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Volumn 157, Issue 3, 2016, Pages 1110-1121

Translocator protein (TSPO) affects mitochondrial fatty acid oxidation in steroidogenic cells

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; FATTY ACID; GLUCOSE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; 4 AMINOBUTYRIC ACID RECEPTOR; BZRP PROTEIN, MOUSE; ION CHANNEL; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 2, MOUSE; MESSENGER RNA; MITOCHONDRIAL PROTEIN; PROGESTERONE; VDAC1 PROTEIN, MOUSE; VOLTAGE DEPENDENT ANION CHANNEL 1;

EID: 84960532896     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1795     Document Type: Article
Times cited : (78)

References (72)
  • 1
    • 0000114680 scopus 로고
    • Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H) diazepam binding
    • Braestrup C, Squires RF. Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H) diazepam binding. Proc Natl Acad Sci USA. 1977;74:3805-3809.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 3805-3809
    • Braestrup, C.1    Squires, R.F.2
  • 2
    • 0029096540 scopus 로고
    • A sensory transducer homologous to the mammalian peripheral-type benzodiazepine receptor regulates photosynthetic membrane complex formation in Rhodobacter sphaeroides 2.4.1
    • Yeliseev AA, Kaplan S. A sensory transducer homologous to the mammalian peripheral-type benzodiazepine receptor regulates photosynthetic membrane complex formation in Rhodobacter sphaeroides 2.4.1. J Biol Chem. 1995;270:21167-21175.
    • (1995) J Biol Chem. , vol.270 , pp. 21167-21175
    • Yeliseev, A.A.1    Kaplan, S.2
  • 3
    • 0032707529 scopus 로고    scopus 로고
    • Enigma of the peripheral benzodiazepine receptor
    • Gavish M, Bachman I, Shoukrun R, et al. Enigma of the peripheral benzodiazepine receptor. Pharmacol Rev. 1999;51:629-650.
    • (1999) Pharmacol Rev. , vol.51 , pp. 629-650
    • Gavish, M.1    Bachman, I.2    Shoukrun, R.3
  • 4
    • 84860264736 scopus 로고    scopus 로고
    • The 18 kDa translocator protein (TSPO): A new perspective in mitochondrial biology
    • Gatliff J, Campanella M. The 18 kDa translocator protein (TSPO): a new perspective in mitochondrial biology. Curr Mol Med. 2012;12:356-368.
    • (2012) Curr Mol Med. , vol.12 , pp. 356-368
    • Gatliff, J.1    Campanella, M.2
  • 5
    • 0031031675 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptorincholesterol transport and steroidogenesis
    • Papadopoulos V, Amri H, Boujrad N, et al. Peripheral benzodiazepine receptorincholesterol transport and steroidogenesis. Steroids. 1997;62:21-28.
    • (1997) Steroids. , vol.62 , pp. 21-28
    • Papadopoulos, V.1    Amri, H.2    Boujrad, N.3
  • 7
    • 0022574416 scopus 로고
    • The peripheraltype benzodiazepine receptor. Localization to the mitochondrial outer membrane
    • Anholt RR, Pedersen PL, De Souza EB, Snyder SH. The peripheraltype benzodiazepine receptor. Localization to the mitochondrial outer membrane. J Biol Chem. 1986;261:576-583.
    • (1986) J Biol Chem. , vol.261 , pp. 576-583
    • Anholt, R.R.1    Pedersen, P.L.2    De Souza, E.B.3    Snyder, S.H.4
  • 8
    • 84891379545 scopus 로고    scopus 로고
    • Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis
    • Morohaku K, Pelton SH, Daugherty DJ, Butler WR, Deng W, Selvaraj V. Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis. Endocrinology. 2014;155:89-97.
    • (2014) Endocrinology , vol.155 , pp. 89-97
    • Morohaku, K.1    Pelton, S.H.2    Daugherty, D.J.3    Butler, W.R.4    Deng, W.5    Selvaraj, V.6
  • 9
    • 84907293074 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis
    • Tu LN, Morohaku K, Manna PR, et al. Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis. J Biol Chem. 2014;289:27444-27454.
