A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish

Developmental Cell

Volumn 32, Issue 6, 2015, Pages 756-764

  Ablain, Julien ^a   Durand, Ellen M ^a   Yang, Song ^a   Zhou, Yi ^a,b   Zon, Leonard I ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUIDE RNA; HEME; MESSENGER RNA; TRANSCRIPTION FACTOR GATA 1; P53 PROTEIN, ZEBRAFISH; PHOTOPROTEIN; PROTEIN P53; RED FLUORESCENT PROTEIN; ZEBRAFISH PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BLACKFAN DIAMOND ANEMIA; CAS9 GENE; CELL LINEAGE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; EMBRYO; ERYTHROCYTE; ERYTHROID PRECURSOR CELL; EXPRESSION VECTOR; GATA1 GENE; GENE; GENE DISRUPTION; GENE EXPRESSION; GENE INACTIVATION; GENE TARGETING; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MOSAICISM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; STABLE EXPRESSION; TISSUE SPECIFICITY; TUMOR SUPPRESSOR GENE; UROD GENE; YQUEM GENE; ZEBRA FISH; ANIMAL; CYTOLOGY; DISEASE MODEL; EMBRYOLOGY; GENE VECTOR; GENETIC ENGINEERING; GENETICS; PROCEDURES;

DANIO RERIO;

ANEMIA, DIAMOND-BLACKFAN; ANIMALS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; DISEASE MODELS, ANIMAL; ERYTHROCYTES; GENE KNOCKOUT TECHNIQUES; GENETIC ENGINEERING; GENETIC VECTORS; LUMINESCENT PROTEINS; PROMOTER REGIONS, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84925351121     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2015.01.032     Document Type: Article

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