Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: Synthesis, binding affinity, and in vivo studies

Journal of Medicinal Chemistry

Volumn 42, Issue 19, 1999, Pages 3934-3941

  Trapani, Giuseppe ^a   Franco, Massimo ^a   Latrofa, Andrea ^a   Ricciardi, Laura ^a   Carotti, Angelo ^a   Serra, Mariangela ^b   Sanna, Enrico ^b   Biggio, Giovanni ^b   Liso, Gaetano ^a  

^a UNIVERSITY OF BARI   (Italy)

^b Sezione di Neuroscienze   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

N,N DI N BUTYL (2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL)ACETAMIDE; N,N DI N PROPYL (2 PHENYL 6 METHOXYCARBONYLIMIDAZO[1,2 A]PYRIDIN 3 YL)ACETAMIDE; N,N DI N PROPYL [2 (4 CHLOROPHENYL) 8 CHLOROIMIDAZO[1,2 A]PYRIDIN 3 YL]ACETAMIDE; N,N DI N PROPYL [2 (4 CHLOROPHENYL) 8 METHYLIMIDAZO[1,2 A]PYRIDIN 3 YL]ACETAMIDE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; FEMALE; LIGAND BINDING; MALE; NONHUMAN; RAT;

ANIMALS; CLONING, MOLECULAR; DESOXYCORTICOSTERONE; FEMALE; HUMANS; IMIDAZOLES; ISOQUINOLINES; LIGANDS; MALE; OOCYTES; PREGNENOLONE; PROGESTERONE; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS;

EID: 0033598378     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991035g     Document Type: Article

References (30)

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