메뉴 건너뛰기




Volumn 231, Issue 1, 2016, Pages 1-30

Current status and future perspectives: TSPO in steroid neuroendocrinology

Author keywords

Brain; Cholesterol; Hormone; Inflammation; Mitochondria; Nervous system; Neurosteroid; Spinal cord; Steroid

Indexed keywords

4' CHLORODIAZEPAM; BENZODIAZEPINE RECEPTOR; CHOLESTEROL; DIAZEPAM; EMAPUNIL; INDOLEACETAMIDE DERIVATIVE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROSTEROID; OCTADECANEUROPEPTIDE; ONO 2952; PROTEIN INHIBITOR; PROTOPORPHYRIN; STEROID HORMONE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID RECEPTOR; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; GABAERGIC RECEPTOR AFFECTING AGENT; TSPO PROTEIN, HUMAN;

EID: 84991491411     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-16-0241     Document Type: Review
Times cited : (32)

References (240)
  • 1
    • 79952625582 scopus 로고    scopus 로고
    • Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR)
    • Anderson LE, Dring AM, Hamel LD & Stoner MA 2011 Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR). Toxicology Letters 202 148-154. (doi:10.1016/j.toxlet.2011.02.004).
    • (2011) Toxicology Letters , vol.202 , pp. 148-154
    • Anderson, L.E.1    Dring, A.M.2    Hamel, L.D.3    Stoner, M.A.4
  • 2
    • 0021992304 scopus 로고
    • Depletion of peripheral-type benzodiazepine receptors after hypophysectomy in rat adrenal gland and testis
    • Anholt RR, De Souza EB, Kuhar MJ & Snyder SH 1985a Depletion of peripheral-type benzodiazepine receptors after hypophysectomy in rat adrenal gland and testis. European Journal of Pharmacology 110 41-46. (doi:10.1016/0014-2999(85)90026-3).
    • (1985) European Journal of Pharmacology , vol.110 , pp. 41-46
    • Anholt, R.R.1    De Souza, E.B.2    Kuhar, M.J.3    Snyder, S.H.4
  • 6
    • 84940467144 scopus 로고    scopus 로고
    • Enigmatic translocator protein (TSPO) and cellular stress regulation
    • Batoko H, Veljanovski V & Jurkiewicz P 2015 Enigmatic translocator protein (TSPO) and cellular stress regulation. Trends in Biochemical Sciences 40 497-503. (doi:10.1016/j.tibs.2015.07.001).
    • (2015) Trends in Biochemical Sciences , vol.40 , pp. 497-503
    • Batoko, H.1    Veljanovski, V.2    Jurkiewicz, P.3
  • 7
    • 21744447595 scopus 로고    scopus 로고
    • Neurosteroids: endogenous regulators of the GABA(A) receptor
    • Belelli D & Lambert JJ 2005 Neurosteroids: endogenous regulators of the GABA(A) receptor. Nature Reviews. Neuroscience 6 565-575. (doi:10.1038/nrn1703).
    • (2005) Nature Reviews. Neuroscience , vol.6 , pp. 565-575
    • Belelli, D.1    Lambert, J.J.2
  • 8
    • 0021264024 scopus 로고
    • Opposite effects of an agonist, RO5-4864, and an antagonist, PK 11195, of the peripheral type benzodiazepine binding sites on audiogenic seizures in DBA/2J mice
    • Benavides J, Guilloux F, Allam DE, Uzan A, Mizoule J, Renault C, Dubroeucq MC, Gueremy C & Le Fur G 1984 Opposite effects of an agonist, RO5-4864, and an antagonist, PK 11195, of the peripheral type benzodiazepine binding sites on audiogenic seizures in DBA/2J mice. Life Sciences 34 2613-2620. (doi:10.1016/0024-3205(84)90048-1).
    • (1984) Life Sciences , vol.34 , pp. 2613-2620
    • Benavides, J.1    Guilloux, F.2    Allam, D.E.3    Uzan, A.4    Mizoule, J.5    Renault, C.6    Dubroeucq, M.C.7    Gueremy, C.8    Le Fur, G.9
  • 9
    • 84939248947 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore: channel formation by F-ATP synthase, integration in signal transduction, and role in pathophysiology
    • Bernardi P, Rasola A, Forte M & Lippe G 2015 The mitochondrial permeability transition pore: channel formation by F-ATP synthase, integration in signal transduction, and role in pathophysiology. Physiological Reviews 95 1111-1155. (doi:10.1152/physrev.00001.2015).
    • (2015) Physiological Reviews , vol.95 , pp. 1111-1155
    • Bernardi, P.1    Rasola, A.2    Forte, M.3    Lippe, G.4
  • 10
    • 0027333450 scopus 로고
    • A 3D model of the peripheral benzodiazepine receptor and its implication in intra mitochondrial cholesterol transport
    • Bernassau JM, Reversat JL, Ferrara P, Caput D & Lefur G 1993 A 3D model of the peripheral benzodiazepine receptor and its implication in intra mitochondrial cholesterol transport. Journal of Molecular Graphics 11 236-244. (doi:10.1016/0263-7855(93)80003-A).
    • (1993) Journal of Molecular Graphics , vol.11 , pp. 236-244
    • Bernassau, J.M.1    Reversat, J.L.2    Ferrara, P.3    Caput, D.4    Lefur, G.5
  • 11
    • 0033902005 scopus 로고    scopus 로고
    • Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat
    • Bitran D, Foley M, Audette D, Leslie N & Frye CA 2000 Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat. Psychopharmacology 151 64-71. (doi:10.1007/s002130000471).
    • (2000) Psychopharmacology , vol.151 , pp. 64-71
    • Bitran, D.1    Foley, M.2    Audette, D.3    Leslie, N.4    Frye, C.A.5
  • 13
    • 33947118142 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor (PBR) aggregation and absence of steroidogenic acute regulatory protein (StAR)/PBR association in the mitochondrial membrane as determined by bioluminescence resonance energy transfer (BRET)
    • Bogan RL, Davis TL & Niswender GD 2007 Peripheral-type benzodiazepine receptor (PBR) aggregation and absence of steroidogenic acute regulatory protein (StAR)/PBR association in the mitochondrial membrane as determined by bioluminescence resonance energy transfer (BRET). Journal of Steroid Biochemistry and Molecular Biology 104 61-67. (doi:10.1016/j.jsbmb.2006.10.007).
    • (2007) Journal of Steroid Biochemistry and Molecular Biology , vol.104 , pp. 61-67
    • Bogan, R.L.1    Davis, T.L.2    Niswender, G.D.3
  • 14
    • 0037007628 scopus 로고    scopus 로고
    • Rapid regulation of steroidogenesis by mitochondrial protein import
    • Bose HS, Lingappa VR & Miller WL 2002 Rapid regulation of steroidogenesis by mitochondrial protein import. Nature 417 87-91. (doi:10.1038/417087a).
    • (2002) Nature , vol.417 , pp. 87-91
    • Bose, H.S.1    Lingappa, V.R.2    Miller, W.L.3
  • 15
    • 0027222663 scopus 로고
    • Inhibition of hormonestimulated steroidogenesis in cultured Leydig tumor cells by a cholesterol-linked phosphorothioate oligodeoxynucleotide antisense to diazepam-binding inhibitor
    • Boujrad N, Hudson JR Jr & Papadopoulos V 1993 Inhibition of hormonestimulated steroidogenesis in cultured Leydig tumor cells by a cholesterol-linked phosphorothioate oligodeoxynucleotide antisense to diazepam-binding inhibitor. PNAS 90 5728-5731. (doi:10.1073/pnas.90.12.5728).
    • (1993) PNAS , vol.90 , pp. 5728-5731
    • Boujrad, N.1    Hudson, J.R.2    Papadopoulos, V.3
  • 17
    • 84937517012 scopus 로고    scopus 로고
    • TSPO the unrested: challenged opinions of a resourceful mitochondrial protein
    • Campanella M 2015 TSPO the unrested: challenged opinions of a resourceful mitochondrial protein. Trends in Endocrinology and Metabolism 26 333-334. (doi:10.1016/j.tem.2015.05.003).
    • (2015) Trends in Endocrinology and Metabolism , vol.26 , pp. 333-334
    • Campanella, M.1
  • 18
    • 0030848810 scopus 로고    scopus 로고
    • Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia
    • Caron KM, Soo SC, Wetsel WC, Stocco DM, Clark BJ & Parker KL 1997 Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia. PNAS 94 11540-11545. (doi:10.1073/pnas.94.21.11540).
    • (1997) PNAS , vol.94 , pp. 11540-11545
    • Caron, K.M.1    Soo, S.C.2    Wetsel, W.C.3    Stocco, D.M.4    Clark, B.J.5    Parker, K.L.6
  • 19
    • 0027198085 scopus 로고
    • ACTH-induced mitochondrial DBI receptor (MDR) and diazepam binding inhibitor (DBI) expression in adrenals of hypophysectomized rats is not causeeffect related to its immediate steroidogenic action
    • Cavallaro S, Pani L, Guidotti A & Costa E 1993 ACTH-induced mitochondrial DBI receptor (MDR) and diazepam binding inhibitor (DBI) expression in adrenals of hypophysectomized rats is not causeeffect related to its immediate steroidogenic action. Life Sciences 53 1137-1147. (doi:10.1016/0024-3205(93)90550-M).
    • (1993) Life Sciences , vol.53 , pp. 1137-1147
    • Cavallaro, S.1    Pani, L.2    Guidotti, A.3    Costa, E.4
  • 21
    • 0029067030 scopus 로고
    • Gas chromatographicmass fragmentographic quantitation of 3 alpha-hydroxy-5 alphapregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats
    • Cheney DL, Uzunov D, Costa E & Guidotti A 1995 Gas chromatographicmass fragmentographic quantitation of 3 alpha-hydroxy-5 alphapregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats. Journal of Neuroscience 15 4641-4650.
    • (1995) Journal of Neuroscience , vol.15 , pp. 4641-4650
    • Cheney, D.L.1    Uzunov, D.2    Costa, E.3    Guidotti, A.4
  • 22
    • 0021802582 scopus 로고
    • Utilization of intramitochondrial membrane cholesterol by cytochrome P-450-dependent cholesterol side-chain cleavage reaction in bovine adrenocortical mitochondria: steroidogenic and non-steroidogenic pools of cholesterol in the mitochondrial inner membranes
    • Cheng B, Hsu DK & Kimura T 1985 Utilization of intramitochondrial membrane cholesterol by cytochrome P-450-dependent cholesterol side-chain cleavage reaction in bovine adrenocortical mitochondria: steroidogenic and non-steroidogenic pools of cholesterol in the mitochondrial inner membranes. Molecular and Cellular Endocrinology 40 233-243. (doi:10.1016/0303-7207(85)90179-0).
    • (1985) Molecular and Cellular Endocrinology , vol.40 , pp. 233-243
    • Cheng, B.1    Hsu, D.K.2    Kimura, T.3
  • 23
    • 84896333770 scopus 로고    scopus 로고
    • The translocator protein as a drug target in Alzheimer's disease
    • Chua SW, Kassiou M & Ittner LM 2014 The translocator protein as a drug target in Alzheimer's disease. Expert Review of Neurotherapeutics 14 439-448. (doi:10.1586/14737175.2014.896201).
    • (2014) Expert Review of Neurotherapeutics , vol.14 , pp. 439-448
    • Chua, S.W.1    Kassiou, M.2    Ittner, L.M.3
  • 24
    • 0018801471 scopus 로고
    • Topological studies of cytochromes P-450scc and P-45011 beta in bovine adrenocortical inner mitochondrial membranes. Effects of controlled tryptic digestion
    • Churchill PF & Kimura T 1979 Topological studies of cytochromes P-450scc and P-45011 beta in bovine adrenocortical inner mitochondrial membranes. Effects of controlled tryptic digestion. Journal of Biological Chemistry 254 10443-10448.
