Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning

Nature Neuroscience

Volumn 1, Issue 7, 1998, Pages 595-601

  Impey, Soren ^a   Smith, Dave M ^a   Obrietan, Karl ^a   Donahue, Rachel ^a   Wade, Christian ^a   Storm, Daniel R ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP;

ANIMAL; ARTICLE; AVOIDANCE BEHAVIOR; C57BL MOUSE; CONDITIONING; DNA RESPONSIVE ELEMENT; FEAR; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETICS; HIPPOCAMPUS; LEARNING; MALE; MEMORY; MOUSE; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; AVOIDANCE LEARNING; CONDITIONING (PSYCHOLOGY); CYCLIC AMP; FEAR; GENE EXPRESSION; HIPPOCAMPUS; LEARNING; MALE; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RESPONSE ELEMENTS; TRANSCRIPTION, GENETIC;

EID: 0032195577     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/2830     Document Type: Article

References (50)

1. Kandel, E. R. Genes, synapses, and long-term memory. J. Cell. Physiol. 173, 124-125 (1997).
2. Dubnau, J. & Tully, T. Gene discovery in Drosophila: New insights for learning and memory. Annu. Rev. Neurosci. 21, 407-444 (1998).
3. Collingridge, G. L. & Bliss, T. V. Memories of NMDA receptors and LTP. Trends Neurosci. 18, 54-56 (1995).
4. Stevens, C. F. A million dollar question: Does LTP = memory? Neuron 20, 1-2 (1998).
5. Barondes, S. H. & Cohen, H. D. Arousal and the conversion of short-term to long-term memory. Proc. Natl. Acad. Sci. USA 61, 923-929 (1968).
6. Goelet, P., Castellucci, V. F., Schacher, S. & Kandel, E. R. The long and short of long-term memory- a molecular framework. Nature 322, 419-422 (1986).
7. Davis, H. P. & Squire, L. R. Protein synthesis and memory: a review. Psychol. Bull. 96, 518-559 (1984).
8. Tully, T., Preat, T., Boynton, S. C. & Del Vecchio, M. Genetic disection of consolidated memory in drosophila. Cell 79, 35-47 (1994).
9. Livingston, M. S., Sziber, P. P. & Quinn, W. G. Loss of calcium calmodulin responsiveness in adenylyl cyclase of rutabaga, a Drosophila learning mutant. Cell 37, 205-215 (1984).
10. Yovell, Y., Kandel, E. R., Dudai, Y. & Abrams, T. W. Biochemical correlates of short-term sensitization in Aplysia: temporal analysis of adenylate cyclase stimulation in a perfused-membrane preparation. Proc. Natl. Acad. Sci. USA 84, 9285-9289 (1987).
11. Silva, A. J., Paylor, R., Wehner, J. M. & Tonegawa, S. Impaired spatial learning in alpha calcium calmodulin kinase II mutant mice. Science 257, 206-210 (1992).
12. Wu, Z. L. et al. Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. Proc. Natl. Acad. Sci. USA 92, 220-224 (1995).
13. Abel, T., Nguyen, P. V., Barad, M., Deuel, T. A. S. & Kandel, E. R. Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell 88, 615-626 (1997).
14. Frey, U., Huang, Y. Y. & Kandel, E. R. Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons. Science 260, 1661-1664 (1993).
15. Impey, S. et al. Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus. Neuron 16, 973-982 (1996).
16. Sheng, M., McFadden, G. & Greenberg, M. E. Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4, 571-582 (1990).
17. Impey, S. et al. Crosstalk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. Neuron (in press).
18. Nguyen, P. V. & Kandel, E. R. A macromolecular synthesis-dependent late phase of long-term potentiation requiring cAMP in the medial perforant pathway of rat hippocampal slices. J. Neurosci. 16, 3189-3198 (1996).
19. Dash, P. K., Hochner, B. & Kandel, E. R. Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation. Nature 345, 718-721 (1990).
20. Martin, K. C. et al. Synapse-specific, long-form facilitation of Aplysia sensory to motor synapses: A function for local protein synthesis in memory storage. Cell 91, 927-938 (1997).
21. Yin, J. C. P. et al. Induction of a dominant negative CREB transgene specifically blocks long-term memory in drosophila. Cell 79, 49-58 (1994).
22. Yin, J. C., Del Vecchio, M., Zhou, H. & Tully, T. CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila. Cell 81, 107-115 (1995).
23. Bourtchuladze, R. et al. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell 79, 59-68 (1994).
