메뉴 건너뛰기




Volumn , Issue , 2013, Pages 2617-2640

Potential neuroprotective actions of dietary flavonoids

Author keywords

Flavonoids; Memory; Neurodegeneration; Neuroinflammation; Signaling pathways

Indexed keywords


EID: 84995800321     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-22144-6_71     Document Type: Chapter
Times cited : (6)

References (169)
  • 2
    • 85046909683 scopus 로고    scopus 로고
    • Cell death mechanisms in neurodegeneration
    • 005.001.01 [pii]
    • Jellinger KA (2001) Cell death mechanisms in neurodegeneration. J Cell Mol Med 5(1):1-17, 005.001.01 [pii]
    • (2001) J Cell Mol Med , vol.5 , Issue.1 , pp. 1-17
    • Jellinger, K.A.1
  • 3
    • 0035235476 scopus 로고    scopus 로고
    • Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons
    • Bastianetto S, Zheng WH, Quirion R (2000) Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons. Br J Pharmacol 131(4):711-720
    • (2000) Br J Pharmacol , vol.131 , Issue.4 , pp. 711-720
    • Bastianetto, S.1    Zheng, W.H.2    Quirion, R.3
  • 4
    • 1542605222 scopus 로고    scopus 로고
    • Flavonoids: Antioxidants or signalling molecules?
    • S0891584904000334 [pii]
    • Williams RJ, Spencer JP, Rice-Evans C (2004) Flavonoids: antioxidants or signalling molecules? Free Radic Biol Med 36(7):838-849. doi:10.1016/j.freeradbiomed.2004.01.001, S0891584904000334 [pii]
    • (2004) Free Radic Biol Med , vol.36 , Issue.7 , pp. 838-849
    • Williams, R.J.1    Spencer, J.P.2    Rice-Evans, C.3
  • 5
    • 68149124472 scopus 로고    scopus 로고
    • Dietary phenolics: Chemistry, bioavailability and effects on health
    • Crozier A, Jaganath IB, Clifford MN (2009) Dietary phenolics: chemistry, bioavailability and effects on health. Nat Prod Rep 26(8):1001-1043. doi:10.1039/b802662a
    • (2009) Nat Prod Rep , vol.26 , Issue.8 , pp. 1001-1043
    • Crozier, A.1    Jaganath, I.B.2    Clifford, M.N.3
  • 7
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • 81/1/230S [pii]
    • Manach C, Williamson G, Morand C, Scalbert A, Remesy C (2005) Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 81(1 Suppl):230S-242S, 81/1/230S [pii]
    • (2005) Am J Clin Nutr , vol.81 , Issue.1
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Remesy, C.5
  • 8
    • 13844271387 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
    • 81/1/243S [pii]
    • Williamson G, Manach C (2005) Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am J Clin Nutr 81(1 Suppl):243S-255S, 81/1/243S [pii]
    • (2005) Am J Clin Nutr , vol.81 , Issue.1
    • Williamson, G.1    Manach, C.2
  • 9
    • 70449529433 scopus 로고    scopus 로고
    • Structure and function of the blood-brain barrier
    • S0969-9961(09)00208-3 [pii]
    • Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ (2010) Structure and function of the blood-brain barrier. Neurobiol Dis 37(1):13-25. doi:10.1016/j.nbd.2009.07.030, S0969-9961(09)00208-3 [pii]
    • (2010) Neurobiol Dis , vol.37 , Issue.1 , pp. 13-25
    • Abbott, N.J.1    Patabendige, A.A.2    Dolman, D.E.3    Yusof, S.R.4    Begley, D.J.5
  • 12
    • 0037229942 scopus 로고    scopus 로고
    • Role of P-glycoprotein in pharmacokinetics: Clinical implications
    • Lin JH, Yamazaki M (2003) Role of P-glycoprotein in pharmacokinetics: clinical implications. Clin Pharmacokinet 42(1):59-98
    • (2003) Clin Pharmacokinet , vol.42 , Issue.1 , pp. 59-98
    • Lin, J.H.1    Yamazaki, M.2
  • 13
    • 0031840033 scopus 로고    scopus 로고
    • Determination of naringenin and its glucuronide conjugate in rat plasma and brain tissue by high-performance liquid chromatography
    • Peng HW, Cheng FC, Huang YT, Chen CF, Tsai TH (1998) Determination of naringenin and its glucuronide conjugate in rat plasma and brain tissue by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 714(2)
    • (1998) J Chromatogr B Biomed Sci Appl , vol.714 , Issue.2
    • Peng, H.W.1    Cheng, F.C.2    Huang, Y.T.3    Chen, C.F.4    Tsai, T.H.5
  • 14
    • 0031595920 scopus 로고    scopus 로고
    • Wide distribution of [H-3](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue
    • Suganuma M, Okabe S, Oniyama M, Tada Y, Ito H, Fujiki H (1998) Wide distribution of [H-3](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue. Carcinogenesis 19(10)
    • (1998) Carcinogenesis , vol.19 , Issue.10
    • Suganuma, M.1    Okabe, S.2    Oniyama, M.3    Tada, Y.4    Ito, H.5    Fujiki, H.6
  • 21
    • 77950672438 scopus 로고    scopus 로고
    • Xenobiotic metabolism and berry flavonoid transport across the blood-brain barrier
    • Milbury PE, Kalt W (2010) Xenobiotic metabolism and berry flavonoid transport across the blood-brain barrier. J Agric Food Chem 58(7):3950-3956. doi:10.1021/jf903529m
    • (2010) J Agric Food Chem , vol.58 , Issue.7 , pp. 3950-3956
    • Milbury, P.E.1    Kalt, W.2
  • 22
    • 42149124306 scopus 로고    scopus 로고
    • Food for thought: The role of dietary flavonoids in enhancing human memory, learning and neuro-cognitive performance
    • S0029665108007088 [pii]
    • Spencer JP (2008) Food for thought: the role of dietary flavonoids in enhancing human memory, learning and neuro-cognitive performance. Proc Nutr Soc 67(2):238-252. doi:10.1017/S0029665108007088, S0029665108007088 [pii]
    • (2008) Proc Nutr Soc , vol.67 , Issue.2 , pp. 238-252
    • Spencer, J.P.1
  • 23
    • 52049089562 scopus 로고    scopus 로고
    • Flavonoids: Modulators of brain function?
    • S0007114508965776 [pii]
    • Spencer JP (2008) Flavonoids: modulators of brain function? Br J Nutr 99E(Suppl 1):ES60-ES77. doi:10.1017/S0007114508965776, S0007114508965776 [pii]
    • (2008) Br J Nutr , vol.99E
    • Spencer, J.P.1
  • 25
    • 26844490390 scopus 로고    scopus 로고
    • Soy isoflavones and cognitive function
    • Lee YB, Lee HJ, Sohn HS (2005) Soy isoflavones and cognitive function. J Nutr Biochem 16(11):641-649
    • (2005) J Nutr Biochem , vol.16 , Issue.11 , pp. 641-649
    • Lee, Y.B.1    Lee, H.J.2    Sohn, H.S.3
  • 27
    • 33645390839 scopus 로고    scopus 로고
    • Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: A randomized, double-blind, crossover, placebo-controlled study
    • Casini ML, Marelli G, Papaleo E, Ferrari A, D’ambrosio F, Unfer V (2006) Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: a randomized, double-blind, crossover, placebo-controlled study. Fertil Steril 85(4):972-978
    • (2006) Fertil Steril , vol.85 , Issue.4 , pp. 972-978
    • Casini, M.L.1    Marelli, G.2    Papaleo, E.3    Ferrari, A.4    D’ambrosio, F.5    Unfer, V.6
  • 28
    • 0038240618 scopus 로고    scopus 로고
    • Isoflavones and cognitive function in older women: The SOy and Postmenopausal Health In Aging (SOPHIA) Study
    • Kritz-Silverstein D, Von MD, Barrett-Connor E, Bressel MA (2003) Isoflavones and cognitive function in older women: the SOy and Postmenopausal Health In Aging (SOPHIA) Study. Menopause 10(3):196-202
    • (2003) Menopause , vol.10 , Issue.3 , pp. 196-202
    • Kritz-Silverstein, D.1    Von, M.D.2    Barrett-Connor, E.3    Bressel, M.A.4
  • 29
    • 16244412623 scopus 로고    scopus 로고
    • Cognitive improvement after 6 weeks of soy supplements in postmenopausal women is limited to frontal lobe function
    • File SE, Hartley DE, Elsabagh S, Duffy R, Wiseman H (2005) Cognitive improvement after 6 weeks of soy supplements in postmenopausal women is limited to frontal lobe function. Menopause 12(2):193-201
    • (2005) Menopause , vol.12 , Issue.2 , pp. 193-201
    • File, S.E.1    Hartley, D.E.2    Elsabagh, S.3    Duffy, R.4    Wiseman, H.5
  • 31
    • 3042739688 scopus 로고    scopus 로고
    • Soy isoflavones improve spatial delayed matching-to-place performance and reduce cholinergic neuron loss in elderly male rats
    • Lee YB, Lee HJ, Won MH, Hwang IK, Kang TC, Lee JY, Nam SY, Kim KS, Kim E, Cheon SH, Sohn HS (2004) Soy isoflavones improve spatial delayed matching-to-place performance and reduce cholinergic neuron loss in elderly male rats. J Nutr 134(7): 1827-1831
    • (2004) J Nutr , vol.134 , Issue.7 , pp. 1827-1831
    • Lee, Y.B.1    Lee, H.J.2    Won, M.H.3    Hwang, I.K.4    Kang, T.C.5    Lee, J.Y.6    Nam, S.Y.7    Kim, K.S.8    Kim, E.9    Cheon, S.H.10    Sohn, H.S.11
  • 33
    • 8944226107 scopus 로고    scopus 로고
    • Is there a role for estrogen replacement therapy in the prevention and treatment of dementia?
