The effects of soy milk and isoflavone supplements on cognitive performance in healthy, postmenopausal women

Journal of Nutrition, Health and Aging

Volumn 11, Issue 2, 2007, Pages 155-164

  Fournier, Lisa R ^a   Ryan Borchers, T A ^a   Robison, L M ^a   Wiediger, M ^a   Park, J S ^a   Chew, B P ^a   Mcguire, M K ^a   Sclar, D A ^a   Skaer, T L ^a   Beerman, K A ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Cognition; Memory; Menopause; Phytoestrogen; Soy isoflavones

Indexed keywords

ISOFLAVONE DERIVATIVE;

ADULT; AGED; CLINICAL TRIAL; COGNITION; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HORMONE SUBSTITUTION; HUMAN; LONG TERM MEMORY; MENOPAUSAL SYNDROME; POSTMENOPAUSE; PRIORITY JOURNAL; SOYBEAN MILK; VERBAL MEMORY; VISUAL MEMORY; WORKING MEMORY;

EID: 34248172022     PISSN: 12797707     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (61)

1. Duff, S.J., & Hampson, E. A beneficial effect of estrogen on working memory in postmenopausal women taking hormone replacement therapy. Horm Behav. 2000;38:262-276.
2. Rossouw, J.E., Anderson, G.L., Prentice, R.L., et al. Risks and benefits of estrogen plus progestin in healthy post-menopusal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321-333.
3. Maki, P. M., Zonderman, A. B., & Resnick, S. M. Enhanced verbal memory in nondemented elderly women receiving hormone-replacement therapy. Am J Psychiatry. 2001;158:227-233.
4. Barentsen, R. The climacteric in the Netherlands: a review of Dutch studies on epidemiology, attitudes and use of hormone replacement therapy. Eur J Obst Gynecol Reprod Bio.1996; 64:S7-S11.
5. Breckwoldt, M., Keck, C., & Karck, U. Benefits and risks of hormone replacement therapy, J Steroid Biochem Mol Biol. 1995;53:205-208.
6. Beral, V., Million Study Collaborators. Breast cancer and hormone replacement therapy in the Million Women Study. Lancet. 2003;362:419-427.
7. Espeland, M.A., Rapp, S.R., Shumaker, S.A., Brunner, R.L., Manson, J.E., Sherwin, B.B., Hsia, J., Margolis, K.L., Hogan, P.E., Wallace, R., Dailey, M., Freeman, R., & Hays, J. Conjugated equine estrogens and global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study. JAMA. 2004;291:2959-2968.
8. Shumaker, S.A., Legault, C., Rapp, S.R., Thal, L., Wallace, R.B., Ockene, J.K., Hendrix, S.L., Jones, B.N., Assaf, A.R., Jackson, R.D., Kotchen, J.M., Wassertheil-Smoller, S. & Wactawski-Wende, J. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: The Women's Health Initiative Memory Study. JAMA. 2003;289:2651-2662.
9. Shumaker, S.A., Legault, C., Kuller, L., Rapp, S.R., Thal, L., Lane, D.S., Fillit, H., Stefanick, M.L., Hendrix, S.L., Lewis, C.E., Masaki, K., & Coker, L.H. Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study. JAMA. 2004;291:2947-2958.
10. Adlercreutz, H. Evolution, nutrition, intestinal microflora, and prevention of cancer: A hypothesis, Proc Soc Exp Biol Med.1997; 217:241-246.
11. Adlercreutz, H. Mazur, W., Bartels, P., Eloma, V., Watanabe, S., Wahala, K., Landstrom, M., Lundin, E., Bergh, A., Damber, J.E., Aman, P., Widmark, A., Johansson, A., Ahang, J.X., & Hallmans, G. Phytoestrogens and prostate disease. J Nutr. 2002;130:658S-659S.
12. Anthony, M.S., Clarkson, T.B., Bullock, B.C., & Wagner, J.D. Soy protein vs. soy phytoestrogens in the prevention of diet-induced coronary artery atherosclerosis of male cynomolgus monkeys. Arter Thromb Vas Biol.1996;17:2524-2531.
13. Barnes, S. The chemopreventive properties of soy isoflavonoids in animal models of breast cancer, Breast Cancer Res Treat. 1997;46:169-179.
14. Messina, M.J. Emerging evidence on the role of soy in reducing prostate cancer risk, Nut Rev. 2003; 61:117-131.
15. Clarkson, T.B., Anthony,n M.S., Williams, J.K., Honore, E.K., & Cline, J.M. The potential of soybean phytoestrogens for postmenopausal hormone replacement therapy. Proc Soc Exper Biol Med. 1998;217:365-368.
16. Setchell, K.D.R. Phytoestrogens: Biochemistry, physiology and implications for human health of soy isoflavones. Am J Clin Nutr. 1998;129:1333S-1346S.