24. Kogan, J. H. et al. Spaced training induces normal long-term memory in CREB mutant mice. Curr. Biol. 7, 1-11 (1997).
25. Phillips, R. G. & LeDoux, J. E. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav. Neurosci. 106, 274-285 (1992).
26. Kim, J. J. & Fanselow, M. S. Modality-specific retrograde amnesia of fear. Science 256, 675-677 (1992).
27. Chen, C., Kim, J. J., Thompson, R. F. & Tonegawa, S. Hippocampal lesions impair contextual fear conditioning in two strains of mice. Behav. Neurosci. 110, 1177-1180 (1996).
28. Logue, S. F., Paylor, R. & Wehner, J. M. Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task. Behav. Neurosci. 111, 104-113 (1997).
29. Fanselow, M. S. Conditioned and unconditional components of post-shock freezing. Pavlov. J. Biol. Sci. 15, 177-182 (1980).
30. Paylor, R., Tracy, R., Wehner, J. & Rudy, J. W. DBA/2 and C57BL/6 mice differ in contextual fear but not auditory fear conditioning. Behav. Neurosci. 108, 810-817 (1994).
31. Brindle, P., Nakajima, T. & Montminy, M. Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP. Proc. Natl. Acad. Sci. USA 92, 10521-10525 (1995).
32. Bito, H., Deisseroth, K. & Tsien, R. W. CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression. Cell 87, 1203-1214 (1996).
33. Davis, M. The role of the amygdala in fear and anxiety. Annu. Rev. Neurosci. 15, 353-375 (1992).
34. Maren, S., Aharonov, G. & Fanselow, M. S. Retrograde abolition of conditional fear after excitotoxic lesions in the basolateral amygdala of rats: absence of a temporal gradient. Behav. Neurosci. 110, 718-726 (1996).
35. Rogan, M. T., Staubli, U. V. & LeDoux, J. E. Fear conditioning induces associative long-term potentiation in the amygdala. Nature 390, 604-607 (1997).
36. Campeau, S. & Davis, M. The amygdala and fear conditioning: has the nut been cracked? Involvement of the central nucleus and basolateral complex of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli. Neuron 16, 237-240 (1996).
37. Helmstetter, F. J. & Bellgowan, P. S. Effects of muscimol applied to the basolateral amygdala on acquisition and expression of contextual fear conditioning in rats. Behav. Neurosci. 108, 1005-1009 (1994).
38. Stubley Weatherly, L., Harding, J. W. & Wright, J. W. Effects of discrete kainic acid-induced hippocampal lesions on spatial and contextual learning and memory in rats. Brain Res. 716, 29-38 (1996).
39. Lubow, R. E. Latent inhibition. Psychol. Bull. 79, 398-407 (1973).
40. Phillips, R. G. & LeDoux, J. E. Lesions of the fornix but not the entorhinal or perirhinal cortex interfere with contextual fear conditioning. J. Neurosci. 15, 5308-5315 (1995).
41. Good, M. & Honey, R. C. Dissociable effects of selective lesions to hippocampal subsystems on exploratory behavior, contextual learning, and spatial learning. Behav. Neurosci. 111, 487-493 (1997).
42. Yeckel, M. F. & Berger, T. W. Monosynaptic excitation of hippocampal CA1 pyramidal cells by afferents from the entorhinal cortex. Hippocampus 5, 108-114 (1995).
43. Moore, R.Y. & Bloom, F.E. Central catecholamine neuron systems: anatomy and physiology of the norepinephrine and epinephrine systems. Annu. Rev. Neurosci. 2, 113-168 (1979).
44. Dutar, P., Bassant, M. H., Senut, M. C. & Lamour, Y. The septohippocampal pathway: structure and function of a central cholinergic system. Physiol. Rev. 75, 393-427 (1995).
45. English, J. D. & Sweatt, J. D. A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation. J. Biol. Chem. 272, 19103-19106 (1997).
46. Brambilla, R. et al. A role for the Ras signalling pathway in synaptic transmission and long-term memory. Nature 390, 281-286 (1997).
47. Shieh, P. B., Hu, S. C., Bobb, K., Timmusk, T. & Ghosh, A. Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron 20, 727-740 (1998).
48. Tao, X., Finkbeiner, S., Arnold, D. B., Shaywitz, A. J. & Greenberg, M. E. Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron 20, 709-726 (1998).
49. Alberini, C. M., Ghirardi, M., Metz, R. & Kandel, E. R. C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia. Cell 76, 1099-1114 (1994).
50. Huang, Y. Y. et al. Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. Proc. Natl. Acad. Sci. USA 93, 8699-8704 (1996).