-
1
-
-
84925351121
-
A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish
-
Ablain, J., Durand, E. M., Yang, S., Zhou, Y., & Zon, L. I., (2015). A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish. Developmental Cell, 32, 756–764.10.1016/j.devcel.2015.01.032
-
(2015)
Developmental Cell
, vol.32
, pp. 756-764
-
-
Ablain, J.1
Durand, E.M.2
Yang, S.3
Zhou, Y.4
Zon, L.I.5
-
2
-
-
84938945636
-
Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice
-
Aida, T., Chiyo, K., Usami, T., Ishikubo, H., Imahashi, R., Wada, Y., … Tanaka, K., (2015). Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice. Genome Biology, 16, 87.10.1186/s13059-015-0653-x
-
(2015)
Genome Biology
, vol.16
, pp. 87
-
-
Aida, T.1
Chiyo, K.2
Usami, T.3
Ishikubo, H.4
Imahashi, R.5
Wada, Y.6
Tanaka, K.7
-
3
-
-
84959101230
-
Metabolic engineering of Saccharomyces cerevisiae for linalool production
-
Amiri, P., Shahpiri, A., Asadollahi, M. A., Momenbeik, F., & Partow, S., (2015). Metabolic engineering of Saccharomyces cerevisiae for linalool production. Biotechnology Letters, 38, 503–508.
-
(2015)
Biotechnology Letters
, vol.38
, pp. 503-508
-
-
Amiri, P.1
Shahpiri, A.2
Asadollahi, M.A.3
Momenbeik, F.4
Partow, S.5
-
4
-
-
1642325279
-
Life and death in mammalian cell culture: Strategies for apoptosis inhibition
-
Arden, N., & Betenbaugh, M. J., (2004). Life and death in mammalian cell culture:Strategies for apoptosis inhibition. Trends in Biotechnology, 22, 174–180.10.1016/j.tibtech.2004.02.004
-
(2004)
Trends in Biotechnology
, vol.22
, pp. 174-180
-
-
Arden, N.1
Betenbaugh, M.J.2
-
5
-
-
38049001166
-
Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
-
Atsumi, S., Hanai, T., & Liao, J. C., (2008). Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature, 451, 86–89.10.1038/nature06450
-
(2008)
Nature
, vol.451
, pp. 86-89
-
-
Atsumi, S.1
Hanai, T.2
Liao, J.C.3
-
6
-
-
84929572600
-
Homology-integrated CRISPR–Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae
-
Bao, Z., Xiao, H., Liang, J., Zhang, L., Xiong, X., Sun, N., … Zhao, H., (2015a). Homology-integrated CRISPR–Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae. ACS Synthetic Biology, 4, 585–594.10.1021/sb500255k
-
(2015)
ACS Synthetic Biology
, vol.4
, pp. 585-594
-
-
Bao, Z.1
Xiao, H.2
Liang, J.3
Zhang, L.4
Xiong, X.5
Sun, N.6
Zhao, H.7
-
7
-
-
84929572600
-
Homology-integrated CRISPR–Cas (HI-CRISPR) System for one-step multigene disruption in Saccharomyces cerevisiae
-
Bao, Z., Xiao, H., Liang, J., Zhang, L., Xiong, X., Sun, N., … Zhao, H., (2015b). Homology-integrated CRISPR–Cas (HI-CRISPR) System for one-step multigene disruption in Saccharomyces cerevisiae. ACS Synthetic Biology, 4, 585–594.10.1021/sb500255k
-
(2015)
ACS Synthetic Biology
, vol.4
, pp. 585-594
-
-
Bao, Z.1
Xiao, H.2
Liang, J.3
Zhang, L.4
Xiong, X.5
Sun, N.6
Zhao, H.7
-
8
-
-
84871318613
-
Enhancing E. coli tolerance towards oxidative stress via engineering its global regulator cAMP receptor protein (CRP)
-
Basak, S., & Jiang, R., (2012). Enhancing E. coli tolerance towards oxidative stress via engineering its global regulator cAMP receptor protein (CRP). PLoS ONE, 7, e51179.10.1371/journal.pone.0051179
-
(2012)
PLoS ONE
, vol.7
, pp. e51179
-
-
Basak, S.1
Jiang, R.2
-
9
-
-
84893709652
-
CRISPR/Cas9 and genome editing in drosophila
-
Bassett, A. R., & Liu, J.-L., (2014). CRISPR/Cas9 and genome editing in drosophila. Journal of Genetics and Genomics, 41, 7–19.10.1016/j.jgg.2013.12.004
-
(2014)
Journal of Genetics and Genomics
, vol.41
, pp. 7-19
-
-
Bassett, A.R.1
Liu, J.-L.2
-
10
-
-
84892437994
-
Highly efficient targeted mutagenesis of drosophila with the CRISPR/Cas9 system
-
Bassett, A. R., Tibbit, C., Ponting, C. P., & Liu, J.-L., (2013a). Highly efficient targeted mutagenesis of drosophila with the CRISPR/Cas9 system. Cell Reports, 4, 220–228.10.1016/j.celrep.2013.06.020
-
(2013)
Cell Reports
, vol.4
, pp. 220-228
-
-
Bassett, A.R.1
Tibbit, C.2
Ponting, C.P.3
Liu, J.-L.4
-
11
-
-
85018083544
-
Mutagenesis and homologous recombination in Drosophila cell lines using CRISPR/Cas9
-
BIO20137120
-
Bassett, A. R., Tibbit, C., Ponting, C. P., Liu, J.-L., 2013b. Mutagenesis and homologous recombination in Drosophila cell lines using CRISPR/Cas9. Biology Open, BIO20137120.
-
(2013)
Biology Open
-
-
Bassett, A.R.1
Tibbit, C.2
Ponting, C.P.3
Liu, J.-L.4
-
12
-
-
80755187812
-
CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation
-
Bhaya, D., Davison, M., & Barrangou, R., (2011). CRISPR-Cas systems in bacteria and archaea:versatile small RNAs for adaptive defense and regulation. Annual Review of Genetics, 45, 273–297.10.1146/annurev-genet-110410-132430
-
(2011)
Annual Review of Genetics
, vol.45
, pp. 273-297
-
-
Bhaya, D.1
Davison, M.2
Barrangou, R.3
-
13
-
-
77955716950
-
Metabolic engineering of Escherichia coli for the production of succinate from glycerol
-
Blankschien, M. D., Clomburg, J. M., & Gonzalez, R., (2010). Metabolic engineering of Escherichia coli for the production of succinate from glycerol. Metabolic Engineering, 12, 409–419.10.1016/j.ymben.2010.06.002
-
(2010)
Metabolic Engineering
, vol.12
, pp. 409-419
-
-
Blankschien, M.D.1
Clomburg, J.M.2
Gonzalez, R.3
-
14
-
-
0035209901
-
Metabolic engineering for microbial production of aromatic amino acids and derived compounds
-
Bongaerts, J., Krämer, M., Müller, U., Raeven, L., & Wubbolts, M., (2001). Metabolic engineering for microbial production of aromatic amino acids and derived compounds. Metabolic Engineering, 3, 289–300.10.1006/mben.2001.0196
-
(2001)
Metabolic Engineering
, vol.3
, pp. 289-300
-
-
Bongaerts, J.1
Krämer, M.2
Müller, U.3
Raeven, L.4
Wubbolts, M.5
-
15
-
-
84917692795
-
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos
-
Brandl, C., Ortiz, O., Röttig, B., Wefers, B., Wurst, W., & Kühn, R., (2015). Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos. FEBS Open Bio, 5, 26–35.10.1016/j.fob.2014.11.009
-
(2015)
FEBS Open Bio
, vol.5
, pp. 26-35
-
-
Brandl, C.1
Ortiz, O.2
Röttig, B.3
Wefers, B.4
Wurst, W.5
Kühn, R.6
-
16
-
-
84939207951
-
Metabolic engineering of Escherichia coli for the production of 1,3-diaminopropane, a three carbon diamine
-
Chae, T. U., Kim, W. J., Choi, S., Park, S. J., & Lee, S. Y., (2015). Metabolic engineering of Escherichia coli for the production of 1,3-diaminopropane, a three carbon diamine. Scientific Reports, 5, 13040.10.1038/srep13040
-
(2015)
Scientific Reports
, vol.5
, pp. 13040
-
-
Chae, T.U.1
Kim, W.J.2
Choi, S.3
Park, S.J.4
Lee, S.Y.5
-
17
-
-
84876409836
-
Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos
-
Chang, N., Sun, C., Gao, L., Zhu, D., Xu, X., Zhu, X., … Xi, J. J., (2013). Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos. Cell Research, 23, 465–472.10.1038/cr.2013.45
-
(2013)
Cell Research
, vol.23
, pp. 465-472
-
-
Chang, N.1
Sun, C.2
Gao, L.3
Zhu, D.4
Xu, X.5
Zhu, X.6
Xi, J.J.7
-
18
-
-
84925662286
-
Targeted germline modifications in rats using CRISPR/Cas9 and spermatogonial stem cells
-
Chapman, K. M., Medrano, G. A., Jaichander, P., Chaudhary, J., Waits, A. E., Nobrega, M. A., … Hamra, F. K., (2015). Targeted germline modifications in rats using CRISPR/Cas9 and spermatogonial stem cells. Cell Reports, 10, 1828–1835.10.1016/j.celrep.2015.02.040
-
(2015)
Cell Reports
, vol.10
, pp. 1828-1835
-
-
Chapman, K.M.1
Medrano, G.A.2
Jaichander, P.3
Chaudhary, J.4
Waits, A.E.5
Nobrega, M.A.6
Hamra, F.K.7
-
19
-
-
84874745737
-
Biotechnology: Rewriting a genome
-
Charpentier, E., & Doudna, J. A., (2013). Biotechnology:Rewriting a genome. Nature, 495, 50–51.10.1038/495050a
-
(2013)
Nature
, vol.495
, pp. 50-51
-
-
Charpentier, E.1
Doudna, J.A.2
-
20
-
-
84911937787
-
Genome editing in human pluripotent stem cells using site-specific nucleases
-
New York, NY: Springer
-
Chiba, K., & Hockemeyer, D., 2015. Genome editing in human pluripotent stem cells using site-specific nucleases. In Chromosomal Mutagenesis (pp. 267–280). New York, NY:Springer.