    • (2014) J Biol Chem. , vol.289 , pp. 27444-27454
    • Tu, L.N.1    Morohaku, K.2    Manna, P.R.3
  • 10
    • 84923241444 scopus 로고    scopus 로고
    • Positron emission tomography and functional characterization of a complete PBR/TSPO knockout
    • Banati RB, Middleton RJ, Chan R, et al. Positron emission tomography and functional characterization of a complete PBR/TSPO knockout. Nat Commun. 2014;5:5452.
    • (2014) Nat Commun. , vol.5 , pp. 5452
    • Banati, R.B.1    Middleton, R.J.2    Chan, R.3
  • 11
    • 84923870787 scopus 로고    scopus 로고
    • PK11195 effect on steroidogenesis is not mediated through the translocator protein (TSPO)
    • Tu LN, Zhao AH, Stocco DM, Selvaraj V. PK11195 effect on steroidogenesis is not mediated through the translocator protein (TSPO). Endocrinology. 2015:156:1033-1039.
    • (2015) Endocrinology , vol.156 , pp. 1033-1039
    • Tu, L.N.1    Zhao, A.H.2    Stocco, D.M.3    Selvaraj, V.4
  • 12
    • 84926316945 scopus 로고    scopus 로고
    • Minireview: Translocator protein (TSPO) and steroidogenesis: A reappraisal
    • Selvaraj V, Stocco DM, Tu LN. Minireview: translocator protein (TSPO) and steroidogenesis: a reappraisal. Mol Endocrinol. 2015;29:490-501.
    • (2015) Mol Endocrinol. , vol.29 , pp. 490-501
    • Selvaraj, V.1    Stocco, D.M.2    Tu, L.N.3
  • 13
    • 84937524245 scopus 로고    scopus 로고
    • The changing landscape in translocator protein (TSPO) function
    • Selvaraj V, Stocco DM. The changing landscape in translocator protein (TSPO) function. Trends EndocrinolMetab. 2015;26:341-348.
    • (2015) Trends EndocrinolMetab. , vol.26 , pp. 341-348
    • Selvaraj, V.1    Stocco, D.M.2
  • 14
    • 84931274608 scopus 로고    scopus 로고
    • Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation
    • Fan J, Campioli E, Midzak A, Culty M, Papadopoulos V. Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation. Proc Natl Acad Sci USA. 2015;112:7261-7266.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 7261-7266
    • Fan, J.1    Campioli, E.2    Midzak, A.3    Culty, M.4    Papadopoulos, V.5
  • 15
    • 0021944108 scopus 로고
    • Peripheral-type benzodiazepine receptors in endocrine organs: Autoradiographic localization in rat pituitary, adrenal, and testis
    • De Souza EB, Anholt RR, Murphy KM, Snyder SH, Kuhar MJ. Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis. Endocrinology. 1985;116:567-573.
    • (1985) Endocrinology , vol.116 , pp. 567-573
    • De Souza, E.B.1    Anholt, R.R.2    Murphy, K.M.3    Snyder, S.H.4    Kuhar, M.J.5
  • 17
    • 84883540434 scopus 로고    scopus 로고
    • Developmental expression of translocator protein/peripheral benzodiazepine receptor in reproductive tissues
    • Morohaku K, Phuong NS, Selvaraj V. Developmental expression of translocator protein/peripheral benzodiazepine receptor in reproductive tissues. PLoS One. 2013;8:e74509.
    • (2013) PLoS One , vol.8 , pp. e74509
    • Morohaku, K.1    Phuong, N.S.2    Selvaraj, V.3
  • 18
    • 0024590270 scopus 로고
    • Effects of peripheral benzodiazepines upon the O2 consumption of neuroblastoma cells
    • Larcher JC, Vayssiere JL, Le Marquer FJ, et al. Effects of peripheral benzodiazepines upon the O2 consumption of neuroblastoma cells. Eur J Pharmacol. 1989;161:197-202.
    • (1989) Eur J Pharmacol. , vol.161 , pp. 197-202
    • Larcher, J.C.1    Vayssiere, J.L.2    Le Marquer, F.J.3
  • 19
    • 0024497217 scopus 로고
    • Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control
    • Hirsch JD, Beyer CF, Malkowitz L, Beer B, Blume AJ. Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control. Mol Pharmacol. 1989;35:157-163.