    • Birge SJ (1996) Is there a role for estrogen replacement therapy in the prevention and treatment of dementia? J Am Geriatr Soc 44(7):865-870
    • (1996) J am Geriatr Soc , vol.44 , Issue.7 , pp. 865-870
    • Birge, S.J.1
  • 34
    • 33644499808 scopus 로고    scopus 로고
    • Estrogen-containing hormone therapy and Alzheimer’s disease risk: Understanding discrepant inferences from observational and experimental research
    • Henderson VW (2006) Estrogen-containing hormone therapy and Alzheimer’s disease risk: understanding discrepant inferences from observational and experimental research. Neuroscience 138(3):1031-1039
    • (2006) Neuroscience , vol.138 , Issue.3 , pp. 1031-1039
    • Henderson, V.W.1
  • 35
    • 0033548238 scopus 로고    scopus 로고
    • Evidence for up-regulation of brain-derived neurotrophic factor mRNA by soy phytoestrogens in the frontal cortex of retired breeder female rats
    • Pan Y, Anthony M, Clarkson TB (1999) Evidence for up-regulation of brain-derived neurotrophic factor mRNA by soy phytoestrogens in the frontal cortex of retired breeder female rats. Neurosci Lett 261(1-2):17-20
    • (1999) Neurosci Lett , vol.261 , Issue.1-2 , pp. 17-20
    • Pan, Y.1    Anthony, M.2    Clarkson, T.B.3
  • 36
    • 0033008049 scopus 로고    scopus 로고
    • Effect of estradiol and soy phytoestrogens on choline acetyltransferase and nerve growth factor mRNAs in the frontal cortex and hippocampus of female rats
    • Pan Y, Anthony M, Clarkson TB (1999) Effect of estradiol and soy phytoestrogens on choline acetyltransferase and nerve growth factor mRNAs in the frontal cortex and hippocampus of female rats. Proc Soc Exp Biol Med 221(2):118-125
    • (1999) Proc Soc Exp Biol Med , vol.221 , Issue.2 , pp. 118-125
    • Pan, Y.1    Anthony, M.2    Clarkson, T.B.3
  • 37
    • 0033568849 scopus 로고    scopus 로고
    • Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation
    • Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ, Bickford PC (1999) Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci 19(18):8114-8121
    • (1999) J Neurosci , vol.19 , Issue.18 , pp. 8114-8121
    • Joseph, J.A.1    Shukitt-Hale, B.2    Denisova, N.A.3    Bielinski, D.4    Martin, A.5    Mc Ewen, J.J.6    Bickford, P.C.7
  • 38
    • 12344311870 scopus 로고    scopus 로고
    • Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats
    • Casadesus G, Shukitt-Hale B, Stellwagen HM, Zhu X, Lee HG, Smith MA, Joseph JA (2004) Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats. Nutr Neurosci 7(5-6):309-316
    • (2004) Nutr Neurosci , vol.7 , Issue.5-6 , pp. 309-316
    • Casadesus, G.1    Shukitt-Hale, B.2    Stellwagen, H.M.3    Zhu, X.4    Lee, H.G.5    Smith, M.A.6    Joseph, J.A.7
  • 39
    • 46749094132 scopus 로고    scopus 로고
    • Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels
    • Williams CM, El Mohsen MA, Vauzour D, Rendeiro C, Butler LT, Ellis JA, Whiteman M, Spencer JP (2008) Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels. Free Radic Biol Med 45(3):295-305
    • (2008) Free Radic Biol Med , vol.45 , Issue.3 , pp. 295-305
    • Williams, C.M.1    El Mohsen, M.A.2    Vauzour, D.3    Rendeiro, C.4    Butler, L.T.5    Ellis, J.A.6    Whiteman, M.7    Spencer, J.P.8
  • 43
    • 32944454490 scopus 로고    scopus 로고
    • Effects of Concord grape juice on cognitive and motor deficits in aging
    • Shukitt-Hale B, Carey A, Simon L, Mark DA, Joseph JA (2006) Effects of Concord grape juice on cognitive and motor deficits in aging. Nutrition 22(3):295-302
    • (2006) Nutrition , vol.22 , Issue.3 , pp. 295-302
    • Shukitt-Hale, B.1    Carey, A.2    Simon, L.3    Mark, D.A.4    Joseph, J.A.5
  • 44
    • 33749494466 scopus 로고    scopus 로고
    • Favorable effects of tea on reducing the cognitive deficits and brain morphological changes in senescence-accelerated mice
    • Chan YC, Hosoda K, Tsai CJ, Yamamoto S, Wang MF (2006) Favorable effects of tea on reducing the cognitive deficits and brain morphological changes in senescence-accelerated mice. J Nutr Sci Vitaminol 52(4):266-273
    • (2006) J Nutr Sci Vitaminol , vol.52 , Issue.4 , pp. 266-273
    • Chan, Y.C.1    Hosoda, K.2    Tsai, C.J.3    Yamamoto, S.4    Wang, M.F.5
  • 46
    • 34548471990 scopus 로고    scopus 로고
    • Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats
    • Pu F, Mishima K, Irie K, Motohashi K, Tanaka Y, Orito K, Egawa T, Kitamura Y, Egashira N, Iwasaki K, Fujiwara M (2007) Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats. J Pharmacol Sci 104(4):329-334
    • (2007) J Pharmacol Sci , vol.104 , Issue.4 , pp. 329-334
    • Pu, F.1    Mishima, K.2    Irie, K.3    Motohashi, K.4    Tanaka, Y.5    Orito, K.6    Egawa, T.7    Kitamura, Y.8    Egashira, N.9    Iwasaki, K.10    Fujiwara, M.11
  • 47
    • 33750832268 scopus 로고    scopus 로고
    • Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory
    • Maher P, Akaishi T, Abe K (2006) Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory. Proc Natl Acad Sci USA 103(44):16568-16573
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.44 , pp. 16568-16573
    • Maher, P.1    Akaishi, T.2    Abe, K.3
  • 50
    • 0031790146 scopus 로고    scopus 로고
    • The pharmacological effects of Gingko Biloba, a plant extract, on the brain of dementia patients in comparison with tacrine
    • Itil TM, Eralp E, Ahmed I, Kunitz A, Itil KZ (1998) The pharmacological effects of Gingko Biloba, a plant extract, on the brain of dementia patients in comparison with tacrine. Psychopharmacology 34:391-396
    • (1998) Psychopharmacology , vol.34 , pp. 391-396
    • Itil, T.M.1    Eralp, E.2    Ahmed, I.3    Kunitz, A.4    Itil, K.Z.5
  • 51
    • 33745673176 scopus 로고    scopus 로고
    • Effects of Ginkgo biloba administered after spatial learning on water maze and radial arm maze performance in young adult rats
    • Shif O, Gillette K, Damkaoutis CM, Carrano C, Robbins SJ, Hoffman JR (2006) Effects of Ginkgo biloba administered after spatial learning on water maze and radial arm maze performance in young adult rats. Pharmacol Biochem Behav 84(1):17-25
    • (2006) Pharmacol Biochem Behav , vol.84 , Issue.1 , pp. 17-25
    • Shif, O.1    Gillette, K.2    Damkaoutis, C.M.3    Carrano, C.4    Robbins, S.J.5    Hoffman, J.R.6
  • 52
    • 1542330244 scopus 로고    scopus 로고
    • Ginkgo biloba promotes short-term retention of spatial memory in rats
    • Hoffman JR, Donato A, Robbins SJ (2004) Ginkgo biloba promotes short-term retention of spatial memory in rats. Pharmacol Biochem Behav 77(3):533-539
    • (2004) Pharmacol Biochem Behav , vol.77 , Issue.3 , pp. 533-539
    • Hoffman, J.R.1    Donato, A.2    Robbins, S.J.3
  • 53
    • 33745015824 scopus 로고    scopus 로고
    • The in vivo synaptic plasticity mechanism of EGb 761-induced enhancement of spatial learning and memory in aged rats
    • Wang Y, Wang L, Wu J, Cai J (2006) The in vivo synaptic plasticity mechanism of EGb 761-induced enhancement of spatial learning and memory in aged rats. Br J Pharmacol 148(2):147-153
    • (2006) Br J Pharmacol , vol.148 , Issue.2 , pp. 147-153
    • Wang, Y.1    Wang, L.2    Wu, J.3    Cai, J.4
  • 54
    • 0030039729 scopus 로고    scopus 로고
    • Ginkgo biloba extract (EGb 761) independently improves changes in passive avoidance learning and brain membrane fluidity in the aging mouse
    • Stoll S, Scheuer K, Pohl O, Muller WE (1996) Ginkgo biloba extract (EGb 761) independently improves changes in passive avoidance learning and brain membrane fluidity in the aging mouse. Pharmacopsychiatry 29(4):144-149
    • (1996) Pharmacopsychiatry , vol.29 , Issue.4 , pp. 144-149
    • Stoll, S.1    Scheuer, K.2    Pohl, O.3    Muller, W.E.4
  • 55
    • 0036286950 scopus 로고    scopus 로고
    • Enhanced conditioned inhibitory avoidance by a combined extract of Zingiber officinale and Ginkgo biloba
    • Topic B, Hasenohrl RU, Hacker R, Huston JP (2002) Enhanced conditioned inhibitory avoidance by a combined extract of Zingiber officinale and Ginkgo biloba. Phytother Res 16(4):312-315
    • (2002) Phytother Res , vol.16 , Issue.4 , pp. 312-315
    • Topic, B.1    Hasenohrl, R.U.2    Hacker, R.3    Huston, J.P.4
  • 56
    • 0029928823 scopus 로고    scopus 로고
    • Ginkgo biloba extract protects brain neurons against oxidative stress induced by hydrogen peroxide
