Evidence for complex binding profiles and species differences at the translocator protein (TSPO) (18 kDa)

Current Molecular Medicine

Volumn 12, Issue 4, 2012, Pages 488-493

  Scarf, A M ^a   Luus, C ^a   da Pozzo, E ^b   Selleri, S ^c   Guarino, C ^c   Martini, C ^b   Ittner, L M ^a   Kassiou, M ^a,d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF PISA   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Binding cooperativity; Neuroprotection; Pyrrolobenzoxazepines; Radioligand binding; Structure activity relationships; Translocator protein (TSPO)

Indexed keywords

4' CHLORODIAZEPAM; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NITRIC OXIDE; OXAZEPINE DERIVATIVE; PREGNENOLONE; PROTEIN; PYRROLOBENZOXAZEPINE DERIVATIVE; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CELL PROLIFERATION; DRUG PROTEIN BINDING; GLIOMA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; MICROGLIA; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FUNCTION; RAT; SPECIES DIFFERENCE; STEROIDOGENESIS;

MURINAE; RATTUS;

EID: 84860267699     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/156652412800163460     Document Type: Article

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