메뉴 건너뛰기




Volumn 70, Issue 8, 1996, Pages 5203-5212

Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CAPSID PROTEIN; ENVELOPE PROTEIN; MEMBRANE PROTEIN; VIRUS RNA;

EID: 0029996016     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.8.5203-5212.1996     Document Type: Article
Times cited : (113)

References (53)
  • 2
    • 0022972284 scopus 로고
    • Inhibition of vesicular stomatitis virus protein synthesis and infection by sequence-specific oligodeoxyribonucleoside methylphosphonates
    • Agris, C. H., K. R. Blake, P. S. Miller, M. P. Reddy, and P. O. P. Ts'O. 1986 Inhibition of vesicular stomatitis virus protein synthesis and infection by sequence-specific oligodeoxyribonucleoside methylphosphonates. Biochemistry 25:6268-6275.
    • (1986) Biochemistry , vol.25 , pp. 6268-6275
    • Agris, C.H.1    Blake, K.R.2    Miller, P.S.3    Reddy, M.P.4    Ts'O, P.O.P.5
  • 3
    • 0029156656 scopus 로고
    • Specific inhibition of hepatitis C viral gene expression by antisense phosphorothioate oligodeoxynucleotides
    • Alt, M., R. Renz, P. H. Hofschneider, G. Paumgartner, and W. H. Caselmann. 1995. Specific inhibition of hepatitis C viral gene expression by antisense phosphorothioate oligodeoxynucleotides. Hepatology 22:707-717.
    • (1995) Hepatology , vol.22 , pp. 707-717
    • Alt, M.1    Renz, R.2    Hofschneider, P.H.3    Paumgartner, G.4    Caselmann, W.H.5
  • 4
    • 0024377134 scopus 로고
    • Detection of antibody to hepatitis C virus in prospeclively followed transfusion recipients with acute and chronic non-A, non-B hepatitis
    • Alter, H. J., R. H. Purcell, J. W. Shih, J. C. Melpolder, M. Houghton, and Q.-L. Choo. 1989. Detection of antibody to hepatitis C virus in prospeclively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N. Engl. J. Med. 321:1494-1500.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1494-1500
    • Alter, H.J.1    Purcell, R.H.2    Shih, J.W.3    Melpolder, J.C.4    Houghton, M.5    Choo, Q.-L.6
  • 5
    • 0027216834 scopus 로고
    • Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region
    • Azad, R. F., V. B. Driver, K. Tanaka. R. M. Crooke, and K. P. Anderson. 1993. Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region. Antimicrob. Agents Chemother. 37:1945-1954.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 1945-1954
    • Azad, R.F.1    Driver, V.B.2    Tanaka, K.3    Crooke, R.M.4    Anderson, K.P.5
  • 7
    • 0027092897 scopus 로고
    • Cationic lipids enhance cellular uptake and activity of phosphorothioate antiscnse oligonucleotidcs
    • Bennett, C. F., M,-Y. Chiang, H. Chan, J. E. Shoemaker, and C. Mirabelli. 1992, Cationic lipids enhance cellular uptake and activity of phosphorothioate antiscnse oligonucleotidcs. Mol. Pharmacol. 41:1023-1033.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 1023-1033
    • Bennett, C.F.1    Chiang, M.-Y.2    Chan, H.3    Shoemaker, J.E.4    Mirabelli, C.5
  • 8
    • 0026674719 scopus 로고
    • Secondary structure of the 5' nontranslatcd regions of hepatitis C virus and pestivirus genomic RNAs
    • Brown, E. A., H. Zhang, L.-H. Ping, and S. M. Lemon. 1992. Secondary structure of the 5' nontranslatcd regions of hepatitis C virus and pestivirus genomic RNAs. Nucleic Acids Res. 20:5041-5045.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5041-5045
    • Brown, E.A.1    Zhang, H.2    Ping, L.-H.3    Lemon, S.M.4
  • 10
    • 0026728652 scopus 로고
    • Sequence analysis of the 5́ noncoding region of hepatitis C virus
    • Bukh, J., R. H. Purcell, and R. H. Miller. 1992. Sequence analysis of the 5́ noncoding region of hepatitis C virus. Proc. Natl. Acad. Sci. USA 89:4942-4946.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4942-4946
    • Bukh, J.1    Purcell, R.H.2    Miller, R.H.3
  • 11
    • 0027214322 scopus 로고
    • At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide
    • Bukh, J., R. H. Purcell, and R. H. Miller. 1993. At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide. Proc. Natl. Acad. Sci. USA 90:8234-8238.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8234-8238
    • Bukh, J.1    Purcell, R.H.2    Miller, R.H.3
  • 12
    • 0019321638 scopus 로고
    • Purification, subunit structure, and serological analysis of calf thymus ribonuclease H1
    • Busen, W. 1980. Purification, subunit structure, and serological analysis of calf thymus ribonuclease H1. J. Biol. Chem. 255:9434-9443.