    • Oyama Y, Chikahisa L, Ueha T, Kanemaru K, Noda K (1996) Ginkgo biloba extract protects brain neurons against oxidative stress induced by hydrogen peroxide. Brain Res 712(2):349-352
    • (1996) Brain Res , vol.712 , Issue.2 , pp. 349-352
    • Oyama, Y.1    Chikahisa, L.2    Ueha, T.3    Kanemaru, K.4    Noda, K.5
  • 57
    • 0033109843 scopus 로고    scopus 로고
    • Gingko Biloba and memory for a maze
    • Gajewski A (1999) Gingko Biloba and memory for a maze. Psychol Rep 84:481-484
    • (1999) Psychol Rep , vol.84 , pp. 481-484
    • Gajewski, A.1
  • 58
    • 0026792734 scopus 로고
    • Effects of four non-cholinergic cognitive enhancers in comparison with tacrine and galanthamine on scopolamine-induced amnesia in rats
    • Chopin P, Briley M (1992) Effects of four non-cholinergic cognitive enhancers in comparison with tacrine and galanthamine on scopolamine-induced amnesia in rats. Psychopharmacology 106:26-30
    • (1992) Psychopharmacology , vol.106 , pp. 26-30
    • Chopin, P.1    Briley, M.2
  • 59
    • 0025604740 scopus 로고
    • Prevention by a Ginkgo Biloba extract (GBE 761) of the dopaminergic neurotoxicity of MPTP
    • Ramassamy C, Clostre F, Christen Y, Costentin J (1990) Prevention by a Ginkgo Biloba extract (GBE 761) of the dopaminergic neurotoxicity of MPTP. J Pharm Pharmacol 42:785-789
    • (1990) J Pharm Pharmacol , vol.42 , pp. 785-789
    • Ramassamy, C.1    Clostre, F.2    Christen, Y.3    Costentin, J.4
  • 61
    • 33747878212 scopus 로고    scopus 로고
    • Fruit and vegetable juices and Alzheimer’s disease: The Kame project
    • Dai Q, Borenstein AR, Wu Y, Jackson JC, Larson EB (2006) Fruit and vegetable juices and Alzheimer’s disease: the Kame project. Am J Med 119(9):751-759
    • (2006) Am J Med , vol.119 , Issue.9 , pp. 751-759
    • Dai, Q.1    Borenstein, A.R.2    Wu, Y.3    Jackson, J.C.4    Larson, E.B.5
  • 63
    • 34248190279 scopus 로고    scopus 로고
    • A beta oligomers-a decade of discovery
    • JNC4426 [pii]
    • Walsh DM, Selkoe DJ (2007) A beta oligomers-a decade of discovery. J Neurochem 101(5):1172-1184. doi:10.1111/j.1471-4159.2006.04426.x, JNC4426 [pii]
    • (2007) J Neurochem , vol.101 , Issue.5 , pp. 1172-1184
    • Walsh, D.M.1    Selkoe, D.J.2
  • 64
    • 44249116000 scopus 로고    scopus 로고
    • Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice
    • S0006-8993(08)00409-5 [pii]
    • Rezai-Zadeh K, Arendash GW, Hou H, Fernandez F, Jensen M, Runfeldt M, Shytle RD, Tan J (2008) Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice. Brain Res 1214:177-187. doi:10.1016/j.brainres.2008.02.107, S0006-8993(08)00409-5 [pii]
    • (2008) Brain Res , vol.1214 , pp. 177-187
    • Rezai-Zadeh, K.1    Arendash, G.W.2    Hou, H.3    Fernandez, F.4    Jensen, M.5    Runfeldt, M.6    Shytle, R.D.7    Tan, J.8
  • 65
    • 70149095473 scopus 로고    scopus 로고
    • Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Abeta1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus
    • S0306-4522(09)01133-6 [pii]
    • Li Q, Zhao HF, Zhang ZF, Liu ZG, Pei XR, Wang JB, Li Y (2009) Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Abeta1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus. Neuroscience 163(3):741-749. doi:10.1016/j.neuroscience.2009.07.014, S0306-4522(09)01133-6 [pii]
    • (2009) Neuroscience , vol.163 , Issue.3 , pp. 741-749
    • Li, Q.1    Zhao, H.F.2    Zhang, Z.F.3    Liu, Z.G.4    Pei, X.R.5    Wang, J.B.6    Li, Y.7
  • 66
    • 33745209915 scopus 로고    scopus 로고
    • ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein
    • M600617200 [pii]
    • Obregon DF, Rezai-Zadeh K, Bai Y, Sun N, Hou H, Ehrhart J, Zeng J, Mori T, Arendash GW, Shytle D, Town T, Tan J (2006) ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 281(24):16419-16427. doi:10.1074/jbc.M600617200, M600617200 [pii]
    • (2006) J Biol Chem , vol.281 , Issue.24 , pp. 16419-16427
    • Obregon, D.F.1    Rezai-Zadeh, K.2    Bai, Y.3    Sun, N.4    Hou, H.5    Ehrhart, J.6    Zeng, J.7    Mori, T.8    Arendash, G.W.9    Shytle, D.10    Town, T.11    Tan, J.12
  • 67
    • 77957128191 scopus 로고    scopus 로고
    • EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP
    • 0014-5793(10)00749-0 [pii]
    • Fernandez JW, Rezai-Zadeh K, Obregon D, Tan J (2010) EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP. FEBS Lett 584(19):4259-4267. doi:10.1016/j.febslet.2010.09.022, S0014-5793(10)00749-0 [pii]
    • (2010) FEBS Lett , vol.584 , Issue.19 , pp. 4259-4267
    • Fernandez, J.W.1    Rezai-Zadeh, K.2    Obregon, D.3    Tan, J.4
  • 68
    • 25444500410 scopus 로고    scopus 로고
    • Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice
    • 25/38/8807 [pii]
    • Rezai-Zadeh K, Shytle D, Sun N, Mori T, Hou H, Jeanniton D, Ehrhart J, Townsend K, Zeng J, Morgan D, Hardy J, Town T, Tan J (2005) Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. J Neurosci 25(38):8807-8814. doi:10.1523/JNEUROSCI.1521-05.2005, 25/38/8807 [pii]
    • (2005) J Neurosci , vol.25 , Issue.38 , pp. 8807-8814
    • Rezai-Zadeh, K.1    Shytle, D.2    Sun, N.3    Mori, T.4    Hou, H.5    Jeanniton, D.6    Ehrhart, J.7    Townsend, K.8    Zeng, J.9    Morgan, D.10    Hardy, J.11    Town, T.12    Tan, J.13
  • 69
    • 56049095730 scopus 로고    scopus 로고
    • Epigallocatechin gallate (EGCG) suppresses beta-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3 beta activation
    • S0197-4580(07)00213-8 [pii]
    • Lin CL, Chen TF, Chiu MJ, Way TD, Lin JK (2009) Epigallocatechin gallate (EGCG) suppresses beta-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3 beta activation. Neurobiol Aging 30(1):81-92. doi:10.1016/j.neurobiolaging.2007.05.012, S0197-4580(07)00213-8 [pii]
    • (2009) Neurobiol Aging , vol.30 , Issue.1 , pp. 81-92
    • Lin, C.L.1    Chen, T.F.2    Chiu, M.J.3    Way, T.D.4    Lin, J.K.5
  • 70
    • 54249143535 scopus 로고    scopus 로고
    • Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: Special reference to epigallocatechin gallate (EGCG)
    • Mandel SA, Amit T, Kalfon L, Reznichenko L, Weinreb O, Youdim MB (2008) Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate (EGCG). J Alzheimer’s Dis 15(2):211-222
    • (2008) J Alzheimer’s Dis , vol.15 , Issue.2 , pp. 211-222
    • Mandel, S.A.1    Amit, T.2    Kalfon, L.3    Reznichenko, L.4    Weinreb, O.5    Youdim, M.B.6
  • 71
    • 43249100611 scopus 로고    scopus 로고
    • Targeting multiple Alzheimer’s disease etiologies with multimodal neuroprotective and neurorestorative iron chelators
    • fj.07-8627rev [pii]
    • Amit T, Avramovich-Tirosh Y, Youdim MB, Mandel S (2008) Targeting multiple Alzheimer’s disease etiologies with multimodal neuroprotective and neurorestorative iron chelators. FASEB J 22(5):1296-1305. doi:10.1096/fj.07-8627rev, fj.07-8627rev [pii]
    • (2008) FASEB J , vol.22 , Issue.5 , pp. 1296-1305
    • Amit, T.1    Avramovich-Tirosh, Y.2    Youdim, M.B.3    Mandel, S.4
  • 72
    • 34249337528 scopus 로고    scopus 로고
    • Iron dysregulation in Alzheimer’s disease: Multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents
    • S0301-0082 (07)00105-0 [pii]
    • Mandel S, Amit T, Bar-Am O, Youdim MB (2007) Iron dysregulation in Alzheimer’s disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents. Prog Neurobiol 82(6):348-360. doi:10.1016/j.pneurobio.2007.06.001, S0301-0082 (07)00105-0 [pii]
    • (2007) Prog Neurobiol , vol.82 , Issue.6 , pp. 348-360
    • Mandel, S.1    Amit, T.2    Bar-Am, O.3    Youdim, M.B.4
  • 74
    • 77952346781 scopus 로고    scopus 로고
    • EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity
    • 0910723107 [pii]
    • Bieschke J, Russ J, Friedrich RP, Ehrnhoefer DE, Wobst H, Neugebauer K, Wanker EE (2010) EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity. Proc Natl Acad Sci USA 107(17):7710-7715. doi:10.1073/pnas.0910723107, 0910723107 [pii]
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.17 , pp. 7710-7715
    • Bieschke, J.1    Russ, J.2    Friedrich, R.P.3    Ehrnhoefer, D.E.4    Wobst, H.5    Neugebauer, K.6    Wanker, E.E.7
  • 75
    • 0141642253 scopus 로고    scopus 로고
    • Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: Implications for the prevention and therapeutics of Alzheimer’s disease
    • 1976 [pii]
    • Ono K, Yoshiike Y, Takashima A, Hasegawa K, Naiki H, Yamada M (2003) Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer’s disease. J Neurochem 87(1):172-181, 1976 [pii]
