Targeted germline modifications in rats using CRISPR/Cas9 and spermatogonial stem cells

Cell Reports

Volumn 10, Issue 11, 2015, Pages 1828-1835

  Chapman, Karen M ^a   Medrano, Gerardo A ^a   Jaichander, Priscilla ^a   Chaudhary, Jaideep ^a   Waits, Alexandra E ^a   Nobrega, Marcelo A ^c   Hotaling, James M ^d   Ober, Carole ^c   Hamra, Kent F ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE; EPIDERMAL GROWTH FACTOR RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; EPSTI1 GENE; ERBB3 GENE; FRAMESHIFT MUTATION; GENE; GENE EDITING; GENE TARGETING; GENETIC ENGINEERING; GENETIC SELECTION; GERMLINE MUTATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEMINIFEROUS TUBULE; SPERMATOGENESIS; SPERMATOGONIAL STEM CELL; SPERMATOGONIUM; STEM CELL; STEM CELL CULTURE; STEM CELL TRANSPLANTATION; TESTIS WEIGHT; ANIMAL; CELL CULTURE; FEMALE; GENETICS; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT; TRANSPLANTATION;

RATTUS;

ANIMALS; CELLS, CULTURED; CRISPR-CAS SYSTEMS; FEMALE; GENE TARGETING; GERM-LINE MUTATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ERBB-3; SPERMATOGONIA;

EID: 84925662286     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.02.040     Document Type: Article

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