    • (1980) J. Biol. Chem. , vol.255 , pp. 9434-9443
    • Busen, W.1
  • 13
    • 0024407164 scopus 로고
    • Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides
    • Cazenave, C, C. A. Stein, N. Loreau, N. T. Thuong, and L. M. Neckers. 1989. Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides. Nucleic Acids Res. 17:4255-4261.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 4255-4261
    • Cazenave, C.1    Stein, C.A.2    Loreau, N.3    Thuong, N.T.4    Neckers, L.M.5
  • 14
    • 0026052924 scopus 로고
    • Antisense oligonucleotides inhibit ICAM-1 expression by two distinct mechanisms
    • Chiang, M-Y., H. Chan, M. A. Zounes, S. M. Freier, W. F. Lima, and C. F. Bennett. 1991. Antisense oligonucleotides inhibit ICAM-1 expression by two distinct mechanisms. J. Biol. Chem. 266:18162-18171.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18162-18171
    • Chiang, M.-Y.1    Chan, H.2    Zounes, M.A.3    Freier, S.M.4    Lima, W.F.5    Bennett, C.F.6
  • 15
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo, Q.-L., G. Kuo, A. J. Weiner, L. R. Overby, D. W. Bradly, and M. Houghton. 1989. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244:359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.-L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradly, D.W.5    Houghton, M.6
  • 17
    • 0027399409 scopus 로고
    • In vitro evaluation of phosphorothinate oligonucleotides targeted to the E2 mRNA of papilloraavirus: Potential treatment for genital warts
    • Cowsert, L. M., M. C. Fox, G. Zon, and C. K. Mirabelli. 1993. In vitro evaluation of phosphorothinate oligonucleotides targeted to the E2 mRNA of papilloraavirus: potential treatment for genital warts. Antimicrob. Agents Chemother. 37:171-177.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 171-177
    • Cowsert, L.M.1    Fox, M.C.2    Zon, G.3    Mirabelli, C.K.4
  • 18
    • 0026721173 scopus 로고
    • Therapeutic applications of oligonucleotides
    • Crooke, S. T. 1992. Therapeutic applications of oligonucleotides. Annu. Rev, Pharmacol. Toxicol. 32:329-376.
    • (1992) Annu. Rev, Pharmacol. Toxicol. , vol.32 , pp. 329-376
    • Crooke, S.T.1
  • 20
    • 0028916028 scopus 로고
    • Progress in antisense therapeutics
    • Crooke, S. T. 1995. Progress in antisense therapeutics. Hematol. Pathol. 9: 59-72.
    • (1995) Hematol. Pathol. , vol.9 , pp. 59-72
    • Crooke, S.T.1
  • 21
    • 0024296810 scopus 로고
    • Complementary oligodeoxynucleotide mediated inhibition of tobacco mosaic virus RNA translation in vitro
    • Crum, C, J. D. Johnson, A. Nelson, and D. Roth. 1988. Complementary oligodeoxynucleotide mediated inhibition of tobacco mosaic virus RNA translation in vitro. Nucleic Acids Res. 16:4569-4581.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 4569-4581
    • Crum, C.1    Johnson, J.D.2    Nelson, A.3    Roth, D.4
  • 22
    • 8944222925 scopus 로고    scopus 로고
    • Personal communication
    • Cummins, L. Personal communication.