-
(2015)
Chromosomal Mutagenesis
, pp. 267-280
-
-
Chiba, K.1
Hockemeyer, D.2
-
21
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
-
Cho, S. W., Kim, S., Kim, J. M., & Kim, J.-S., (2013a). Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nature Biotechnology, 31, 230–232.10.1038/nbt.2507
-
(2013)
Nature Biotechnology
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
Kim, J.-S.4
-
22
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
-
Cho, S. W., Kim, S., Kim, J. M., & Kim, J.-S., (2013b). Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nature Biotechnology, 31, 230–232.10.1038/nbt.2507
-
(2013)
Nature Biotechnology
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
Kim, J.-S.4
-
23
-
-
84894268220
-
Enhancing E. coli isobutanol tolerance through engineering its global transcription factor cAMP receptor protein (CRP)
-
Chong, H., Geng, H., Zhang, H., Song, H., Huang, L., & Jiang, R., (2014). Enhancing E. coli isobutanol tolerance through engineering its global transcription factor cAMP receptor protein (CRP). Biotechnology and Bioengineering, 111, 700–708.10.1002/bit.25134
-
(2014)
Biotechnology and Bioengineering
, vol.111
, pp. 700-708
-
-
Chong, H.1
Geng, H.2
Zhang, H.3
Song, H.4
Huang, L.5
Jiang, R.6
-
24
-
-
84902095351
-
Classification and evolution of type II CRISPR-Cas systems
-
Chylinski, K., Makarova, K. S., Charpentier, E., & Koonin, E. V., (2014). Classification and evolution of type II CRISPR-Cas systems. Nucleic Acids Research, 42, 6091–6105.10.1093/nar/gku241
-
(2014)
Nucleic Acids Research
, vol.42
, pp. 6091-6105
-
-
Chylinski, K.1
Makarova, K.S.2
Charpentier, E.3
Koonin, E.V.4
-
25
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., … Marraffini, L. A., (2013). Multiplex genome engineering using CRISPR/Cas systems. Science, 339, 819–823.10.1126/science.1231143
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Marraffini, L.A.7
-
26
-
-
50349083723
-
Insight into microevolution of Yersinia pestis by clustered regularly interspaced short palindromic repeats
-
Cui, Y., Li, Y., Gorgé, O., Platonov, M. E., Yan, Y., Guo, Z., … Wang, X., (2008). Insight into microevolution of Yersinia pestis by clustered regularly interspaced short palindromic repeats. PLoS ONE, 3, e2652–e2652.10.1371/journal.pone.0002652
-
(2008)
PLoS ONE
, vol.3
, pp. e2652
-
-
Cui, Y.1
Li, Y.2
Gorgé, O.3
Platonov, M.E.4
Yan, Y.5
Guo, Z.6
Wang, X.7
-
27
-
-
84884934527
-
The secretory pathway: Exploring yeast diversity
-
Delic, M., Valli, M., Graf, A. B., Pfeffer, M., Mattanovich, D., & Gasser, B., (2013). The secretory pathway:Exploring yeast diversity. FEMS Microbiology Reviews, 37, 872–914.10.1111/1574-6976.12020
-
(2013)
FEMS Microbiology Reviews
, vol.37
, pp. 872-914
-
-
Delic, M.1
Valli, M.2
Graf, A.B.3
Pfeffer, M.4
Mattanovich, D.5
Gasser, B.6
-
28
-
-
84897546101
-
Engineering of protein folding and secretion–strategies to overcome bottlenecks for efficient production of recombinant proteins
-
Delic, M., Göngrich, R., Mattanovich, D., & Gasser, B., (2014). Engineering of protein folding and secretion–strategies to overcome bottlenecks for efficient production of recombinant proteins. Antioxidants & Redox Signaling, 21, 414–437.10.1089/ars.2014.5844
-
(2014)
Antioxidants & Redox Signaling
, vol.21
, pp. 414-437
-
-
Delic, M.1
Göngrich, R.2
Mattanovich, D.3
Gasser, B.4
-
29
-
-
79953250082
-
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
-
Deltcheva, E., Chylinski, K., Sharma, C. M., Gonzales, K., Chao, Y., Pirzada, Z. A., … Charpentier, E., (2011). CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature, 471, 602–607.10.1038/nature09886
-
(2011)
Nature
, vol.471
, pp. 602-607
-
-
Deltcheva, E.1
Chylinski, K.2
Sharma, C.M.3
Gonzales, K.4
Chao, Y.5
Pirzada, Z.A.6
Charpentier, E.7
-
30
-
-
84876575031
-
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
-
gkt135
-
DiCarlo, J. E., Norville, J. E., Mali, P., Rios, X., Aach, J., & Church, G. M., 2013. Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Research, gkt135.
-
(2013)
Nucleic Acids Research
-
-
DiCarlo, J.E.1
Norville, J.E.2
Mali, P.3
Rios, X.4
Aach, J.5
Church, G.M.6
-
31
-
-
84944155176
-
Overexpression of acetyl-CoA synthetase in Saccharomyces cerevisiae increases acetic acid tolerance
-
Ding, J., Holzwarth, G., Penner, M. H., Patton-Vogt, J., & Bakalinsky, A. T., (2015). Overexpression of acetyl-CoA synthetase in Saccharomyces cerevisiae increases acetic acid tolerance. FEMS Microbiology Letters, 362, 1–7.10.1093/femsle/fnu042
-
(2015)
FEMS Microbiology Letters
, vol.362
, pp. 1-7
-
-
Ding, J.1
Holzwarth, G.2
Penner, M.H.3
Patton-Vogt, J.4
Bakalinsky, A.T.5
-
32
-
-
84883305437
-
Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
-
Ebina, H., Misawa, N., Kanemura, Y., & Koyanagi, Y., 2013. Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus. Scientific Reports 3.
-
(2013)
Scientific Reports 3
-
-
Ebina, H.1
Misawa, N.2
Kanemura, Y.3
Koyanagi, Y.4
-
33
-
-
84873800970
-
Genome-scale engineering for systems and synthetic biology
-
Esvelt, K. M., & Wang, H. H., (2013). Genome-scale engineering for systems and synthetic biology. Molecular Systems Biology, 9, 641–641.
-
(2013)
Molecular Systems Biology
, vol.9
, pp. 641
-
-
Esvelt, K.M.1
Wang, H.H.2
-
34
-
-
84904463436
-
Critical factors affecting the success of cloning, expression, and mass production of enzymes by recombinant E. coli
-
Fakruddin, M., Mohammad Mazumdar, R., Bin Mannan, K. S., Chowdhury, A., & Hossain, M. N., (2013). Critical factors affecting the success of cloning, expression, and mass production of enzymes by recombinant E. coli. ISRN Biotechnology, 2013, 7.
-
(2013)
ISRN Biotechnology
, vol.2013
, pp. 7
-
-
Fakruddin, M.1
Mohammad Mazumdar, R.2
Bin Mannan, K.S.3
Chowdhury, A.4
Hossain, M.N.5
-
35
-
-
78751528914
-
A vector set for systematic metabolic engineering in Saccharomyces cerevisiae
-
Fang, F., Salmon, K., Shen, M. W. Y., Aeling, K. A., Ito, E., Irwin, B., … Sandmeyer, S., (2011). A vector set for systematic metabolic engineering in Saccharomyces cerevisiae. Yeast, 28, 123–136.10.1002/yea.v28.2
-
(2011)
Yeast
, vol.28
, pp. 123-136
-
-
Fang, F.1
Salmon, K.2
Shen, M.W.Y.3
Aeling, K.A.4
Ito, E.5
Irwin, B.6
Sandmeyer, S.7
-
36
-
-
84885181396
-
Efficient genome editing in plants using a CRISPR/Cas system
-
Feng, Z., Zhang, B., Ding, W., Liu, X., Yang, D.-L., Wei, P., … Zhu, J.-K., (2013). Efficient genome editing in plants using a CRISPR/Cas system. Cell Research, 23, 1229–1232.10.1038/cr.2013.114
-
(2013)
Cell Research
, vol.23
, pp. 1229-1232
-
-
Feng, Z.1
Zhang, B.2
Ding, W.3
Liu, X.4
Yang, D.-L.5
Wei, P.6
Zhu, J.-K.7
-
37
-
-
84866859751
-
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
-
Gasiunas, G., Barrangou, R., Horvath, P., & Siksnys, V., (2012). Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proceedings of the National Academy of Sciences, 109, E2579–E2586.10.1073/pnas.1208507109
-
(2012)
Proceedings of the National Academy of Sciences
, vol.109
, pp. E2579-E2586
-
-
Gasiunas, G.1
Barrangou, R.2
Horvath, P.3
Siksnys, V.4
-
38
-
-
84907546229
-
Metabolic engineering of Saccharomyces cerevisiae for production of butanol isomers
-
Generoso, W. C., Schadeweg, V., Oreb, M., & Boles, E., (2015). Metabolic engineering of Saccharomyces cerevisiae for production of butanol isomers. Current Opinion in Biotechnology, 33, 1–7.10.1016/j.copbio.2014.09.004
-
(2015)
Current Opinion in Biotechnology
, vol.33
, pp. 1-7
-
-
Generoso, W.C.1
Schadeweg, V.2
Oreb, M.3
Boles, E.4
-
39
-
-
84930664946
-
Metabolic engineering for the high-yield production of isoprenoid-based C5 alcohols in E. coli
-
George, K. W., Thompson, M. G., Kang, A., Baidoo, E., Wang, G., Chan, L. J. G., … Soon Lee, T., 2015. Metabolic engineering for the high-yield production of isoprenoid-based C5 alcohols in E. coli. Scientific Reports, 5, 11128.10.1038/srep11128
