Enhancing neurosteroid synthesis - Relationship to the pharmacology of translocator protein (18 kDa) (TSPO) ligands and benzodiazepines

Pharmacopsychiatry

Volumn 48, Issue 2, 2015, Pages 72-77

  Wolf, L ^a   Bauer, A ^a   Melchner, D ^a   Hallof Buestrich, H ^a   Stoertebecker, P ^a   Haen, E ^a   Kreutz, M ^a   Sarubin, N ^a   Milenkovic, V M ^a   Wetzel, C H ^a   Rupprecht, R ^a   Nothdurfter, C ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

anxiolytic; benzodiazepines; neurosteroids; pregnenolone; TSPO ligands

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; EMAPUNIL; ETIFOXINE; MEMBRANE PROTEIN; NEUROSTEROID; PREGNENOLONE; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; N-BENZYL-N-ETHYL-2-(7,8-DIHYDRO-7-METHYL-8-OXO-2-PHENYL-9H-PURIN-9-YL)ACETAMIDE; OXAZINE DERIVATIVE; PURINE DERIVATIVE; TSPO PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; DRUG POTENCY; DRUG PROTEIN BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANQUILIZING ACTIVITY; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; RADIOASSAY;

ANIMALS; CELLS, CULTURED; DIAZEPAM; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; NEUROTRANSMITTER AGENTS; OXAZINES; PREGNENOLONE; PURINES; RADIOLIGAND ASSAY; RATS; RECEPTORS, GABA;

EID: 84924173806     PISSN: 01763679     EISSN: 14390795     Source Type: Journal    
DOI: 10.1055/s-0034-1398507     Document Type: Article

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