    • Cummins, L.1
  • 23
    • 0029077840 scopus 로고
    • Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity
    • Cummins, I, L., S. R. Owens, L. M. Risen, E. A. Lesnik, S. M. Freier, D. McGee, C. J. Guinosso, and P. D. Cook. 1995. Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity. Nucleic Acids Res. 23:2019-2024.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2019-2024
    • Cummins, I.L.1    Owens, S.R.2    Risen, L.M.3    Lesnik, E.A.4    Freier, S.M.5    McGee, D.6    Guinosso, C.J.7    Cook, P.D.8
  • 25
    • 0028292570 scopus 로고
    • Inhibition of protein kinase C-α expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters
    • Dean, N. M., R. McKay, T. P. Condon, and C. F. Bennett. 1994. Inhibition of protein kinase C-α expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters. J. Biol. Chem. 269:16416-16424.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16416-16424
    • Dean, N.M.1    McKay, R.2    Condon, T.P.3    Bennett, C.F.4
  • 27
    • 0029083209 scopus 로고
    • Anatomy of the poliovirus internal ribosome entry site
    • P. Sarnow (ed.), Springer-Verlag, Berlin
    • Ehrenfeld, E., and B. L. Semler. 1995. Anatomy of the poliovirus internal ribosome entry site, p. 65-83. In P. Sarnow (ed.), Cap-independent translation. Springer-Verlag, Berlin.
    • (1995) Cap-independent Translation , pp. 65-83
    • Ehrenfeld, E.1    Semler, B.L.2
  • 28
    • 0002326455 scopus 로고
    • Hybridization: Considerations affecting antisense drugs
    • S. T. Crooke and B. Lebleu (ed.), CRC Press. Boca Raton, Fia.
    • Freier, S. M. 1993. Hybridization: considerations affecting antisense drugs, p. 67-82. In S. T. Crooke and B. Lebleu (ed.), Antisense research and applications. CRC Press. Boca Raton, Fia.
    • (1993) Antisense Research and Applications , pp. 67-82
    • Freier, S.M.1
  • 30
    • 0026048056 scopus 로고
    • Effect of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus
    • Hoke, G., K. Draper, S. Freier, C. Gonzalez, V. B. Driver, M. C. Zounes, and D. J. Ecker. 1991. Effect of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus. Nucleic Acids Res. 19:5743-5748.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 5743-5748
    • Hoke, G.1    Draper, K.2    Freier, S.3    Gonzalez, C.4    Driver, V.B.5    Zounes, M.C.6    Ecker, D.J.7
  • 31
    • 0023650861 scopus 로고
    • Sequence-dependent hydrolysis of RNA using modified Oligonucleotide splints and RNase H
    • Inoue, H., Y. Hayase, S. Iwai, and E. Ohtsuka. 1987. Sequence-dependent hydrolysis of RNA using modified Oligonucleotide splints and RNase H. FEBS Lett. 215:327-330.
    • (1987) FEBS Lett. , vol.215 , pp. 327-330
    • Inoue, H.1    Hayase, Y.2    Iwai, S.3    Ohtsuka, E.4
  • 32
    • 0027479864 scopus 로고
    • Uniformly modified 2′-deoxy-2′-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets
    • Kawasaki, A. M., M. D. Casper, S. M. Freier, E. A. Lesnik, M. C. Zounes, L. L. Cummins, C. Gonzalez, and P. D. Cook. 1993. Uniformly modified 2′-deoxy-2′-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J. Med. Chem. 36:831-841.