    • (1979) Journal of Biological Chemistry , vol.254 , pp. 10443-10448
    • Churchill, P.F.1    Kimura, T.2
  • 25
    • 0028104418 scopus 로고
    • The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)
    • Clark BJ, Wells J, King SR & Stocco DM 1994 The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). Journal of Biological Chemistry 269 28314-28322.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 28314-28322
    • Clark, B.J.1    Wells, J.2    King, S.R.3    Stocco, D.M.4
  • 26
    • 0033953033 scopus 로고    scopus 로고
    • Neurosteroids: biosynthesis and function of these novel neuromodulators
    • Compagnone NA & Mellon SH 2000 Neurosteroids: biosynthesis and function of these novel neuromodulators. Frontiers in Neuroendocrinology 21 1-56. (doi:10.1006/frne.1999.0188).
    • (2000) Frontiers in Neuroendocrinology , vol.21 , pp. 1-56
    • Compagnone, N.A.1    Mellon, S.H.2
  • 27
    • 0029012280 scopus 로고
    • Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis
    • Compagnone NA, Bulfone A, Rubenstein JL & Mellon SH 1995 Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis. Endocrinology 136 2689-2696. (doi:10.1210/en.136.6.2689).
    • (1995) Endocrinology , vol.136 , pp. 2689-2696
    • Compagnone, N.A.1    Bulfone, A.2    Rubenstein, J.L.3    Mellon, S.H.4
  • 28
    • 0343671487 scopus 로고
    • Characterization and measurement of dehydroepiandrosterone sulfate in rat brain
    • Corpechot C, Robel P, Axelson M, Sjovall J & Baulieu EE 1981 Characterization and measurement of dehydroepiandrosterone sulfate in rat brain. PNAS 78 4704-4707. (doi:10.1073/pnas.78.8.4704).
    • (1981) PNAS , vol.78 , pp. 4704-4707
    • Corpechot, C.1    Robel, P.2    Axelson, M.3    Sjovall, J.4    Baulieu, E.E.5
  • 30
    • 65349120620 scopus 로고    scopus 로고
    • Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain
    • Cosenza-Nashat M, Zhao ML, Suh HS, Morgan J, Natividad R, Morgello S & Lee SC 2009 Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain. Neuropathology and Applied Neurobiology 35 306-328. (doi:10.1111/j.1365-2990.2008.01006.x).
    • (2009) Neuropathology and Applied Neurobiology , vol.35 , pp. 306-328
    • Cosenza-Nashat, M.1    Zhao, M.L.2    Suh, H.S.3    Morgan, J.4    Natividad, R.5    Morgello, S.6    Lee, S.C.7
  • 31
    • 71949088753 scopus 로고    scopus 로고
    • The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals
    • Costa B, Pini S, Gabelloni P, Da Pozzo E, Abelli M, Lari L, Preve M, Lucacchini A, Cassano GB & Martini C 2009a The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals. Endocrinology 150 5438-5445. (doi:10.1210/en.2009-0752).
    • (2009) Endocrinology , vol.150 , pp. 5438-5445
    • Costa, B.1    Pini, S.2    Gabelloni, P.3    Da Pozzo, E.4    Abelli, M.5    Lari, L.6    Preve, M.7    Lucacchini, A.8    Cassano, G.B.9    Martini, C.10
  • 32
    • 63149093649 scopus 로고    scopus 로고
    • Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression
    • Costa B, Pini S, Martini C, Abelli M, Gabelloni P, Landi S, Muti M, Gesi C, Lari L, Cardini A, et al. 2009b Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression. Psychiatric Genetics 19 110-111. (doi:10.1097/ypg.0b013e32832080f6).
    • (2009) Psychiatric Genetics , vol.19 , pp. 110-111
    • Costa, B.1    Pini, S.2    Martini, C.3    Abelli, M.4    Gabelloni, P.5    Landi, S.6    Muti, M.7    Gesi, C.8    Lari, L.9    Cardini, A.10
  • 33
    • 78649713455 scopus 로고    scopus 로고
    • Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: stimulation of in vitro neurosteroid production affecting GABAA receptor activity
    • Costa B, Da Pozzo E, Chelli B, Simola N, Morelli M, Luisi M, Maccheroni M, Taliani S, Simorini F, Da Settimo F, et al. 2011 Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: stimulation of in vitro neurosteroid production affecting GABAA receptor activity. Psychoneuroendocrinology 36 463-472. (doi:10.1016/j. psyneuen.2010.07.021).
    • (2011) Psychoneuroendocrinology , vol.36 , pp. 463-472
    • Costa, B.1    Da Pozzo, E.2    Chelli, B.3    Simola, N.4    Morelli, M.5    Luisi, M.6    Maccheroni, M.7    Taliani, S.8    Simorini, F.9    Da Settimo, F.10
  • 36
    • 84959573495 scopus 로고    scopus 로고
    • The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis
    • Daugherty DJ, Chechneva O, Mayrhofer F & Deng W 2016 The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis. Scientific Reports 6 22556. (doi:10.1038/srep22556).
    • (2016) Scientific Reports , vol.6 , pp. 22556
    • Daugherty, D.J.1    Chechneva, O.2    Mayrhofer, F.3    Deng, W.4
  • 37
    • 0021944108 scopus 로고
    • Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis
    • De Souza EB, Anholt RR, Murphy KM, Snyder SH & Kuhar MJ 1985 Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis. Endocrinology 116 567-573. (doi:10.1210/endo-116-2-567).
    • (1985) Endocrinology , vol.116 , pp. 567-573
    • De Souza, E.B.1    Anholt, R.R.2    Murphy, K.M.3    Snyder, S.H.4    Kuhar, M.J.5
  • 38
    • 0000447628 scopus 로고
    • A morphological and histochemical study of the rat's adrenal cortex after hypoph ysectomy, with comments on the liver
    • Deane HW & Greep RO 1946 A morphological and histochemical study of the rat's adrenal cortex after hypoph ysectomy, with comments on the liver. American Journal of Anatomy 79 117-145. (doi:10.1002/(ISSN)1553-0795).
    • (1946) American Journal of Anatomy , vol.79 , pp. 117-145
    • Deane, H.W.1    Greep, R.O.2
  • 39
    • 33748750262 scopus 로고    scopus 로고
    • Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha
    • Ding X, Lichti K, Kim I, Gonzalez FJ & Staudinger JL 2006 Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha. Journal of Biological Chemistry 281 26540-26551. (doi:10.1074/jbc.M600931200).
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 26540-26551
    • Ding, X.1    Lichti, K.2    Kim, I.3    Gonzalez, F.J.4    Staudinger, J.L.5
  • 41
    • 84925400748 scopus 로고    scopus 로고
    • The non-benzodiazepine anxiolytic drug etifoxine causes a rapid, receptor-independent stimulation of neurosteroid biosynthesis
    • do Rego JL, Vaudry D & Vaudry H 2015 The non-benzodiazepine anxiolytic drug etifoxine causes a rapid, receptor-independent stimulation of neurosteroid biosynthesis. PLoS ONE 10 e0120473. (doi:10.1371/journal.pone.0120473).
    • (2015) PLoS ONE , vol.10
    • do Rego, J.L.1    Vaudry, D.2    Vaudry, H.3
  • 42
    • 0031906748 scopus 로고    scopus 로고
    • The endozepine triakontatetraneuropeptide diazepambinding inhibitor [17-50] stimulates neurosteroid biosynthesis in the frog hypothalamus
    • Do-Rego JL, Mensah-Nyagan AG, Feuilloley M, Ferrara P, Pelletier G & Vaudry H 1998 The endozepine triakontatetraneuropeptide diazepambinding inhibitor [17-50] stimulates neurosteroid biosynthesis in the frog hypothalamus. Neuroscience 83 555-570. (doi:10.1016/S0306-4522(97)00362-X).
    • (1998) Neuroscience , vol.83 , pp. 555-570
    • Do-Rego, J.L.1    Mensah-Nyagan, A.G.2    Feuilloley, M.3    Ferrara, P.4    Pelletier, G.5    Vaudry, H.6
  • 44
    • 71049143205 scopus 로고    scopus 로고
    • Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis
    • Fan J, Rone MB & Papadopoulos V 2009 Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis. Journal of Biological Chemistry 284 30484-30497. (doi:10.1074/jbc. M109.029876).
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 30484-30497
    • Fan, J.1    Rone, M.B.2    Papadopoulos, V.3
  • 45
    • 84860313330 scopus 로고    scopus 로고
    • Structural and functional evolution of the translocator protein (18 kDa)
    • Fan J, Lindemann P, Feuilloley MG & Papadopoulos V 2012 Structural and functional evolution of the translocator protein (18 kDa). Current Molecular Medicine 12 369-386. (doi:10.2174/1566524011207040369).
    • (2012) Current Molecular Medicine , vol.12 , pp. 369-386
    • Fan, J.1    Lindemann, P.2    Feuilloley, M.G.3    Papadopoulos, V.4
  • 46
    • 84931274608 scopus 로고    scopus 로고
    • Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation
    • Fan J, Campioli E, Midzak A, Culty M & Papadopoulos V 2015 Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation. PNAS 112 7261-7266. (doi:10.1073/pnas.1502670112).
    • (2015) PNAS , vol.112 , pp. 7261-7266
    • Fan, J.1    Campioli, E.2    Midzak, A.3    Culty, M.4    Papadopoulos, V.5
  • 47
    • 0000721214 scopus 로고
    • Protein synthesis and adrenocorticotropin responsiveness
    • Ferguson JJ Jr 1963 Protein synthesis and adrenocorticotropin responsiveness. Journal of Biological Chemistry 238 2754-2759.
    • (1963) Journal of Biological Chemistry , vol.238 , pp. 2754-2759
    • Ferguson, J.J.1
  • 49
    • 0020680096 scopus 로고
    • The anxiogenic action of Ro 5-4864 is reversed by phenytoin
    • File SE & Lister RG 1983 The anxiogenic action of Ro 5-4864 is reversed by phenytoin. Neuroscience Letters 35 93-96. (doi:10.1016/0304-3940(83)90532-3).
    • (1983) Neuroscience Letters , vol.35 , pp. 93-96
    • File, S.E.1    Lister, R.G.2
  • 50
    • 0022406721 scopus 로고
    • The effects of PK 11195, a ligand for benzodiazepine binding sites, in animal tests of anxiety and stress
    • File SE & Pellow S 1985 The effects of PK 11195, a ligand for benzodiazepine binding sites, in animal tests of anxiety and stress. Pharmacology Biochemistry and Behavior 23 737-741. (doi:10.1016/0091-3057(85)90064-4).
    • (1985) Pharmacology Biochemistry and Behavior , vol.23 , pp. 737-741
    • File, S.E.1    Pellow, S.2
  • 51
    • 0031740349 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in the adult rat central nervous system: colocalization of StAR, cytochrome P-450SCC (CYP XIA1), and 3beta-hydroxysteroid dehydrogenase in the rat brain
    • Furukawa A, Miyatake A, Ohnishi T & Ichikawa Y 1998 Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in the adult rat central nervous system: colocalization of StAR, cytochrome P-450SCC (CYP XIA1), and 3beta-hydroxysteroid dehydrogenase in the rat brain. Journal of Neurochemistry 71 2231-2238. (doi:10.1046/j.1471-4159.1998.71062231.x).
    • (1998) Journal of Neurochemistry , vol.71 , pp. 2231-2238
    • Furukawa, A.1    Miyatake, A.2    Ohnishi, T.3    Ichikawa, Y.4
  • 53
    • 0027978729 scopus 로고
    • The polypeptide diazepam-binding inhibitor and a higher affinity mitochondrial peripheral-type benzodiazepine receptor sustain constitutive steroidogenesis in the R2C Leydig tumor cell line
    • Garnier M, Boujrad N, Ogwuegbu SO, Hudson JR Jr & Papadopoulos V 1994 The polypeptide diazepam-binding inhibitor and a higher affinity mitochondrial peripheral-type benzodiazepine receptor sustain constitutive steroidogenesis in the R2C Leydig tumor cell line. Journal of Biological Chemistry 269 22105-22112.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 22105-22112
    • Garnier, M.1    Boujrad, N.2    Ogwuegbu, S.O.3    Hudson, J.R.4    Papadopoulos, V.5
  • 54
    • 84955479528 scopus 로고    scopus 로고
    • TSPO: kaleidoscopic 18-kDa amid biochemical pharmacology, control and targeting of mitochondria
    • Gatliff J & Campanella M 2016 TSPO: kaleidoscopic 18-kDa amid biochemical pharmacology, control and targeting of mitochondria. Biochemical Journal 473 107-121. (doi:10.1042/BJ20150899).