-
(2015)
Scientific Reports, 5
, pp. 11128
-
-
George, K.W.1
Thompson, M.G.2
Kang, A.3
Baidoo, E.4
Wang, G.5
Chan, L.J.G.6
Soon Lee, T.7
-
40
-
-
84900458436
-
Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in drosophila
-
Gratz, S. J., Ukken, F. P., Rubinstein, C. D., Thiede, G., Donohue, L. K., Cummings, A. M., & O’Connor-Giles, K. M., (2014). Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in drosophila. Genetics, 196, 961–971.10.1534/genetics.113.160713
-
(2014)
Genetics
, vol.196
, pp. 961-971
-
-
Gratz, S.J.1
Ukken, F.P.2
Rubinstein, C.D.3
Thiede, G.4
Donohue, L.K.5
Cummings, A.M.6
O’Connor-Giles, K.M.7
-
41
-
-
0027724480
-
Nature of DNA polymorphism in the direct repeat cluster of Mycobacterium tuberculosis; application for strain differentiation by a novel typing method
-
Groenen, P., Bunschoten, A. E., Soolingen, D. V., & van Errtbden, J. D., (1993). Nature of DNA polymorphism in the direct repeat cluster of Mycobacterium tuberculosis; application for strain differentiation by a novel typing method. Molecular Microbiology, 10, 1057–1065.10.1111/mmi.1993.10.issue-5
-
(1993)
Molecular Microbiology
, vol.10
, pp. 1057-1065
-
-
Groenen, P.1
Bunschoten, A.E.2
Soolingen, D.V.3
van Errtbden, J.D.4
-
42
-
-
0036008140
-
VEGF 165 antisense RNA suppresses oncogenic properties of human esophageal squamous cell carcinoma
-
Gu, Z.-P., Wang, Y.-J., Li, J.-G., & Zhou, Y.-A., (2002). VEGF 165 antisense RNA suppresses oncogenic properties of human esophageal squamous cell carcinoma. World Journal of Gastroenterology, 8, 44–48.10.3748/wjg.v8.i1.44
-
(2002)
World Journal of Gastroenterology
, vol.8
, pp. 44-48
-
-
Gu, Z.-P.1
Wang, Y.-J.2
Li, J.-G.3
Zhou, Y.-A.4
-
43
-
-
84897594300
-
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system
-
Hai, T., Teng, F., Guo, R., Li, W., & Zhou, Q., (2014). One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. Cell Research, 24, 372–375.10.1038/cr.2014.11
-
(2014)
Cell Research
, vol.24
, pp. 372-375
-
-
Hai, T.1
Teng, F.2
Guo, R.3
Li, W.4
Zhou, Q.5
-
44
-
-
0142072824
-
Engineering Escherichia coli for increased productivity of serine-rich proteins based on proteome profiling
-
Han, M.-J., Jeong, K. J., Yoo, J.-S., & Lee, S. Y., (2003). Engineering Escherichia coli for increased productivity of serine-rich proteins based on proteome profiling. Applied and Environmental Microbiology, 69, 5772–5781.10.1128/AEM.69.10.5772-5781.2003
-
(2003)
Applied and Environmental Microbiology
, vol.69
, pp. 5772-5781
-
-
Han, M.-J.1
Jeong, K.J.2
Yoo, J.-S.3
Lee, S.Y.4
-
45
-
-
0029996016
-
Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes
-
Hanecak, R., Brown-Driver, V., Fox, M. C., Azad, R. F., Furusako, S., Nozaki, C., … Anderson, K. P., (1996). Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes. J Virol, 70, 5203–5212.
-
(1996)
J Virol
, vol.70
, pp. 5203-5212
-
-
Hanecak, R.1
Brown-Driver, V.2
Fox, M.C.3
Azad, R.F.4
Furusako, S.5
Nozaki, C.6
Anderson, K.P.7
-
46
-
-
84951568684
-
Applications of CRISPR-Cas systems in neuroscience
-
Heidenreich, M., & Zhang, F., (2016). Applications of CRISPR-Cas systems in neuroscience. Nat Rev Neurosci, 17, 36–44.
-
(2016)
Nat Rev Neurosci
, vol.17
, pp. 36-44
-
-
Heidenreich, M.1
Zhang, F.2
-
47
-
-
84949212657
-
TALEN‐and CRISPR/Cas9‐mediated gene editing in human pluripotent stem cells using lipid‐based transfection
-
5B. 3.1-5B. 3.25
-
Hendriks, W. T., Jiang, X., Daheron, L., & Cowan, C. A., 2015. TALEN‐and CRISPR/Cas9‐mediated gene editing in human pluripotent stem cells using lipid‐based transfection. Current Protocols in Stem Cell Biology, 5B. 3.1-5B. 3.25.
-
(2015)
Current Protocols in Stem Cell Biology
-
-
Hendriks, W.T.1
Jiang, X.2
Daheron, L.3
Cowan, C.A.4
-
48
-
-
84954289827
-
Genome editing in human pluripotent stem cells: Approaches, pitfalls, and solutions
-
Hendriks, W. T., Warren, C. R., & Cowan, C. A., (2016). Genome editing in human pluripotent stem cells:Approaches, pitfalls, and solutions. Cell Stem Cell, 18, 53–65.10.1016/j.stem.2015.12.002
-
(2016)
Cell Stem Cell
, vol.18
, pp. 53-65
-
-
Hendriks, W.T.1
Warren, C.R.2
Cowan, C.A.3
-
49
-
-
34447132252
-
Distinct expression patterns of natural antisense transcripts in arabidopsis
-
Henz, S. R., Cumbie, J. S., Kasschau, K. D., Lohmann, J. U., Carrington, J. C., Weigel, D., & Schmid, M., (2007). Distinct expression patterns of natural antisense transcripts in arabidopsis. Plant Physiology, 144, 1247–1255.10.1104/pp.107.100396
-
(2007)
Plant Physiology
, vol.144
, pp. 1247-1255
-
-
Henz, S.R.1
Cumbie, J.S.2
Kasschau, K.D.3
Lohmann, J.U.4
Carrington, J.C.5
Weigel, D.6
Schmid, M.7
-
50
-
-
74249095519
-
CRISPR/Cas, the immune system of bacteria and archaea
-
Horvath, P., & Barrangou, R., (2010). CRISPR/Cas, the immune system of bacteria and archaea. Science, 327, 167–170.10.1126/science.1179555
-
(2010)
Science
, vol.327
, pp. 167-170
-
-
Horvath, P.1
Barrangou, R.2
-
51
-
-
84888866065
-
Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish
-
Hruscha, A., Krawitz, P., Rechenberg, A., Heinrich, V., Hecht, J., Haass, C., & Schmid, B., (2013). Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish. Development, 140, 4982–4987.10.1242/dev.099085
-
(2013)
Development
, vol.140
, pp. 4982-4987
-
-
Hruscha, A.1
Krawitz, P.2
Rechenberg, A.3
Heinrich, V.4
Hecht, J.5
Haass, C.6
Schmid, B.7
-
52
-
-
84874617789
-
Efficient genome editing in zebrafish using a CRISPR-Cas system
-
Hwang, W. Y., Fu, Y., Reyon, D., Maeder, M. L., Tsai, S. Q., Sander, J. D., … Joung, J. K., (2013). Efficient genome editing in zebrafish using a CRISPR-Cas system. Nature Biotechnology, 31, 227–229.10.1038/nbt.2501
-
(2013)
Nature Biotechnology
, vol.31
, pp. 227-229
-
-
Hwang, W.Y.1
Fu, Y.2
Reyon, D.3
Maeder, M.L.4
Tsai, S.Q.5
Sander, J.D.6
Joung, J.K.7
-
53
-
-
84929616011
-
Targeted Mutagenesis in zebrafish using CRISPR RNA-guided nucleases
-
Hwang, W. Y., Fu, Y., Reyon, D., Gonzales, A. P., Joung, J. K., & Yeh, J.-R. J., (2015). Targeted Mutagenesis in zebrafish using CRISPR RNA-guided nucleases. CRISPR:Methods and protocols. 317–334.10.1007/978-1-4939-2687-9
-
(2015)
CRISPR: Methods and protocols
, pp. 317-334
-
-
Hwang, W.Y.1
Fu, Y.2
Reyon, D.3
Gonzales, A.P.4
Joung, J.K.5
Yeh, J.R.J.6
-
54
-
-
11244306063
-
Deficiency in the glycerol channel Fps1p confers increased freeze tolerance to yeast cells: Application of the fps1delta mutant to frozen dough technology
-
Izawa, S., Ikeda, K., Maeta, K., & Inoue, Y., (2004). Deficiency in the glycerol channel Fps1p confers increased freeze tolerance to yeast cells:Application of the fps1delta mutant to frozen dough technology. Applied Microbiology and Biotechnology, 66, 303–305.10.1007/s00253-004-1688-1
-
(2004)
Applied Microbiology and Biotechnology
, vol.66
, pp. 303-305
-
-
Izawa, S.1
Ikeda, K.2
Maeta, K.3
Inoue, Y.4
-
55
-
-
7044282883
-
Intracellular glycerol influences resistance to freeze stress in Saccharomyces cerevisiae: Analysis of a quadruple mutant in glycerol dehydrogenase genes and glycerol-enriched cells
-
Izawa, S., Sato, M., Yokoigawa, K., & Inoue, Y., (2004). Intracellular glycerol influences resistance to freeze stress in Saccharomyces cerevisiae:Analysis of a quadruple mutant in glycerol dehydrogenase genes and glycerol-enriched cells. Applied Microbiology and Biotechnology, 66, 108–114.10.1007/s00253-004-1624-4
-
(2004)
Applied Microbiology and Biotechnology
, vol.66
, pp. 108-114
-
-
Izawa, S.1
Sato, M.2
Yokoigawa, K.3
Inoue, Y.4
-
56
-
-
84923021733
-
Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae
-
Jakočiūnas, T., Bonde, I., Herrgård, M., Harrison, S. J., Kristensen, M., Pedersen, L. E., … Keasling, J. D., (2015). Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae. Metabolic Engineering, 28, 213–222.