    • (1993) J. Med. Chem. , vol.36 , pp. 831-841
    • Kawasaki, A.M.1    Casper, M.D.2    Freier, S.M.3    Lesnik, E.A.4    Zounes, M.C.5    Cummins, L.L.6    Gonzalez, C.7    Cook, P.D.8
  • 33
    • 0007684104 scopus 로고
    • Site specificity of the inhibitory effects of oligo(nucleo-side methylphlosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4
    • Kulka, M., C. C. Smith, L. Aurelian, R. Fishelevich, K. Meade, P. Miller, and P. O. P. Ts'O. 1989. Site specificity of the inhibitory effects of oligo(nucleo-side methylphlosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4. Proc. Natl. Acad. Sci. USA 86:6868-6872.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 6868-6872
    • Kulka, M.1    Smith, C.C.2    Aurelian, L.3    Fishelevich, R.4    Meade, K.5    Miller, P.6    Ts'O, P.O.P.7
  • 34
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
    • (1970) Nature (London) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 35
    • 0027381917 scopus 로고
    • Mapping the 5′ and 3′ ends of Tetrahymena thermophila mRNAs using RNA ligase mediated amplification of cDNA ends (RLM-RACE)
    • Liu, X., and M. A. Gorovsky. 1993. Mapping the 5′ and 3′ ends of Tetrahymena thermophila mRNAs using RNA ligase mediated amplification of cDNA ends (RLM-RACE). Nucleic Acids Res. 21:4954-4960.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4954-4960
    • Liu, X.1    Gorovsky, M.A.2
  • 36
    • 0025883162 scopus 로고
    • Internal initiation of translation mediated by the 5′ leader of a cellular mRNA
    • Macejak, D. G., and P. Sarnow. 1991. Internal initiation of translation mediated by the 5′ leader of a cellular mRNA. Nature (London) 353:90-94.
    • (1991) Nature (London) , vol.353 , pp. 90-94
    • Macejak, D.G.1    Sarnow, P.2
  • 38
    • 0029099305 scopus 로고
    • Ein neuer Zugang zu 2′-O-alkylribonucleosiden und Eigenschaften deren Oligonucleotide
    • Martin, P. 1995. Ein neuer Zugang zu 2′-O-alkylribonucleosiden und Eigenschaften deren Oligonucleotide. Helv. Chim. Acta 78:486-504.
    • (1995) Helv. Chim. Acta , vol.78 , pp. 486-504
    • Martin, P.1
  • 39
    • 0026774939 scopus 로고
    • Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides
    • Monia, B. P., J. F. Johnston, D. J. Ecker, M. A. Zounes, W. F. Lima, and S. M. Freier. 1992. Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides. J. Biol. Chem. 267:19954-19962.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19954-19962
    • Monia, B.P.1    Johnston, J.F.2    Ecker, D.J.3    Zounes, M.A.4    Lima, W.F.5    Freier, S.M.6
  • 41
    • 0026784990 scopus 로고
    • Homeotic gene antennapedia mRNA contains 5′-noncoding sequences that confer translational initiation by internal ribosome binding
    • Oh, S. K., M. P. Scott, and P. Sarnow. 1992. Homeotic gene antennapedia mRNA contains 5′-noncoding sequences that confer translational initiation by internal ribosome binding. Genes Dev. 6:1643-1653.
    • (1992) Genes Dev. , vol.6 , pp. 1643-1653
    • Oh, S.K.1    Scott, M.P.2    Sarnow, P.3
  • 43
    • 0024519705 scopus 로고
    • Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetra-biotinylated derivatives: Novel probes that are resistant to degradation by RNA or DNA specific nucleases
    • Sproat, B. S., A. L. Lanmond, B. Beijer, P. Neuner, and U. Ryder. 1989. Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetra-biotinylated derivatives: novel probes that are resistant to degradation by RNA or DNA specific nucleases. Nucleic Acids Res. 17:3373-3386.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 3373-3386
    • Sproat, B.S.1    Lanmond, A.L.2    Beijer, B.3    Neuner, P.4    Ryder, U.5
  • 44
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
    • Stein, C. A., and Y.-C. Cheng. 1993. Antisense oligonucleotides as therapeutic agents - is the bullet really magical? Science 261:1004-1012.