17. Setchell, K.D.R., & Adlercreutz, H. Mammalian lingams and phytoestrogens recent studies on their formation, metabolism and biological role in health and disease, in: I.R. Rowland (Ed.), Role of the Gut Flora in Toxicity and Cancer, 1998. Academic Press, New York 315-345.
18. Wiseman, H. The therapeutic potential of phytoestrogens. Expert Opin Investig Drugs. 2000; 9:21829-1840.
19. Kuiper, G.G.J.M., Lemmen, J.G., Carlson, B., Corton, J.C., Safe, S.H., & Van der Saag, P.T. et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor B. Endocrinology. 1998;139:4252-4263.
20. McEwen, B., & Alves, S. Estrogen actions in the central nervous system, Endocr Rev. 1999; 20:279-307.
21. Sughrue, P.J., & Merchenthaler, I. Estrogen is more than just a "sex hormone": novel sites for estrogen action in the hippocampus and cerebral cortex, Front Neuroendocrinol. 2000;21:95-101.
22. Li, R., Shen, Y., Yang, L.B., Lue, L.F., Finch, C., & Rogers, J. Estrogen enhances uptake of amyloid beta-protein by microglia derived from the human cortex. J Neurochem. 2000; 75:1447-1454.
23. Osterlund, M.K., Gustafsson, J-A., Keller, E., & Hurd, Y.L. Estrogen Receptor β (ERβ) Messenger Ribonucleic Acid (mRNA) Expression within the Human Forebrain: Distinct Distribution Pattern to ER mRNA. J Clin Endocrinol Met. 2000;85:3840-3846.
24. White, L.R., Petrovitch, H., Ross, G.W., Masaki, K., Hardman, J., Nelson, J., Davis, D. & Markesbery, W. Brain aging and midlife tofu consumption, J Am Coll Nutr. 2000;19:242-255.
25. Pan, Y., Anthony, M.S., & Clarkson, T.B. Evidence for up-regulation of brain-derived neurotrophic factor mRNA by soy phytoestrogens in the frontal cortex of retired breeder female rats. Neuroscience Letters. 1999;261:1-4.
26. Pigott, S., & Milner, B. Memory for different aspects of complex visual scenes after unilateral temporal or frontal resection. Neuropsycholgia. 1993;20:1-15.
27. Squire, L.R. Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psych Rev. 1992;99:195-231.
28. Courtney S.M., Petit, L., Maisog, J.M., Ungerleider, L.G., & Haxby, J.V. An area specialized for spatial working memory in human frontal cortex. Science. 1998:279:1347-1351.
29. Potenza, M. N., Leung, H-C., Blumberg, H. P., Peterson, B. S., Fulbright, R. K., Lacadie, C M., Skudlarski, P., & Gore, J. C. An fMRI stroop task study of ventromedial prefrontal cortical function in pathological gamblers. Am J Psych. 2003;160:1990-1994.
30. Gazzaniga, M.S., Ivry, R.B., & Mangun, G.R. Cognitive Neuroscience: The Biology of the Mind. 2002. W.W. Norton & Company, Inc., New York: NY.
31. Lephart, E.D., West, T.W., Weber, S.K., Rhees, R.W., Setchell, K.D.R., Adlercreutz, H., Lund, T.D. Neurobehavioral effects of dietary soy phytoestrogens. Neurotoxicol and Teratol. 2002:24:5-16.
32. Lund, T.D., West, T.W., Tian, L.Y., Bu, L.H., Simmons, D.L., Setchell, K.D.R., Adlercreutz, H., & Lephart, E.D. Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens, Neurosci. 2001;2:1-13.
33. Pan, Y., Watson, A.M., & Carkson, T.B. Soy phytoestrogens improve radial arm maze performance in ovariectomized retired breeder rats and do not attenuate benefits of 17 beta-estradiol treatment. Menopause. 2000;7:230-235.
34. Kim, H., Xia, H., Li, L., & Gewin, J. Mini-review: Attenuation of neurodegeneration-relevant modifications of brain proteins by dietary soy, BioFactors. 2000;12:243-250.
35. Kim, H. Rationale for the use of soy phytoestrogens for neuroprotection. In Meskin, M.S., Bidlack, W.R., Davies, A.J., & Omaye, S.T., Ed: Phytochemicals in Nutrition and Health, 2002. Editor: CRC Press: Florida.
36. Duffy, R., Wiseman, H.. & File, S.E. Improved cognitive functions in postmenopausal women after 12 weeks of consumption of a soya extract containing isoflavones, Pharm Biochem Behav. 2003;75:721-729.
37. File, S.E., Hartley, D. E., Elsabagh, S., Duffy, R., Wiseman, H. Cognitive improvement after 6 weeks of soy supplements in postmenopausal women is limited to frontal lobe function. Menopause. 2005;12:193-201.