    • (2016) Biochemical Journal , vol.473 , pp. 107-121
    • Gatliff, J.1    Campanella, M.2
  • 55
    • 84922177703 scopus 로고    scopus 로고
    • TSPO interacts with VDAC1 and triggers a ROSmediated inhibition of mitochondrial quality control
    • Gatliff J, East D, Crosby J, Abeti R, Harvey R, Craigen W, Parker P & Campanella M 2014 TSPO interacts with VDAC1 and triggers a ROSmediated inhibition of mitochondrial quality control. Autophagy 10 2279-2296. (doi:10.4161/15548627.2014.991665).
    • (2014) Autophagy , vol.10 , pp. 2279-2296
    • Gatliff, J.1    East, D.2    Crosby, J.3    Abeti, R.4    Harvey, R.5    Craigen, W.6    Parker, P.7    Campanella, M.8
  • 57
    • 0034455530 scopus 로고    scopus 로고
    • Neurosteroid levels are increased in vivo after LPS treatment and negatively regulate LPS-induced TNF production
    • Ghezzi P, Santo ED, Sacco S, Foddi C, Barbaccia ML & Mennini T 2000 Neurosteroid levels are increased in vivo after LPS treatment and negatively regulate LPS-induced TNF production. European Cytokine Network 11 464-469.
    • (2000) European Cytokine Network , vol.11 , pp. 464-469
    • Ghezzi, P.1    Santo, E.D.2    Sacco, S.3    Foddi, C.4    Barbaccia, M.L.5    Mennini, T.6
  • 59
    • 24044550032 scopus 로고    scopus 로고
    • Progesterone increases oligodendroglial cell proliferation in rat cerebellar slice cultures
    • Ghoumari AM, Baulieu EE & Schumacher M 2005 Progesterone increases oligodendroglial cell proliferation in rat cerebellar slice cultures. Neuroscience 135 47-58. (doi:10.1016/j.neuroscience.2005.05.023).
    • (2005) Neuroscience , vol.135 , pp. 47-58
    • Ghoumari, A.M.1    Baulieu, E.E.2    Schumacher, M.3
  • 60
    • 84878322623 scopus 로고    scopus 로고
    • Chemical catalysis by the translocator protein (18 kDa)
    • Ginter C, Kiburu I & Boudker O 2013 Chemical catalysis by the translocator protein (18 kDa). Biochemistry 52 3609-3611. (doi:10.1021/bi400364z).
    • (2013) Biochemistry , vol.52 , pp. 3609-3611
    • Ginter, C.1    Kiburu, I.2    Boudker, O.3
  • 62
    • 0006003157 scopus 로고
    • Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma-aminobutyric acid type A receptor
    • Gray PW, Glaister D, Seeburg PH, Guidotti A & Costa E 1986 Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma-aminobutyric acid type A receptor. PNAS 83 7547-7551. (doi:10.1073/pnas.83.19.7547).
    • (1986) PNAS , vol.83 , pp. 7547-7551
    • Gray, P.W.1    Glaister, D.2    Seeburg, P.H.3    Guidotti, A.4    Costa, E.5
  • 63
    • 0026635087 scopus 로고
    • Regulation of pregnenolone synthesis in C6-2B glioma cells by 4'-chlorodiazepam
    • Guarneri P, Papadopoulos V, Pan B & Costa E 1992 Regulation of pregnenolone synthesis in C6-2B glioma cells by 4'-chlorodiazepam. PNAS 89 5118-5122. (doi:10.1073/pnas.89.11.5118).
    • (1992) PNAS , vol.89 , pp. 5118-5122
    • Guarneri, P.1    Papadopoulos, V.2    Pan, B.3    Costa, E.4
  • 66
    • 84938775711 scopus 로고    scopus 로고
    • Targeting mitochondrial energy metabolism with TSPO ligands
    • Gut P 2015 Targeting mitochondrial energy metabolism with TSPO ligands. Biochemical Society Transactions 43 537-542. (doi:10.1042/BST20150019).
    • (2015) Biochemical Society Transactions , vol.43 , pp. 537-542
    • Gut, P.1
  • 69
    • 84892410771 scopus 로고    scopus 로고
    • Investigating the interactions of the 18kDa translocator protein and its ligand PK11195 in planar lipid bilayers
    • Hatty CR, Le Brun AP, Lake V, Clifton LA, Liu GJ, James M & Banati RB 2014 Investigating the interactions of the 18kDa translocator protein and its ligand PK11195 in planar lipid bilayers. Biochimica et Biophysica Acta 1838 1019-1030. (doi:10.1016/j.bbamem.2013.12.013).
    • (2014) Biochimica et Biophysica Acta , vol.1838 , pp. 1019-1030
    • Hatty, C.R.1    Le Brun, A.P.2    Lake, V.3    Clifton, L.A.4    Liu, G.J.5    James, M.6    Banati, R.B.7
  • 70
    • 20844451376 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria
    • Hauet T, Yao ZX, Bose HS, Wall CT, Han Z, Li W, Hales DB, Miller WL, Culty M & Papadopoulos V 2005 Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria. Molecular Endocrinology 19 540-554. (doi:10.1210/me.2004-0307).
    • (2005) Molecular Endocrinology , vol.19 , pp. 540-554
    • Hauet, T.1    Yao, Z.X.2    Bose, H.S.3    Wall, C.T.4    Han, Z.5    Li, W.6    Hales, D.B.7    Miller, W.L.8    Culty, M.9    Papadopoulos, V.10
  • 71
    • 0018332597 scopus 로고
    • The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site
    • Haworth RA & Hunter DR 1979 The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site. Archives of Biochemistry and Biophysics 195 460-467. (doi:10.1016/0003-9861(79)90372-2).
    • (1979) Archives of Biochemistry and Biophysics , vol.195 , pp. 460-467
    • Haworth, R.A.1    Hunter, D.R.2
  • 72
    • 0004238525 scopus 로고
    • Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone
    • Hu ZY, Bourreau E, Jung-Testas I, Robel P & Baulieu EE 1987a Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone. PNAS 84 8215-8219. (doi:10.1073/pnas.84.23.8215).
    • (1987) PNAS , vol.84 , pp. 8215-8219
    • Hu, Z.Y.1    Bourreau, E.2    Jung-Testas, I.3    Robel, P.4    Baulieu, E.E.5
  • 73
    • 0004238525 scopus 로고
    • Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone
    • Hu ZY, Bourreau E, Jung-Testas I, Robel P & Baulieu EE 1987b Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone. PNAS 84 8215-8219. (doi:10.1073/pnas.84.23.8215).
    • (1987) PNAS , vol.84 , pp. 8215-8219
    • Hu, Z.Y.1    Bourreau, E.2    Jung-Testas, I.3    Robel, P.4    Baulieu, E.E.5
  • 75
    • 84874644958 scopus 로고    scopus 로고
    • Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells
    • Hulce JJ, Cognetta AB, Niphakis MJ, Tully SE & Cravatt BF 2013 Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells. Nature Methods 10 259-264. (doi:10.1038/nmeth.2368).
    • (2013) Nature Methods , vol.10 , pp. 259-264
    • Hulce, J.J.1    Cognetta, A.B.2    Niphakis, M.J.3    Tully, S.E.4    Cravatt, B.F.5
  • 76
    • 0018332596 scopus 로고
    • The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms
    • Hunter DR & Haworth RA 1979a The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms. Archives of Biochemistry and Biophysics 195 453-459. (doi:10.1016/0003-9861(79)90371-0).
    • (1979) Archives of Biochemistry and Biophysics , vol.195 , pp. 453-459
    • Hunter, D.R.1    Haworth, R.A.2
  • 77
    • 0018332598 scopus 로고
    • The Ca2+-induced membrane transition in mitochondria. III. Transitional Ca2+ release
    • Hunter DR & Haworth RA 1979b The Ca2+-induced membrane transition in mitochondria. III. Transitional Ca2+ release. Archives of Biochemistry and Biophysics 195 468-477. (doi:10.1016/0003-9861(79)90373-4).
    • (1979) Archives of Biochemistry and Biophysics , vol.195 , pp. 468-477
    • Hunter, D.R.1    Haworth, R.A.2
  • 78
    • 84861186845 scopus 로고    scopus 로고
    • Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway
    • Ishrat T, Sayeed I, Atif F, Hua F & Stein DG 2012 Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway. Neuroscience 210 442-450. (doi:10.1016/j.neuroscience.2012.03.008).
    • (2012) Neuroscience , vol.210 , pp. 442-450
    • Ishrat, T.1    Sayeed, I.2    Atif, F.3    Hua, F.4    Stein, D.G.5
  • 79
    • 84896998596 scopus 로고    scopus 로고
    • Structure of the mitochondrial translocator protein in complex with a diagnostic ligand
    • Jaremko L, Jaremko M, Giller K, Becker S & Zweckstetter M 2014 Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science 343 1363-1366. (doi:10.1126/science.1248725).
    • (2014) Science , vol.343 , pp. 1363-1366
    • Jaremko, L.1    Jaremko, M.2    Giller, K.3    Becker, S.4    Zweckstetter, M.5
  • 80
    • 84934287417 scopus 로고    scopus 로고
    • Structural Integrity of the A147T polymorph of mammalian TSPO
    • Jaremko M, Jaremko L, Giller K, Becker S & Zweckstetter M 2015a Structural Integrity of the A147T polymorph of mammalian TSPO. ChemBioChem 16 1483-1489. (doi:10.1002/cbic.201500217).
    • (2015) ChemBioChem , vol.16 , pp. 1483-1489
    • Jaremko, M.1    Jaremko, L.2    Giller, K.3    Becker, S.4    Zweckstetter, M.5
  • 82
    • 84961156384 scopus 로고    scopus 로고
    • Backbone and side-chain resonance assignment of the A147T polymorph of mouse TSPO in complex with a high-affinity radioligand
    • Jaremko M, Jaremko L, Giller K, Becker S & Zweckstetter M 2016 Backbone and side-chain resonance assignment of the A147T polymorph of mouse TSPO in complex with a high-affinity radioligand. Biomolecular NMR Assignments 10 79-83. (doi:10.1007/s12104-015-9642-y).
    • (2016) Biomolecular NMR Assignments , vol.10 , pp. 79-83
    • Jaremko, M.1    Jaremko, L.2    Giller, K.3    Becker, S.4    Zweckstetter, M.5
  • 83
    • 9444242160 scopus 로고    scopus 로고
    • Regulation of steroidogenesis and steroidogenic acute regulatory protein in R2C cells by DAX-1 (dosage-sensitive sex reversal, adrenal hypoplasia congenita, critical region on the X chromosome, gene-1)
    • Jo Y & Stocco DM 2004 Regulation of steroidogenesis and steroidogenic acute regulatory protein in R2C cells by DAX-1 (dosage-sensitive sex reversal, adrenal hypoplasia congenita, critical region on the X chromosome, gene-1). Endocrinology 145 5629-5637. (doi:10.1210/en.2004-0941).
    • (2004) Endocrinology , vol.145 , pp. 5629-5637
    • Jo, Y.1    Stocco, D.M.2
  • 84
    • 0024414366 scopus 로고
    • Pregnenolone, dehydroepiandrosterone, and their sulfate and fatty acid esters in the rat brain
    • Jo DH, Abdallah MA, Young J, Baulieu EE & Robel P 1989 Pregnenolone, dehydroepiandrosterone, and their sulfate and fatty acid esters in the rat brain. Steroids 54 287-297. (doi:10.1016/0039-128X(89)90003-2).
    • (1989) Steroids , vol.54 , pp. 287-297
    • Jo, D.H.1    Abdallah, M.A.2    Young, J.3    Baulieu, E.E.4    Robel, P.5
  • 85
    • 84860341342 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage-dependent anion channel-1
    • Joo HK, Lee YR, Lim SY, Lee EJ, Choi S, Cho EJ, Park MS, Ryoo S, Park JB & Jeon BH 2012 Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage-dependent anion channel-1. FEBS Letters 586 1349-1355. (doi:10.1016/j. febslet.2012.03.049).
