2-Phenyl-imidazo[1,2-alpyridine derivatives as ligands for peripheral benzodiazepine receptors: Stimulation of neurosteroid synthesis and anticonflict action in rats

British Journal of Pharmacology

Volumn 127, Issue 1, 1999, Pages 177-187

  Serra, Mariangela ^a   Madau, Paola ^a   Chessa, Maria Francesca ^a   Caddeo, Monica ^a   Sanna, Enrico ^a   Trapani, Giuseppe ^b   Franco, Massimo ^b   Liso, Gaetano ^b   Purdy, Robert H ^d   Barbaccia, Maria Luisa ^c   Biggio, Giovanni ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

6,8 Disubstituted aminopyridines; Anxiety; Peripheral benzodiazepine receptor; Steroidogenesis

Indexed keywords

2 PHENYLIMIDAZO[1,2A]PYRIDINE DERIVATIVE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; 6 BROMO N,N DIISOPROPYL 8 METHYL 2 PHENYLIMIDAZO[1,2 A]PYRIDINE 3 CARBOXAMIDE; 6,8 DICHLORO 2 (4 CHLOROPHENYL) N,N DIISOPROPYLIMIDAZO[1,2 A]PYRIDINE 3 CARBOXAMIDE; 6,8 DICHLORO N,N DIISOPROPYL 2 PHENYLIMIDAZO[1,2 A]PYRIDINE 3 CARBOXAMIDE; BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; CHLORIDE ION; CORTICOSTERONE DERIVATIVE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; FLUNITRAZEPAM; MUSCARINIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROSTEROID; OPIATE RECEPTOR; PREGNENOLONE; PROGESTERONE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ADRENALECTOMY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN MEMBRANE; CHLORIDE CURRENT; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; OOCYTE; ORCHIECTOMY; OVARY; PRIORITY JOURNAL; RADIOASSAY; RAT; STEROID BLOOD LEVEL; STEROIDOGENESIS; XENOPUS;

ADRENALECTOMY; ANIMALS; BRAIN; CONFLICT (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IMIDAZOLES; INJECTIONS, INTRAPERITONEAL; LIGANDS; MALE; OLIGODENDROGLIA; OOCYTES; ORCHIECTOMY; PERIPHERAL NERVOUS SYSTEM; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; STEROIDS; STIMULATION, CHEMICAL; XENOPUS LAEVIS;

EID: 0032908756     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702530     Document Type: Article

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