Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in animal models of post-traumatic stress disorder

International Journal of Neuropsychopharmacology

Volumn 29, Issue 4, 2014, Pages 1659-1669

  Zhang, Li Ming ^a   Qiu, Zhi Kun ^a,b   Zhao, Nan ^a   Chen, Hong Xia ^a   Liu, Yan Qin ^a   Xu, Jiang Ping ^b   Zhang, You Zhi ^a   Yang, Ri Fang ^a   Li, Yun Feng ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Allopregnanolone; neurosteroids; post traumatic stress disorder; translocator protein 18 kDa; YL IPA08

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ANXIOLYTIC AGENT; CARRIER PROTEIN; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROSTEROID; UNCLASSIFIED DRUG; [N ETHYL N (2 PYRIDINYLMETHYL) 2 (3,4 ICHLOROPHENYL) 7 METHYLIMIDAZO [1,2 A]PYRIDINE 3 ACETAMIDE HYDROCHLORIDE]; 4 AMINOBUTYRIC ACID RECEPTOR; BZRP PROTEIN, MOUSE; IMIDAZOLE DERIVATIVE; ISOQUINOLINE DERIVATIVE; N-ETHYL-N-(2-PYRIDINYLMETHYL)-2-(3,4-CHLOROPHENYL)-7-METHYLIMIDAZO(1,2-A)PYRIDINE-3-ACETAMIDE; PYRIDINE DERIVATIVE; SERTRALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; CLINICAL ASSESSMENT; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; DRUG POTENCY; DRUG SYNTHESIS; EXPLORATORY BEHAVIOR TEST; FEAR; FOOTSHOCK; LOCOMOTION; LONG TERM CARE; MALE; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; TRANQUILIZING ACTIVITY; ANALYSIS OF VARIANCE; ANIMAL; CATALEPSY; CHEMISTRY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; ELECTROSHOCK; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOTOR ACTIVITY; SPRAGUE DAWLEY RAT; STRESS DISORDERS, POST-TRAUMATIC;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-ANXIETY AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSHOCK; FREEZING REACTION, CATALEPTIC; IMIDAZOLES; ISOQUINOLINES; MALE; MICE; MICE, INBRED ICR; MOTOR ACTIVITY; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA; SERTRALINE; STRESS DISORDERS, POST-TRAUMATIC;

EID: 84930252571     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145714000479     Document Type: Article

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