    • (2003) J Neurochem , vol.87 , Issue.1 , pp. 172-181
    • Ono, K.1    Yoshiike, Y.2    Takashima, A.3    Hasegawa, K.4    Naiki, H.5    Yamada, M.6
  • 76
    • 57749112087 scopus 로고    scopus 로고
    • Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity
    • M806154200 [pii]
    • Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, Teplow DB (2008) Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity. J Biol Chem 283(47):32176-32187. doi:10.1074/jbc.M806154200, M806154200 [pii]
    • (2008) J Biol Chem , vol.283 , Issue.47 , pp. 32176-32187
    • Ono, K.1    Condron, M.M.2    Ho, L.3    Wang, J.4    Zhao, W.5    Pasinetti, G.M.6    Teplow, D.B.7
  • 77
    • 33847025338 scopus 로고    scopus 로고
    • The anti-amyloidogenic effect is exerted against Alzheimer’s beta-amyloid fibrils in vitro by preferential and reversible binding of flavonoids to the amyloid fibril structure
    • Hirohata M, Hasegawa K, Tsutsumi-Yasuhara S, Ohhashi Y, Ookoshi T, Ono K, Yamada M, Naiki H (2007) The anti-amyloidogenic effect is exerted against Alzheimer’s beta-amyloid fibrils in vitro by preferential and reversible binding of flavonoids to the amyloid fibril structure. Biochemistry 46(7):1888-1899. doi:10.1021/bi061540x
    • (2007) Biochemistry , vol.46 , Issue.7 , pp. 1888-1899
    • Hirohata, M.1    Hasegawa, K.2    Tsutsumi-Yasuhara, S.3    Ohhashi, Y.4    Ookoshi, T.5    Ono, K.6    Yamada, M.7    Naiki, H.8
  • 78
    • 46749123053 scopus 로고    scopus 로고
    • Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer’s disease
    • 28/25/6388 [pii]
    • Wang J, Ho L, Zhao W, Ono K, Rosensweig C, Chen L, Humala N, Teplow DB, Pasinetti GM (2008) Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer’s disease. J Neurosci 28(25):6388-6392. doi:10.1523/JNEUROSCI.0364-08.2008, 28/25/6388 [pii]
    • (2008) J Neurosci , vol.28 , Issue.25 , pp. 6388-6392
    • Wang, J.1    Ho, L.2    Zhao, W.3    Ono, K.4    Rosensweig, C.5    Chen, L.6    Humala, N.7    Teplow, D.B.8    Pasinetti, G.M.9
  • 80
  • 81
    • 52649143244 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation
    • 00001756200808270-00017 [pii]
    • Shimmyo Y, Kihara T, Akaike A, Niidome T, Sugimoto H (2008) Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation. Neuroreport 19(13):1329-1333. doi:10.1097/WNR.0b013e32830b8ae1, 00001756200808270-00017 [pii]
    • (2008) Neuroreport , vol.19 , Issue.13 , pp. 1329-1333
    • Shimmyo, Y.1    Kihara, T.2    Akaike, A.3    Niidome, T.4    Sugimoto, H.5
  • 82
    • 45049086920 scopus 로고    scopus 로고
    • Flavonols and flavones as BACE-1 inhibitors: Structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features
    • S0304-4165(08)00029-9 [pii]
    • Shimmyo Y, Kihara T, Akaike A, Niidome T, Sugimoto H (2008) Flavonols and flavones as BACE-1 inhibitors: structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features. Biochim Biophys Acta 1780(5):819-825. doi:10.1016/j.bbagen.2008.01.017, S0304-4165(08)00029-9 [pii]
    • (2008) Biochim Biophys Acta , vol.1780 , Issue.5 , pp. 819-825
    • Shimmyo, Y.1    Kihara, T.2    Akaike, A.3    Niidome, T.4    Sugimoto, H.5
  • 83
    • 14844303721 scopus 로고    scopus 로고
    • Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins
    • M408714200 [pii]
    • Taniguchi S, Suzuki N, Masuda M, Hisanaga S, Iwatsubo T, Goedert M, Hasegawa M (2005) Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. J Biol Chem 280(9):7614-7623. doi:10.1074/jbc.M408714200, M408714200 [pii]
    • (2005) J Biol Chem , vol.280 , Issue.9 , pp. 7614-7623
    • Taniguchi, S.1    Suzuki, N.2    Masuda, M.3    Hisanaga, S.4    Iwatsubo, T.5    Goedert, M.6    Hasegawa, M.7
  • 84
    • 84861195616 scopus 로고    scopus 로고
    • Ultrastructural alterations of Alzheimer’s disease paired helical filaments by grape seed-derived polyphenols
    • S0197-4580(10) 00487-2 [pii]
    • Ksiezak-Reding H, Ho L, Santa-Maria I, Diaz-Ruiz C, Wang J, Pasinetti GM (2010) Ultrastructural alterations of Alzheimer’s disease paired helical filaments by grape seed-derived polyphenols. Neurobiol Aging. doi:10.1016/j.neurobiolaging.2010.11.006, S0197-4580(10) 00487-2 [pii]
    • (2010) Neurobiol Aging
    • Ksiezak-Reding, H.1    Ho, L.2    Santa-Maria, I.3    Diaz-Ruiz, C.4    Wang, J.5    Pasinetti, G.M.6
  • 85
    • 78650816787 scopus 로고    scopus 로고
    • Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer’s disease
    • 6116T35519044794 [pii]
    • Wang J, Santa-Maria I, Ho L, Ksiezak-Reding H, Ono K, Teplow DB, Pasinetti GM (2010) Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer’s disease. J Alzheimer’s Dis 22(2):653-661. doi:10.3233/JAD-2010-101074, 6116T35519044794 [pii]
    • (2010) J Alzheimer’s Dis , vol.22 , Issue.2 , pp. 653-661
    • Wang, J.1    Santa-Maria, I.2    Ho, L.3    Ksiezak-Reding, H.4    Ono, K.5    Teplow, D.B.6    Pasinetti, G.M.7
  • 86
    • 77956314492 scopus 로고    scopus 로고
    • Development of a grape seed polyphenolic extract with anti-oligomeric activity as a novel treatment in progressive supranuclear palsy and other tauopathies
    • JNC6875 [pii]
    • Pasinetti GM, Ksiezak-Reding H, Santa-Maria I, Wang J, Ho L (2010) Development of a grape seed polyphenolic extract with anti-oligomeric activity as a novel treatment in progressive supranuclear palsy and other tauopathies. J Neurochem 114(6):1557-1568. doi:10.1111/j.1471-4159.2010.06875.x, JNC6875 [pii]
    • (2010) J Neurochem , vol.114 , Issue.6 , pp. 1557-1568
    • Pasinetti, G.M.1    Ksiezak-Reding, H.2    Santa-Maria, I.3    Wang, J.4    Ho, L.5
  • 87
    • 60349096854 scopus 로고    scopus 로고
    • Grape seed polyphenolic extract as a potential novel therapeutic agent in tauopathies
    • FQ65P9545646548M [pii]
    • Ho L, Yemul S, Wang J, Pasinetti GM (2009) Grape seed polyphenolic extract as a potential novel therapeutic agent in tauopathies. J Alzheimers Dis 16(2):433-439. doi:10.3233/JAD-2009-0969, FQ65P9545646548M [pii]
    • (2009) J Alzheimers Dis , vol.16 , Issue.2 , pp. 433-439
    • Ho, L.1    Yemul, S.2    Wang, J.3    Pasinetti, G.M.4
  • 88
    • 34249788691 scopus 로고    scopus 로고
    • (-)-epicatechin stimulates ERK-dependent cyclic AMP response element activity and upregulates GLUR2 in cortical neurons
    • Schroeter H, Bahia P, Spencer JPE, Sheppard O, Rattray M, Rice-Evans C, Williams RJ (2007) (-)-epicatechin stimulates ERK-dependent cyclic AMP response element activity and upregulates GLUR2 in cortical neurons. J Neurochem 101:1596-1606
    • (2007) J Neurochem , vol.101 , pp. 1596-1606
    • Schroeter, H.1    Bahia, P.2    Spencer, J.3    Sheppard, O.4    Rattray, M.5    Rice-Evans, C.6    Williams, R.J.7
  • 89
    • 35448949428 scopus 로고    scopus 로고
    • Activation of prosurvival Akt and ERK1/2 signaling pathways underlie the anti-apoptotic effects of flava-nones in cortical neurons
    • Vauzour D, VafeiAdou K, Rice-Evans C, Williams RJ, Spencer JP (2007) Activation of prosurvival Akt and ERK1/2 signaling pathways underlie the anti-apoptotic effects of flava-nones in cortical neurons. J Neurochem 103(4):1355-1367
    • (2007) J Neurochem , vol.103 , Issue.4 , pp. 1355-1367
    • Vauzour, D.1    Vafeiadou, K.2    Rice-Evans, C.3    Williams, R.J.4    Spencer, J.P.5
  • 90
    • 3042667647 scopus 로고    scopus 로고
    • Catechin polyphenols: Neurodegeneration and neuroprotection in neurodegenerative diseases
    • Mandel S, Youdim MB (2004) Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases. Free Radic Biol Med 37(3):304-317
    • (2004) Free Radic Biol Med , vol.37 , Issue.3 , pp. 304-317
    • Mandel, S.1    Youdim, M.B.2
  • 91
    • 0037090246 scopus 로고    scopus 로고
    • Parkinson’s disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake
    • Checkoway H, Powers K, Smith-Weller T, Franklin GM, Longstreth WT Jr, Swanson PD (2002) Parkinson’s disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake. Am J Epidemiol 155(8):732-738
    • (2002) Am J Epidemiol , vol.155 , Issue.8 , pp. 732-738
    • Checkoway, H.1    Powers, K.2    Smith-Weller, T.3    Franklin, G.M.4    Longstreth, W.T.5    Swanson, P.D.6
  • 92
    • 4444226105 scopus 로고    scopus 로고
    • Neurological mechanisms of green tea polyphenols in Alzheimer’s and Parkinson’s diseases
    • S0955286304001184 [pii]
