MESSENGER RNA; SREBF1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DNA BINDING; GENE INACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; GENETICS; HELA CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; METABOLISM; PHOSPHORYLATION; PROMOTER REGION; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UBIQUITINATION;

BETA-GALACTOSIDASE; CELL CYCLE PROTEINS; F-BOX PROTEINS; GLYCOGEN SYNTHASE KINASE 3; HELA CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INSULIN; LUCIFERASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 65549140251     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807906200     Document Type: Article

References (40)

1. Brown, M. S., and Goldstein, J. L. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11041-11048
2. Osborne, T. F. (2000) J. Biol. Chem. 275, 32379-32382
3. Bengoechea-Alonso, M. T., and Ericsson, J. (2007) Curr. Opin. Cell Biol. 19, 215-222
4. Espenshade, P. J. (2006) J. Cell Sci. 119, 973-976
5. Rawson, R. B. (2003) Nat. Rev. Mol. Cell. Biol. 4, 631-640
6. Goldstein, J. L., Debose-Boyd, R. A., and Brown, M. S. (2006) Cell 124, 35-46
7. Horton, J. D., Goldstein, J. L., and Brown, M. S. (2002) J. Clin. Investig. 109, 1125-1131
8. Kotzka, J., Lehr, S., Roth, G., Avci, H., Knebel, B., and Muller-Wieland, D. (2004) J. Biol. Chem. 279, 22404-22411
9. Sundqvist, A., Bengoechea-Alonso, M. T., Ye, X., Lukiyanchuk, V., Jin, J., Harper, J. W., and Ericsson, J. (2005) Cell Metab. 1, 379-391
10. Bengoechea-Alonso, M. T., Punga, T., and Ericsson, J. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 11681-11686
11. Bengoechea-Alonso, M. T., and Ericsson, J. (2006) Cell Cycle 5, 1708-1718
12. Punga, T., Bengoechea-Alonso, M. T., and Ericsson, J. (2006) J. Biol. Chem. 281, 25278-25286
13. Giandomenico, V., Simonsson, M., Gronroos, E., and Ericsson, J. (2003) Mol. Cell. Biol. 23, 2587-2599
14. Hirano, Y., Murata, S., Tanaka, K., Shimizu, M., and Sato, R. (2003) J. Biol. Chem. 278, 16809-16819
15. Sundqvist, A., and Ericsson, J. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 13833-13838
16. Hirano, Y., Yoshida, M., Shimizu, M., and Sato, R. (2001) J. Biol. Chem. 276, 36431-36437
17. Muratani, M., and Tansey, W. P. (2003) Nat. Rev. Mol. Cell Biol. 4, 192-201
18. Lipford, J. R., and Deshaies, R. J. (2003) Nat. Cell Biol. 5, 845-850
19. Welcker, M., and Clurman, B. E. (2007) Nat. Rev. Cancer 20, 83-93
20. Koepp, D. M., Schaefer, L. K., Ye, X., Keyomarsi, K., Chu, C., Harper, J. W., and Elledge, S. J. (2001) Science 294, 173-177
21. Strohmaier, H., Spruck, C. H., Kaiser, P., Won, K. A., Sangfelt, O., and Reed, S. I. (2001) Nature 413, 316-322
22. Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K., and Nakayama, K. I. (2004) EMBO J. 23, 2116-2125
23. Welcker, M., Orian, A., Jin, J., Grim, J. E., Harper, J. W., Eisenman, R. N., and Clurman, B. E. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 9085-9090
24. Oberg, C., Li, J., Pauley, A., Wolf, E., Gurney, M., and Lendahl, U. (2001) J. Biol. Chem. 276, 35847-35853
25. Wu, G., Lyapina, S., Das, I., Li, J., Gurney, M., Pauley, A., Chui, I., Deshaies, R. J., and Kitajewski, J. (2001) Mol. Cell. Biol. 21, 7403-7415
26. Tetzlaff, M. T., Yu, W., Li, M., Zhang, P., Finegold, M., Mahon, K., Harper, J. W., Schwartz, R. J., and Elledge, S. J. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 3338-3345
27. Tsunematsu, R., Nakayama, K., Oike, Y., Nishiyama, M., Ishida, N., Hatakeyama, S., Bessho, Y., Kageyama, R., Suda, T., and Nakayama, K. I. (2004) J. Biol. Chem. 279, 9417-9423
28. Wei, W., Jin, J., Schlisio, S., Harper, J. W., and Kaelin, W. G., Jr. (2005) Cancer Cell 8, 25-33
29. Olson, B. L., Hock, M. B., Ekholm-Reed, S., Wohlschlegel, J. A., Dev, K. K., Kralli, A., and Reed, S. I. (2008) Genes Dev. 22, 252-264
30. Wu, R. C., Feng, Q., Lonard, D. M., and O'Malley, B. W. (2007) Cell 129, 1125-1140
31. Rajagopalan, H., Jallepalli, P. V., Rago, C., Velculescu, V. E., Kinzler, K. W., Vogelstein, B., and Lengauer, C. (2004) Nature 428, 77-81
32. Ericsson, J., Jackson, S. M., and Edwards, P. A. (1996) J. Biol. Chem. 271, 24359-24364
33. Cohen, P., and Frame, S. (2001) Nat. Rev. Mo. Cell Biol. 2, 769-776
34. Ferre, P., and Foufelle, F. (2007) Horm. Res. (Basel) 68, 72-82
35. Doble, B. W., and Woodgett, J. R. (2003) J. Cell Sci. 116, 1175-1186
36. Jope, R. S., and Johnson, G. V. (2004) Trends Biochem. Sci. 29, 95-102
37. Frame, S., and Cohen, P. (2001) Biochem. J. 359, 1-16
38. Forde, J. E., and Dale, T. C. (2007) Cell. Mol. Life Sci. 64, 1930-1944
39. Mao, J.-H., Kim, I.-J., Wu, D., Climent, J., Kang, H. C., DelRosario, R., and Balmain, A. (2008) Science 321, 1499-1502
40. Porstmann, T., Santos, C. R., Griffiths, B., Cully, M., Wu, M., Leevers, S., Griffiths, J. R., Chung, Y. L., and Schulze, A. (2008) Cell Metab. 8, 224-236