    • (1989) Mol Pharmacol. , vol.35 , pp. 157-163
    • Hirsch, J.D.1    Beyer, C.F.2    Malkowitz, L.3    Beer, B.4    Blume, A.J.5
  • 20
    • 19744378270 scopus 로고    scopus 로고
    • Mechanisms of mitochondrial apoptosis induced by peripheral benzodiazepine receptor ligands in human colorectal cancer cells
    • Maaser K, Sutter AP, Scherübl H. Mechanisms of mitochondrial apoptosis induced by peripheral benzodiazepine receptor ligands in human colorectal cancer cells. Biochem Biophys Res Commun. 2005;332:646-652.
    • (2005) Biochem Biophys Res Commun. , vol.332 , pp. 646-652
    • Maaser, K.1    Sutter, A.P.2    Scherübl, H.3
  • 21
    • 28244459490 scopus 로고    scopus 로고
    • Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells
    • Furre IE, Shahzidi S, Luksiene Z, et al. Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells. Cancer Res. 2005;65:11051-11060.
    • (2005) Cancer Res. , vol.65 , pp. 11051-11060
    • Furre, I.E.1    Shahzidi, S.2    Luksiene, Z.3
  • 22
    • 33646380357 scopus 로고    scopus 로고
    • Mitochondrial ligand inhibits store-operated calcium influx and COX-2 production in human microglia
    • Hong SH, Choi HB, Kim SU, McLarnon JG. Mitochondrial ligand inhibits store-operated calcium influx and COX-2 production in human microglia. J Neurosci Res. 2006;83:1293-1298.
    • (2006) J Neurosci Res. , vol.83 , pp. 1293-1298
    • Hong, S.H.1    Choi, H.B.2    Kim, S.U.3    McLarnon, J.G.4
  • 23
    • 55949098674 scopus 로고    scopus 로고
    • Modulation of intracellular Ca2+ signalling in HeLa cells by the apoptotic cell death enhancer PK11195
    • Campanella M, Szabadkai G, Rizzuto R. Modulation of intracellular Ca2+ signalling in HeLa cells by the apoptotic cell death enhancer PK11195. Biochem Pharmacol. 2008;76:1628-1636.
    • (2008) Biochem Pharmacol. , vol.76 , pp. 1628-1636
    • Campanella, M.1    Szabadkai, G.2    Rizzuto, R.3
  • 24
    • 0035906835 scopus 로고    scopus 로고
    • Bcl-2 resistant mitochondrial toxicity mediated by the isoquinoline carboxamide PK11195 involves de novo generation of reactive oxygen species
    • Fennell DA, Corbo M, Pallaska A, Cotter FE. Bcl-2 resistant mitochondrial toxicity mediated by the isoquinoline carboxamide PK11195 involves de novo generation of reactive oxygen species. Br J Cancer. 2001;84:1397-1404.
    • (2001) Br J Cancer , vol.84 , pp. 1397-1404
    • Fennell, D.A.1    Corbo, M.2    Pallaska, A.3    Cotter, F.E.4
  • 25
    • 84860271665 scopus 로고    scopus 로고
    • The 18 kDa mitochondrial translocator protein (TSPO) prevents accumulation of protoporphyrin IX. Involvement of reactive oxygen species (ROS)
    • Zeno S, Veenman L, Katz Y, Bode J, Gavish M, Zaaroor M. The 18 kDa mitochondrial translocator protein (TSPO) prevents accumulation of protoporphyrin IX. Involvement of reactive oxygen species (ROS). Curr Mol Med. 2012;12:494-501.
    • (2012) Curr Mol Med. , vol.12 , pp. 494-501
    • Zeno, S.1    Veenman, L.2    Katz, Y.3    Bode, J.4    Gavish, M.5    Zaaroor, M.6
  • 26
    • 84860312483 scopus 로고    scopus 로고
    • Is there any correlation between binding and functional effects at the translocator protein (TSPO) (18 kDa) ?
    • Scarf AM, Auman KM, Kassiou M. Is there any correlation between binding and functional effects at the translocator protein (TSPO) (18 kDa) ? Curr Mol Med. 2012;12:387-397.