    • Weinreb O, Mandel S, Amit T, Youdim MB (2004) Neurological mechanisms of green tea polyphenols in Alzheimer’s and Parkinson’s diseases. J Nutr Biochem 15(9):506-516. doi:10.1016/j.jnutbio.2004.05.002, S0955286304001184 [pii]
    • (2004) J Nutr Biochem , vol.15 , Issue.9 , pp. 506-516
    • Weinreb, O.1    Mandel, S.2    Amit, T.3    Youdim, M.B.4
  • 93
    • 79960722781 scopus 로고    scopus 로고
    • Understanding the broad-spectrum neuroprotective action profile of green tea polyphenols in aging and neurodegenerative diseases
    • T78514153PM2L2R3 [pii]
    • Mandel SA, Amit T, Weinreb O, Youdim MB (2011) Understanding the broad-spectrum neuroprotective action profile of green tea polyphenols in aging and neurodegenerative diseases. J Alzheimer’s Dis. doi:10.3233/JAD-2011-101803, T78514153PM2L2R3 [pii]
    • (2011) J Alzheimer’s Dis
    • Mandel, S.A.1    Amit, T.2    Weinreb, O.3    Youdim, M.B.4
  • 94
    • 0036145435 scopus 로고    scopus 로고
    • Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures
    • Levites Y, Youdim MB, Maor G, Mandel S (2002) Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures. Biochem Pharmacol 63(1):21-29
    • (2002) Biochem Pharmacol , vol.63 , Issue.1 , pp. 21-29
    • Levites, Y.1    Youdim, M.B.2    Maor, G.3    Mandel, S.4
  • 95
    • 0034851553 scopus 로고    scopus 로고
    • Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration
    • Levites Y, Weinreb O, Maor G, Youdim MB, Mandel S (2001) Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration. J Neurochem 78(5):1073-1082
    • (2001) J Neurochem , vol.78 , Issue.5 , pp. 1073-1082
    • Levites, Y.1    Weinreb, O.2    Maor, G.3    Youdim, M.B.4    Mandel, S.5
  • 96
    • 0036074531 scopus 로고    scopus 로고
    • 5-s-Cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons
    • Spencer JPE, Whiteman M, Jenner P, Halliwell B (2002) 5-s-Cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons. J Neurochem 81(1):122-129
    • (2002) J Neurochem , vol.81 , Issue.1 , pp. 122-129
    • Spencer, J.1    Whiteman, M.2    Jenner, P.3    Halliwell, B.4
  • 97
    • 48049106637 scopus 로고    scopus 로고
    • Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: Implications for Parkinson’s disease and protection by polyphenols
    • Vauzour D, Ravaioli G, VafeiAdou K, Rodriguez-Mateos A, Angeloni C, Spencer JP (2008) Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson’s disease and protection by polyphenols. Arch Biochem Biophys 476(2):145-151
    • (2008) Arch Biochem Biophys , vol.476 , Issue.2 , pp. 145-151
    • Vauzour, D.1    Ravaioli, G.2    Vafeiadou, K.3    Rodriguez-Mateos, A.4    Angeloni, C.5    Spencer, J.P.6
  • 98
    • 0034733810 scopus 로고    scopus 로고
    • Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils
    • Lee S, Suh S, Kim S (2000) Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils. Neurosci Lett 287(3):191-194
    • (2000) Neurosci Lett , vol.287 , Issue.3 , pp. 191-194
    • Lee, S.1    Suh, S.2    Kim, S.3
  • 99
    • 78650525484 scopus 로고    scopus 로고
    • ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington’s disease
    • ddq460 [pii]
    • Maher P, Dargusch R, Bodai L, Gerard PE, Purcell JM, Marsh JL (2011) ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington’s disease. Hum Mol Genet 20(2):261-270. doi:10.1093/hmg/ddq460, ddq460 [pii]
    • (2011) Hum Mol Genet , vol.20 , Issue.2 , pp. 261-270
    • Maher, P.1    Dargusch, R.2    Bodai, L.3    Gerard, P.E.4    Purcell, J.M.5    Marsh, J.L.6
  • 100
    • 71949125029 scopus 로고    scopus 로고
    • Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin
    • Maher P (2009) Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin. Genes Nutr. doi:10.1007/s12263-009-0142-5
    • (2009) Genes Nutr.
    • Maher, P.1
  • 101
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • S0092-8674(10)00168-6 [pii]
    • Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140(6):918-934. doi:10.1016/j.cell.2010.02.016, S0092-8674(10)00168-6 [pii]
    • (2010) Cell , vol.140 , Issue.6 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 102
    • 0042632879 scopus 로고    scopus 로고
    • Inflammatory processes in Alzheimer’s disease
    • S0278-5846(03)00124-6 [pii]
    • McGeer EG, McGeer PL (2003) Inflammatory processes in Alzheimer’s disease. Prog Neuropsychopharmacol Biol Psychiatry 27(5):741-749. doi:10.1016/S0278-5846(03) 00124-6, S0278-5846(03)00124-6 [pii]
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , Issue.5 , pp. 741-749
    • Mc Geer, E.G.1    Mc Geer, P.L.2
  • 103
    • 77956958953 scopus 로고    scopus 로고
    • Neuroinflammation is a key player in Parkinson’s disease and a prime target for therapy
    • Qian L, Flood PM, Hong JS (2010) Neuroinflammation is a key player in Parkinson’s disease and a prime target for therapy. J Neural Transm 117(8):971-979. doi:10.1007/s00702-010-0428-1
    • (2010) J Neural Transm , vol.117 , Issue.8 , pp. 971-979
    • Qian, L.1    Flood, P.M.2    Hong, J.S.3
  • 104
    • 78549247765 scopus 로고    scopus 로고
    • The dual role of the neuroinflammatory response after ischemic stroke: Modulatory effects of hypothermia
    • 17422094-7-74 [pii]
    • Ceulemans AG, Zgavc T, Kooijman R, Hachimi-Idrissi S, Sarre S, Michotte Y (2010) The dual role of the neuroinflammatory response after ischemic stroke: modulatory effects of hypothermia. J Neuroinflammation 7:74. doi:10.1186/1742-2094-7-74, 17422094-7-74 [pii]
    • (2010) J Neuroinflammation , vol.7 , pp. 74
    • Ceulemans, A.G.1    Zgavc, T.2    Kooijman, R.3    Hachimi-Idrissi, S.4    Sarre, S.5    Michotte, Y.6
  • 106
    • 77955085839 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration and mechanisms of microglial killing of neurons
    • Brown GC, Neher JJ (2010) Inflammatory neurodegeneration and mechanisms of microglial killing of neurons. Mol Neurobiol 41(2-3):242-247. doi:10.1007/s12035-010-8105-9
    • (2010) Mol Neurobiol , vol.41 , Issue.2-3 , pp. 242-247
    • Brown, G.C.1    Neher, J.J.2
  • 107
    • 79551591722 scopus 로고    scopus 로고
    • Astrocyte-neuron metabolic relationships: For better and for worse
    • S0166-2236(10)00169-4 [pii]
    • Allaman I, Belanger M, Magistretti PJ (2011) Astrocyte-neuron metabolic relationships: for better and for worse. Trends Neurosci 34(2):76-87. doi:10.1016/j.tins.2010.12.001, S0166-2236(10)00169-4 [pii]
    • (2011) Trends Neurosci , vol.34 , Issue.2 , pp. 76-87
    • Allaman, I.1    Belanger, M.2    Magistretti, P.J.3
  • 108
    • 33644891895 scopus 로고    scopus 로고
    • Diagnosis and treatment of multiple sclerosis
    • 332/7540/525 [pii]
    • Murray TJ (2006) Diagnosis and treatment of multiple sclerosis. BMJ 332(7540):525-527. doi:10.1136/bmj.332.7540.525, 332/7540/525 [pii]
    • (2006) BMJ , vol.332 , Issue.7540 , pp. 525-527
    • Murray, T.J.1
  • 110
    • 0024339989 scopus 로고
    • Risk factors in multiple sclerosis: A population-based case-control study in Hautes-Pyrenees, France
    • Berr C, Puel J, Clanet M, Ruidavets JB, Mas JL, Alperovitch A (1989) Risk factors in multiple sclerosis: a population-based case-control study in Hautes-Pyrenees, France. Acta Neurol Scand 80(1):46-50
    • (1989) Acta Neurol Scand , vol.80 , Issue.1 , pp. 46-50
    • Berr, C.1    Puel, J.2    Clanet, M.3    Ruidavets, J.B.4    Mas, J.L.5    Alperovitch, A.6
  • 111
    • 0035838314 scopus 로고    scopus 로고
    • Intakes of carotenoids, vitamin C, and vitamin E and MS risk among two large cohorts of women
    • Zhang SM, Hernan MA, Olek MJ, Spiegelman D, Willett WC, Ascherio A (2001) Intakes of carotenoids, vitamin C, and vitamin E and MS risk among two large cohorts of women. Neurology 57(1):75-80
    • (2001) Neurology , vol.57 , Issue.1 , pp. 75-80
    • Zhang, S.M.1    Hernan, M.A.2    Olek, M.J.3    Spiegelman, D.4    Willett, W.C.5    Ascherio, A.6
  • 112
    • 34447508481 scopus 로고    scopus 로고
    • Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors
    • Ascherio A, Munger KL (2007) Environmental risk factors for multiple sclerosis. Part II: noninfectious factors. Ann Neurol 61(6):504-513. doi:10.1002/ana.21141
    • (2007) Ann Neurol , vol.61 , Issue.6 , pp. 504-513
    • Ascherio, A.1    Munger, K.L.2
  • 113
    • 6344274849 scopus 로고    scopus 로고
    • Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis
    • 173/9/5794 [pii]
    • Aktas O, Prozorovski T, Smorodchenko A, Savaskan NE, Lauster R, Kloetzel PM, Infante-Duarte C, Brocke S, Zipp F (2004) Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis. J Immunol 173(9):5794-5800, 173/9/5794 [pii]
