Regulating malonyl-CoA metabolism via synthetic antisense RNAs for enhanced biosynthesis of natural products

Metabolic Engineering

Volumn 29, Issue , 2015, Pages 217-226

  Yang, Yaping ^a   Lin, Yuheng ^a   Li, Lingyun ^b   Linhardt, Robert J ^b   Yan, Yajun ^a  

^a University of Georgia   (United States)

^b Research Rensselaer Polytechnic Institute   (United States)

Author keywords

4 hydroxycoumarin; Antisense RNA; Fatty acid biosynthesis; Malonyl CoA; Naringenin; Resveratrol

Indexed keywords

BIOCHEMISTRY; BIOPOLYMERS; BIOSYNTHESIS; ESCHERICHIA COLI; FLAVONOIDS; GENE EXPRESSION; GENES; METABOLIC ENGINEERING; METABOLISM; MOLECULES; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RESVERATROL; RNA;

4-HYDROXYCOUMARIN; ANTISENSE RNA; FATTY ACID BIOSYNTHESIS; MALONYL-COA; NARINGENIN;

FATTY ACIDS;

4 HYDROXYCOUMARIN; COMPLEMENTARY RNA; MALONYL COENZYME A; NARINGENIN; NATURAL PRODUCT; RESVERATROL; ACYL CARRIER PROTEIN MALONYLTRANSFERASE; ESCHERICHIA COLI PROTEIN; FABD PROTEIN, E COLI; FATTY ACID SYNTHASE;

ARTICLE; BACTERIAL GENE; BIOSYNTHESIS; CELL VIABILITY; DOWN REGULATION; ENZYME METABOLISM; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; FLUORESCENCE ANALYSIS; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ESCHERICHIA COLI;

ACYL-CARRIER PROTEIN S-MALONYLTRANSFERASE; ESCHERICHIA COLI PROTEINS; FATTY ACID SYNTHASE, TYPE II; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALONYL COENZYME A; RNA, ANTISENSE;

EID: 84928159353     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.03.018     Document Type: Article

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