Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-κB activation

Biochemical Pharmacology

Volumn 59, Issue 11, 2000, Pages 1445-1457

  Chen, Yen Chou ^a   Yang, Ling Ling ^b   Lee, Tony J F ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cyclooxygenase 2; Inducible nitric oxide synthase; Lipopolysaccharide; Macrophages; Nuclear factor B; Oroxylin A; Polyphenolic compounds

Indexed keywords

ANTHRAQUINONE; CYCLOOXYGENASE 2; ELLAGITANNIN; EMODIN; FLAVONOID; GLUCOSE PENTAGALLATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; OROXYLIN A; PHYSCION; POLYPHENOL DERIVATIVE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHINESE HERB; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENCY; ENZYME INDUCTION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPSIS;

ANIMALS; ANTHRAQUINONES; CELLS, CULTURED; CYCLOOXYGENASE 2; EMODIN; FLAVONOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROLYZABLE TANNINS; ISOENZYMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHENOLS; POLYMERS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; TANNINS;

EID: 0034213030     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00255-0     Document Type: Article

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