-
(2015)
Metabolic Engineering
, vol.28
, pp. 213-222
-
-
Jakočiūnas, T.1
Bonde, I.2
Herrgård, M.3
Harrison, S.J.4
Kristensen, M.5
Pedersen, L.E.6
Keasling, J.D.7
-
57
-
-
0036267740
-
Identification of genes that are associated with DNA repeats in prokaryotes
-
Jansen, R., Embden, J. D. A. v., Gaastra, W., & Schouls, L. M., (2002). Identification of genes that are associated with DNA repeats in prokaryotes. Molecular Microbiology, 43, 1565–1575.10.1046/j.1365-2958.2002.02839.x
-
(2002)
Molecular Microbiology
, vol.43
, pp. 1565-1575
-
-
Jansen, R.1
Embden, J.D.A.V.2
Gaastra, W.3
Schouls, L.M.4
-
58
-
-
0035929121
-
Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA
-
Ji, Y., Zhang, B., Van, S. F., Warren, P., Woodnutt, G., Burnham, M. K., & Rosenberg, M., (2001). Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA. Science, 293, 2266–2269.10.1126/science.1063566
-
(2001)
Science
, vol.293
, pp. 2266-2269
-
-
Ji, Y.1
Zhang, B.2
Van, S.F.3
Warren, P.4
Woodnutt, G.5
Burnham, M.K.6
Rosenberg, M.7
-
59
-
-
84874608929
-
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
-
Jiang, W., Bikard, D., Cox, D., Zhang, F., & Marraffini, L. A., (2013a). RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nature Biotechnology, 31, 233–239.10.1038/nbt.2508
-
(2013)
Nature Biotechnology
, vol.31
, pp. 233-239
-
-
Jiang, W.1
Bikard, D.2
Cox, D.3
Zhang, F.4
Marraffini, L.A.5
-
60
-
-
84886926151
-
Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in arabidopsis, tobacco, sorghum and rice
-
Jiang, W., Zhou, H., Bi, H., Fromm, M., Yang, B., & Weeks, D. P., (2013b). Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in arabidopsis, tobacco, sorghum and rice. Nucleic Acids Research.
-
(2013)
Nucleic Acids Research
-
-
Jiang, W.1
Zhou, H.2
Bi, H.3
Fromm, M.4
Yang, B.5
Weeks, D.P.6
-
61
-
-
84925355124
-
Multigene editing in the Escherichia coli genome via the CRISPR-Cas9 system
-
Jiang, Y., Chen, B., Duan, C., Sun, B., Yang, J., & Yang, S., (2015). Multigene editing in the Escherichia coli genome via the CRISPR-Cas9 system. Applied and Environmental Microbiology, 81, 2506–2514.10.1128/AEM.04023-14
-
(2015)
Applied and Environmental Microbiology
, vol.81
, pp. 2506-2514
-
-
Jiang, Y.1
Chen, B.2
Duan, C.3
Sun, B.4
Yang, J.5
Yang, S.6
-
62
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E., (2012). A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science, 337, 816–821.10.1126/science.1225829
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
63
-
-
84876567971
-
RNA-programmed genome editing in human cells
-
Jinek, M., East, A., Cheng, A., Lin, S., Ma, E., Doudna, J., 2013. RNA-programmed genome editing in human cells. eLife, 2.
-
(2013)
eLife
, vol.2
-
-
Jinek, M.1
East, A.2
Cheng, A.3
Lin, S.4
Ma, E.5
Doudna, J.6
-
64
-
-
84925507413
-
Metabolic engineering for improved production of ethanol by Corynebacterium glutamicum
-
Jojima, T., Noburyu, R., Sasaki, M., Tajima, T., Suda, M., Yukawa, H., & Inui, M., (2015). Metabolic engineering for improved production of ethanol by Corynebacterium glutamicum. Applied Microbiology and Biotechnology, 99, 1165–1172.10.1007/s00253-014-6223-4
-
(2015)
Applied Microbiology and Biotechnology
, vol.99
, pp. 1165-1172
-
-
Jojima, T.1
Noburyu, R.2
Sasaki, M.3
Tajima, T.4
Suda, M.5
Yukawa, H.6
Inui, M.7
-
65
-
-
84856536610
-
Small RNA RyhB as a potential tool used for metabolic engineering in Escherichia coli
-
Kang, Z., Wang, X., Li, Y., Wang, Q., & Qi, Q., (2012). Small RNA RyhB as a potential tool used for metabolic engineering in Escherichia coli. Biotechnology Letters, 34, 527–531.10.1007/s10529-011-0794-2
-
(2012)
Biotechnology Letters
, vol.34
, pp. 527-531
-
-
Kang, Z.1
Wang, X.2
Li, Y.3
Wang, Q.4
Qi, Q.5
-
66
-
-
84943662980
-
Metabolic engineering toward enhanced LC-PUFA biosynthesis in Nannochloropsis oceanica: Overexpression of endogenous Δ12 desaturase driven by stress-inducible promoter leads to enhanced deposition of polyunsaturated fatty acids in TAG
-
Kaye, Y., Grundman, O., Leu, S., Zarka, A., Zorin, B., Didi-Cohen, S., … Boussiba, S., (2015). Metabolic engineering toward enhanced LC-PUFA biosynthesis in Nannochloropsis oceanica:Overexpression of endogenous Δ12 desaturase driven by stress-inducible promoter leads to enhanced deposition of polyunsaturated fatty acids in TAG. Algal Research, 11, 387–398.10.1016/j.algal.2015.05.003
-
(2015)
Algal Research
, vol.11
, pp. 387-398
-
-
Kaye, Y.1
Grundman, O.2
Leu, S.3
Zarka, A.4
Zorin, B.5
Didi-Cohen, S.6
Boussiba, S.7
-
67
-
-
84867660750
-
Inhibitory cross-talk upon introduction of a new metabolic pathway into an existing metabolic network
-
Kim, J., & Copley, S. D., (2012). Inhibitory cross-talk upon introduction of a new metabolic pathway into an existing metabolic network. Proceedings of the National academy of Sciences of the United States of America, 109, E2856–E2864.10.1073/pnas.1208509109
-
(2012)
Proceedings of the National academy of Sciences of the United States of America
, vol.109
, pp. E2856-E2864
-
-
Kim, J.1
Copley, S.D.2
-
68
-
-
84922471043
-
Engineering the supply chain for protein production/secretion in yeasts and mammalian cells
-
Klein, T., Niklas, J., & Heinzle, E., (2015). Engineering the supply chain for protein production/secretion in yeasts and mammalian cells. Journal of Industrial Microbiology and Biotechnology, 42, 453–464.10.1007/s10295-014-1569-2
-
(2015)
Journal of Industrial Microbiology and Biotechnology
, vol.42
, pp. 453-464
-
-
Klein, T.1
Niklas, J.2
Heinzle, E.3
-
69
-
-
0038514074
-
Engineering metabolism and product formation in Corynebacterium glutamicum by coordinated gene overexpression
-
Koffas, M. A., Jung, G. Y., & Stephanopoulos, G., (2003). Engineering metabolism and product formation in Corynebacterium glutamicum by coordinated gene overexpression. Metabolic Engineering, 5, 32–41.10.1016/S1096-7176(03)00002-8
-
(2003)
Metabolic Engineering
, vol.5
, pp. 32-41
-
-
Koffas, M.A.1
Jung, G.Y.2
Stephanopoulos, G.3
-
70
-
-
84923640664
-
Evolution of adaptive immunity from transposable elements combined with innate immune systems
-
Koonin, E. V., & Krupovic, M., (2015). Evolution of adaptive immunity from transposable elements combined with innate immune systems. Nature Reviews Genetics, 16, 184–192.
-
(2015)
Nature Reviews Genetics
, vol.16
, pp. 184-192
-
-
Koonin, E.V.1
Krupovic, M.2
-
71
-
-
84961677939
-
Metabolic engineering
-
Kulkarni, R., (2016). Metabolic engineering. Resonance, 21, 233–237.10.1007/s12045-016-0318-4
-
(2016)
Resonance
, vol.21
, pp. 233-237
-
-
Kulkarni, R.1
-
72
-
-
79960040198
-
Metabolic engineering of bacteria
-
Kumar, R. R., & Prasad, S., (2011). Metabolic engineering of bacteria. Indian Journal of Microbiology, 51, 403–409.10.1007/s12088-011-0172-8
-
(2011)
Indian Journal of Microbiology
, vol.51
, pp. 403-409
-
-
Kumar, R.R.1
Prasad, S.2
-
73
-
-
52649115929
-
Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coli
-
Lee, J. Y., Sung, B. H., Yu, B. J., Lee, J. H., Lee, S. H., Kim, M. S., … Kim, S. C., (2008). Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coli. Nucleic Acids Research, 36, e102–e102.10.1093/nar/gkn449
-
(2008)
Nucleic Acids Research
, vol.36
, pp. e102
-
-
Lee, J.Y.1
Sung, B.H.2
Yu, B.J.3
Lee, J.H.4
Lee, S.H.5
Kim, M.S.6
Kim, S.C.7
-
74
-
-
85017350101
-
Targeted gene deletion using DNA-free RNA-guided Cas9 nuclease accelerates adaptation of CHO cells to suspension culture
-
Lee, N., Shin, J., Park, J. H., Lee, G. M., Cho, S., & Cho, B.-K., (2016). Targeted gene deletion using DNA-free RNA-guided Cas9 nuclease accelerates adaptation of CHO cells to suspension culture. ACS Synthetic Biology, 5, 1211–1219.