    • (2012) FEBS Letters , vol.586 , pp. 1349-1355
    • Joo, H.K.1    Lee, Y.R.2    Lim, S.Y.3    Lee, E.J.4    Choi, S.5    Cho, E.J.6    Park, M.S.7    Ryoo, S.8    Park, J.B.9    Jeon, B.H.10
  • 86
    • 84958049427 scopus 로고    scopus 로고
    • The 18-kDa translocator protein inhibits vascular cell adhesion molecule-1 expression via inhibition of mitochondrial reactive oxygen species
    • Joo HK, Lee YR, Kang G, Choi S, Kim CS, Ryoo S, Park JB & Jeon BH 2015 The 18-kDa translocator protein inhibits vascular cell adhesion molecule-1 expression via inhibition of mitochondrial reactive oxygen species. Molecules and Cells 38 1064-1070.
    • (2015) Molecules and Cells , vol.38 , pp. 1064-1070
    • Joo, H.K.1    Lee, Y.R.2    Kang, G.3    Choi, S.4    Kim, C.S.5    Ryoo, S.6    Park, J.B.7    Jeon, B.H.8
  • 87
    • 0024414966 scopus 로고
    • Neurosteroids: biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells
    • Jung-Testas I, Hu ZY, Baulieu EE & Robel P 1989 Neurosteroids: biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells. Endocrinology 125 2083-2091. (doi:10.1210/endo-125-4-2083).
    • (1989) Endocrinology , vol.125 , pp. 2083-2091
    • Jung-Testas, I.1    Hu, Z.Y.2    Baulieu, E.E.3    Robel, P.4
  • 88
  • 89
    • 0013849907 scopus 로고
    • Enzymatic reduction of non-heme iron protein (adrenodoxin) by reduced nicotinamide adenine dinucleotide phosphate
    • Kimura T & Suzuki K 1965 Enzymatic reduction of non-heme iron protein (adrenodoxin) by reduced nicotinamide adenine dinucleotide phosphate. Biochemical and Biophysical Research Communications 20 373-379. (doi:10.1016/0006-291X(65)90585-1).
    • (1965) Biochemical and Biophysical Research Communications , vol.20 , pp. 373-379
    • Kimura, T.1    Suzuki, K.2
  • 91
    • 4644308387 scopus 로고    scopus 로고
    • The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain
    • King SR, Ginsberg SD, Ishii T, Smith RG, Parker KL & Lamb DJ 2004 The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain. Endocrinology 145 4775-4780. (doi:10.1210/en.2003-1740).
    • (2004) Endocrinology , vol.145 , pp. 4775-4780
    • King, S.R.1    Ginsberg, S.D.2    Ishii, T.3    Smith, R.G.4    Parker, K.L.5    Lamb, D.J.6
  • 92
    • 0027411220 scopus 로고
    • Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands
    • Kinnally KW, Zorov DB, Antonenko YN, Snyder SH, McEnery MW & Tedeschi H 1993 Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands. PNAS 90 1374-1378. (doi:10.1073/pnas.90.4.1374).
    • (1993) PNAS , vol.90 , pp. 1374-1378
    • Kinnally, K.W.1    Zorov, D.B.2    Antonenko, Y.N.3    Snyder, S.H.4    McEnery, M.W.5    Tedeschi, H.6
  • 93
    • 67349245212 scopus 로고    scopus 로고
    • Impact of sex steroids on neuroinflammatory processes and experimental multiple sclerosis
    • Kipp M & Beyer C 2009 Impact of sex steroids on neuroinflammatory processes and experimental multiple sclerosis. Frontiers in Neuroendocrinology 30 188-200. (doi:10.1016/j.yfrne.2009.04.004).
    • (2009) Frontiers in Neuroendocrinology , vol.30 , pp. 188-200
    • Kipp, M.1    Beyer, C.2
  • 96
    • 0020484516 scopus 로고
    • Purification and some properties of cytochrome P-450 specific for steroid 17 alphahydroxylation and C17-C20 bond cleavage from guinea pig adrenal microsomes
    • Kominami S, Shinzawa K & Takemori S 1982 Purification and some properties of cytochrome P-450 specific for steroid 17 alphahydroxylation and C17-C20 bond cleavage from guinea pig adrenal microsomes. Biochemical and Biophysical Research Communications 109 916-921. (doi:10.1016/0006-291X(82)92027-7).
    • (1982) Biochemical and Biophysical Research Communications , vol.109 , pp. 916-921
    • Kominami, S.1    Shinzawa, K.2    Takemori, S.3
  • 97
    • 0027428732 scopus 로고
    • Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo
    • Korneyev A, Pan BS, Polo A, Romeo E, Guidotti A & Costa E 1993 Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo. Journal of Neurochemistry 61 1515-1524. (doi:10.1111/j.1471-4159.1993.tb13647.x).
    • (1993) Journal of Neurochemistry , vol.61 , pp. 1515-1524
    • Korneyev, A.1    Pan, B.S.2    Polo, A.3    Romeo, E.4    Guidotti, A.5    Costa, E.6
  • 98
    • 77953560009 scopus 로고    scopus 로고
    • Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals
    • Korkhov VM, Sachse C, Short JM & Tate CG 2010 Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals. Structure 18 677-687. (doi:10.1016/j.str.2010.03.001).
    • (2010) Structure , vol.18 , pp. 677-687
    • Korkhov, V.M.1    Sachse, C.2    Short, J.M.3    Tate, C.G.4
  • 99
    • 0027488904 scopus 로고
    • Chemistry, binding affinities, and behavioral properties of a new class of "antineophobic" mitochondrial DBI receptor complex (mDRC) ligands
    • Kozikowski AP, Ma D, Brewer J, Sun S, Costa E, Romeo E & Guidotti A 1993 Chemistry, binding affinities, and behavioral properties of a new class of "antineophobic" mitochondrial DBI receptor complex (mDRC) ligands. Journal of Medicinal Chemistry 36 2908-2920. (doi:10.1021/jm00072a010).
    • (1993) Journal of Medicinal Chemistry , vol.36 , pp. 2908-2920
    • Kozikowski, A.P.1    Ma, D.2    Brewer, J.3    Sun, S.4    Costa, E.5    Romeo, E.6    Guidotti, A.7
  • 100
    • 0020636067 scopus 로고
    • Acute adrenocorticotropic hormone stimulation of adrenal corticosteroidogenesis. Discovery of a rapidly induced protein
    • Krueger RJ & Orme-Johnson NR 1983 Acute adrenocorticotropic hormone stimulation of adrenal corticosteroidogenesis. Discovery of a rapidly induced protein. Journal of Biological Chemistry 258 10159-10167.
    • (1983) Journal of Biological Chemistry , vol.258 , pp. 10159-10167
    • Krueger, R.J.1    Orme-Johnson, N.R.2
  • 101
    • 0025073860 scopus 로고
    • Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells
    • Krueger KE & Papadopoulos V 1990 Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells. Journal of Biological Chemistry 265 15015-15022.
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 15015-15022
    • Krueger, K.E.1    Papadopoulos, V.2
  • 102
    • 0033514002 scopus 로고    scopus 로고
    • Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesis
    • Lacor P, Gandolfo P, Tonon MC, Brault E, Dalibert I, Schumacher M, Benavides J & Ferzaz B 1999 Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesis. Brain Research 815 70-80. (doi:10.1016/S0006-8993(98)01105-6).
    • (1999) Brain Research , vol.815 , pp. 70-80
    • Lacor, P.1    Gandolfo, P.2    Tonon, M.C.3    Brault, E.4    Dalibert, I.5    Schumacher, M.6    Benavides, J.7    Ferzaz, B.8
  • 104
    • 0020522650 scopus 로고
    • Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]RO5-4864 and [3H]PK 11195, by thermodynamic studies
    • Le Fur G, Vaucher N, Perrier ML, Flamier A, Benavides J, Renault C, Dubroeucq MC, Gueremy C & Uzan A 1983 Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]RO5-4864 and [3H]PK 11195, by thermodynamic studies. Life Sciences 33 449-457. (doi:10.1016/0024-3205(83)90794-4).
    • (1983) Life Sciences , vol.33 , pp. 449-457
    • Le Fur, G.1    Vaucher, N.2    Perrier, M.L.3    Flamier, A.4    Benavides, J.5    Renault, C.6    Dubroeucq, M.C.7    Gueremy, C.8    Uzan, A.9
  • 107
    • 33845736814 scopus 로고    scopus 로고
    • Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin
    • Lee L, DeBono CA, Campagna DR, Young DC, Moody DB & Fleming MD 2007 Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin. Journal of Investigative Dermatology 127 16-23. (doi:10.1038/sj.jid.5700511).
    • (2007) Journal of Investigative Dermatology , vol.127 , pp. 16-23
    • Lee, L.1    DeBono, C.A.2    Campagna, D.R.3    Young, D.C.4    Moody, D.B.5    Fleming, M.D.6
  • 108
    • 79960402453 scopus 로고    scopus 로고
    • Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex
    • Lee K, Kerner J & Hoppel CL 2011a Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex. Journal of Biological Chemistry 286 25655-25662.
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 25655-25662
    • Lee, K.1    Kerner, J.2    Hoppel, C.L.3
  • 109
    • 78349279184 scopus 로고    scopus 로고
    • Astrocytes are GABAergic cells that modulate microglial activity
    • Lee M, Schwab C & McGeer PL 2011b Astrocytes are GABAergic cells that modulate microglial activity. Glia 59 152-165.
    • (2011) Glia , vol.59 , pp. 152-165
    • Lee, M.1    Schwab, C.2    McGeer, P.L.3
  • 110
    • 0031755752 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern
    • Li H & Papadopoulos V 1998 Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern. Endocrinology 139 4991-4997.
    • (1998) Endocrinology , vol.139 , pp. 4991-4997
    • Li, H.1    Papadopoulos, V.2
  • 111
    • 0035970108 scopus 로고    scopus 로고
    • Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide
    • Li H, Yao Z, Degenhardt B, Teper G & Papadopoulos V 2001 Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide. PNAS 98 1267-1272. (doi:10.1073/pnas.98.3.1267).
    • (2001) PNAS , vol.98 , pp. 1267-1272
    • Li, H.1    Yao, Z.2    Degenhardt, B.3    Teper, G.4    Papadopoulos, V.5
  • 112
    • 47949111469 scopus 로고    scopus 로고
    • The peripheral benzodiazepine receptor ligand 1-(2-chlorophenylmethylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor
    • Li L, Chen T, Stanton JD, Sueyoshi T, Negishi M & Wang H 2008 The peripheral benzodiazepine receptor ligand 1-(2-chlorophenylmethylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor. Molecular Pharmacology 74 443-453. (doi:10.1124/mol.108.046656).
    • (2008) Molecular Pharmacology , vol.74 , pp. 443-453
    • Li, L.1    Chen, T.2    Stanton, J.D.3    Sueyoshi, T.4    Negishi, M.5    Wang, H.6
  • 113
    • 0027770697 scopus 로고
    • The human peripheral benzodiazepine receptor gene: cloning and characterization of alternative splicing in normal tissues and in a patient with congenital lipoid adrenal hyperplasia
    • Lin D, Chang YJ, Strauss JF 3rd & Miller WL 1993 The human peripheral benzodiazepine receptor gene: cloning and characterization of alternative splicing in normal tissues and in a patient with congenital lipoid adrenal hyperplasia. Genomics 18 643-650. (doi:10.1016/S0888-7543(05)80367-2).
    • (1993) Genomics , vol.18 , pp. 643-650
    • Lin, D.1    Chang, Y.J.2    Strauss, J.F.3    Miller, W.L.4
  • 115
    • 84901463419 scopus 로고    scopus 로고
    • Genetic analysis of dTSPO, an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Aβ42-induced neurodegeneration
    • Lin R, Angelin A, Da Settimo F, Martini C, Taliani S, Zhu S & Wallace DC 2014 Genetic analysis of dTSPO, an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Aβ42-induced neurodegeneration. Aging Cell 13 507-518. (doi:10.1111/acel.12200).
