Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons

Journal of Neurochemistry

Volumn 103, Issue 4, 2007, Pages 1355-1367

  Vauzour, David ^a   Vafeiadou, Katerina ^a   Rice Evans, Catherine ^b   Williams, Robert J ^b   Spencer, Jeremy P E ^a  

^a UNIVERSITY OF READING   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Apoptosis; Brain; Flavanoid; MAP kinase; Neuron; Oxidative stress

Indexed keywords

5 NITRO HESPERETIN; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE 3; CASPASE 9; FLAVANONE; FLAVONE DERIVATIVE; HESPERETIN; HESPERETIN 7 O BETA DELTA GLUCURONIDE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C JUN; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN CELL; ENZYME ACTIVATION; NERVE CELL DEGENERATION; NEUROPROTECTION; OXIDATIVE STRESS; OXIDATIVE STRESS INDUCED NEURONAL APOPTOSIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; ENZYME ACTIVATION; FLAVANONES; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURONS; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 35448949428     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04841.x     Document Type: Article

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