    • (2012) Curr Mol Med. , vol.12 , pp. 387-397
    • Scarf, A.M.1    Auman, K.M.2    Kassiou, M.3
  • 27
    • 47949111469 scopus 로고    scopus 로고
    • The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor
    • Li L, Chen T, Stanton JD, Sueyoshi T, Negishi M, Wang H. The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor. Mol Pharmacol. 2008;74:443-453.
    • (2008) Mol Pharmacol. , vol.74 , pp. 443-453
    • Li, L.1    Chen, T.2    Stanton, J.D.3    Sueyoshi, T.4    Negishi, M.5    Wang, H.6
  • 28
    • 84860303350 scopus 로고    scopus 로고
    • PK11195 inhibits mitophagy targeting the F1Fo-ATPsynthase in Bcl-2 knockdown cells
    • Seneviratne MS, Faccenda D, De Biase V, Campanella M. PK11195 inhibits mitophagy targeting the F1Fo-ATPsynthase in Bcl-2 knockdown cells. Curr Mol Med. 2012;12:476-482.
    • (2012) Curr Mol Med. , vol.12 , pp. 476-482
    • Seneviratne, M.S.1    Faccenda, D.2    De Biase, V.3    Campanella, M.4
  • 29
    • 84892410771 scopus 로고    scopus 로고
    • Investigating the interactions of the 18kDa translocator protein and its ligand PK11195 in planar lipid bilayers
    • Hatty CR, Le Brun AP, Lake V, et al. Investigating the interactions of the 18kDa translocator protein and its ligand PK11195 in planar lipid bilayers. Biochim Biophys Acta. 2014;1838:1019-1030.
    • (2014) Biochim Biophys Acta. , vol.1838 , pp. 1019-1030
    • Hatty, C.R.1    Le Brun, A.P.2    Lake, V.3
  • 31
    • 84901008605 scopus 로고    scopus 로고
    • Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (translocator protein of 18 kDa (TSPO))
    • Šileikyt J, Blachly-Dyson E, Sewell R, et al. Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (translocator protein of 18 kDa (TSPO)). J Biol Chem. 2014;289:13769-13781.
    • (2014) J Biol Chem. , vol.289 , pp. 13769-13781
    • Šileikyt, J.1    Blachly-Dyson, E.2    Sewell, R.3
  • 33
    • 0019364734 scopus 로고
    • Characterization of several clonal lines of cultured Leydig tumor cells: Gonadotropin receptors and steroidogenic responses
    • Ascoli M. Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses. Endocrinology. 1981;108:88-95.
    • (1981) Endocrinology , vol.108 , pp. 88-95
    • Ascoli, M.1
  • 34
    • 68449083213 scopus 로고    scopus 로고
    • A versatile viral system for expression and depletion of proteins in mammalian cells
    • Campeau E, Ruhl VE, Rodier F, et al. A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS One. 2009;4:e6529.
    • (2009) PLoS One , vol.4 , pp. e6529
    • Campeau, E.1    Ruhl, V.E.2    Rodier, F.3
  • 35
    • 75549089019 scopus 로고    scopus 로고
    • PrimerBank: A resource of human and mouse PCR primer pairs for gene expression detection and quantification
    • Spandidos A, Wang X, Wang H, Seed B. PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification. Nucleic Acids Res. 2010;38:D792-D799.
    • (2010) Nucleic Acids Res. , vol.38 , pp. D792-D799
    • Spandidos, A.1    Wang, X.2    Wang, H.3    Seed, B.4
  • 36
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-ΔΔC (T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-ΔΔC (T)) method. Methods. 2001;25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 37
    • 0021953954 scopus 로고
    • Peripheraltype benzodiazepine receptors: Autoradiographic localization in whole-body sections of neonatal rats
    • Anholt RR, De Souza EB, Oster-Granite ML, Snyder SH. Peripheraltype benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats. J Pharmacol Exp Ther. 1985;233:517-526.
