Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

Hepatology

Volumn 42, Issue 2, 2005, Pages 362-371

  Yu, Xing Xian ^a   Murray, Susan F ^a   Pandey, Sanjay K ^a   Booten, Sheri L ^a   Bao, Dingjiu ^a   Song, Xiu Zhen ^a   Kelly, Susan ^a   Chen, Songyuan ^a   McKay, Robert ^a   Monia, Brett P ^a   Bhanot, Sanjay ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; ADENOSINE TRIPHOSPHATE CITRATE LYASE; ANTISENSE OLIGONUCLEOTIDE; DIACYLGLYCEROL ACYLTRANSFERASE; DIACYLGLYCEROL ACYLTRANSFERASE 1; DIACYLGLYCEROL ACYLTRANSFERASE 2; FAS ANTIGEN; FATTY ACID; GLYCEROL KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; PROTEIN ACC1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; FATTY ACID OXIDATION; FATTY LIVER; GENE EXPRESSION; GLUCOSE METABOLISM; HYPERLIPIDEMIA; LIPID DIET; LIPID METABOLISM; LIPOGENESIS; LIPOPROTEIN BLOOD LEVEL; METABOLIC SYNDROME X; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ACYLTRANSFERASES; ANIMALS; BLOOD GLUCOSE; DIACYLGLYCEROL O-ACYLTRANSFERASE; FATTY ACIDS; FATTY LIVER; HEPATOCYTES; HYPERLIPIDEMIAS; LIPIDS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; OLIGONUCLEOTIDES, ANTISENSE; OXIDATION-REDUCTION; SKIN; TRIGLYCERIDES;

EID: 23044450772     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20783     Document Type: Article

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