Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 23, 2015, Pages 7261-7266

  Fan, Jinjiang ^a,b   Campioli, Enrico ^a,b   Midzak, Andrew ^a,b   Culty, Martine ^a,b   Papadopoulos, Vassilios ^a,b  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Anti Mullerian hormone receptor type II; Knockout mice; Nuclear receptor subfamily 5 group A member 1; Steroidogenesis; Translocator protein

Indexed keywords

ADRENALIN; ANTI MULLERIAN HORMONE TYPE 2 RECEPTOR; CHOLESTEROL; CHORIONIC GONADOTROPIN; CORTICOSTERONE; CORTICOTROPIN; FAT DROPLET; MEMBRANE PROTEIN; PROTEIN CYPA11A1; PROTEIN MC2R; PROTEIN SCARB1; PROTEIN STARD1; TESTOSTERONE; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID RECEPTOR; BZRP PROTEIN, MOUSE;

ADRENAL CORTEX; ADRENAL MEDULLA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE DELETION; GENE EXPRESSION; GENETIC MODEL; GENOTYPE; MALE; MORULA; MOUSE; NONHUMAN; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROTEIN FUNCTION; SOMATIC CELL; STEROIDOGENESIS; TARGET CELL; ZYGOTE; ANIMAL; BIOSYNTHESIS; BRAIN; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; GONAD; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

MUS;

ANIMALS; BRAIN; CORTICOSTERONE; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; GONADS; MALE; MICE; MICE, KNOCKOUT; RECEPTORS, GABA; STRESS, PHYSIOLOGICAL; TESTOSTERONE;

EID: 84931274608     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1502670112     Document Type: Article

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