Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Aβ1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus

Neuroscience

Volumn 163, Issue 3, 2009, Pages 741-749

  Li, Q ^a   Zhao, H F ^a   Zhang, Z F ^a   Liu, Z G ^a   Pei, X R ^a   Wang, J B ^a   Li, Y ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

A 1 42 oligomers; green tea catechins; learning and memory; Morris water maze

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CATECHIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DRINKING WATER; GREEN TEA EXTRACT; POSTSYNAPTIC DENSITY PROTEIN 95;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; HIPPOCAMPUS; LEARNING DISORDER; LOCOMOTION; LONG TERM MEMORY; LONG TERM POTENTIATION; MALE; MAZE TEST; MEMORY DISORDER; MOUSE; NERVE CELL PLASTICITY; NISSL STAINING; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENESCENCE; TASK PERFORMANCE; TREATMENT DURATION; TREATMENT OUTCOME; UPREGULATION;

AGING; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CAMELLIA SINENSIS; CATECHIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEARNING; MALE; MEMBRANE PROTEINS; MEMORY; MICE; MICE, INBRED STRAINS; MOTOR ACTIVITY; NEURONAL PLASTICITY; PEPTIDE FRAGMENTS; PHOSPHORYLATION; SPATIAL BEHAVIOR; SYNAPSES; TIME FACTORS; UP-REGULATION;

EID: 70149095473     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.07.014     Document Type: Article

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