    • (2014) Aging Cell , vol.13 , pp. 507-518
    • Lin, R.1    Angelin, A.2    Da Settimo, F.3    Martini, C.4    Taliani, S.5    Zhu, S.6    Wallace, D.C.7
  • 116
    • 84940731470 scopus 로고    scopus 로고
    • TSPO, a mitochondrial outer membrane protein, controls ethanol-related behaviors in Drosophila
    • Lin R, Rittenhouse D, Sweeney K, Potluri P & Wallace DC 2015 TSPO, a mitochondrial outer membrane protein, controls ethanol-related behaviors in Drosophila. PLoS Genetics 11 e1005366.
    • (2015) PLoS Genetics , vol.11
    • Lin, R.1    Rittenhouse, D.2    Sweeney, K.3    Potluri, P.4    Wallace, D.C.5
  • 117
    • 33845977384 scopus 로고    scopus 로고
    • Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis
    • Liu J, Rone MB & Papadopoulos V 2006 Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis. Journal of Biological Chemistry 281 38879-38893. (doi:10.1074/jbc. M608820200).
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 38879-38893
    • Liu, J.1    Rone, M.B.2    Papadopoulos, V.3
  • 119
    • 33746500168 scopus 로고    scopus 로고
    • GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development
    • Luo S, Mao C, Lee B & Lee AS 2006 GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development. Molecular and Cellular Biology 26 5688-5697. (doi:10.1128/MCB.00779-06).
    • (2006) Molecular and Cellular Biology , vol.26 , pp. 5688-5697
    • Luo, S.1    Mao, C.2    Lee, B.3    Lee, A.S.4
  • 120
    • 33847786718 scopus 로고    scopus 로고
    • Cytoplasmic domain of human myelin protein zero likely folded as beta-structure in compact myelin
    • Luo X, Sharma D, Inouye H, Lee D, Avila RL, Salmona M & Kirschner DA 2007 Cytoplasmic domain of human myelin protein zero likely folded as beta-structure in compact myelin. Biophysical Journal 92 1585-1597. (doi:10.1529/biophysj.106.094722).
    • (2007) Biophysical Journal , vol.92 , pp. 1585-1597
    • Luo, X.1    Sharma, D.2    Inouye, H.3    Lee, D.4    Avila, R.L.5    Salmona, M.6    Kirschner, D.A.7
  • 121
    • 84958166186 scopus 로고    scopus 로고
    • TSPO ligand PK11195 alleviates neuroinflammation and beta-amyloid generation induced by systemic LPS administration
    • Ma L, Zhang H, Liu N, Wang PQ, Guo WZ, Fu Q, Jiao LB, Ma YQ & Mi WD 2016 TSPO ligand PK11195 alleviates neuroinflammation and beta-amyloid generation induced by systemic LPS administration. Brain Research Bulletin 121 192-200. (doi:10.1016/j. brainresbull.2016.02.001).
    • (2016) Brain Research Bulletin , vol.121 , pp. 192-200
    • Ma, L.1    Zhang, H.2    Liu, N.3    Wang, P.Q.4    Guo, W.Z.5    Fu, Q.6    Jiao, L.B.7    Ma, Y.Q.8    Mi, W.D.9
  • 123
    • 19744378270 scopus 로고    scopus 로고
    • Mechanisms of mitochondrial apoptosis induced by peripheral benzodiazepine receptor ligands in human colorectal cancer cells
    • Maaser K, Sutter AP & Scherubl H 2005 Mechanisms of mitochondrial apoptosis induced by peripheral benzodiazepine receptor ligands in human colorectal cancer cells. Biochemical and Biophysical Research Communications 332 646-652. (doi:10.1016/j. bbrc.2005.05.005).
    • (2005) Biochemical and Biophysical Research Communications , vol.332 , pp. 646-652
    • Maaser, K.1    Sutter, A.P.2    Scherubl, H.3
  • 126
    • 0027531656 scopus 로고
    • Effect of heterologous expression of acyl-CoAbinding protein on acyl-CoA level and composition in yeast
    • Mandrup S, Jepsen R, Skott H, Rosendal J, Hojrup P, Kristiansen K & Knudsen J 1993 Effect of heterologous expression of acyl-CoAbinding protein on acyl-CoA level and composition in yeast. Biochemical Journal 290 369-374. (doi:10.1042/bj2900369).
    • (1993) Biochemical Journal , vol.290 , pp. 369-374
    • Mandrup, S.1    Jepsen, R.2    Skott, H.3    Rosendal, J.4    Hojrup, P.5    Kristiansen, K.6    Knudsen, J.7
  • 128
    • 0026591024 scopus 로고
    • Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier
    • McEnery MW, Snowman AM, Trifiletti RR & Snyder SH 1992 Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier. PNAS 89 3170-3174. (doi:10.1073/pnas.89.8.3170).
    • (1992) PNAS , vol.89 , pp. 3170-3174
    • McEnery, M.W.1    Snowman, A.M.2    Trifiletti, R.R.3    Snyder, S.H.4
  • 129
    • 0033562482 scopus 로고    scopus 로고
    • Progesterone derivatives are able to influence peripheral myelin protein 22 and P0 gene expression: possible mechanisms of action
    • Melcangi RC, Magnaghi V, Cavarretta I, Zucchi I, Bovolin P, D'Urso D & Martini L 1999 Progesterone derivatives are able to influence peripheral myelin protein 22 and P0 gene expression: possible mechanisms of action. Journal of Neuroscience Research 56 349-357. (doi:10.1002/(SICI)1097-4547(19990515)56:4<>1.0.CO;2-R).
    • (1999) Journal of Neuroscience Research , vol.56 , pp. 349-357
    • Melcangi, R.C.1    Magnaghi, V.2    Cavarretta, I.3    Zucchi, I.4    Bovolin, P.5    D'Urso, D.6    Martini, L.7
  • 130
    • 0027381252 scopus 로고
    • Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain
    • Mellon SH & Deschepper CF 1993 Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain. Brain Research 629 283-292. (doi:10.1016/0006-8993(93)91332-M).
    • (1993) Brain Research , vol.629 , pp. 283-292
    • Mellon, S.H.1    Deschepper, C.F.2
  • 131
    • 84938810813 scopus 로고    scopus 로고
    • Guwiyang Wurra-'Fire Mouse': a global gene knockout model for TSPO/PBR drug development, lossof-function and mechanisms of compensation studies
    • Middleton RJ, Liu GJ & Banati RB 2015 Guwiyang Wurra-'Fire Mouse': a global gene knockout model for TSPO/PBR drug development, lossof-function and mechanisms of compensation studies. Biochemical Society Transactions 43 553-558. (doi:10.1042/BST20150039).
    • (2015) Biochemical Society Transactions , vol.43 , pp. 553-558
    • Middleton, R.J.1    Liu, G.J.2    Banati, R.B.3
  • 132
    • 84906320367 scopus 로고    scopus 로고
    • Binding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterols
    • Midzak A & Papadopoulos V 2014 Binding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterols. Traffic 15 895-914. (doi:10.1111/tra.12177).
    • (2014) Traffic , vol.15 , pp. 895-914
    • Midzak, A.1    Papadopoulos, V.2
  • 135
    • 81855211988 scopus 로고    scopus 로고
    • Early steps in steroidogenesis: intracellular cholesterol trafficking
    • Miller WL & Bose HS 2011 Early steps in steroidogenesis: intracellular cholesterol trafficking. Journal of Lipid Research 52 2111-2135. (doi:10.1194/jlr.R016675).
    • (2011) Journal of Lipid Research , vol.52 , pp. 2111-2135
    • Miller, W.L.1    Bose, H.S.2
  • 138
    • 84891379545 scopus 로고    scopus 로고
    • Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis
    • Morohaku K, Pelton SH, Daugherty DJ, Butler WR, Deng W & Selvaraj V 2014 Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis. Endocrinology 155 89-97. (doi:10.1210/en.2013-1556).
    • (2014) Endocrinology , vol.155 , pp. 89-97
    • Morohaku, K.1    Pelton, S.H.2    Daugherty, D.J.3    Butler, W.R.4    Deng, W.5    Selvaraj, V.6
  • 139
    • 0024853180 scopus 로고
    • Mitochondrial benzodiazepine receptors regulate steroid biosynthesis
    • Mukhin AG, Papadopoulos V, Costa E & Krueger KE 1989 Mitochondrial benzodiazepine receptors regulate steroid biosynthesis. PNAS 86 9813-9816. (doi:10.1073/pnas.86.24.9813).
    • (1989) PNAS , vol.86 , pp. 9813-9816
    • Mukhin, A.G.1    Papadopoulos, V.2    Costa, E.3    Krueger, K.E.4
  • 140
    • 43849100475 scopus 로고    scopus 로고
    • Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding
    • Murail S, Robert JC, Coic YM, Neumann JM, Ostuni MA, Yao ZX, Papadopoulos V, Jamin N & Lacapere JJ 2008 Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding. Biochimica et Biophysica Acta 1778 1375-1381. (doi:10.1016/j.bbamem.2008.03.012).
    • (2008) Biochimica et Biophysica Acta , vol.1778 , pp. 1375-1381
    • Murail, S.1    Robert, J.C.2    Coic, Y.M.3    Neumann, J.M.4    Ostuni, M.A.5    Yao, Z.X.6    Papadopoulos, V.7    Jamin, N.8    Lacapere, J.J.9
  • 141
    • 0021105872 scopus 로고
    • Purification and properties of 17 alpha-hydroxylase from microsomes of pig adrenal: a second C21 side-chain cleavage system
    • Nakajin S, Shinoda M & Hall PF 1983 Purification and properties of 17 alpha-hydroxylase from microsomes of pig adrenal: a second C21 side-chain cleavage system. Biochemical and Biophysical Research Communications 111 512-517. (doi:10.1016/0006-291X(83)90336-4).
    • (1983) Biochemical and Biophysical Research Communications , vol.111 , pp. 512-517
    • Nakajin, S.1    Shinoda, M.2    Hall, P.F.3
  • 142
    • 58149215517 scopus 로고    scopus 로고
    • PBRL, a putative peripheral benzodiazepine receptor, in primitive erythropoiesis
    • Nakazawa F, Alev C, Shin M, Nakaya Y, Jakt LM & Sheng G 2009 PBRL, a putative peripheral benzodiazepine receptor, in primitive erythropoiesis. Gene Expression Patterns 9 114-121. (doi:10.1016/j. gep.2008.09.005).
    • (2009) Gene Expression Patterns , vol.9 , pp. 114-121
    • Nakazawa, F.1    Alev, C.2    Shin, M.3    Nakaya, Y.4    Jakt, L.M.5    Sheng, G.6
  • 144
    • 84890163806 scopus 로고    scopus 로고
    • Delayed hepatic adaptation to weaning in ACBP-/-mice is caused by disruption of the epidermal barrier
    • Neess D, Bek S, Bloksgaard M, Marcher AB, Faergeman NJ & Mandrup S 2013 Delayed hepatic adaptation to weaning in ACBP-/-mice is caused by disruption of the epidermal barrier. Cell Reports 5 1403-1412. (doi:10.1016/j.celrep.2013.11.010).
    • (2013) Cell Reports , vol.5 , pp. 1403-1412
    • Neess, D.1    Bek, S.2    Bloksgaard, M.3    Marcher, A.B.4    Faergeman, N.J.5    Mandrup, S.6
  • 147
    • 34548861265 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor-induced myocardial protection is mediated by inhibition of mitochondrial membrane permeabilization
    • Obame FN, Zini R, Souktani R, Berdeaux A & Morin D 2007 Peripheral benzodiazepine receptor-induced myocardial protection is mediated by inhibition of mitochondrial membrane permeabilization. Journal of Pharmacology and Experimental Therapeutics 323 336-345. (doi:10.1124/jpet.107.124255).
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.323 , pp. 336-345
    • Obame, F.N.1    Zini, R.2    Souktani, R.3    Berdeaux, A.4    Morin, D.5
  • 150
    • 0001507078 scopus 로고
    • Isolation from adrenal cortex of a nonheme iron protein and a flavoprotein functional as a reduced triphosphorpyridine nucleotidecytochrome P450 reductase
    • Omura T, Sanders E, Estabrook RW, Cooper DY & Rosenthal O 1966 Isolation from adrenal cortex of a nonheme iron protein and a flavoprotein functional as a reduced triphosphorpyridine nucleotidecytochrome P450 reductase. Archives of Biochemistry and Biophysics 117 660-673. (doi:10.1016/0003-9861(66)90108-1).