    • (1993) Science , vol.261 , pp. 1004-1012
    • Stein, C.A.1    Cheng, Y.-C.2
  • 45
    • 0026513651 scopus 로고
    • Internal ribosome entry site within hepatitis C virus RNA
    • Tsukiyama-Kohara, K., N. Iizuka, M. Kohara, and A. Nomoto. 1992. Internal ribosome entry site within hepatitis C virus RNA. J. Virol. 66:1476-1483.
    • (1992) J. Virol. , vol.66 , pp. 1476-1483
    • Tsukiyama-Kohara, K.1    Iizuka, N.2    Kohara, M.3    Nomoto, A.4
  • 46
    • 0027619017 scopus 로고
    • Immortalization of differentiated human hepatocytes by a combination of a viral vector and collagen gel culture
    • Ueno, T., T. Miyamura, I. Saito, and K. Mizuno. 1993. Immortalization of differentiated human hepatocytes by a combination of a viral vector and collagen gel culture. Hum. Cell 6:125-135.
    • (1993) Hum. Cell , vol.6 , pp. 125-135
    • Ueno, T.1    Miyamura, T.2    Saito, I.3    Mizuno, K.4
  • 47
    • 11944267365 scopus 로고
    • Antisense oligonucleotides: A new therapeutic principle
    • Uhlmann, E., and A. Peyman. 1990. Antisense oligonucleotides: a new therapeutic principle. Chem. Rev. 90:543-584.
    • (1990) Chem. Rev. , vol.90 , pp. 543-584
    • Uhlmann, E.1    Peyman, A.2
  • 48
    • 0028303251 scopus 로고
    • Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides
    • Wakita, T., and J. R. Wands. 1994. Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides. J. Biol. Chem. 269:14205-14210.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14205-14210
    • Wakita, T.1    Wands, J.R.2
  • 49
    • 0029331431 scopus 로고
    • An RNA pseudoknot is an essential structural element of the internal ribosome entry site located within the hepatitis C virus 5′ noncoding region
    • Wang, C., S.-Y. Le, and A. Siddiqui. 1995. An RNA pseudoknot is an essential structural element of the internal ribosome entry site located within the hepatitis C virus 5′ noncoding region. RNA 1:526-537.
    • (1995) RNA , vol.1 , pp. 526-537
    • Wang, C.1    Le, S.-Y.2    Siddiqui, A.3
  • 50
    • 0027153210 scopus 로고
    • Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism
    • Wang, C., P. Sarnow, and A. Siddiqui. 1993. Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism. J. Virol. 67:3338-3344.
    • (1993) J. Virol. , vol.67 , pp. 3338-3344
    • Wang, C.1    Sarnow, P.2    Siddiqui, A.3
  • 51
    • 0028151477 scopus 로고
    • A conserved helical element is essential for internal initiation of translation of hepatitis C virus RNA
    • Wang, C., P. Sarnow, and A. Siddiqui. 1994. A conserved helical element is essential for internal initiation of translation of hepatitis C virus RNA. J. Virol. 68:7301-7307.
    • (1994) J. Virol. , vol.68 , pp. 7301-7307
    • Wang, C.1    Sarnow, P.2    Siddiqui, A.3
  • 52
    • 0022780091 scopus 로고
    • Oligodeoxynucleotide stability in subcellular extracts and culture media
    • Wickstrom, E. 1986. Oligodeoxynucleotide stability in subcellular extracts and culture media. J. Biochem. Biophys. Methods 13:97-102.
    • (1986) J. Biochem. Biophys. Methods , vol.13 , pp. 97-102
    • Wickstrom, E.1
  • 53
    • 0001477721 scopus 로고
    • Inhibition of replication and expression of human T-cell lymphotropic virus type 111 in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA
    • Zamecnik, P. C., J. Goodchild, Y. Taguchi, and P. S. Sarin. 1986. Inhibition of replication and expression of human T-cell lymphotropic virus type 111 in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA. Proc. Natl. Acad. Sci. USA 83:4143-4146.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 4143-4146
    • Zamecnik, P.C.1    Goodchild, J.2    Taguchi, Y.3    Sarin, P.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.