    • (2004) J Immunol , vol.173 , Issue.9 , pp. 5794-5800
    • Aktas, O.1    Prozorovski, T.2    Smorodchenko, A.3    Savaskan, N.E.4    Lauster, R.5    Kloetzel, P.M.6    Infante-Duarte, C.7    Brocke, S.8    Zipp, F.9
  • 114
    • 4544312491 scopus 로고    scopus 로고
    • Quercetin, a flavonoid phytoestrogen, ameliorates experimental allergic encephalomyelitis by blocking IL-12 signaling through JAK-STAT pathway in T lymphocyte
    • 491536 [pii]
    • Muthian G, Bright JJ (2004) Quercetin, a flavonoid phytoestrogen, ameliorates experimental allergic encephalomyelitis by blocking IL-12 signaling through JAK-STAT pathway in T lymphocyte. J Clin Immunol 24(5):542-552. doi:10.1023/B:J0CI.0000040925.55682.a5, 491536 [pii]
    • (2004) J Clin Immunol , vol.24 , Issue.5 , pp. 542-552
    • Muthian, G.1    Bright, J.J.2
  • 116
    • 11844264954 scopus 로고    scopus 로고
    • Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis
    • jem.20040819 [pii]
    • Hendriks JJ, Alblas J, van der Pol SM, van Tol EA, Dijkstra CD, de Vries HE (2004) Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis. J Exp Med 200(12):1667-1672. doi:10.1084/jem.20040819, jem.20040819 [pii]
    • (2004) J Exp Med , vol.200 , Issue.12 , pp. 1667-1672
    • Hendriks, J.J.1    Alblas, J.2    Van Der Pol, S.M.3    Van Tol, E.A.4    Dijkstra, C.D.5    De Vries, H.E.6
  • 117
    • 3242720446 scopus 로고    scopus 로고
    • The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells
    • S000629520400320X [pii]
    • Verbeek R, Plomp AC, van Tol EA, van Noort JM (2004) The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells. Biochem Pharmacol 68(4):621-629. doi:10.1016/j.bcp. 2004.05.012, S000629520400320X [pii]
    • (2004) Biochem Pharmacol , vol.68 , Issue.4 , pp. 621-629
    • Verbeek, R.1    Plomp, A.C.2    Van Tol, E.A.3    Van Noort, J.M.4
  • 118
    • 0037141773 scopus 로고    scopus 로고
    • In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production
    • S0014299902017922 [pii]
    • Shen SC, Lee WR, Lin HY, Huang HC, Ko CH, Yang LL, Chen YC (2002) In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production. Eur J Pharmacol 446(1-3):187-194, S0014299902017922 [pii]
    • (2002) Eur J Pharmacol , vol.446 , Issue.1-3 , pp. 187-194
    • Shen, S.C.1    Lee, W.R.2    Lin, H.Y.3    Huang, H.C.4    Ko, C.H.5    Yang, L.L.6    Chen, Y.C.7
  • 119
    • 33646542712 scopus 로고    scopus 로고
    • Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity
    • S0171-2985(06)00024-6 [pii]
    • Woo KJ, Lim JH, Suh SI, Kwon YK, Shin SW, Kim SC, Choi YH, Park JW, Kwon TK (2006) Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity. Immunobiology 211(5):359-368. doi:10.1016/j.imbio.2006.02.002, S0171-2985(06)00024-6 [pii]
    • (2006) Immunobiology , vol.211 , Issue.5 , pp. 359-368
    • Woo, K.J.1    Lim, J.H.2    Suh, S.I.3    Kwon, Y.K.4    Shin, S.W.5    Kim, S.C.6    Choi, Y.H.7    Park, J.W.8    Kwon, T.K.9
  • 120
    • 77049088494 scopus 로고    scopus 로고
    • S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 Co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alpha
    • S0197-4580(08)00167-X [pii]
    • Bianchi R, Giambanco I, Donato R (2010) S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 Co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alpha. Neurobiol Aging 31(4):665-677. doi:10.1016/j.neurobiolaging.2008.05.017, S0197-4580(08)00167-X [pii]
    • (2010) Neurobiol Aging , vol.31 , Issue.4 , pp. 665-677
    • Bianchi, R.1    Giambanco, I.2    Donato, R.3
  • 121
    • 78149294702 scopus 로고    scopus 로고
    • Reactive oxygen species-dependent c-Fos/activator protein 1 induction upregulates heme oxygenase-1 expression by bradykinin in brain astrocytes
    • Hsieh HL, Wang HH, Wu CY, Yang CM (2010) Reactive oxygen species-dependent c-Fos/activator protein 1 induction upregulates heme oxygenase-1 expression by bradykinin in brain astrocytes. Antioxid Redox Signal 13(12):1829-1844. doi:10.1089/ars.2009.2957
    • (2010) Antioxid Redox Signal , vol.13 , Issue.12 , pp. 1829-1844
    • Hsieh, H.L.1    Wang, H.H.2    Wu, C.Y.3    Yang, C.M.4
  • 122
    • 44949125522 scopus 로고    scopus 로고
    • Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1
    • 0802865105 [pii]
    • Jang S, Kelley KW, Johnson RW (2008) Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1. Proc Natl Acad Sci USA 105(21):7534-7539. doi:10.1073/pnas.0802865105, 0802865105 [pii]
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.21 , pp. 7534-7539
    • Jang, S.1    Kelley, K.W.2    Johnson, R.W.3
  • 123
    • 78149278990 scopus 로고    scopus 로고
    • Astrocytes in injury states rapidly produce anti-inflammatory factors and attenuate microglial inflammatory responses
    • Kim JH, Min KJ, Seol W, Jou I, Joe EH (2010) Astrocytes in injury states rapidly produce anti-inflammatory factors and attenuate microglial inflammatory responses. J Neurochem 115(5):1161-1171. doi:10.1111/j.1471-4159.2010.07004.x
    • (2010) J Neurochem , vol.115 , Issue.5 , pp. 1161-1171
    • Kim, J.H.1    Min, K.J.2    Seol, W.3    Jou, I.4    Joe, E.H.5
  • 124
    • 0034604542 scopus 로고    scopus 로고
    • Involvement of STAT-1 and ets family members in interferon-gamma induction of CD40 transcription in microglia/macrophages
    • M002482200 [pii]
    • Nguyen VT, Benveniste EN (2000) Involvement of STAT-1 and ets family members in interferon-gamma induction of CD40 transcription in microglia/macrophages. J Biol Chem 275(31):23674-23684. doi:10.1074/jbc.M002482200, M002482200 [pii]
    • (2000) J Biol Chem , vol.275 , Issue.31 , pp. 23674-23684
    • Nguyen, V.T.1    Benveniste, E.N.2
  • 125
    • 77952411101 scopus 로고    scopus 로고
    • Inhibition of IkappaB kinasebeta protects dopamine neurons against lipopolysaccharide-induced neurotoxicity
    • jpet.110.165829 [pii]
    • Zhang F, Qian L, Flood PM, Shi JS, Hong JS, Gao HM (2010) Inhibition of IkappaB kinasebeta protects dopamine neurons against lipopolysaccharide-induced neurotoxicity. J Pharmacol Exp Ther 333(3):822-833. doi:10.1124/jpet.110.165829, jpet.110.165829 [pii]
    • (2010) J Pharmacol Exp Ther , vol.333 , Issue.3 , pp. 822-833
    • Zhang, F.1    Qian, L.2    Flood, P.M.3    Shi, J.S.4    Hong, J.S.5    Gao, H.M.6
  • 126
    • 33645541093 scopus 로고    scopus 로고
    • The flavonoid quercetin inhibits proinflammatory cytokine (Tumor necrosis factor alpha) gene expression in normal peripheral blood mononuclear cells via modulation of the NF-kappa beta system
    • 13/3/319 [pii]
    • Nair MP, Mahajan S, Reynolds JL, Aalinkeel R, Nair H, Schwartz SA, Kandaswami C (2006) The flavonoid quercetin inhibits proinflammatory cytokine (tumor necrosis factor alpha) gene expression in normal peripheral blood mononuclear cells via modulation of the NF-kappa beta system. Clin Vaccine Immunol 13(3):319-328. doi:10.1128/CVI.13.3.319-328.2006, 13/3/319 [pii]
    • (2006) Clin Vaccine Immunol , vol.13 , Issue.3 , pp. 319-328
    • Nair, M.P.1    Mahajan, S.2    Reynolds, J.L.3    Aalinkeel, R.4    Nair, H.5    Schwartz, S.A.6    Kandaswami, C.7
  • 127
    • 26444594915 scopus 로고    scopus 로고
    • Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia
    • S0014-2999(05)00788-0 [pii]
    • Chen JC, Ho FM, Pei-Dawn Lee C, Chen CP, Jeng KC, Hsu HB, Lee ST, Wen Tung W, Lin WW (2005) Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia. Eur J Pharmacol 521(1-3):9-20. doi:10.1016/j.ejphar.2005.08.005, S0014-2999(05)00788-0 [pii]
    • (2005) Eur J Pharmacol , vol.521 , Issue.1-3 , pp. 9-20
    • Chen, J.C.1    Ho, F.M.2    Pei-Dawn Lee, C.3    Chen, C.P.4    Jeng, K.C.5    Hsu, H.B.6    Lee, S.T.7    Wen Tung, W.8    Lin, W.W.9
  • 128
    • 0034213030 scopus 로고    scopus 로고
    • Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation
    • S0006295200002550 [pii]
    • Chen Y, Yang L, Lee TJ (2000) Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation. Biochem Pharmacol 59(11):1445-1457, S0006295200002550 [pii]
    • (2000) Biochem Pharmacol , vol.59 , Issue.11 , pp. 1445-1457
    • Chen, Y.1    Yang, L.2    Lee, T.J.3
  • 129
    • 0032831286 scopus 로고    scopus 로고
    • Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages
    • Liang YC, Huang YT, Tsai SH, Lin-Shiau SY, Chen CF, Lin JK (1999) Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages. Carcinogenesis 20(10):1945-1952
