Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway

Neuroscience

Volumn 210, Issue , 2012, Pages 442-450

  Ishrat, T ^a   Sayeed, I ^a   Atif, F ^a   Hua, F ^a   Stein, D G ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Growth factors; Ischemic stroke; Neuroprotection; Phosphoinositide 3 kinase akt pathway; Progesterone

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; P 0130; PHOSPHATIDYLINOSITOL 3 KINASE; PROGESTERONE; PROTEIN BAD; PROTEIN KINASE B; UNCLASSIFIED DRUG; VASCULOTROPIN; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG EFFECT; ELECTROCOAGULATION; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BRAIN; BRAIN INJURIES; BRAIN ISCHEMIA; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PROGESTERONE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84861186845     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.03.008     Document Type: Article

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