    • (1985) J Pharmacol Exp Ther. , vol.233 , pp. 517-526
    • Anholt, R.R.1    De Souza, E.B.2    Oster-Granite, M.L.3    Snyder, S.H.4
  • 38
    • 80051824901 scopus 로고    scopus 로고
    • Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice
    • Leduc MS, Hageman RS, Verdugo RA, et al. Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice. J Lipid Res. 2011;52:1672-1682.
    • (2011) J Lipid Res. , vol.52 , pp. 1672-1682
    • Leduc, M.S.1    Hageman, R.S.2    Verdugo, R.A.3
  • 39
    • 24344509286 scopus 로고    scopus 로고
    • Differential expression of the peripheral benzodiazepine receptor and gremlin during adipogenesis
    • Wade FM, Wakade C, Mahesh VB, Brann DW. Differential expression of the peripheral benzodiazepine receptor and gremlin during adipogenesis. Obes Res. 2005;13:818-822.
    • (2005) Obes Res. , vol.13 , pp. 818-822
    • Wade, F.M.1    Wakade, C.2    Mahesh, V.B.3    Brann, D.W.4
  • 40
    • 9144231787 scopus 로고    scopus 로고
    • Effects of peripheral benzodiazepine receptor ligands on proliferation and differentiation of human mesenchymal stem cells
    • Lee DH, Kang SK, Lee RH, et al. Effects of peripheral benzodiazepine receptor ligands on proliferation and differentiation of human mesenchymal stem cells. J Cell Physiol. 2004;198:91-99.
    • (2004) J Cell Physiol. , vol.198 , pp. 91-99
    • Lee, D.H.1    Kang, S.K.2    Lee, R.H.3
  • 41
    • 84894170581 scopus 로고    scopus 로고
    • Translocator protein 18 kDa (TSPO) is regulated in white and brown adipose tissue by obesity
    • Thompson MM, Manning HC, Ellacott KL. Translocator protein 18 kDa (TSPO) is regulated in white and brown adipose tissue by obesity. PLoS One. 2013;8:e79980.
    • (2013) PLoS One , vol.8 , pp. e79980
    • Thompson, M.M.1    Manning, H.C.2    Ellacott, K.L.3
  • 42
    • 77049124222 scopus 로고    scopus 로고
    • Chronic high fat, high cholesterol supplementation decreases 18 kDa Translocator Protein binding capacity in association with increased oxidative stress in rat liver and aorta
    • Dimitrova-Shumkovska J, Veenman L, Ristoski T, Leschiner S, Gavish M. Chronic high fat, high cholesterol supplementation decreases 18 kDa Translocator Protein binding capacity in association with increased oxidative stress in rat liver and aorta. Food Chem Toxicol. 2010;48:910-921.
    • (2010) Food Chem Toxicol. , vol.48 , pp. 910-921
    • Dimitrova-Shumkovska, J.1    Veenman, L.2    Ristoski, T.3    Leschiner, S.4    Gavish, M.5
  • 43
    • 33745222339 scopus 로고    scopus 로고
    • Defining high-fatdiet rat models: Metabolic and molecular effects of different fat types
    • Buettner R, Parhofer KG, Woenckhaus M, et al. Defining high-fatdiet rat models: metabolic and molecular effects of different fat types. J Mol Endocrinol. 2006;36:485-501.
    • (2006) J Mol Endocrinol. , vol.36 , pp. 485-501
    • Buettner, R.1    Parhofer, K.G.2    Woenckhaus, M.3
  • 44
    • 0001105243 scopus 로고
    • Long-chain carnitine acyltransferase and the role of acylcarnitine derivatives in the catalytic increase of fatty acid oxidation induced by carnitine
    • Fritz IB, Yue KT. Long-chain carnitine acyltransferase and the role of acylcarnitine derivatives in the catalytic increase of fatty acid oxidation induced by carnitine. J Lipid Res. 1963;4:279-288.
    • (1963) J Lipid Res. , vol.4 , pp. 279-288
    • Fritz, I.B.1    Yue, K.T.2
  • 45
    • 33745428666 scopus 로고    scopus 로고
    • Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation
    • Vats D, Mukundan L, Odegaard JI, et al. Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation. Cell Metab. 2006;4:13-24.