    • (1999) Carcinogenesis , vol.20 , Issue.10 , pp. 1945-1952
    • Liang, Y.C.1    Huang, Y.T.2    Tsai, S.H.3    Lin-Shiau, S.Y.4    Chen, C.F.5    Lin, J.K.6
  • 130
    • 0030799810 scopus 로고    scopus 로고
    • (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB
    • Lin YL, Lin JK (1997) (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol Pharmacol 52(3):465-472
    • (1997) Mol Pharmacol , vol.52 , Issue.3 , pp. 465-472
    • Lin, Y.L.1    Lin, J.K.2
  • 131
    • 20444387289 scopus 로고    scopus 로고
    • (+)-Catechin, an ingredient of green tea, protects murine microglia from oxidative stress-induced DNA damage and cell cycle arrest
    • JST.JSTAGE/jphs/FPJ04053X [pii]
    • Huang Q, Wu LJ, Tashiro S, Gao HY, Onodera S, Ikejima T (2005) (+)-Catechin, an ingredient of green tea, protects murine microglia from oxidative stress-induced DNA damage and cell cycle arrest. J Pharmacol Sci 98(1):16-24, JST.JSTAGE/jphs/FPJ04053X [pii]
    • (2005) J Pharmacol Sci , vol.98 , Issue.1 , pp. 16-24
    • Huang, Q.1    Wu, L.J.2    Tashiro, S.3    Gao, H.Y.4    Onodera, S.5    Ikejima, T.6
  • 132
    • 0042762838 scopus 로고    scopus 로고
    • Luteolin inhibits the nuclear factor-kappa B transcriptional activity in Rat-1 fibroblasts
    • S0006295203004659 [pii]
    • Kim SH, Shin KJ, Kim D, Kim YH, Han MS, Lee TG, Kim E, Ryu SH, Suh PG (2003) Luteolin inhibits the nuclear factor-kappa B transcriptional activity in Rat-1 fibroblasts. Biochem Pharmacol 66(6):955-963, S0006295203004659 [pii]
    • (2003) Biochem Pharmacol , vol.66 , Issue.6 , pp. 955-963
    • Kim, S.H.1    Shin, K.J.2    Kim, D.3    Kim, Y.H.4    Han, M.S.5    Lee, T.G.6    Kim, E.7    Ryu, S.H.8    Suh, P.G.9
  • 133
    • 0035903037 scopus 로고    scopus 로고
    • The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production
    • S0304-3940(01)02028-6 [pii]
    • Kim H, Kim YS, Kim SY, Suk K (2001) The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production. Neurosci Lett 309(1):67-71, S0304-3940(01)02028-6 [pii]
    • (2001) Neurosci Lett , vol.309 , Issue.1 , pp. 67-71
    • Kim, H.1    Kim, Y.S.2    Kim, S.Y.3    Suk, K.4
  • 134
  • 135
    • 0037404413 scopus 로고    scopus 로고
    • Flavonoid baicalein attenuates activation-induced cell death of brain microglia
    • Suk K, Lee H, Kang SS, Cho GJ, Choi WS (2003) Flavonoid baicalein attenuates activation-induced cell death of brain microglia. J Pharmacol Exp Ther 305(2):638-645. doi:10.1124/jpet.102.047373 [pii]
    • (2003) J Pharmacol Exp Ther , vol.305 , Issue.2 , pp. 638-645
    • Suk, K.1    Lee, H.2    Kang, S.S.3    Cho, G.J.4    Choi, W.S.5
  • 136
    • 58749101482 scopus 로고    scopus 로고
    • Inhibition of hemolysate-induced iNOS and COX-2 expression by genistein through suppression of NF-small ka, CyrillicB activation in primary astrocytes
    • S0022-510X(08)00599-6 [pii]
    • Lu H, Shi JX, Zhang DM, Wang HD, Hang CH, Chen HL, Yin HX (2009) Inhibition of hemolysate-induced iNOS and COX-2 expression by genistein through suppression of NF-small ka, CyrillicB activation in primary astrocytes. J Neurol Sci 278(1-2):91-95. doi:10.1016/j.jns.2008.12.007, S0022-510X(08)00599-6 [pii]
    • (2009) J Neurol Sci , vol.278 , Issue.1-2 , pp. 91-95
    • Lu, H.1    Shi, J.X.2    Zhang, D.M.3    Wang, H.D.4    Hang, C.H.5    Chen, H.L.6    Yin, H.X.7
  • 137
    • 49549112269 scopus 로고    scopus 로고
    • Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes
    • JNC5542 [pii]
    • Bahia PK, Rattray M, Williams RJ (2008) Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes. J Neurochem 106(5):2194-2204. doi:10.1111/j.1471-4159.2008.05542.x, JNC5542 [pii]
    • (2008) J Neurochem , vol.106 , Issue.5 , pp. 2194-2204
    • Bahia, P.K.1    Rattray, M.2    Williams, R.J.3
  • 138
    • 63049125250 scopus 로고    scopus 로고
    • The impact of flavonoids on memory: Physiological and molecular considerations
    • Spencer JP (2009) The impact of flavonoids on memory: physiological and molecular considerations. Chem Soc Rev 38(4):1152-1161. doi:10.1039/b800422f
    • (2009) Chem Soc Rev , vol.38 , Issue.4 , pp. 1152-1161
    • Spencer, J.P.1
  • 139
    • 0036436191 scopus 로고    scopus 로고
    • Neurogenesis may relate to some but not all types of hippocampal-dependent learning
    • Shors TJ, Townsend DA, Zhao M, Kozorovitskiy Y, Gould E (2002) Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus 12(5):578-584. doi:10.1002/hipo.10103
    • (2002) Hippocampus , vol.12 , Issue.5 , pp. 578-584
    • Shors, T.J.1    Townsend, D.A.2    Zhao, M.3    Kozorovitskiy, Y.4    Gould, E.5
  • 140
    • 0030842112 scopus 로고    scopus 로고
    • Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition
    • S0006-2952(97)82453-7 [pii]
    • Agullo G, Gamet-Payrastre L, Manenti S, Viala C, Remesy C, Chap H, Payrastre B (1997) Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition. Biochem Pharmacol 53(11):1649-1657, S0006-2952(97)82453-7 [pii]
    • (1997) Biochem Pharmacol , vol.53 , Issue.11 , pp. 1649-1657
    • Agullo, G.1    Gamet-Payrastre, L.2    Manenti, S.3    Viala, C.4    Remesy, C.5    Chap, H.6    Payrastre, B.7
  • 141
    • 20044396748 scopus 로고    scopus 로고
    • GABA(A) receptor channel pharmacology
    • Johnston GA (2005) GABA(A) receptor channel pharmacology. Curr Pharm Des 11(15):1867-1885
    • (2005) Curr Pharm Des , vol.11 , Issue.15 , pp. 1867-1885
    • Johnston, G.A.1
  • 142
    • 0033634827 scopus 로고    scopus 로고
    • Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine
    • S1097-2765(05)00089-4 [pii]
    • Walker EH, Pacold ME, Perisic O, Stephens L, Hawkins PT, Wymann MP, Williams RL (2000) Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol Cell 6(4):909-919, S1097-2765(05)00089-4 [pii]
    • (2000) Mol Cell , vol.6 , Issue.4 , pp. 909-919
    • Walker, E.H.1    Pacold, M.E.2    Perisic, O.3    Stephens, L.4    Hawkins, P.T.5    Wymann, M.P.6    Williams, R.L.7
  • 143
    • 0035989543 scopus 로고    scopus 로고
    • Interactions of flavones and other phytochemicals with adenosine receptors
    • Jacobson KA, Moro S, Manthey JA, West PL, Ji XD (2002) Interactions of flavones and other phytochemicals with adenosine receptors. Adv Exp Med Biol 505:163-171
    • (2002) Adv Exp Med Biol , vol.505 , pp. 163-171
    • Jacobson, K.A.1    Moro, S.2    Manthey, J.A.3    West, P.L.4    Ji, X.D.5
  • 144
    • 32044438645 scopus 로고    scopus 로고
    • (-)-Epigallocatechin gallate attenuates acute stress responses through GABAergic system in the brain
    • S0014-2999(05)01326-9 [pii]
    • Adachi N, Tomonaga S, Tachibana T, Denbow DM, Furuse M (2006) (-)-Epigallocatechin gallate attenuates acute stress responses through GABAergic system in the brain. Eur J Pharmacol 531(1-3):171-175. doi:10.1016/j.ejphar.2005.12.024, S0014-2999(05)01326-9 [pii]
    • (2006) Eur J Pharmacol , vol.531 , Issue.1-3 , pp. 171-175
    • Adachi, N.1    Tomonaga, S.2    Tachibana, T.3    Denbow, D.M.4    Furuse, M.5
  • 145
    • 38349008651 scopus 로고    scopus 로고
    • The interactions of flavonoids within neuronal signalling pathways
    • Spencer JP (2007) The interactions of flavonoids within neuronal signalling pathways. Genes Nutr 2(3):257-273. doi:10.1007/s12263-007-0056-z
    • (2007) Genes Nutr , vol.2 , Issue.3 , pp. 257-273
    • Spencer, J.P.1
  • 147
    • 0037116579 scopus 로고    scopus 로고
    • Apigenin and LY294002 prolong EGF-stimulated ERK1/2 activation in PC12 cells but are unable to induce full differentiation
    • S0014579301032525 [pii]
    • Llorens F, Garcia L, Itarte E, Gomez N (2002) Apigenin and LY294002 prolong EGF-stimulated ERK1/2 activation in PC12 cells but are unable to induce full differentiation. FEBS Lett 510(3):149-153, S0014579301032525 [pii]
    • (2002) FEBS Lett 510(3) , pp. 149-153
    • Llorens, F.1    Garcia, L.2    Itarte, E.3    Gomez, N.4
  • 148
    • 0032195577 scopus 로고    scopus 로고
    • Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning
    • Impey S, Smith DM, Obrietan K, Donahue R, Wade C, Storm DR (1998) Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning. Nat Neurosci 1(7):595-601. doi:10.1038/2830
    • (1998) Nat Neurosci , vol.1 , Issue.7 , pp. 595-601
    • Impey, S.1    Smith, D.M.2    Obrietan, K.3    Donahue, R.4    Wade, C.5    Storm, D.R.6
  • 149
    • 0028071507 scopus 로고