    • (1966) Archives of Biochemistry and Biophysics , vol.117 , pp. 660-673
    • Omura, T.1    Sanders, E.2    Estabrook, R.W.3    Cooper, D.Y.4    Rosenthal, O.5
  • 153
    • 77956493103 scopus 로고    scopus 로고
    • In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography
    • Ozaki H, Zoghbi SS, Hong J, Verma A, Pike VW, Innis RB & Fujita M 2010 In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography. Synapse 64 649-653. (doi:10.1002/syn.v64:8).
    • (2010) Synapse , vol.64 , pp. 649-653
    • Ozaki, H.1    Zoghbi, S.S.2    Hong, J.3    Verma, A.4    Pike, V.W.5    Innis, R.B.6    Fujita, M.7
  • 154
    • 4444317733 scopus 로고    scopus 로고
    • Cholesterol and the activity of bacterial toxins
    • Palmer M 2004 Cholesterol and the activity of bacterial toxins. FEMS Microbiology Letters 238 281-289. (doi:10.1111/j.1574-6968.2004. tb09768.x).
    • (2004) FEMS Microbiology Letters , vol.238 , pp. 281-289
    • Palmer, M.1
  • 155
    • 0026694918 scopus 로고
    • Inherited congenital adrenal hyperplasia in the rabbit: absent cholesterol side-chain cleavage cytochrome P450 gene expression
    • Pang S, Yang X, Wang M, Tissot R, Nino M, Manaligod J, Bullock LP & Mason JI 1992 Inherited congenital adrenal hyperplasia in the rabbit: absent cholesterol side-chain cleavage cytochrome P450 gene expression. Endocrinology 131 181-186.
    • (1992) Endocrinology , vol.131 , pp. 181-186
    • Pang, S.1    Yang, X.2    Wang, M.3    Tissot, R.4    Nino, M.5    Manaligod, J.6    Bullock, L.P.7    Mason, J.I.8
  • 156
    • 0031896355 scopus 로고    scopus 로고
    • Structure and function of the peripheral-type benzodiazepine receptor in steroidogenic cells
    • Papadopoulos V 1998 Structure and function of the peripheral-type benzodiazepine receptor in steroidogenic cells. Experimental Biology and Medicine 217 130-142. (doi:10.3181/00379727-217-44215).
    • (1998) Experimental Biology and Medicine , vol.217 , pp. 130-142
    • Papadopoulos, V.1
  • 157
    • 84891469290 scopus 로고    scopus 로고
    • On the role of the translocator protein (18-kDa) TSPO in steroid hormone biosynthesis
    • Papadopoulos V 2014 On the role of the translocator protein (18-kDa) TSPO in steroid hormone biosynthesis. Endocrinology 155 15-20. (doi:10.1210/en.2013-2033).
    • (2014) Endocrinology , vol.155 , pp. 15-20
    • Papadopoulos, V.1
  • 158
    • 68749119440 scopus 로고    scopus 로고
    • Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma
    • Papadopoulos V & Lecanu L 2009 Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma. Experimental Neurology 219 53-57. (doi:10.1016/j.expneurol.2009.04.016).
    • (2009) Experimental Neurology , vol.219 , pp. 53-57
    • Papadopoulos, V.1    Lecanu, L.2
  • 160
    • 0025254066 scopus 로고
    • The peripheraltype benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis
    • Papadopoulos V, Mukhin AG, Costa E & Krueger KE 1990 The peripheraltype benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis. Journal of Biological Chemistry 265 3772-3779.
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 3772-3779
    • Papadopoulos, V.1    Mukhin, A.G.2    Costa, E.3    Krueger, K.E.4
  • 161
    • 0025836777 scopus 로고
    • The role of diazepam binding inhibitor and its processing products at mitochondrial benzodiazepine receptors: regulation of steroid biosynthesis
    • Papadopoulos V, Berkovich A & Krueger KE 1991a The role of diazepam binding inhibitor and its processing products at mitochondrial benzodiazepine receptors: regulation of steroid biosynthesis. Neuropharmacology 30 1417-1423. (doi:10.1016/S0028-3908(11)80011-0).
    • (1991) Neuropharmacology , vol.30 , pp. 1417-1423
    • Papadopoulos, V.1    Berkovich, A.2    Krueger, K.E.3
  • 162
    • 0026051933 scopus 로고
    • Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors
    • Papadopoulos V, Berkovich A, Krueger KE, Costa E & Guidotti A 1991b Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors. Endocrinology 129 1481-1488.
    • (1991) Endocrinology , vol.129 , pp. 1481-1488
    • Papadopoulos, V.1    Berkovich, A.2    Krueger, K.E.3    Costa, E.4    Guidotti, A.5
  • 163
    • 0026649978 scopus 로고
    • Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor
    • Papadopoulos V, Guarneri P, Kreuger KE, Guidotti A & Costa E 1992 Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor. PNAS 89 5113-5117.
    • (1992) PNAS , vol.89 , pp. 5113-5117
    • Papadopoulos, V.1    Guarneri, P.2    Kreuger, K.E.3    Guidotti, A.4    Costa, E.5
  • 165
    • 0031451871 scopus 로고    scopus 로고
    • Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line
    • Papadopoulos V, Amri H, Li H, Boujrad N, Vidic B & Garnier M 1997b Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line. Journal of Biological Chemistry 272 32129-32135. (doi:10.1074/jbc.272.51.32129).
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 32129-32135
    • Papadopoulos, V.1    Amri, H.2    Li, H.3    Boujrad, N.4    Vidic, B.5    Garnier, M.6
  • 167
    • 84877937811 scopus 로고    scopus 로고
    • Cardioprotection by the TSPO ligand 4'-chlorodiazepam is associated with inhibition of mitochondrial accumulation of cholesterol at reperfusion
    • Paradis S, Leoni V, Caccia C, Berdeaux A & Morin D 2013 Cardioprotection by the TSPO ligand 4'-chlorodiazepam is associated with inhibition of mitochondrial accumulation of cholesterol at reperfusion. Cardiovascular Research 98 420-427. (doi:10.1093/cvr/cvt079).
    • (2013) Cardiovascular Research , vol.98 , pp. 420-427
    • Paradis, S.1    Leoni, V.2    Caccia, C.3    Berdeaux, A.4    Morin, D.5
  • 168
    • 84876758617 scopus 로고    scopus 로고
    • Metabolic pathways in immune cell activation and quiescence
    • Pearce EL & Pearce EJ 2013 Metabolic pathways in immune cell activation and quiescence. Immunity 38 633-643. (doi:10.1016/j. immuni.2013.04.005).
    • (2013) Immunity , vol.38 , pp. 633-643
    • Pearce, E.L.1    Pearce, E.J.2
  • 169
    • 0642352246 scopus 로고
    • Cholesterol side-chain cleavage in the rat adrenal cortex: isolation of a cycloheximide-sensitive activator peptide
    • Pedersen RC & Brownie AC 1983 Cholesterol side-chain cleavage in the rat adrenal cortex: isolation of a cycloheximide-sensitive activator peptide. PNAS 80 1882-1886. (doi:10.1073/pnas.80.7.1882).
    • (1983) PNAS , vol.80 , pp. 1882-1886
    • Pedersen, R.C.1    Brownie, A.C.2
  • 170
    • 0023177951 scopus 로고
    • Steroidogenesis-activator polypeptide isolated from a rat Leydig cell tumor
    • Pedersen RC & Brownie AC 1987 Steroidogenesis-activator polypeptide isolated from a rat Leydig cell tumor. Science 236 188-190. (doi:10.1126/science.3563495).
    • (1987) Science , vol.236 , pp. 188-190
    • Pedersen, R.C.1    Brownie, A.C.2
  • 171
    • 15044355642 scopus 로고    scopus 로고
    • In the ventral tegmental area picrotoxin blocks FGIN 1-27-induced increases in sexual behavior of rats and hamsters
    • Petralia SM & Frye CA 2005 In the ventral tegmental area picrotoxin blocks FGIN 1-27-induced increases in sexual behavior of rats and hamsters. Psychopharmacology 178 174-182. (doi:10.1007/s00213-004-2001-9).
    • (2005) Psychopharmacology , vol.178 , pp. 174-182
    • Petralia, S.M.1    Frye, C.A.2
  • 173
    • 0022918528 scopus 로고
    • Acute ACTH regulation of adrenal corticosteroid biosynthesis. Rapid accumulation of a phosphoprotein
    • Pon LA, Hartigan JA & Orme-Johnson NR 1986 Acute ACTH regulation of adrenal corticosteroid biosynthesis. Rapid accumulation of a phosphoprotein. Journal of Biological Chemistry 261 13309-13316.
    • (1986) Journal of Biological Chemistry , vol.261 , pp. 13309-13316
    • Pon, L.A.1    Hartigan, J.A.2    Orme-Johnson, N.R.3
  • 177
    • 0036939814 scopus 로고    scopus 로고
    • Regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of the cholesterol transfer proteins StAR and PBR
    • Rao RM, Jo Y, Babb-Tarbox M, Syapin PJ & Stocco DM 2002 Regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of the cholesterol transfer proteins StAR and PBR. Endocrine Research 28 387-394. (doi:10.1081/ERC-120016813).
    • (2002) Endocrine Research , vol.28 , pp. 387-394
    • Rao, R.M.1    Jo, Y.2    Babb-Tarbox, M.3    Syapin, P.J.4    Stocco, D.M.5
  • 178
    • 0037230367 scopus 로고    scopus 로고
    • Differential regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of SR-B1-mediated selective cholesteryl ester transport
    • Rao RM, Jo Y, Leers-Sucheta S, Bose HS, Miller WL, Azhar S & Stocco DM 2003 Differential regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of SR-B1-mediated selective cholesteryl ester transport. Biology of Reproduction 68 114-121.
    • (2003) Biology of Reproduction , vol.68 , pp. 114-121
    • Rao, R.M.1    Jo, Y.2    Leers-Sucheta, S.3    Bose, H.S.4    Miller, W.L.5    Azhar, S.6    Stocco, D.M.7
  • 179
    • 82755171864 scopus 로고    scopus 로고
    • An environment-dependent structural switch underlies the regulation of carnitine palmitoyltransferase 1A
    • Rao JN, Warren GZ, Estolt-Povedano S, Zammit VA & Ulmer TS 2011 An environment-dependent structural switch underlies the regulation of carnitine palmitoyltransferase 1A. Journal of Biological Chemistry 286 42545-42554. (doi:10.1074/jbc.M111.306951).
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 42545-42554
    • Rao, J.N.1    Warren, G.Z.2    Estolt-Povedano, S.3    Zammit, V.A.4    Ulmer, T.S.5
  • 180
    • 0028842242 scopus 로고
    • Modification of the photodynamic action of delta-aminolaevulinic acid (ALA) on rat pancreatoma cells by mitochondrial benzodiazepine receptor ligands
    • Ratcliffe SL & Matthews EK 1995 Modification of the photodynamic action of delta-aminolaevulinic acid (ALA) on rat pancreatoma cells by mitochondrial benzodiazepine receptor ligands. British Journal of Cancer 71 300-305. (doi:10.1038/bjc.1995.60).
    • (1995) British Journal of Cancer , vol.71 , pp. 300-305
    • Ratcliffe, S.L.1    Matthews, E.K.2
  • 182
    • 0002749123 scopus 로고
    • Intracellular cholesterol dynamics in steroidogenic cells: a contemporary view
    • Eds P Leung & Adashi EY. New York, NY, USA: Raven Press
    • Rennert H, Cheng YJ & Strauss JF 3rd 1993 Intracellular cholesterol dynamics in steroidogenic cells: a contemporary view. In The Ovary, pp 147-164. Eds P Leung & Adashi EY. New York, NY, USA: Raven Press.
    • (1993) The Ovary , pp. 147-164
    • Rennert, H.1    Cheng, Y.J.2    Strauss, J.F.3
  • 188
    • 33847742669 scopus 로고    scopus 로고
    • Cellular distribution of the GABAA receptor-modulating 3alpha-hydroxy, 5alpha-reduced pregnane steroids in the adult rat brain
    • Saalmann YB, Kirkcaldie MT, Waldron S & Calford MB 2007 Cellular distribution of the GABAA receptor-modulating 3alpha-hydroxy, 5alpha-reduced pregnane steroids in the adult rat brain. Journal of Neuroendocrinology 19 272-284. (doi:10.1111/j.1365-2826.2006.01527.x).
