Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

Nature Biotechnology

Volumn 31, Issue 8, 2013, Pages 681-683

  Li, Dali ^a   Qiu, Zhongwei ^a   Shao, Yanjiao ^a   Chen, Yuting ^a   Guan, Yuting ^a   Liu, Meizhen ^a   Li, Yongmei ^a   Gao, Na ^a   Wang, Liren ^a   Lu, Xiaoling ^b   Zhao, Yongxiang ^b   Liu, Mingyao ^a,c  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b GUANGXI MEDICAL UNIVERSITY   (China)

^c TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT ASSOCIATED PROTEIN; DNA FRAGMENT; DOUBLE STRANDED DNA; ENDONUCLEASE; ETHYLNITROSOUREA; GENOMIC DNA; GUIDE RNA; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MESSENGER RNA; NUCLEASE; UNCLASSIFIED DRUG;

ANIMAL GENETICS; BACTERIUM; CYTOPLASM; DNA CLEAVAGE; DNA END JOINING REPAIR; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; EXPRESSION VECTOR; GENE CLUSTER; GENE DELETION; GENE DISRUPTION; GENE LOCUS; GENE SEQUENCE; GENE TARGETING; GENETIC CONSERVATION; GENETIC ENGINEERING; INDEL MUTATION; KNOCKOUT GENE; KNOCKOUT RAT; LETTER; MAMMAL CELL; MICROINJECTION; MOUSE EMBRYO; MUTATION RATE; NONHUMAN; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROMOTER REGION; ZEBRA FISH;

ANIMALS; BASE SEQUENCE; CASPASE 9; CRISPR-CAS SYSTEMS; GENE TARGETING; INVERTED REPEAT SEQUENCES; MICE; MICE, KNOCKOUT; MUTATION; RATS; RNA; ZEBRAFISH;

EID: 84883819602     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2661     Document Type: Letter

References (17)

1. Garneau, J.E. et al. Nature 468, 67-71 (2010).
2. Makarova, K.S. et al. Nat. Rev. Microbiol. 9, 467-477 (2011).
3. Wiedenheft, B., Sternberg, S.H. & Doudna, J.A. Nature 482, 331-338 (2012).
4. Jinek, M. et al. Science 337, 816-821 (2012).
5. Cong, L. et al. Science 339, 819-823 (2013).
6. Mali, P. et al. Science 339, 823-826 (2013).
7. Hwang, W.Y. et al. Nat. Biotechnol. 31, 227-229 (2013).
8. Jiang, W., Bikard, D., Cox, D., Zhang, F. & Marraffini, L.A. Nat. Biotechnol. 31, 233-239 (2013).
9. Wang, H. et al. Cell 153, 910-918 (2013).
10. Cho, S.W., Kim, S., Kim, J.M. & Kim, J.S. Nat. Biotechnol. 31, 230-232 (2013).
11. Qiu, Z. et al. Nucleic Acids Res. e120 (2013).
12. Sung, Y.H. et al. Nat. Biotechnol. 31, 23-24 (2013).
13. Cui, X. et al. Nat. Biotechnol. 29, 64-67 (2011).
14. Tesson, L. et al. Nat. Biotechnol. 29, 695-696 (2011).
15. Geurts, A.M. et al. Science 325, 433 (2009).
16. Mul, J.D. et al. Obesity (Silver Spring) 20, 612-621 (2012).
17. Fu, Y. et al. Nat. Biotechnol. advance online publication http://www.nature.com/doifinder/10.1038/nbt.2623 (23 June 2013).