    • (2006) Cell Metab. , vol.4 , pp. 13-24
    • Vats, D.1    Mukundan, L.2    Odegaard, J.I.3
  • 46
    • 84860168205 scopus 로고    scopus 로고
    • Inhibition of fatty acid metabolism ameliorates disease activity in an animal model of multiple sclerosis
    • Shriver LP, Manchester M. Inhibition of fatty acid metabolism ameliorates disease activity in an animal model of multiple sclerosis. Sci Rep. 2011;1:79.
    • (2011) Sci Rep. , vol.1 , pp. 79
    • Shriver, L.P.1    Manchester, M.2
  • 47
    • 74949089659 scopus 로고    scopus 로고
    • Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
    • Samudio I, Harmancey R, Fiegl M, et al. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. J Clin Invest. 2010;120:142-156.
    • (2010) J Clin Invest. , vol.120 , pp. 142-156
    • Samudio, I.1    Harmancey, R.2    Fiegl, M.3
  • 48
    • 79955601028 scopus 로고    scopus 로고
    • Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
    • Pike LS, Smift AL, Croteau NJ, Ferrick DA, Wu M. Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells. Biochim Biophys Acta. 2011;1807:726-734.
    • (2011) Biochim Biophys Acta , vol.1807 , pp. 726-734
    • Pike, L.S.1    Smift, A.L.2    Croteau, N.J.3    Ferrick, D.A.4    Wu, M.5
  • 49
    • 84875465199 scopus 로고    scopus 로고
    • Cancer metabolism: Fatty acid oxidation in the limelight
    • Carracedo A, Cantley LC, Pandolfi PP. Cancer metabolism: fatty acid oxidation in the limelight. Nat Rev Cancer. 2013;13:227-232.
    • (2013) Nat Rev Cancer. , vol.13 , pp. 227-232
    • Carracedo, A.1    Cantley, L.C.2    Pandolfi, P.P.3
  • 50
    • 84955460175 scopus 로고    scopus 로고
    • Mitochondrial translocator protein (TSPO) function is not essential for heme biosynthesis
    • Zhao AH, Tu LN, Mukai C, et al. Mitochondrial translocator protein (TSPO) function is not essential for heme biosynthesis. J Biol Chem. doi: 10.1074/jbc. M115.686360.
    • J Biol Chem.
    • Zhao, A.H.1    Tu, L.N.2    Mukai, C.3
  • 51
    • 0029915241 scopus 로고    scopus 로고
    • Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage
    • Carayon P, Portier M, Dussossoy D, et al. Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage. Blood. 1996;87:3170-3178.
    • (1996) Blood , vol.87 , pp. 3170-3178
    • Carayon, P.1    Portier, M.2    Dussossoy, D.3
  • 52
    • 84886439847 scopus 로고    scopus 로고
    • Mitochondrial translocator protein (TSPO) ligands prevent doxorubicin-induced mechanical dysfunction and cell death in isolated cardiomyocytes
    • de Tassigny Ad, Assaly R, Schaller S, Pruss RM, Berdeaux A, Morin D. Mitochondrial translocator protein (TSPO) ligands prevent doxorubicin-induced mechanical dysfunction and cell death in isolated cardiomyocytes. Mitochondrion. 2013;13:688-697.
    • (2013) Mitochondrion , vol.13 , pp. 688-697
    • De Tassigny, Ad.1    Assaly, R.2    Schaller, S.3    Pruss, R.M.4    Berdeaux, A.5    Morin, D.6
  • 53
    • 52449115923 scopus 로고    scopus 로고
    • VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis
    • Veenman L, Shandalov Y, Gavish M. VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis. JBioenerg Biomembr. 2008;40:199-205.
    • (2008) JBioenerg Biomembr. , vol.40 , pp. 199-205
    • Veenman, L.1    Shandalov, Y.2    Gavish, M.3
  • 54
    • 84922177703 scopus 로고    scopus 로고
    • TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control
    • Gatliff J, East D, Crosby J, et al. TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control. Autophagy. 2014;10:2279-2296.
    • (2014) Autophagy , vol.10 , pp. 2279-2296
    • Gatliff, J.1    East, D.2    Crosby, J.3
  • 55
    • 84866278651 scopus 로고    scopus 로고
    • The expression of translocator protein in human thyroid cancer and its role in the response of thyroid cancer cells to oxidative stress
    • Klubo-Gwiezdzinska J, Jensen K, Bauer A, et al. The expression of translocator protein in human thyroid cancer and its role in the response of thyroid cancer cells to oxidative stress. J Endocrinol. 2012;214:207-216.