    • (2007) Journal of Neuroendocrinology , vol.19 , pp. 272-284
    • Saalmann, Y.B.1    Kirkcaldie, M.T.2    Waldron, S.3    Calford, M.B.4
  • 191
    • 0034078118 scopus 로고    scopus 로고
    • Modulation of GABAergic synaptic transmission by the nonbenzodiazepine anxiolytic etifoxine
    • Schlichter R, Rybalchenko V, Poisbeau P, Verleye M & Gillardin J 2000 Modulation of GABAergic synaptic transmission by the nonbenzodiazepine anxiolytic etifoxine. Neuropharmacology 39 1523-1535. (doi:10.1016/S0028-3908(99)00253-1).
    • (2000) Neuropharmacology , vol.39 , pp. 1523-1535
    • Schlichter, R.1    Rybalchenko, V.2    Poisbeau, P.3    Verleye, M.4    Gillardin, J.5
  • 192
    • 21744438122 scopus 로고    scopus 로고
    • Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: synthesis, biological evaluation and 3D-QSAR investigation
    • Selleri S, Gratteri P, Costagli C, Bonaccini C, Costanzo A, Melani F, Guerrini G, Ciciani G, Costa B, Spinetti F, et al. 2005 Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: synthesis, biological evaluation and 3D-QSAR investigation. Bioorganic & Medicinal Chemistry 13 4821-4834. (doi:10.1016/j.bmc.2005.05.015).
    • (2005) Bioorganic & Medicinal Chemistry , vol.13 , pp. 4821-4834
    • Selleri, S.1    Gratteri, P.2    Costagli, C.3    Bonaccini, C.4    Costanzo, A.5    Melani, F.6    Guerrini, G.7    Ciciani, G.8    Costa, B.9    Spinetti, F.10
  • 193
    • 84926316945 scopus 로고    scopus 로고
    • Minireview: translocator protein (TSPO) and steroidogenesis: a reappraisal
    • Selvaraj V, Stocco DM & Tu LN 2015 Minireview: translocator protein (TSPO) and steroidogenesis: a reappraisal. Molecular Endocrinology 29 490-501. (doi:10.1210/me.2015-1033).
    • (2015) Molecular Endocrinology , vol.29 , pp. 490-501
    • Selvaraj, V.1    Stocco, D.M.2    Tu, L.N.3
  • 194
    • 84983070470 scopus 로고    scopus 로고
    • Crucial role reported for TSPO in viability and steroidogenesis is a misconception
    • Selvaraj V, Tu LN & Stocco DM 2016 Crucial role reported for TSPO in viability and steroidogenesis is a misconception. Frontiers in Endocrinology 7 (doi:10.3389/fendo.2016.00091).
    • (2016) Frontiers in Endocrinology , vol.7
    • Selvaraj, V.1    Tu, L.N.2    Stocco, D.M.3
  • 196
    • 0032908756 scopus 로고    scopus 로고
    • 2-Phenyl-imidazo[1,2-a] pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats
    • Serra M, Madau P, Chessa MF, Caddeo M, Sanna E, Trapani G, Franco M, Liso G, Purdy RH, Barbaccia ML, et al. 1999 2-Phenyl-imidazo[1,2-a] pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats. British Journal of Pharmacology 127 177-187. (doi:10.1038/sj.bjp.0702530).
    • (1999) British Journal of Pharmacology , vol.127 , pp. 177-187
    • Serra, M.1    Madau, P.2    Chessa, M.F.3    Caddeo, M.4    Sanna, E.5    Trapani, G.6    Franco, M.7    Liso, G.8    Purdy, R.H.9    Barbaccia, M.L.10
  • 197
    • 0015905115 scopus 로고
    • Cytochrome P-450 from bovine adrenocortical mitochondria: an enzyme for the side chain cleavage of cholesterol. I. Purification and properties
    • Shikita M & Hall PF 1973 Cytochrome P-450 from bovine adrenocortical mitochondria: an enzyme for the side chain cleavage of cholesterol. I. Purification and properties. Journal of Biological Chemistry 248 5598-5604.
    • (1973) Journal of Biological Chemistry , vol.248 , pp. 5598-5604
    • Shikita, M.1    Hall, P.F.2
  • 198
    • 0141593516 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein in the rat brain: cellular distribution, developmental regulation and overexpression after injury
    • Sierra A, Lavaque E, Perez-Martin M, Azcoitia I, Hales DB & Garcia-Segura LM 2003 Steroidogenic acute regulatory protein in the rat brain: cellular distribution, developmental regulation and overexpression after injury. European Journal of Neuroscience 18 1458-1467. (doi:10.1046/j.1460-9568.2003.02872.x).
    • (2003) European Journal of Neuroscience , vol.18 , pp. 1458-1467
    • Sierra, A.1    Lavaque, E.2    Perez-Martin, M.3    Azcoitia, I.4    Hales, D.B.5    Garcia-Segura, L.M.6
  • 199
    • 84901008605 scopus 로고    scopus 로고
    • Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (TSPO)
    • Sileikyte J, Blachly-Dyson E, Sewell R, Carpi A, Menabo R, Di Lisa F, Ricchelli F, Bernardi P & Forte M 2014 Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (TSPO). Journal of Biological Chemistry 289 13769-13781. (doi:10.1074/jbc. M114.549634).
    • (2014) Journal of Biological Chemistry , vol.289 , pp. 13769-13781
    • Sileikyte, J.1    Blachly-Dyson, E.2    Sewell, R.3    Carpi, A.4    Menabo, R.5    Di Lisa, F.6    Ricchelli, F.7    Bernardi, P.8    Forte, M.9
  • 200
    • 0025783146 scopus 로고
    • Presence of identical mitochondrial proteins in unstimulated constitutive steroid-producing R2C rat Leydig tumor and stimulated nonconstitutive steroid-producing MA-10 mouse Leydig tumor cells
    • Stocco DM & Chen W 1991 Presence of identical mitochondrial proteins in unstimulated constitutive steroid-producing R2C rat Leydig tumor and stimulated nonconstitutive steroid-producing MA-10 mouse Leydig tumor cells. Endocrinology 128 1918-1926. (doi:10.1210/endo-128-4-1918).
    • (1991) Endocrinology , vol.128 , pp. 1918-1926
    • Stocco, D.M.1    Chen, W.2
  • 201
    • 0030047248 scopus 로고    scopus 로고
    • Regulation of the acute production of steroids in steroidogenic cells
    • Stocco DM & Clark BJ 1996 Regulation of the acute production of steroids in steroidogenic cells. Endocrine Reviews 17 221-244.
    • (1996) Endocrine Reviews , vol.17 , pp. 221-244
    • Stocco, D.M.1    Clark, B.J.2
  • 202
    • 0034717943 scopus 로고    scopus 로고
    • Intramitochondrial cholesterol transfer
    • Stocco DM 2000 Intramitochondrial cholesterol transfer. Biochimica et Biophysica Acta 1486 184-197. (doi:10.1016/S1388-1981(00)00056-1).
    • (2000) Biochimica et Biophysica Acta , vol.1486 , pp. 184-197
    • Stocco, D.M.1
  • 204
    • 26244457184 scopus 로고    scopus 로고
    • Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors. Synergistic antiproliferative action with ligands of the peripheral benzodiazepine receptor
    • Sutter AP, Maaser K, Hopfner M, Huether A, Schuppan D & Scherubl H 2005 Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors. Synergistic antiproliferative action with ligands of the peripheral benzodiazepine receptor. Journal of Hepatology 43 808-816. (doi:10.1016/j. jhep.2005.04.010).
    • (2005) Journal of Hepatology , vol.43 , pp. 808-816
    • Sutter, A.P.1    Maaser, K.2    Hopfner, M.3    Huether, A.4    Schuppan, D.5    Scherubl, H.6
  • 205
    • 0028362187 scopus 로고
    • Induction of peripheral-type benzodiazepine receptors during differentiation of mouse erythroleukemia cells. A possible involvement of these receptors in heme biosynthesis
    • Taketani S, Kohno H, Okuda M, Furukawa T & Tokunaga R 1994 Induction of peripheral-type benzodiazepine receptors during differentiation of mouse erythroleukemia cells. A possible involvement of these receptors in heme biosynthesis. Journal of Biological Chemistry 269 7527-7531.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 7527-7531
    • Taketani, S.1    Kohno, H.2    Okuda, M.3    Furukawa, T.4    Tokunaga, R.5
  • 206
    • 0025876996 scopus 로고
    • Localization of peripheral benzodiazepine binding sites and diazepam-binding inhibitor (DBI) mRNA in mammary glands and dimethylbenz(a) antracene (DMBA)-induced mammary tumors in the rat
    • Tong Y, Rheaume E, Simard J & Pelletier G 1991 Localization of peripheral benzodiazepine binding sites and diazepam-binding inhibitor (DBI) mRNA in mammary glands and dimethylbenz(a) antracene (DMBA)-induced mammary tumors in the rat. Regulatory Peptides 33 263-273. (doi:10.1016/0167-0115(91)90229-A).
    • (1991) Regulatory Peptides , vol.33 , pp. 263-273
    • Tong, Y.1    Rheaume, E.2    Simard, J.3    Pelletier, G.4
  • 207
    • 0028018037 scopus 로고
    • Localization of diazepam-binding inhibitor and peripheral type benzodiazepine binding sites in the rat ovary
    • Toranzo D, Tong Y, Tonon MC, Vaudry H & Pelletier G 1994 Localization of diazepam-binding inhibitor and peripheral type benzodiazepine binding sites in the rat ovary. Anatomy and Embryology 190 383-388.
    • (1994) Anatomy and Embryology , vol.190 , pp. 383-388
    • Toranzo, D.1    Tong, Y.2    Tonon, M.C.3    Vaudry, H.4    Pelletier, G.5
  • 208
    • 40949135299 scopus 로고    scopus 로고
    • Immunohistochemical identification of cells expressing steroidogenic enzymes cytochrome P450scc and P450 aromatase in taste buds of rat circumvallate papillae
    • Toyoshima K, Seta Y, Toyono T & Kataoka S 2007 Immunohistochemical identification of cells expressing steroidogenic enzymes cytochrome P450scc and P450 aromatase in taste buds of rat circumvallate papillae. Archives of Histology and Cytology 70 215-224. (doi:10.1679/aohc.70.215).
    • (2007) Archives of Histology and Cytology , vol.70 , pp. 215-224
    • Toyoshima, K.1    Seta, Y.2    Toyono, T.3    Kataoka, S.4
  • 209
    • 0033598378 scopus 로고    scopus 로고
    • Novel 2-phenylimidazo[1,2-a] pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies
    • Trapani G, Franco M, Latrofa A, Ricciardi L, Carotti A, Serra M, Sanna E, Biggio G & Liso G 1999 Novel 2-phenylimidazo[1,2-a] pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies. Journal of Medicinal Chemistry 42 3934-3941. (doi:10.1021/jm991035g).
    • (1999) Journal of Medicinal Chemistry , vol.42 , pp. 3934-3941
    • Trapani, G.1    Franco, M.2    Latrofa, A.3    Ricciardi, L.4    Carotti, A.5    Serra, M.6    Sanna, E.7    Biggio, G.8    Liso, G.9
  • 210
    • 19944429835 scopus 로고    scopus 로고
    • Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands
    • Trapani G, Laquintana V, Denora N, Trapani A, Lopedota A, Latrofa A, Franco M, Serra M, Pisu MG, Floris I, et al. 2005 Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands. Journal of Medicinal Chemistry 48 292-305. (doi:10.1021/jm049610q).
    • (2005) Journal of Medicinal Chemistry , vol.48 , pp. 292-305
    • Trapani, G.1    Laquintana, V.2    Denora, N.3    Trapani, A.4    Lopedota, A.5    Latrofa, A.6    Franco, M.7    Serra, M.8    Pisu, M.G.9    Floris, I.10
  • 211
    • 0034064138 scopus 로고    scopus 로고
    • Structure and lipid transport mechanism of a StAR-related domain
    • Tsujishita Y & Hurley JH 2000 Structure and lipid transport mechanism of a StAR-related domain. Nature Structural Biology 7 408-414. (doi:10.1038/75192).
