Role of P-glycoprotein in pharmacokinetics: Clinical implications

Clinical Pharmacokinetics

Volumn 42, Issue 1, 2003, Pages 59-98

  Lin, Jiunn H ^a   Yamazaki, Masayo ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; AMPRENAVIR; CHLOROTHIAZIDE; CIMETIDINE; CYCLOSPORIN; CYTOCHROME P450 3A4; DIGOXIN; ELACRIDAR; ETOPOSIDE; FUROSEMIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE TRANSPORTER 1; GLYCOPROTEIN P; INDINAVIR; KETOCONAZOLE; LOPERAMIDE; MESSENGER RNA; NELFINAVIR; NIFEDIPINE; ORGANIC ANION TRANSPORTER; PACLITAXEL; PROPRANOLOL; TACROLIMUS; UNINDEXED DRUG; VALSPODAR; VECURONIUM; VERAPAMIL; VINBLASTINE; ZOSUQUIDAR;

AREA UNDER THE CURVE; BILIARY EXCRETION; BLOOD BRAIN BARRIER; BLOOD PLACENTA BARRIER; DRUG ABSORPTION; DRUG BINDING SITE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG TRANSPORT; DRUG UPTAKE; ENZYME SPECIFICITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LIPOPHILICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN POLYMORPHISM; REVIEW; SPECIES DIFFERENCE; URINARY EXCRETION;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BIOTRANSFORMATION; DRUG INTERACTIONS; HUMANS; INTESTINAL ABSORPTION; P-GLYCOPROTEIN; PHARMACOKINETICS; SPECIES SPECIFICITY; TISSUE DISTRIBUTION;

EID: 0037229942     PISSN: 03125963     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003088-200342010-00003     Document Type: Review

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