    • (2012) J Endocrinol. , vol.214 , pp. 207-216
    • Klubo-Gwiezdzinska, J.1    Jensen, K.2    Bauer, A.3
  • 56
    • 84864387242 scopus 로고    scopus 로고
    • Oxidation of fatty acids is the source of increased mitochondrial reactive oxygen species production in kidney cortical tubules in early diabetes
    • Rosca MG, Vazquez EJ, Chen Q, Kerner J, Kern TS, Hoppel CL. Oxidation of fatty acids is the source of increased mitochondrial reactive oxygen species production in kidney cortical tubules in early diabetes. Diabetes. 2012;61:2074-2083.
    • (2012) Diabetes , vol.61 , pp. 2074-2083
    • Rosca, M.G.1    Vazquez, E.J.2    Chen, Q.3    Kerner, J.4    Kern, T.S.5    Hoppel, C.L.6
  • 57
    • 84855794688 scopus 로고    scopus 로고
    • Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state
    • Schönfeld P, Wojtczak L. Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state. Biochim Biophys Acta. 2012;1817:410-418.
    • (2012) Biochim Biophys Acta , vol.1817 , pp. 410-418
    • Schönfeld, P.1    Wojtczak, L.2
  • 58
    • 49649122302 scopus 로고    scopus 로고
    • UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
    • Andrews ZB, Liu ZW, Walllingford N, et al. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature. 2008;454:846-851.
    • (2008) Nature , vol.454 , pp. 846-851
    • Andrews, Z.B.1    Liu, Z.W.2    Walllingford, N.3
  • 59
    • 77957304618 scopus 로고    scopus 로고
    • Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function
    • Pi J, Collins S. Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function. Diabetes Obes Metab. 2010;12(suppl 2):141-148.
    • (2010) Diabetes Obes Metab. , vol.12 , pp. 141-148
    • Pi, J.1    Collins, S.2
  • 60
    • 84892928725 scopus 로고    scopus 로고
    • UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation
    • Vozza A, Parisi G, De Leonardis F, et al. UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation. Proc Natl Acad Sci USA. 2014;111:960-965.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 960-965
    • Vozza, A.1    Parisi, G.2    De Leonardis, F.3
  • 61
    • 84903469647 scopus 로고    scopus 로고
    • Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity
    • Kukat A, Dogan SA, Edgar D, et al. Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. PLoS Genet. 2014;10:e1004385.
    • (2014) PLoS Genet , vol.10 , pp. e1004385
    • Kukat, A.1    Dogan, S.A.2    Edgar, D.3
  • 63
    • 0025300030 scopus 로고
    • Distribution and characterization of diazepam binding inhibitor (DBI) in peripheral tissues of rat
    • Bovolin P, Schlichting J, Miyata M, Ferrarese C, Guidotti A, Alho H. Distribution and characterization of diazepam binding inhibitor (DBI) in peripheral tissues of rat. Regul Pept. 1990;29:267-281.
    • (1990) Regul Pept. , vol.29 , pp. 267-281
    • Bovolin, P.1    Schlichting, J.2    Miyata, M.3    Ferrarese, C.4    Guidotti, A.5    Alho, H.6
  • 64
    • 0026051933 scopus 로고
    • Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors
    • Papadopoulos V, Berkovich A, Krueger KE, Costa E, Guidotti A. Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors. Endocrinology. 1991;129:1481-1488.
    • (1991) Endocrinology , vol.129 , pp. 1481-1488
    • Papadopoulos, V.1    Berkovich, A.2    Krueger, K.E.3    Costa, E.4    Guidotti, A.5
  • 65
    • 79952808760 scopus 로고    scopus 로고
    • Disruption of the acyl-CoA-binding protein gene delays hepatic adaptation to metabolic changes at weaning
    • Neess D, Bloksgaard M, Bek S, et al. Disruption of the acyl-CoA-binding protein gene delays hepatic adaptation to metabolic changes at weaning. J Biol Chem. 2011;286:3460-3472.