38. File, S.E., Jarrett, N., Fluck, E., Duffy, R., Casey, K., & Wiseman, H. Eating soya improves human memory, Psychopharmacol. 2001;157:430-436.
39. Kreijkamp-Kaspers, S., Kok, L., Grobbee, D.E., de Haan, E.H.F., Aleman, A., Lampe, J.W., van der Schouw, Y.T. Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: A randomized controlled trial, JAMA. 2004;292:65-74.
40. Kritz-Silverstein, D., Von Mühlen, D., Barrett-Connor, E., & Bressel, M.A.B. Isoflavones and cognitive function in older women: the Soy and Postmenopausal Health in Aging (SOPHIA) Study, J N Am Men Soc. 2003;10:196-202.
41. Zola-Morgan, S. & Squire, L. Neuroanatomy of memory. Ann Rev Neurosci. 1993;16:547-563.
42. Pihlajamäki M, Tanila H, Hänninen T, Könönen M, Laakso M, Partanen K, Soininen H, Aronen HJ. Verbal fluency activates the left medial temporal lobe: an fMRI study, Ann Neurol. 2000;47:470-476
43. Yaffe, K., Sawaya, G., Lieberburg, I., Grady, D. Estrogen therapy in postmenopausal women: effects on cognitive function and dementia. JAMA. 1998;279:688-695.
44. LeBlanc, E.S., Janowsky, J., Chan, B.K., Nelson, H.D. Hormone replacement therapy and cognition: systematic review and meta-analysis. JAMA. 2001;285:1489-1499.
45. Resnick, S.M., Maki, P.M., Golski, S., Kraut, M.A., & Zonderman, A.B. Effects of estrogen replacement therapy on PET cerebral blood flow and neuropsychological performance, Hor Behav. 1998;34:171-182.
46. Zachary, R.A. Shipley Institute of Living Scale. Revised Manual. Los Angeles, CA: Western Psychological Services. 1986.
47. Murphy, P.A., Song, T.T., Buseman, G., Barua, K., Beecher, G.R., Trainer, D., Holden, J. Isoflavones in retail and institutional soy foods, J Agric Food Chem. 1999;47:2697-2704.
48. Zhang, Y., Wang, G-J., Song, T.T., Murphy, P.A., Hendrich, S. Urinary disposition of the soybean isoflavones daidzein, genistein and glycitein differs among humans with moderate fecal isoflavone degradation activity. J Nutr. 1999;129:957-962.
49. Xu, X. Wang, H-J., Murphy, P.A., Cook, L., Hendrich, S. Daidzein is a more bioavailable soy milk isoflavone than is genistein in adult women, J Nutr.1994;124:825-832.
50. Beck, AT, Ward, C.H., Mendelson, M, Mock, J., Erbaugh, J. An inventory for measuring depression, Arch Gen Psych. 1961;4:561-571.
51. Stroop, J.R. Studies of interference in serial verbal reactions, J Exp Psych. 1935;18:643-662.
52. Petrides, M., Alivisatos, B., Meyer, E., & Evans, A.C. Functional activation of the human frontal cortex during the performance of verbal working memory tasks, Proc Natl Acad Sci USA. 1993;90:878-882.
53. Duff, S.J., & Hampson, E. A sex difference on a novel spatial working memory task in humans, Brain Cog. 2001;47:470-493.
54. Benton, A.L. The Revised Visual Retention Test: clinical and experimental applications (3rd Edition). 1963. Psychological Corporation. New York
55. Benton, A.L. Revised Visual Retention Test. 1974. Psychological Corp., New York.
56. Milner, B. Visual recognition and recall after right temporal-excision in man. Neuropsychol. 1968;6:191-209.
57. Wechsler, D. Wechsler Memory Scale-Revised. 1981. San Antonio, TX: Psychological Corporation.
58. Meyer, D. E., Mueller, S. T., Seymour, T. L., & Kieras, D. E. Brain loci of temporal coding and serial-order control for verbal working memory revealed by computational modeling and focal lesion analysis of memory-span performance, Annual meeting of the Cognitive Neuroscience Society. 2000.
59. Milner, B. Interhemispheric differences in the localization of psychological processes in man. Br Med Bull. 1971;27:272-277.
60. Uttl, B., Graf, P. Color word Stroop test performance across the adult life span. J Clin Exp Neuropsychol. 1979;19:1-16
61. Springer, M.V., McIntosh, A.R., Winocur, G., & Grady, C.L. The relation between brain activity during memory tasks and years of education in young and older adults. Neuropsychol. 2005;19:181-192