Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins

Journal of Biological Chemistry

Volumn 280, Issue 9, 2005, Pages 7614-7623

  Taniguchi, Sayuri ^a,b   Suzuki, Nobuyuki ^c   Masuda, Masami ^a,d   Hisanaga, Shin Ichi ^d   Iwatsubo, Takeshi ^b   Goedert, Michel ^e   Hasegawa, Masato ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c DAIICHI SANKYO CO   (Japan)

^d TOKYO METROPOLITAN UNIVERSITY   (Japan)

^e MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DISEASES; ELECTRON MICROSCOPY; FLUORESCENCE; GENES; OLIGOMERS; PHENOLS; PORPHYRINS;

MUTATIONS; NEURODEGENERATION; TAU PROTEINS; TAUOPATHIES;

PROTEINS;

AMPHOTERICIN B; AMYLOID BETA PROTEIN; APIGENIN; AZURE A; AZURE B; AZURE C; BENZOPHENONE DERIVATIVE; CHLORPROMAZINE; DAUNORUBICIN; EPICATECHIN GALLATE; FERRIC DEHYDROPORPHYRIN IX; FILIPIN; GOSSYPETIN; HEPARIN; MEPACRINE; MEPACRINE MUSTARD; METHYLENE BLUE; MYRICETIN; NYSTATIN; PERPHENAZINE; PHENOTHIAZINE; PHTHALOCYANINE; POLYPHENOL; PORPHYRIN; PORPHYRIN DERIVATIVE; PROMAZINE; PROPIONYLPROMAZINE; TAU PROTEIN; THIONINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTRON MICROSCOPY; FLUORESCENCE; IC 50; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY;

ANTIOXIDANTS; AZURE STAINS; BENZOPHENONES; BRAIN; CATECHIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; FLAVONOIDS; FLUORESCENT DYES; HEPARIN; HUMANS; METHYLENE BLUE; MICROTUBULES; MODELS, CHEMICAL; NEUROFIBRILLARY TANGLES; PHENOLS; PHENOTHIAZINES; PORPHYRINS; PROTEIN BINDING; QUINACRINE MUSTARD; TAU PROTEINS; TIME FACTORS;

EID: 14844303721     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M408714200     Document Type: Article

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