-
(2016)
ACS Synthetic Biology
, vol.5
, pp. 1211-1219
-
-
Lee, N.1
Shin, J.2
Park, J.H.3
Lee, G.M.4
Cho, S.5
Cho, B.-K.6
-
75
-
-
28344455644
-
Biotechnological production of amino acids and derivatives: Current status and prospects
-
Leuchtenberger, W., Huthmacher, K., & Drauz, K., (2005). Biotechnological production of amino acids and derivatives:Current status and prospects. Applied Microbiology and Biotechnology, 69, 1–8.10.1007/s00253-005-0155-y
-
(2005)
Applied Microbiology and Biotechnology
, vol.69
, pp. 1-8
-
-
Leuchtenberger, W.1
Huthmacher, K.2
Drauz, K.3
-
76
-
-
84883819602
-
Heritable gene targeting in the mouse and rat using a CRISPR-Cas system
-
Li, D., Qiu, Z., Shao, Y., Chen, Y., Guan, Y., Liu, M., … Lu, X., (2013). Heritable gene targeting in the mouse and rat using a CRISPR-Cas system. Nature Biotechnology, 31, 681–683.10.1038/nbt.2661
-
(2013)
Nature Biotechnology
, vol.31
, pp. 681-683
-
-
Li, D.1
Qiu, Z.2
Shao, Y.3
Chen, Y.4
Guan, Y.5
Liu, M.6
Lu, X.7
-
77
-
-
84883779087
-
Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems
-
Li, W., Teng, F., Li, T., & Zhou, Q., (2013). Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nature Biotechnology, 31, 684–686.10.1038/nbt.2652
-
(2013)
Nature Biotechnology
, vol.31
, pp. 684-686
-
-
Li, W.1
Teng, F.2
Li, T.3
Zhou, Q.4
-
78
-
-
84937538704
-
Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing
-
Li, Y., Lin, Z., Huang, C., Zhang, Y., Wang, Z., Tang, Y.-J., … Zhao, X., (2015). Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing. Metabolic Engineering, 31, 13–21.10.1016/j.ymben.2015.06.006
-
(2015)
Metabolic Engineering
, vol.31
, pp. 13-21
-
-
Li, Y.1
Lin, Z.2
Huang, C.3
Zhang, Y.4
Wang, Z.5
Tang, Y.-J.6
Zhao, X.7
-
79
-
-
84894321885
-
Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system
-
Liang, Z., Zhang, K., Chen, K., & Gao, C., (2014). Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system. Journal of Genetics and Genomics, 41, 63–68.10.1016/j.jgg.2013.12.001
-
(2014)
Journal of Genetics and Genomics
, vol.41
, pp. 63-68
-
-
Liang, Z.1
Zhang, K.2
Chen, K.3
Gao, C.4
-
80
-
-
84930618439
-
CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
-
Liang, P., Xu, Y., Zhang, X., Ding, C., Huang, R., Zhang, Z., … Li, Y., (2015). CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes. Protein and Cell, 1–10.
-
(2015)
Protein and Cell
, pp. 1-10
-
-
Liang, P.1
Xu, Y.2
Zhang, X.3
Ding, C.4
Huang, R.5
Zhang, Z.6
Li, Y.7
-
81
-
-
84929134273
-
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
-
Liao, J., Karnik, R., Gu, H., Ziller, M. J., Clement, K., Tsankov, A. M., … Galonska, C., (2015). Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Nature Genetics, 47, 469–478.10.1038/ng.3258
-
(2015)
Nature Genetics
, vol.47
, pp. 469-478
-
-
Liao, J.1
Karnik, R.2
Gu, H.3
Ziller, M.J.4
Clement, K.5
Tsankov, A.M.6
Galonska, C.7
-
82
-
-
79960084127
-
Subtyping Salmonella enterica serovar enteritidis Isolates from different sources by using sequence typing based on virulence genes and clustered regularly interspaced short palindromic repeats (CRISPRs)
-
Liu, F., Kariyawasam, S., Jayarao, B. M., Barrangou, R., Gerner-Smidt, P., Ribot, E. M., … Dudley, E. G., (2011). Subtyping Salmonella enterica serovar enteritidis Isolates from different sources by using sequence typing based on virulence genes and clustered regularly interspaced short palindromic repeats (CRISPRs). Applied and Environmental Microbiology, 77, 4520–4526.10.1128/AEM.00468-11
-
(2011)
Applied and Environmental Microbiology
, vol.77
, pp. 4520-4526
-
-
Liu, F.1
Kariyawasam, S.2
Jayarao, B.M.3
Barrangou, R.4
Gerner-Smidt, P.5
Ribot, E.M.6
Dudley, E.G.7
-
83
-
-
84954190659
-
Overcoming substrate limitations for improved production of ethylene in E. coli
-
Lynch, S., Eckert, C., Yu, J., Gill, R., & Maness, P.-C., (2016). Overcoming substrate limitations for improved production of ethylene in E. coli. Biotechnology for Biofuels, 9, 1–10.
-
(2016)
Biotechnology for Biofuels
, vol.9
, pp. 1-10
-
-
Lynch, S.1
Eckert, C.2
Yu, J.3
Gill, R.4
Maness, P.-C.5
-
84
-
-
84924033943
-
Genome engineering for improved recombinant protein expression in Escherichia coli
-
Mahalik, S., Sharma, A. K., & Mukherjee, K. J., (2014). Genome engineering for improved recombinant protein expression in Escherichia coli. Microbial Cell Factories, 13, 1–13.
-
(2014)
Microbial Cell Factories
, vol.13
, pp. 1-13
-
-
Mahalik, S.1
Sharma, A.K.2
Mukherjee, K.J.3
-
85
-
-
79960554003
-
Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems
-
Makarova, K. S., Aravind, L., Wolf, Y. I., & Koonin, E. V., (2011). Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems. Biology Direct, 6, 38–38.10.1186/1745-6150-6-38
-
(2011)
Biology Direct
, vol.6
, pp. 38
-
-
Makarova, K.S.1
Aravind, L.2
Wolf, Y.I.3
Koonin, E.V.4
-
86
-
-
79956157571
-
Evolution and classification of the CRISPR-Cas systems
-
Makarova, K. S., Haft, D. H., Barrangou, R., Brouns, S. J. J., Charpentier, E., Horvath, P., … Koonin, E. V., (2011). Evolution and classification of the CRISPR-Cas systems. Nature Reviews Microbiology, 9, 467–477.10.1038/nrmicro2577
-
(2011)
Nature Reviews Microbiology
, vol.9
, pp. 467-477
-
-
Makarova, K.S.1
Haft, D.H.2
Barrangou, R.3
Brouns, S.J.J.4
Charpentier, E.5
Horvath, P.6
Koonin, E.V.7
-
87
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P., Yang, L., Esvelt, K. M., Aach, J., Guell, M., DiCarlo, J. E., … Church, G. M., (2013). RNA-guided human genome engineering via Cas9. Science, 339, 823–826.10.1126/science.1232033
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Church, G.M.7
-
88
-
-
84891932593
-
Application of the CRISPR–cas system for efficient genome engineering in plants
-
Mao, Y., Zhang, H., Xu, N., Zhang, B., Gou, F., & Zhu, J.-K., (2013). Application of the CRISPR–cas system for efficient genome engineering in plants. Molecular Plant, 6, 2008–2011.10.1093/mp/sst121
-
(2013)
Molecular Plant
, vol.6
, pp. 2008-2011
-
-
Mao, Y.1
Zhang, H.2
Xu, N.3
Zhang, B.4
Gou, F.5
Zhu, J.-K.6
-
89
-
-
77249170201
-
CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea
-
Marraffini, L. A., & Sontheimer, E. J., (2010). CRISPR interference:RNA-directed adaptive immunity in bacteria and archaea. Nature Reviews Genetics, 11, 181–190.10.1038/nrg2749
-
(2010)
Nature Reviews Genetics
, vol.11
, pp. 181-190
-
-
Marraffini, L.A.1
Sontheimer, E.J.2
-
90
-
-
0038391517
-
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
-
Martin, V. J., Pitera, D. J., Withers, S. T., Newman, J. D., & Keasling, J. D., (2003). Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nature Biotechnology, 21, 796–802.10.1038/nbt833
-
(2003)
Nature Biotechnology
, vol.21
, pp. 796-802
-
-
Martin, V.J.1
Pitera, D.J.2
Withers, S.T.3
Newman, J.D.4
Keasling, J.D.5
-
91
-
-
84948778772
-
Metabolic engineering of Pichia pastoris to produce ricinoleic acid, a hydroxy fatty acid of industrial importance
-
Meesapyodsuk, D., Chen, Y., Ng, S. H., Chen, J., & Qiu, X., (2015). Metabolic engineering of Pichia pastoris to produce ricinoleic acid, a hydroxy fatty acid of industrial importance. Journal of Lipid Research, 56, 2102–2109.10.1194/jlr.M060954
-
(2015)
Journal of Lipid Research
, vol.56
, pp. 2102-2109
-
-
Meesapyodsuk, D.1
Chen, Y.2
Ng, S.H.3
Chen, J.4
Qiu, X.5
-
92
-
-
84929276488
-
Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus
-
Merkle, F. T., Neuhausser, W. M., Santos, D., Valen, E., Gagnon, J. A., Maas, K., … Eggan, K., (2015). Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus. Cell Reports, 11, 875–883.10.1016/j.celrep.2015.04.007
-
(2015)
Cell Reports
, vol.11
, pp. 875-883
-
-
Merkle, F.T.1
Neuhausser, W.M.2
Santos, D.3
Valen, E.4
Gagnon, J.A.5
Maas, K.6
Eggan, K.7
-
93
-
-
84885180177
-
Targeted mutagenesis in rice using CRISPR-Cas system
-
Miao, J., Guo, D., Zhang, J., Huang, Q., Qin, G., Zhang, X., … Qu, L.-J., (2013). Targeted mutagenesis in rice using CRISPR-Cas system. Cell Research, 23, 1233.10.1038/cr.2013.123
-
(2013)
Cell Research
, vol.23
, pp. 1233
-
-
Miao, J.1
Guo, D.2
Zhang, J.3
Huang, Q.4
Qin, G.5
Zhang, X.6
Qu, L.-J.7
-
94
-
-
84938551854
-
Comparison of CRISPR/Cas9 expression constructs for efficient targeted mutagenesis in rice
-
Mikami, M., Toki, S., & Endo, M., (2015). Comparison of CRISPR/Cas9 expression constructs for efficient targeted mutagenesis in rice. Plant Molecular Biology, 88, 561–572.10.1007/s11103-015-0342-x
-
(2015)
Plant Molecular Biology
, vol.88
, pp. 561-572
-
-
Mikami, M.1
Toki, S.2
Endo, M.3
-
95
-
-
16844378680
-
Efficient discrimination within a Corynebacterium diphtheriae epidemic clonal group by a novel macroarray-based method
-
Mokrousov, I., Narvskaya, O., Limeschenko, E., & Vyazovaya, A., (2005). Efficient discrimination within a Corynebacterium diphtheriae epidemic clonal group by a novel macroarray-based method. Journal of Clinical Microbiology, 43, 1662–1668.10.1128/JCM.43.4.1662-1668.2005
-
(2005)
Journal of Clinical Microbiology
, vol.43
, pp. 1662-1668
-
-
Mokrousov, I.1
Narvskaya, O.2
Limeschenko, E.3
Vyazovaya, A.4
-
96
-
-
84938798387
-
Metabolic changes of recombinant Escherichia coli BL21 (DE3) during overexpression of recombinant human interferon beta in HCDC
-
Morowvat, M. H., Babaeipour, V., Rajabi-Memari, H., & Vahidi, H., (2014). Metabolic changes of recombinant Escherichia coli BL21 (DE3) during overexpression of recombinant human interferon beta in HCDC. Int J Biosci, 4, 131–138.
