The anxiolytic etifoxine activates the peripheral benzodiazepine receptor and increases the neurosteroid levels in rat brain

Pharmacology Biochemistry and Behavior

Volumn 82, Issue 4, 2005, Pages 712-720

  Verleye, Marc ^a   Akwa, Yvette ^b   Liere, Philippe ^b   Ladurelle, Nathalie ^b   Pianos, Antoine ^b   Eychenne, Bernard ^b   Schumacher, Michael ^b   Gillardin, Jean Marie ^a  

^a Service de Pharmacologie   (France)

^b INSERM   (France)

Author keywords

Adrenalectomized castrated rats; Allopregnanolone; Anxiety; Etifoxine; Finasteride; Neurosteroids; Peripheral benzodiazepine receptor; Plasma and brain etifoxine levels

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 5ALPHA PREGNANE 3,20 DIONE; ANXIOLYTIC AGENT; BENZODIAZEPINE RECEPTOR; BENZOXAZINE DERIVATIVE; ETIFOXINE; FINASTERIDE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROSTEROID; PREGNENOLONE; PROGESTERONE; UNCLASSIFIED DRUG;

ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CASTRATION; CONFLICT; CONTROLLED STUDY; FOREBRAIN; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STEROIDOGENESIS; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; BRAIN; ISOQUINOLINES; MALE; OXAZINES; PREGNANOLONE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, GABA-A; STEROIDS;

ANIMALIA;

EID: 31844436767     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2005.11.013     Document Type: Article

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