    • (2000) Nature Structural Biology , vol.7 , pp. 408-414
    • Tsujishita, Y.1    Hurley, J.H.2
  • 213
    • 84907293074 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis
    • Tu LN, Morohaku K, Manna PR, Pelton SH, Butler WR, Stocco DM & Selvaraj V 2014 Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis. Journal of Biological Chemistry 289 27444-27454. (doi:10.1074/jbc.M114.578286).
    • (2014) Journal of Biological Chemistry , vol.289 , pp. 27444-27454
    • Tu, L.N.1    Morohaku, K.2    Manna, P.R.3    Pelton, S.H.4    Butler, W.R.5    Stocco, D.M.6    Selvaraj, V.7
  • 214
    • 84923870787 scopus 로고    scopus 로고
    • PK11195 effect on steroidogenesis is not mediated through the translocator protein (TSPO)
    • Tu LN, Zhao AH, Stocco DM & Selvaraj V 2015 PK11195 effect on steroidogenesis is not mediated through the translocator protein (TSPO). Endocrinology 156 1033-1039. (doi:10.1210/en.2014-1707).
    • (2015) Endocrinology , vol.156 , pp. 1033-1039
    • Tu, L.N.1    Zhao, A.H.2    Stocco, D.M.3    Selvaraj, V.4
  • 215
    • 84960532896 scopus 로고    scopus 로고
    • Translocator protein (TSPO) affects mitochondrial fatty acid oxidation in steroidogenic cells
    • Tu LN, Zhao AH, Hussein M, Stocco DM & Selvaraj V 2016 Translocator protein (TSPO) affects mitochondrial fatty acid oxidation in steroidogenic cells. Endocrinology 157 1110-1121. (doi:10.1210/en.2015-1795).
    • (2016) Endocrinology , vol.157 , pp. 1110-1121
    • Tu, L.N.1    Zhao, A.H.2    Hussein, M.3    Stocco, D.M.4    Selvaraj, V.5
  • 217
    • 36349004814 scopus 로고    scopus 로고
    • Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats
    • Ugale RR, Sharma AN, Kokare DM, Hirani K, Subhedar NK & Chopde CT 2007 Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats. Brain Research 1184 193-201. (doi:10.1016/j. brainres.2007.09.041).
    • (2007) Brain Research , vol.1184 , pp. 193-201
    • Ugale, R.R.1    Sharma, A.N.2    Kokare, D.M.3    Hirani, K.4    Subhedar, N.K.5    Chopde, C.T.6
  • 218
    • 0032704106 scopus 로고    scopus 로고
    • Interactions of etifoxine with the chloride channel coupled to the GABA(A) receptor complex
    • Verleye M, Schlichter R & Gillardin JM 1999 Interactions of etifoxine with the chloride channel coupled to the GABA(A) receptor complex. Neuroreport 10 3207-3210. (doi:10.1097/00001756-199910190-00015).
    • (1999) Neuroreport , vol.10 , pp. 3207-3210
    • Verleye, M.1    Schlichter, R.2    Gillardin, J.M.3
  • 220
    • 0042074645 scopus 로고
    • Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor
    • Verma A, Nye JS & Snyder SH 1987 Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor. PNAS 84 2256-2260. (doi:10.1073/pnas.84.8.2256).
    • (1987) PNAS , vol.84 , pp. 2256-2260
    • Verma, A.1    Nye, J.S.2    Snyder, S.H.3
  • 221
    • 24344509286 scopus 로고    scopus 로고
    • Differential expression of the peripheral benzodiazepine receptor and gremlin during adipogenesis
    • Wade FM, Wakade C, Mahesh VB & Brann DW 2005 Differential expression of the peripheral benzodiazepine receptor and gremlin during adipogenesis. Obesity Research 13 818-822. (doi:10.1038/oby.2005.93).
    • (2005) Obesity Research , vol.13 , pp. 818-822
    • Wade, F.M.1    Wakade, C.2    Mahesh, V.B.3    Brann, D.W.4
  • 222
    • 27744574711 scopus 로고    scopus 로고
    • PK11195, a peripheral benzodiazepine receptor (pBR) ligand, broadly blocks drug efflux to chemosensitize leukemia and myeloma cells by a pBR-independent, direct transportermodulating mechanism
    • Walter RB, Pirga JL, Cronk MR, Mayer S, Appelbaum FR & Banker DE 2005 PK11195, a peripheral benzodiazepine receptor (pBR) ligand, broadly blocks drug efflux to chemosensitize leukemia and myeloma cells by a pBR-independent, direct transportermodulating mechanism. Blood 106 3584-3593. (doi:10.1182/blood-2005-02-0711).
    • (2005) Blood , vol.106 , pp. 3584-3593
    • Walter, R.B.1    Pirga, J.L.2    Cronk, M.R.3    Mayer, S.4    Appelbaum, F.R.5    Banker, D.E.6
  • 223
    • 18644371723 scopus 로고    scopus 로고
    • The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression
    • Wang JM, Johnston PB, Ball BG & Brinton RD 2005 The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression. Journal of Neuroscience 25 4706-4718. (doi:10.1523/JNEUROSCI.4520-04.2005).
    • (2005) Journal of Neuroscience , vol.25 , pp. 4706-4718
    • Wang, J.M.1    Johnston, P.B.2    Ball, B.G.3    Brinton, R.D.4
  • 224
    • 68949202516 scopus 로고    scopus 로고
    • Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders
    • Wang M, Wey S, Zhang Y, Ye R & Lee AS 2009 Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders. Antioxidants & Redox Signaling 11 2307-2316. (doi:10.1089/ars.2009.2485).
    • (2009) Antioxidants & Redox Signaling , vol.11 , pp. 2307-2316
    • Wang, M.1    Wey, S.2    Zhang, Y.3    Ye, R.4    Lee, A.S.5
  • 225
    • 0029118238 scopus 로고
    • Cytochrome P450 in the brain: neuroendocrine functions
    • Warner M & Gustafsson JA 1995 Cytochrome P450 in the brain: neuroendocrine functions. Frontiers in Neuroendocrinology 16 224-236. (doi:10.1006/frne.1995.1008).
    • (1995) Frontiers in Neuroendocrinology , vol.16 , pp. 224-236
    • Warner, M.1    Gustafsson, J.A.2
  • 226
    • 0021330944 scopus 로고
    • Electrophysiological and pharmacological actions of the convulsant benzodiazepine Ro 5-4864
    • Weissman BA, Cott J, Hommer D, Paul S & Skolnick P 1984 Electrophysiological and pharmacological actions of the convulsant benzodiazepine Ro 5-4864. European Journal of Pharmacology 97 257-263. (doi:10.1016/0014-2999(84)90457-6).
    • (1984) European Journal of Pharmacology , vol.97 , pp. 257-263
    • Weissman, B.A.1    Cott, J.2    Hommer, D.3    Paul, S.4    Skolnick, P.5
  • 229
    • 0035118243 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein and peripheral-type benzodiazepine receptor associate at the mitochondrial membrane
    • West LA, Horvat RD, Roess DA, Barisas BG, Juengel JL & Niswender GD 2001 Steroidogenic acute regulatory protein and peripheral-type benzodiazepine receptor associate at the mitochondrial membrane. Endocrinology 142 502-505. (doi:10.1210/endo.142.1.8052).
    • (2001) Endocrinology , vol.142 , pp. 502-505
    • West, L.A.1    Horvat, R.D.2    Roess, D.A.3    Barisas, B.G.4    Juengel, J.L.5    Niswender, G.D.6
  • 230
    • 84862908844 scopus 로고    scopus 로고
    • Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling
    • Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, Bhojwani D, Carroll WL & Lee AS 2012 Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling. Blood 119 817-825. (doi:10.1182/blood-2011-06-357384).
    • (2012) Blood , vol.119 , pp. 817-825
    • Wey, S.1    Luo, B.2    Tseng, C.C.3    Ni, M.4    Zhou, H.5    Fu, Y.6    Bhojwani, D.7    Carroll, W.L.8    Lee, A.S.9
  • 231
    • 77952530199 scopus 로고    scopus 로고
    • Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
    • Wisniewska M, Karlberg T, Lehtio L, Johansson I, Kotenyova T, Moche M & Schuler H 2010 Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78. PLoS ONE 5 e8625. (doi:10.1371/journal.pone.0008625).
    • (2010) PLoS ONE , vol.5
    • Wisniewska, M.1    Karlberg, T.2    Lehtio, L.3    Johansson, I.4    Kotenyova, T.5    Moche, M.6    Schuler, H.7
  • 233
    • 77951646609 scopus 로고    scopus 로고
    • 4'-Chlorodiazepam, a translocator protein (18 kDa) antagonist, improves cardiac functional recovery during postischemia reperfusion in rats
    • Xiao J, Liang D, Zhang H, Liu Y, Li F & Chen YH 2010 4'-Chlorodiazepam, a translocator protein (18 kDa) antagonist, improves cardiac functional recovery during postischemia reperfusion in rats. Experimental Biology and Medicine 235 478-486. (doi:10.1258/ebm.2009.009291).
    • (2010) Experimental Biology and Medicine , vol.235 , pp. 478-486
    • Xiao, J.1    Liang, D.2    Zhang, H.3    Liu, Y.4    Li, F.5    Chen, Y.H.6
  • 234
    • 84904231986 scopus 로고    scopus 로고
    • Interactions of caveolin-1 scaffolding and intramembrane regions containing a CRAC motif with cholesterol in lipid bilayers
    • Yang G, Xu H, Li Z & Li F 2014 Interactions of caveolin-1 scaffolding and intramembrane regions containing a CRAC motif with cholesterol in lipid bilayers. Biochimica et Biophysica Acta 1838 2588-2599. (doi:10.1016/j.bbamem.2014.06.018).
    • (2014) Biochimica et Biophysica Acta , vol.1838 , pp. 2588-2599
    • Yang, G.1    Xu, H.2    Li, Z.3    Li, F.4
  • 235
    • 77649178742 scopus 로고    scopus 로고
    • Progesterone treatment reduces disease severity and increases IL-10 in experimental autoimmune encephalomyelitis
    • Yates MA, Li Y, Chlebeck P, Proctor T, Vandenbark AA & Offner H 2010 Progesterone treatment reduces disease severity and increases IL-10 in experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 220 136-139. (doi:10.1016/j.jneuroim.2010.01.013).
    • (2010) Journal of Neuroimmunology , vol.220 , pp. 136-139
    • Yates, M.A.1    Li, Y.2    Chlebeck, P.3    Proctor, T.4    Vandenbark, A.A.5    Offner, H.6
  • 236
    • 0030977125 scopus 로고    scopus 로고
    • A mammalian mitochondrial drug receptor functions as a bacterial "oxygen" sensor
    • Yeliseev AA, Krueger KE & Kaplan S 1997 A mammalian mitochondrial drug receptor functions as a bacterial "oxygen" sensor. PNAS 94 5101-5106. (doi:10.1073/pnas.94.10.5101).
    • (1997) PNAS , vol.94 , pp. 5101-5106
    • Yeliseev, A.A.1    Krueger, K.E.2    Kaplan, S.3
  • 237
    • 77952671004 scopus 로고    scopus 로고
    • Progesterone attenuates neurological behavioral deficits of experimental autoimmune encephalomyelitis through remyelination with nucleus-sublocalized Olig1 protein
    • Yu HJ, Fei J, Chen XS, Cai QY, Liu HL, Liu GD & Yao ZX 2010 Progesterone attenuates neurological behavioral deficits of experimental autoimmune encephalomyelitis through remyelination with nucleus-sublocalized Olig1 protein. Neuroscience Letters 476 42-45. (doi:10.1016/j.neulet.2010.03.079).
    • (2010) Neuroscience Letters , vol.476 , pp. 42-45
    • Yu, H.J.1    Fei, J.2    Chen, X.S.3    Cai, Q.Y.4    Liu, H.L.5    Liu, G.D.6    Yao, Z.X.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.