-
(2014)
Int J Biosci
, vol.4
, pp. 131-138
-
-
Morowvat, M.H.1
Babaeipour, V.2
Rajabi-Memari, H.3
Vahidi, H.4
-
97
-
-
84894562109
-
Overexpression of recombinant human beta interferon (rhINF-β) in periplasmic space of Escherichia coli
-
Morowvat, M. H., Babaeipour, V., Rajabi-Memari, H., Vahidi, H., & Maghsoudi, N., (2014). Overexpression of recombinant human beta interferon (rhINF-β) in periplasmic space of Escherichia coli. Iran. J. Pharm. Res., 13, 151–160.
-
(2014)
Iran. J. Pharm. Res.
, vol.13
, pp. 151-160
-
-
Morowvat, M.H.1
Babaeipour, V.2
Rajabi-Memari, H.3
Vahidi, H.4
Maghsoudi, N.5
-
98
-
-
84873596341
-
Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs
-
Na, D., Yoo, S. M., Chung, H., Park, H., Park, J. H., & Lee, S. Y., (2013). Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs. Nature Biotechnology, 31, 170–174.10.1038/nbt.2461
-
(2013)
Nature Biotechnology
, vol.31
, pp. 170-174
-
-
Na, D.1
Yoo, S.M.2
Chung, H.3
Park, H.4
Park, J.H.5
Lee, S.Y.6
-
99
-
-
33845667323
-
Paired termini stabilize antisense RNAs and enhance conditional gene silencing in Escherichia coli
-
Nakashima, N., Tamura, T., & Good, L., (2006). Paired termini stabilize antisense RNAs and enhance conditional gene silencing in Escherichia coli. Nucleic Acids Research, 34, e138.10.1093/nar/gkl697
-
(2006)
Nucleic Acids Research
, vol.34
, pp. e138
-
-
Nakashima, N.1
Tamura, T.2
Good, L.3
-
100
-
-
84883828590
-
Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
-
Nekrasov, V., Staskawicz, B., Weigel, D., Jones, J. D., & Kamoun, S., (2013). Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nature Biotechnology, 31, 691–693.10.1038/nbt.2655
-
(2013)
Nature Biotechnology
, vol.31
, pp. 691-693
-
-
Nekrasov, V.1
Staskawicz, B.2
Weigel, D.3
Jones, J.D.4
Kamoun, S.5
-
101
-
-
84858443042
-
Quercetin treatment changes fluxes in the primary metabolism and increases culture longevity and recombinant α1-antitrypsin production in human AGE1.HN cells
-
Niklas, J., Nonnenmacher, Y., Rose, T., Sandig, V., & Heinzle, E., (2011). Quercetin treatment changes fluxes in the primary metabolism and increases culture longevity and recombinant α1-antitrypsin production in human AGE1.HN cells. Applied Microbiology and Biotechnology, 94, 57–67.
-
(2011)
Applied Microbiology and Biotechnology
, vol.94
, pp. 57-67
-
-
Niklas, J.1
Nonnenmacher, Y.2
Rose, T.3
Sandig, V.4
Heinzle, E.5
-
102
-
-
84961654631
-
Increasing pentose phosphate pathway flux enhances recombinant protein production in Pichia pastoris
-
Nocon, J., Steiger, M., Mairinger, T., Hohlweg, J., Rußmayer, H., Hann, S., … Mattanovich, D., (2016). Increasing pentose phosphate pathway flux enhances recombinant protein production in Pichia pastoris. Applied Microbiology and Biotechnology, 1–9.
-
(2016)
Applied Microbiology and Biotechnology
, pp. 1-9
-
-
Nocon, J.1
Steiger, M.2
Mairinger, T.3
Hohlweg, J.4
Rußmayer, H.5
Hann, S.6
Mattanovich, D.7
-
103
-
-
84964315717
-
CRISPR-Cas9-assisted recombineering in Lactobacillus reuteri
-
Oh, J.-H., & van Pijkeren, J.-P., (2014). CRISPR-Cas9-assisted recombineering in Lactobacillus reuteri. Nucleic Acids Research, 42, e131.10.1093/nar/gku623
-
(2014)
Nucleic Acids Research
, vol.42
, pp. e131
-
-
Oh, J.-H.1
van Pijkeren, J.-P.2
-
104
-
-
84884155038
-
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
-
Pattanayak, V., Lin, S., Guilinger, J. P., Ma, E., Doudna, J. A., & Liu, D. R., (2013). High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nature Biotechnology, 31, 839–843.10.1038/nbt.2673
-
(2013)
Nature Biotechnology
, vol.31
, pp. 839-843
-
-
Pattanayak, V.1
Lin, S.2
Guilinger, J.P.3
Ma, E.4
Doudna, J.A.5
Liu, D.R.6
-
105
-
-
84929593887
-
Codon compression algorithms for saturation mutagenesis
-
Pines, G., Pines, A., Garst, A. D., Zeitoun, R. I., Lynch, S. A., & Gill, R. T., (2015). Codon compression algorithms for saturation mutagenesis. ACS Synthetic Biology, 4, 604–614.10.1021/sb500282v
-
(2015)
ACS Synthetic Biology
, vol.4
, pp. 604-614
-
-
Pines, G.1
Pines, A.2
Garst, A.D.3
Zeitoun, R.I.4
Lynch, S.A.5
Gill, R.T.6
-
106
-
-
84904654756
-
Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila
-
Port, F., Chen, H.-M., Lee, T., & Bullock, S. L., (2014). Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila. Proceedings of the National Academy of Sciences, 111, E2967–E2976.10.1073/pnas.1405500111
-
(2014)
Proceedings of the National Academy of Sciences
, vol.111
, pp. E2967-E2976
-
-
Port, F.1
Chen, H.-M.2
Lee, T.3
Bullock, S.L.4
-
107
-
-
84874687019
-
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
-
Qi, L. S., Larson, M. H., Gilbert, L. A., Doudna, J. A., Weissman, J. S., Arkin, A. P., & Lim, W. A., (2013). Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell, 152, 1173–1183.10.1016/j.cell.2013.02.022
-
(2013)
Cell
, vol.152
, pp. 1173-1183
-
-
Qi, L.S.1
Larson, M.H.2
Gilbert, L.A.3
Doudna, J.A.4
Weissman, J.S.5
Arkin, A.P.6
Lim, W.A.7
-
108
-
-
84973100704
-
Studying the features of 57 confirmed CRISPR loci in 29 strains of Escherichia coli
-
Rahmatabadi, S. S., Nezafat, N., Negahdaripour, M., Hajighahramani, N., Morowvat, M. H., & Ghasemi, Y., (2016). Studying the features of 57 confirmed CRISPR loci in 29 strains of Escherichia coli. Journal of Basic Microbiology, 56, 1–9.
-
(2016)
Journal of Basic Microbiology
, vol.56
, pp. 1-9
-
-
Rahmatabadi, S.S.1
Nezafat, N.2
Negahdaripour, M.3
Hajighahramani, N.4
Morowvat, M.H.5
Ghasemi, Y.6
-
109
-
-
84942079449
-
The CRISPR-Cas immune system: Biology, mechanisms and applications
-
Rath, D., Amlinger, L., Rath, A., & Lundgren, M., (2015). The CRISPR-Cas immune system:Biology, mechanisms and applications. Biochimie, 117, 119–128.10.1016/j.biochi.2015.03.025
-
(2015)
Biochimie
, vol.117
, pp. 119-128
-
-
Rath, D.1
Amlinger, L.2
Rath, A.3
Lundgren, M.4
-
110
-
-
84862601628
-
Isobutyraldehyde production from Escherichia coli by removing aldehyde reductase activity
-
Rodriguez, G. M., & Atsumi, S., (2012). Isobutyraldehyde production from Escherichia coli by removing aldehyde reductase activity. Microbial Cell Factories, 11, 90.10.1186/1475-2859-11-90
-
(2012)
Microbial Cell Factories
, vol.11
, pp. 90
-
-
Rodriguez, G.M.1
Atsumi, S.2
-
111
-
-
84928485570
-
High-yield hydrogen production from biomass by in vitro metabolic engineering: Mixed sugars coutilization and kinetic modeling
-
Rollin, J. A., del Campo, J. M., Myung, S., Sun, F., You, C., Bakovic, A., … Adams, M. W., (2015). High-yield hydrogen production from biomass by in vitro metabolic engineering:Mixed sugars coutilization and kinetic modeling. Proceedings of the National Academy of Sciences, 112, 4964–4969.10.1073/pnas.1417719112
-
(2015)
Proceedings of the National Academy of Sciences
, vol.112
, pp. 4964-4969
-
-
Rollin, J.A.1
del Campo, J.M.2
Myung, S.3
Sun, F.4
You, C.5
Bakovic, A.6
Adams, M.W.7
-
112
-
-
84957989754
-
Improving expression of recombinant human IGF-1 using IGF-1R knockout CHO cell lines
-
Romand, S., Jostock, T., Fornaro, M., Schmidt, J., Ritter, A., Wilms, B., & Laux, H., (2016). Improving expression of recombinant human IGF-1 using IGF-1R knockout CHO cell lines. Biotechnology and Bioengineering, 113, 1094–1101.10.1002/bit.25877
-
(2016)
Biotechnology and Bioengineering
, vol.113
, pp. 1094-1101
-
-
Romand, S.1
Jostock, T.2
Fornaro, M.3
Schmidt, J.4
Ritter, A.5
Wilms, B.6
Laux, H.7
-
113
-
-
1542293809
-
Genetic engineering of a zeaxanthin-rich potato by antisense inactivation and co-suppression of carotenoid epoxidation
-
Römer, S., Lübeck, J., Kauder, F., Steiger, S., Adomat, C., & Sandmann, G., (2002). Genetic engineering of a zeaxanthin-rich potato by antisense inactivation and co-suppression of carotenoid epoxidation. Metabolic Engineering, 4, 263–272.10.1006/mben.2002.0234
-
(2002)
Metabolic Engineering
, vol.4
, pp. 263-272
-
-
Römer, S.1
Lübeck, J.2
Kauder, F.3
Steiger, S.4
Adomat, C.5
Sandmann, G.6
-
114
-
-
84935430511
-
Designing a bacterial biosensor for detection of mercury in water solutions
-
Roointan, A., Shabab, N., Karimi, J., Rahmani, A., Alikhani, M. Y., & Saidijam, M., (2015). Designing a bacterial biosensor for detection of mercury in water solutions. Turkish Journal of Biology, 39, 550–555.10.3906/biy-1411-49
-
(2015)
Turkish Journal of Biology
, vol.39
, pp. 550-555
-
-
Roointan, A.1
Shabab, N.2
Karimi, J.3
Rahmani, A.4
Alikhani, M.Y.5
Saidijam, M.6
-
115
-
-
84885336337
-
Structure of the CRISPR interference complex CSM reveals key similarities with cascade
-
Rouillon, C., Zhou, M., Zhang, J., Politis, A., Beilsten-Edmands, V., Cannone, G., … White, M. F., (2013). Structure of the CRISPR interference complex CSM reveals key similarities with cascade. Molecular Cell, 52, 124–134.10.1016/j.molcel.2013.08.020
-
(2013)
Molecular Cell
, vol.52
, pp. 124-134
-
-
Rouillon, C.1
Zhou, M.2
Zhang, J.3
Politis, A.4
Beilsten-Edmands, V.5
Cannone, G.6
White, M.F.7
-
116
-
-
84911871184
-
Selection of chromosomal DNA libraries using a multiplex CRISPR system
-
3, e03703
-
Ryan, O. W., Skerker, J. M., Maurer, M. J., Li, X., Tsai, J. C., Poddar, S., … Cate, J. H. D., 2014. Selection of chromosomal DNA libraries using a multiplex CRISPR system. eLife 3, e03703.
