-
1
-
-
84859910283
-
Mitochondria in neurodegeneration
-
E. Lezi, and R.H. Swerdlow Mitochondria in neurodegeneration Adv. Exp. Med. Biol. 942 2012 269 286
-
(2012)
Adv. Exp. Med. Biol.
, vol.942
, pp. 269-286
-
-
Lezi, E.1
Swerdlow, R.H.2
-
2
-
-
56549086013
-
Review: Mitochondria and disease progression in multiple sclerosis
-
D. Mahad, H. Lassmann, and D. Turnbull Review: mitochondria and disease progression in multiple sclerosis Neuropathol. Appl. Neurobiol. 34 2008 577 589
-
(2008)
Neuropathol. Appl. Neurobiol.
, vol.34
, pp. 577-589
-
-
Mahad, D.1
Lassmann, H.2
Turnbull, D.3
-
3
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
J.W. Langston, P. Ballard, J.W. Tetrud, and I. Irwin Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis Science 219 1983 979 980
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
4
-
-
0035091767
-
The Parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): A technical review of its utility and safety
-
S. Przedborski, V. Jackson-Lewis, A.B. Naini, M. Jakowec, G. Petzinger, R. Miller, and M. Akram The Parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety J. Neurochem. 76 2001 1265 1274
-
(2001)
J. Neurochem.
, vol.76
, pp. 1265-1274
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Naini, A.B.3
Jakowec, M.4
Petzinger, G.5
Miller, R.6
Akram, M.7
-
5
-
-
0023281130
-
Inhibition of mitochondrial respiration by analogs of 4-phenylpyridine and 1-methyl-4-phenylpyridinium cation (MPP+), the neurotoxic metabolite of MPTP
-
C.L. Hoppel, D. Grinblatt, H.C. Kwok, P.K. Arora, M.P. Singh, and L.M. Sayre Inhibition of mitochondrial respiration by analogs of 4-phenylpyridine and 1-methyl-4-phenylpyridinium cation (MPP+), the neurotoxic metabolite of MPTP Biochem. Biophys. Res. Commun. 148 1987 684 693
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.148
, pp. 684-693
-
-
Hoppel, C.L.1
Grinblatt, D.2
Kwok, H.C.3
Arora, P.K.4
Singh, M.P.5
Sayre, L.M.6
-
6
-
-
0022516015
-
Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic Parkinsonism
-
R.R. Ramsay, J.I. Salach, J. Dadgar, and T.P. Singer Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic Parkinsonism Biochem. Biophys. Res. Commun. 135 1986 269 275
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.135
, pp. 269-275
-
-
Ramsay, R.R.1
Salach, J.I.2
Dadgar, J.3
Singer, T.P.4
-
7
-
-
0031001263
-
The content of intracellular mitochondrial DNA is decreased by 1-methyl-4-phenylpyridinium ion (MPP+)
-
K. Miyako, Y. Kai, T. Irie, K. Takeshige, and D. Kang The content of intracellular mitochondrial DNA is decreased by 1-methyl-4-phenylpyridinium ion (MPP+) J. Biol. Chem. 272 1997 9605 9608
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9605-9608
-
-
Miyako, K.1
Kai, Y.2
Irie, T.3
Takeshige, K.4
Kang, D.5
-
8
-
-
0033542739
-
MPP+ inhibits proliferation of PC12 cells by a p21(WAF1/Cip1)-dependent pathway and induces cell death in cells lacking p21(WAF1/Cip1)
-
F. Soldner, M. Weller, S. Haid, S. Beinroth, S.W. Miller, U. Wullner, R.E. Davis, J. Dichgans, T. Klockgether, and J.B. Schulz MPP+ inhibits proliferation of PC12 cells by a p21(WAF1/Cip1)-dependent pathway and induces cell death in cells lacking p21(WAF1/Cip1) Exp. Cell Res. 250 1999 75 85
-
(1999)
Exp. Cell Res.
