Cardioprotection by the TSPO ligand 4′-chlorodiazepam is associated with inhibition of mitochondrial accumulation of cholesterol at reperfusion

Cardiovascular Research

Volumn 98, Issue 3, 2013, Pages 420-427

  Paradis, Stéphanie ^a,b   Leoni, Valerio ^c   Caccia, Claudio ^c   Berdeaux, Alain ^a,b   Morin, Didier ^a,b  

^a INSERM U955   (France)

^b FACULTÉ DE MÉDECINE   (France)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

Cardioprotection; Cholesterol; Mitochondria; Oxysterols; Translocator protein

Indexed keywords

4' CHLORODIAZEPAM; 7 OXOCHOLESTEROL; 7ALPHA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; CARDIOVASCULAR AGENT; CHOLESTEROL; CHOLESTEROL 5ALPHA,6ALPHA OXIDE; CHOLESTEROL 5BETA,6BETA OXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRO 40303; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; EX VIVO STUDY; HEART PROTECTION; LIPID PEROXIDATION; MALE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION;

CARDIOPROTECTION; CHOLESTEROL; MITOCHONDRIA; OXYSTEROLS; TRANSLOCATOR PROTEIN;

ANIMALS; BENZODIAZEPINONES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CHOLESTEROL; CYTOPROTECTION; DISEASE MODELS, ANIMAL; LIGANDS; LIPID PEROXIDATION; MALE; MEMBRANE FLUIDITY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXIMES; PROTECTIVE AGENTS; RATS; RATS, WISTAR; RECEPTORS, GABA-A; SECOSTEROIDS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TIME FACTORS;

EID: 84877937811     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt079     Document Type: Article

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