-
(2014)
eLife
-
-
Ryan, O.W.1
Skerker, J.M.2
Maurer, M.J.3
Li, X.4
Tsai, J.C.5
Poddar, S.6
Cate, J.H.D.7
-
117
-
-
84900314611
-
CRISPR-Cas systems for editing, regulating and targeting genomes
-
Sander, J. D., & Joung, J. K., (2014). CRISPR-Cas systems for editing, regulating and targeting genomes. Nature Biotechnology, 32, 347–355.10.1038/nbt.2842
-
(2014)
Nature Biotechnology
, vol.32
, pp. 347-355
-
-
Sander, J.D.1
Joung, J.K.2
-
118
-
-
84862827747
-
Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch mode
-
Scalcinati, G., Knuf, C., Partow, S., Chen, Y., Maury, J., Schalk, M., … Siewers, V., (2012). Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch mode. Metabolic Engineering, 14, 91–103.10.1016/j.ymben.2012.01.007
-
(2012)
Metabolic Engineering
, vol.14
, pp. 91-103
-
-
Scalcinati, G.1
Knuf, C.2
Partow, S.3
Chen, Y.4
Maury, J.5
Schalk, M.6
Siewers, V.7
-
119
-
-
84940184252
-
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
-
Schumann, K., Lin, S., Boyer, E., Simeonov, D. R., Subramaniam, M., Gate, R. E., … Doudna, J. A., (2015). Generation of knock-in primary human T cells using Cas9 ribonucleoproteins. Proceedings of the National Academy of Sciences, 112, 10437–10442.10.1073/pnas.1512503112
-
(2015)
Proceedings of the National Academy of Sciences
, vol.112
, pp. 10437-10442
-
-
Schumann, K.1
Lin, S.2
Boyer, E.3
Simeonov, D.R.4
Subramaniam, M.5
Gate, R.E.6
Doudna, J.A.7
-
120
-
-
84888372954
-
A simplified and efficient germline-specific CRISPR/Cas9 system for Drosophila genomic engineering
-
Sebo, Z. L., Lee, H. B., Peng, Y., & Guo, Y., (2014). A simplified and efficient germline-specific CRISPR/Cas9 system for Drosophila genomic engineering. Fly, 8, 52–57.10.4161/fly.26828
-
(2014)
Fly
, vol.8
, pp. 52-57
-
-
Sebo, Z.L.1
Lee, H.B.2
Peng, Y.3
Guo, Y.4
-
121
-
-
85042815594
-
Targeted genome modification of crop plants using a CRISPR-Cas system
-
Shan, Q., Wang, Y., Li, J., Zhang, Y., Chen, K., Liang, Z., … Qiu, J.-L., (2013). Targeted genome modification of crop plants using a CRISPR-Cas system. Nature Biotechnology, 31, 686–688.10.1038/nbt.2650
-
(2013)
Nature Biotechnology
, vol.31
, pp. 686-688
-
-
Shan, Q.1
Wang, Y.2
Li, J.3
Zhang, Y.4
Chen, K.5
Liang, Z.6
Qiu, J.-L.7
-
122
-
-
84897954175
-
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
-
Shen, B., Zhang, W., Zhang, J., Zhou, J., Wang, J., Chen, L., … Skarnes, W. C., (2014). Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects. Nature Methods, 11, 399–402.10.1038/nmeth.2857
-
(2014)
Nature Methods
, vol.11
, pp. 399-402
-
-
Shen, B.1
Zhang, W.2
Zhang, J.3
Zhou, J.4
Wang, J.5
Chen, L.6
Skarnes, W.C.7
-
123
-
-
79953779608
-
Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system
-
Sinkunas, T., Gasiunas, G., Fremaux, C., Barrangou, R., Horvath, P., & Siksnys, V., (2011). Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system. The EMBO Journal, 30, 1335–1342.10.1038/emboj.2011.41
-
(2011)
The EMBO Journal
, vol.30
, pp. 1335-1342
-
-
Sinkunas, T.1
Gasiunas, G.2
Fremaux, C.3
Barrangou, R.4
Horvath, P.5
Siksnys, V.6
-
124
-
-
84869102255
-
A dynamic metabolite valve for the control of central carbon metabolism
-
Solomon, K. V., Sanders, T. M., & Prather, K. L., (2012). A dynamic metabolite valve for the control of central carbon metabolism. Metabolic Engineering, 14, 661–671.10.1016/j.ymben.2012.08.006
-
(2012)
Metabolic Engineering
, vol.14
, pp. 661-671
-
-
Solomon, K.V.1
Sanders, T.M.2
Prather, K.L.3
-
126
-
-
84927920113
-
CRISPR–Cas system enables fast and simple genome editing of industrial Saccharomyces cerevisiae strains
-
Stovicek, V., Borodina, I., & Forster, J., (2015). CRISPR–Cas system enables fast and simple genome editing of industrial Saccharomyces cerevisiae strains. Metabolic Engineering Communications, 2, 13–22.10.1016/j.meteno.2015.03.001
-
(2015)
Metabolic Engineering Communications
, vol.2
, pp. 13-22
-
-
Stovicek, V.1
Borodina, I.2
Forster, J.3
-
127
-
-
84860433123
-
CRISPR interference directs strand specific spacer acquisition
-
Swarts, D. C., Mosterd, C., van Passel, M. W. J., & Brouns, S. J. J., (2012). CRISPR interference directs strand specific spacer acquisition. PLoS ONE, 7, e35888.10.1371/journal.pone.0035888
-
(2012)
PLoS ONE
, vol.7
, pp. e35888
-
-
Swarts, D.C.1
Mosterd, C.2
van Passel, M.W.J.3
Brouns, S.J.J.4
-
128
-
-
84923186857
-
Off-target assessment of CRISPR-Cas9 guiding RNAs in human iPS and mouse ES cells
-
Tan, E., Li, Y., Del Castillo Velasco-Herrera, M., Yusa, K., & Bradley, A., (2015). Off-target assessment of CRISPR-Cas9 guiding RNAs in human iPS and mouse ES cells. Genesis, 53, 225–236.10.1002/dvg.v53.2
-
(2015)
Genesis
, vol.53
, pp. 225-236
-
-
Tan, E.1
Li, Y.2
Del Castillo Velasco-Herrera, M.3
Yusa, K.4
Bradley, A.5
-
129
-
-
4344698377
-
Using RNAi to improve plant nutritional value: From mechanism to application
-
Tang, G., & Galili, G., (2004). Using RNAi to improve plant nutritional value:From mechanism to application. Trends in Biotechnology, 22, 463–469.10.1016/j.tibtech.2004.07.009
-
(2004)
Trends in Biotechnology
, vol.22
, pp. 463-469
-
-
Tang, G.1
Galili, G.2
-
130
-
-
34748836500
-
RNAi and microRNA: Breakthrough technologies for the improvement of plant nutritional value and metabolic engineering
-
Tang, G., Galili, G., & Zhuang, X., (2007). RNAi and microRNA:Breakthrough technologies for the improvement of plant nutritional value and metabolic engineering. Metabolomics, 3, 357–369.10.1007/s11306-007-0073-3
-
(2007)
Metabolomics
, vol.3
, pp. 357-369
-
-
Tang, G.1
Galili, G.2
Zhuang, X.3
-
131
-
-
0036952087
-
Aquaporin Expression correlates with freeze tolerance in baker’s yeast, and overexpression improves freeze tolerance in industrial strains
-
Tanghe, A., Van Dijck, P., Dumortier, F., Teunissen, A., Hohmann, S., & Thevelein, J. M., (2002). Aquaporin Expression correlates with freeze tolerance in baker’s yeast, and overexpression improves freeze tolerance in industrial strains. Applied and Environmental Microbiology, 68, 5981–5989.10.1128/AEM.68.12.5981-5989.2002
-
(2002)
Applied and Environmental Microbiology
, vol.68
, pp. 5981-5989
-
-
Tanghe, A.1
Van Dijck, P.2
Dumortier, F.3
Teunissen, A.4
Hohmann, S.5
Thevelein, J.M.6
-
132
-
-
79959319829
-
CRISPR-based adaptive immune systems
-
Terns, M. P., & Terns, R. M., (2011). CRISPR-based adaptive immune systems. Current Opinion in Microbiology, 14, 321–327.10.1016/j.mib.2011.03.005
-
(2011)
Current Opinion in Microbiology
, vol.14
, pp. 321-327
-
-
Terns, M.P.1
Terns, R.M.2
-
133
-
-
20544457864
-
Metabolic engineering in the -omics era: Elucidating and modulating regulatory networks
-
Vemuri, G. N., & Aristidou, A. A., (2005). Metabolic engineering in the -omics era:Elucidating and modulating regulatory networks. Microbiology and Molecular Biology Reviews, 69, 197–216.10.1128/MMBR.69.2.197-216.2005
-
(2005)
Microbiology and Molecular Biology Reviews
, vol.69
, pp. 197-216
-
-
Vemuri, G.N.1
Aristidou, A.A.2
-
135
-
-
77952317396
-
Metabolic engineering for ethylene production by inserting the ethylene-forming enzyme gene (efe) at the 16S rDNA sites of Pseudomonas putida KT2440
-
Wang, J.-P., Wu, L.-X., Xu, F., Lv, J., Jin, H.-J., & Chen, S.-F., (2010). Metabolic engineering for ethylene production by inserting the ethylene-forming enzyme gene (efe) at the 16S rDNA sites of Pseudomonas putida KT2440. Bioresource Technology, 101, 6404–6409.10.1016/j.biortech.2010.03.030
-
(2010)
Bioresource Technology
, vol.101
, pp. 6404-6409
-
-
Wang, J.-P.1
Wu, L.-X.2
Xu, F.3
Lv, J.4
Jin, H.-J.5
Chen, S.-F.6
-
136
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-Mediated genome engineering
-
Wang, H., Yang, H., Shivalila, C. S., Dawlaty, M. M., Cheng, A. W., Zhang, F., & Jaenisch, R., (2013). One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-Mediated genome engineering. Cell, 153, 910–918.10.1016/j.cell.2013.04.025
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
137
-
-
33746913914
-
Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for biotechnological production of organic acids and amino acids
-
Wendisch, V. F., Bott, M., & Eikmanns, B. J., (2006). Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for biotechnological production of organic acids and amino acids. Current Opinion in Microbiology, 9, 268–274.10.1016/j.mib.2006.03.001
-
(2006)
Current Opinion in Microbiology
, vol.9
, pp. 268-274
-
-
Wendisch, V.F.1
Bott, M.2
Eikmanns, B.J.3
-
138
-
-
84921602939
-
Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos
-
Whitworth, K. M., Lee, K., Benne, J. A., Beaton, B. P., Spate, L. D., Murphy, S. L., … Prather, R. S., (2014). Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos. Biology of Reproduction, 91, 1–13.
