Structure of the mitochondrial translocator protein in complex with a diagnostic ligand

Science

Volumn 343, Issue 6177, 2014, Pages 1363-1366

  Jaremko, Łukasz ^a,b   Jaremko, Mariusz ^a   Giller, Karin ^a   Becker, Stefan ^a   Zweckstetter, Markus ^a,b,c  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^c University Medical Center   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRANSLOCATOR PROTEIN; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID RECEPTOR; BZRP PROTEIN, MOUSE; CARRIER PROTEIN; CHOLESTEROL; ISOQUINOLINE DERIVATIVE; LIGAND; MICELLE; PROTEIN BINDING; RECOMBINANT PROTEIN;

LIGAND; MEMBRANE; MITOCHONDRIAL DNA; MOLECULAR ANALYSIS; PROTEIN;

ANXIETY DISORDER; ARTICLE; BRAIN INJURY; CHOLESTEROL TRANSPORT; DEUTERIUM HYDROGEN EXCHANGE; DRUG STRUCTURE; ELECTRON MICROSCOPY; ENCEPHALITIS; HYDROPHOBICITY; MICELLE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; STOICHIOMETRY; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; TRANSPORT AT THE CELLULAR LEVEL;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT; CHOLESTEROL; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ISOQUINOLINES; LIGANDS; MICE; MICELLES; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, GABA; RECOMBINANT PROTEINS;

EID: 84896998596     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1248725     Document Type: Article

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