    • (2011) J Biol Chem. , vol.286 , pp. 3460-3472
    • Neess, D.1    Bloksgaard, M.2    Bek, S.3
  • 66
    • 33845736814 scopus 로고    scopus 로고
    • Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin
    • Lee L, De Bono CA, Campagna DR, Young DC, Moody DB, Fleming MD. Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin. J Invest Dermatol. 2007;127:16-23.
    • (2007) J Invest Dermatol. , vol.127 , pp. 16-23
    • Lee, L.1    De Bono, C.A.2    Campagna, D.R.3    Young, D.C.4    Moody, D.B.5    Fleming, M.D.6
  • 67
    • 0028018037 scopus 로고
    • Localization of diazepam-binding inhibitor and peripheral type benzodiazepine binding sites in the rat ovary
    • Toranzo D, Tong Y, Tonon MC, Vaudry H, Pelletier G. Localization of diazepam-binding inhibitor and peripheral type benzodiazepine binding sites in the rat ovary. Anat Embryol (Berl). 1994;190:383-388.
    • (1994) Anat Embryol (Berl) , vol.190 , pp. 383-388
    • Toranzo, D.1    Tong, Y.2    Tonon, M.C.3    Vaudry, H.4    Pelletier, G.5
  • 68
    • 0025876996 scopus 로고
    • Localization of peripheral benzodiazepine binding sites and diazepam-binding inhibitor (DBI) mRNA in mammary glands and dimethylbenz (a) antracene (DMBA)-induced mammary tumors in the rat
    • Tong Y, Rhéaume E, Simard J, Pelletier G. Localization of peripheral benzodiazepine binding sites and diazepam-binding inhibitor (DBI) mRNA in mammary glands and dimethylbenz (a) antracene (DMBA)-induced mammary tumors in the rat. Regul Pept. 1991;33:263-273.
    • (1991) Regul Pept. , vol.33 , pp. 263-273
    • Tong, Y.1    Rhéaume, E.2    Simard, J.3    Pelletier, G.4
  • 69
    • 0032508707 scopus 로고    scopus 로고
    • Inhibition of 3T3-L1 adipocyte differentiationbyexpressionofacyl-CoA-binding protein antisense RNA
    • Mandrup S, Sorensen RV, Helledie T, et al. Inhibition of 3T3-L1 adipocyte differentiationbyexpressionofacyl-CoA-binding protein antisense RNA. J Biol Chem. 1998;273:23897-23903.
    • (1998) J Biol Chem. , vol.273 , pp. 23897-23903
    • Mandrup, S.1    Sorensen, R.V.2    Helledie, T.3
  • 70
    • 0026591024 scopus 로고
    • Isolation of the mitochondrial benzodiazepine receptor: Association with the voltage-dependent anion channel and theadenine nucleotide carrier
    • McEnery MW, Snowman AM, Trifiletti RR, Snyder SH. Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and theadenine nucleotide carrier. Proc Natl Acad Sci USA. 1992;89:3170-3174.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3170-3174
    • McEnery, M.W.1    Snowman, A.M.2    Trifiletti, R.R.3    Snyder, S.H.4
  • 71
    • 79960402453 scopus 로고    scopus 로고
    • Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex
    • Lee K, Kerner J, Hoppel CL. Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex. J Biol Chem. 2011;286:25655-25662.
    • (2011) J Biol Chem. , vol.286 , pp. 25655-25662
    • Lee, K.1    Kerner, J.2    Hoppel, C.L.3
  • 72
    • 82755171864 scopus 로고    scopus 로고
    • An environment-dependent structural switch underlies the regulation of carnitine palmitoyltransferase 1A
    • Rao JN, Warren GZ, Estolt-Povedano S, Zammit VA, Ulmer TS. An environment-dependent structural switch underlies the regulation of carnitine palmitoyltransferase 1A. J Biol Chem. 2011;286:42545-42554.
    • (2011) J Biol Chem. , vol.286 , pp. 42545-42554
    • Rao, J.N.1    Warren, G.Z.2    Estolt-Povedano, S.3    Zammit, V.A.4    Ulmer, T.S.5


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