-
(2014)
Biology of Reproduction
, vol.91
, pp. 1-13
-
-
Whitworth, K.M.1
Lee, K.2
Benne, J.A.3
Beaton, B.P.4
Spate, L.D.5
Murphy, S.L.6
Prather, R.S.7
-
139
-
-
84857097177
-
RNA-guided genetic silencing systems in bacteria and archaea
-
Wiedenheft, B., Sternberg, S. H., & Doudna, J. A., (2012). RNA-guided genetic silencing systems in bacteria and archaea. Nature, 482, 331–338.10.1038/nature10886
-
(2012)
Nature
, vol.482
, pp. 331-338
-
-
Wiedenheft, B.1
Sternberg, S.H.2
Doudna, J.A.3
-
140
-
-
8344271026
-
Production of recombinant protein therapeutics in cultivated mammalian cells
-
Wurm, F. M., (2004). Production of recombinant protein therapeutics in cultivated mammalian cells. Nature Biotechnology, 22, 1393–1398.10.1038/nbt1026
-
(2004)
Nature Biotechnology
, vol.22
, pp. 1393-1398
-
-
Wurm, F.M.1
-
141
-
-
84884962826
-
RNA-guided genome editing in plants using a CRISPR–Cas system
-
Xie, K., & Yang, Y., (2013). RNA-guided genome editing in plants using a CRISPR–Cas system. Molecular Plant, 6, 1975–1983.10.1093/mp/sst119
-
(2013)
Molecular Plant
, vol.6
, pp. 1975-1983
-
-
Xie, K.1
Yang, Y.2
-
142
-
-
84928212425
-
Antisense suppression of LOX3 gene expression in rice endosperm enhances seed longevity
-
Xu, H., Wei, Y., Zhu, Y., Lian, L., Xie, H., Cai, Q., … Xie, H., (2015). Antisense suppression of LOX3 gene expression in rice endosperm enhances seed longevity. Plant Biotechnology Journal, 13, 526–539.10.1111/pbi.12277
-
(2015)
Plant Biotechnology Journal
, vol.13
, pp. 526-539
-
-
Xu, H.1
Wei, Y.2
Zhu, Y.3
Lian, L.4
Xie, H.5
Cai, Q.6
Xie, H.7
-
143
-
-
84946402066
-
Efficient gene-targeting in rat embryonic stem cells by CRISPR/Cas and generation of human kynurenine aminotransferase II (KAT II) knock-in rat
-
Yamamoto, S., Ooshima, Y., Nakata, M., Yano, T., Nishimura, N., Nishigaki, R., … Takeyama, M., (2015). Efficient gene-targeting in rat embryonic stem cells by CRISPR/Cas and generation of human kynurenine aminotransferase II (KAT II) knock-in rat. Transgenic Research, 24, 991–1001.10.1007/s11248-015-9909-1
-
(2015)
Transgenic Research
, vol.24
, pp. 991-1001
-
-
Yamamoto, S.1
Ooshima, Y.2
Nakata, M.3
Yano, T.4
Nishimura, N.5
Nishigaki, R.6
Takeyama, M.7
-
144
-
-
84966948762
-
Applications of CRISPR-Cas9 mediated genome engineering
-
Yang, X., (2015). Applications of CRISPR-Cas9 mediated genome engineering. Military Medical Research, 2, 1027.10.1186/s40779-015-0038-1
-
(2015)
Military Medical Research
, vol.2
, pp. 1027
-
-
Yang, X.1
-
145
-
-
84928159353
-
Regulating malonyl-CoA metabolism via synthetic antisense RNAs for enhanced biosynthesis of natural products
-
Yang, Y., Lin, Y., Li, L., Linhardt, R. J., & Yan, Y., (2015). Regulating malonyl-CoA metabolism via synthetic antisense RNAs for enhanced biosynthesis of natural products. Metabolic Engineering, 29, 217–226.10.1016/j.ymben.2015.03.018
-
(2015)
Metabolic Engineering
, vol.29
, pp. 217-226
-
-
Yang, Y.1
Lin, Y.2
Li, L.3
Linhardt, R.J.4
Yan, Y.5
-
146
-
-
84883419083
-
Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli
-
Yoo, S. M., Na, D., & Lee, S. Y., (2013). Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli. Nature Protocols, 8, 1694–1707.10.1038/nprot.2013.105
-
(2013)
Nature Protocols
, vol.8
, pp. 1694-1707
-
-
Yoo, S.M.1
Na, D.2
Lee, S.Y.3
-
147
-
-
84861639567
-
Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli
-
Yosef, I., Goren, M. G., & Qimron, U., (2012). Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli. Nucleic Acids Research, 40, 5569–5576.10.1093/nar/gks216
-
(2012)
Nucleic Acids Research
, vol.40
, pp. 5569-5576
-
-
Yosef, I.1
Goren, M.G.2
Qimron, U.3
-
148
-
-
23044450772
-
Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice
-
Yu, X. X., Murray, S. F., Pandey, S. K., Booten, S. L., Bao, D., Song, X. Z., … Monia, B. P., (2005). Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice. Hepatology, 42, 362–371.10.1002/(ISSN)1527-3350
-
(2005)
Hepatology
, vol.42
, pp. 362-371
-
-
Yu, X.X.1
Murray, S.F.2
Pandey, S.K.3
Booten, S.L.4
Bao, D.5
Song, X.Z.6
Monia, B.P.7
-
149
-
-
84952672368
-
Metabolic engineering of Saccharomyces cerevisiae for the overproduction of short branched-chain fatty acids
-
Yu, A.-Q., Pratomo Juwono, N. K., Foo, J. L., Leong, S. S. J., & Chang, M. W., (2016). Metabolic engineering of Saccharomyces cerevisiae for the overproduction of short branched-chain fatty acids. Metabolic Engineering, 34, 36–43.10.1016/j.ymben.2015.12.005
-
(2016)
Metabolic Engineering
, vol.34
, pp. 36-43
-
-
Yu, A.-Q.1
Pratomo Juwono, N.K.2
Foo, J.L.3
Leong, S.S.J.4
Chang, M.W.5
-
150
-
-
84946831928
-
Metabolic engineering of Escherichia coli for the biosynthesis of 2-pyrrolidone
-
Zhang, J., Kao, E., Wang, G., Baidoo, E. E. K., Chen, M., & Keasling, J. D., (2016). Metabolic engineering of Escherichia coli for the biosynthesis of 2-pyrrolidone. Metabolic Engineering Communications, 3, 1–7.10.1016/j.meteno.2015.11.001
-
(2016)
Metabolic Engineering Communications
, vol.3
, pp. 1-7
-
-
Zhang, J.1
Kao, E.2
Wang, G.3
Baidoo, E.E.K.4
Chen, M.5
Keasling, J.D.6
-
151
-
-
84930928815
-
A CRISPR/Cas-mediated selection-free knockin strategy in human embryonic stem cells
-
Zhu, Z., Verma, N., González, F., Shi, Z.-D., & Huangfu, D., 2015. A CRISPR/Cas-mediated selection-free knockin strategy in human embryonic stem cells. Stem Cell Reports, 4, 1103–1111.
-
(2015)
Stem Cell Reports
, vol.4
, pp. 1103-1111
-
-
Zhu, Z.1
Verma, N.2
González, F.3
Shi, Z.-D.4
Huangfu, D.5
|