    • Deficient longterm memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
    • 0092-8674(94)90400-6 [pii]
    • Bourtchuladze R, Frenguelli B, Blendy J, Cioffi D, Schutz G, Silva AJ (1994) Deficient longterm memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell 79(1):59-68, 0092-8674(94)90400-6 [pii]
    • (1994) Cell , vol.79 , Issue.1 , pp. 59-68
    • Bourtchuladze, R.1    Frenguelli, B.2    Blendy, J.3    Cioffi, D.4    Schutz, G.5    Silva, A.J.6
  • 150
    • 0034122495 scopus 로고    scopus 로고
    • CREB couples neurotrophin signals to survival messages
    • S0896-6273(00)80866-1 [pii]
    • Finkbeiner S (2000) CREB couples neurotrophin signals to survival messages. Neuron 25(1):11-14, S0896-6273(00)80866-1 [pii]
    • (2000) Neuron , vol.25 , Issue.1 , pp. 11-14
    • Finkbeiner, S.1
  • 151
    • 0037392348 scopus 로고    scopus 로고
    • Targeting the CREB pathway for memory enhancers
    • nrd1061 [pii]
    • Tully T, Bourtchouladze R, Scott R, Tallman J (2003) Targeting the CREB pathway for memory enhancers. Nat Rev Drug Discov 2(4):267-277. doi:10.1038/nrd1061, nrd1061 [pii]
    • (2003) Nat Rev Drug Discov , vol.2 , Issue.4 , pp. 267-277
    • Tully, T.1    Bourtchouladze, R.2    Scott, R.3    Tallman, J.4
  • 153
    • 24144483438 scopus 로고    scopus 로고
    • BDNF function in adult synaptic plasticity: The synaptic consolidation hypothesis
    • S0301-0082(05)00066-3 [pii]
    • Bramham CR, Messaoudi E (2005) BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog Neurobiol 76(2):99-125. doi:10.1016/j.pneurobio.2005.06.003, S0301-0082(05)00066-3 [pii]
    • (2005) Prog Neurobiol , vol.76 , Issue.2 , pp. 99-125
    • Bramham, C.R.1    Messaoudi, E.2
  • 155
    • 0034137655 scopus 로고    scopus 로고
    • Signal transduction events elicited by natural products: Role of MAPK and caspase pathways in homeostatic response and induction of apoptosis
    • Kong AN, Yu R, Chen C, Mandlekar S, Primiano T (2000) Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis. Arch Pharm Res 23(1):1-16
    • (2000) Arch Pharm Res , vol.23 , Issue.1 , pp. 1-16
    • Kong, A.N.1    Yu, R.2    Chen, C.3    Mandlekar, S.4    Primiano, T.5
  • 156
    • 34249788691 scopus 로고    scopus 로고
    • (-)-epicatechin stimulates ERK-dependent cyclic AMP response element activity and upregulates GLUR2 in cortical neurons
    • Schroeter H, Bahia P, Spencer JPE, Sheppard O, Rattray M, Rice-Evans C, Williams RJ (2007) (-)-epicatechin stimulates ERK-dependent cyclic AMP response element activity and upregulates GLUR2 in cortical neurons. J Neurochem 101(6):1596-1606
    • (2007) J Neurochem , vol.101 , Issue.6 , pp. 1596-1606
    • Schroeter, H.1    Bahia, P.2    Spencer, J.3    Sheppard, O.4    Rattray, M.5    Rice-Evans, C.6    Williams, R.J.7
  • 157
    • 0035884625 scopus 로고    scopus 로고
    • Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3
    • Schroeter H, Spencer JP, Rice-Evans C, Williams RJ (2001) Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3. Biochem J 358(Pt 3):547-557
    • (2001) Biochem J , vol.358 , pp. 547-557
    • Schroeter, H.1    Spencer, J.P.2    Rice-Evans, C.3    Williams, R.J.4
  • 158
    • 20144371838 scopus 로고    scopus 로고
    • Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-term serum-deprived PC12 cells and promotes neurite outgrowth
    • Reznichenko L, Amit T, Youdim MB, Mandel S (2005) Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-term serum-deprived PC12 cells and promotes neurite outgrowth. J Neurochem 93(5):1157-1167
    • (2005) J Neurochem , vol.93 , Issue.5 , pp. 1157-1167
    • Reznichenko, L.1    Amit, T.2    Youdim, M.B.3    Mandel, S.4
  • 159
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos CJ, Matter WF, Hui KY, Brown RF (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269(7):5241-5248
    • (1994) J Biol Chem , vol.269 , Issue.7 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 160
    • 7244229656 scopus 로고    scopus 로고
    • BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development
    • 24/33/9366 [pii]
    • Schratt GM, Nigh EA, Chen WG, Hu L, Greenberg ME (2004) BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development. J Neurosci 24(33):7366-7377. doi:10.1523/JNEUROSCI.1739-04.2004, 24/33/9366 [pii]
    • (2004) J Neurosci , vol.24 , Issue.33 , pp. 7366-7377
    • Schratt, G.M.1    Nigh, E.A.2    Chen, W.G.3    Hu, L.4    Greenberg, M.E.5
  • 161
    • 0037133172 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes
    • 042693699 [pii]
    • Yin Y, Edelman GM, Vanderklish PW (2002) The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes. Proc Natl Acad Sci USA 99(4):2368-2373. doi:10.1073/pnas.042693699, 042693699 [pii]
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.4 , pp. 2368-2373
    • Yin, Y.1    Edelman, G.M.2    Vanderklish, P.W.3
  • 162
    • 0035425948 scopus 로고    scopus 로고
    • Arg3.1/Arc mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen-activated protein kinase/extracellular regulated kinase activation
    • 21/15/5484 [pii]
    • Waltereit R, Dammermann B, Wulff P, Scafidi J, Staubli U, Kauselmann G, Bundman M, Kuhl D (2001) Arg3.1/Arc mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen-activated protein kinase/extracellular regulated kinase activation. J Neurosci 21(15):5484-5493, 21/15/5484 [pii]
    • (2001) J Neurosci , vol.21 , Issue.15 , pp. 5484-5493
    • Waltereit, R.1    Dammermann, B.2    Wulff, P.3    Scafidi, J.4    Staubli, U.5    Kauselmann, G.6    Bundman, M.7    Kuhl, D.8
  • 163
    • 33645519220 scopus 로고    scopus 로고
    • Long-term administration of green tea catechins improves spatial cognition learning ability in rats
    • 136/4/1043 [pii]
    • Haque AM, Hashimoto M, Katakura M, Tanabe Y, Hara Y, Shido O (2006) Long-term administration of green tea catechins improves spatial cognition learning ability in rats. JNutr 136(4):1043-1047, 136/4/1043 [pii]
    • (2006) Jnutr , vol.136 , Issue.4 , pp. 1043-1047
    • Haque, A.M.1    Hashimoto, M.2    Katakura, M.3    Tanabe, Y.4    Hara, Y.5    Shido, O.6
  • 164
    • 0037163110 scopus 로고    scopus 로고
    • Nvolvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action
    • Levites Y, Amit T, Youdim MB, Mandel S (2002) Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action. J Biol Chem 277(34):30574-30580. doi:10.1074/jbc.M202832200M202832200 [pii]
    • (2002) J Biol Chem , vol.277 , Issue.34 , pp. 30574-30580
    • Levites, Y.1    Amit, T.2    Youdim, M.B.3    Mandel, S.4
  • 165
    • 0036316691 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones
    • Perkinton MS, Ip JK, Wood GL, Crossthwaite AJ, Williams RJ (2002) Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones. J Neurochem 80(2):239-254
    • (2002) J Neurochem , vol.80 , Issue.2 , pp. 239-254
    • Perkinton, M.S.1    Ip, J.K.2    Wood, G.L.3    Crossthwaite, A.J.4    Williams, R.J.5
  • 167
    • 0024550507 scopus 로고
    • Protein kinase C inhibition by plant flavonoids. Kinetic mechanisms and structure-activity relationships
    • 0006-2952(89)90309-2 [pii]
    • Ferriola PC, Cody V, Middleton E Jr (1989) Protein kinase C inhibition by plant flavonoids. Kinetic mechanisms and structure-activity relationships. Biochem Pharmacol 38(10):1617-1624, 0006-2952(89)90309-2 [pii]
    • (1989) Biochem Pharmacol , vol.38 , Issue.10 , pp. 1617-1624
    • Ferriola, P.C.1    Cody, V.2    Middleton, E.3
  • 168
    • 0026726483 scopus 로고
    • The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs
    • 0006-291X(92) 90792-J [pii]
    • Matter WF, Brown RF, Vlahos CJ (1992) The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs. Biochem Biophys Res Commun 186(2):624-631, 0006-291X(92) 90792-J [pii]
    • (1992) Biochem Biophys Res Commun , vol.186 , Issue.2 , pp. 624-631
    • Matter, W.F.1    Brown, R.F.2    Vlahos, C.J.3
  • 169
    • 84857122677 scopus 로고    scopus 로고
    • Regulation of NF-kB activity in astrocytes: Effects of flavonoids at dietary-relevant concentrations
    • Spilsbury A, Vauzour D, Spencer JP, Rattray M (2012) Regulation of NF-kB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations. Biochem Biophys Res Commun. 418(3):578-583
    • (2012) Biochem Biophys Res Commun , vol.418 , Issue.3 , pp. 578-583
    • Spilsbury, A.1    Vauzour, D.2    Spencer, J.P.3    Rattray, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.