, vol.250
, pp. 75-85
-
-
Soldner, F.1
Weller, M.2
Haid, S.3
Beinroth, S.4
Miller, S.W.5
Wullner, U.6
Davis, R.E.7
Dichgans, J.8
Klockgether, T.9
Schulz, J.B.10
-
9
-
-
0033934847
-
The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: The role of mitochondrial complex i and reactive oxygen species revisited
-
K. Nakamura, V.P. Bindokas, J.D. Marks, D.A. Wright, D.M. Frim, R.J. Miller, and U.J. Kang The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited Mol. Pharmacol. 58 2000 271 278
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 271-278
-
-
Nakamura, K.1
Bindokas, V.P.2
Marks, J.D.3
Wright, D.A.4
Frim, D.M.5
Miller, R.J.6
Kang, U.J.7
-
10
-
-
34948818775
-
Gene expression profiling of MPP+-treated MN9D cells: A mechanism of toxicity study
-
J. Wang, Z. Xu, H. Fang, H.M. Duhart, T.A. Patterson, and S.F. Ali Gene expression profiling of MPP+-treated MN9D cells: a mechanism of toxicity study Neurotoxicology 28 2007 979 987
-
(2007)
Neurotoxicology
, vol.28
, pp. 979-987
-
-
Wang, J.1
Xu, Z.2
Fang, H.3
Duhart, H.M.4
Patterson, T.A.5
Ali, S.F.6
-
11
-
-
54449089025
-
Mitochondrial complex i inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat
-
W.S. Choi, S.E. Kruse, R.D. Palmiter, and Z. Xia Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat Proc. Natl. Acad. Sci. U.S.A. 105 2008 15136 15141
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 15136-15141
-
-
Choi, W.S.1
Kruse, S.E.2
Palmiter, R.D.3
Xia, Z.4
-
12
-
-
0023111239
-
Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ion
-
Y. Mizuno, T. Saitoh, and N. Sone Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ion Biochem. Biophys. Res. Commun. 143 1987 971 976
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.143
, pp. 971-976
-
-
Mizuno, Y.1
Saitoh, T.2
Sone, N.3
-
13
-
-
0000340348
-
Parkinsonism-induced neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
-
J.A. Javitch, R.J. D'Amato, S.M. Strittmatter, and S.H. Snyder Parkinsonism-induced neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity Proc. Natl. Acad. Sci. U.S.A. 82 1985 2173 2177
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 2173-2177
-
-
Javitch, J.A.1
D'Amato, R.J.2
Strittmatter, S.M.3
Snyder, S.H.4
-
14
-
-
0027454020
-
Dopamine transporter expression confers cytotoxicity to low doses of the Parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium
-
C. Pifl, B. Giros, and M.G. Caron Dopamine transporter expression confers cytotoxicity to low doses of the Parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium J. Neurosci. 13 1993 4246 4253
-
(1993)
J. Neurosci.
, vol.13
, pp. 4246-4253
-
-
Pifl, C.1
Giros, B.2
Caron, M.G.3
-
15
-
-
0026713852
-
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter
-
Y. Liu, D. Peter, A. Roghani, S. Schuldiner, G.G. Prive, D. Eisenberg, N. Brecha, and R.H. Edwards A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter Cell 70 1992 539 551
-
(1992)
Cell
, vol.70
, pp. 539-551
-
-
Liu, Y.1
Peter, D.2
Roghani, A.3
Schuldiner, S.4
Prive, G.G.5
Eisenberg, D.6
Brecha, N.7
Edwards, R.H.8
-
16
-
-
0026756443
-
Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium
-
Y. Liu, A. Roghani, and R.H. Edwards Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium Proc. Natl. Acad. Sci. U.S.A. 89 1992 9074 9078
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 9074-9078
-
-
Liu, Y.1
Roghani, A.2
Edwards, R.H.3
-
17
-
-
0242270837
-
Inhibitory effects on mitochondrial complex i of semisynthetic mono-tetrahydrofuran acetogenin derivatives
-
J.R. Tormo, T. Gallardo, E. Peris, A. Bermejo, N. Cabedo, E. Estornell, M.C. Zafra-Polo, and D. Cortes Inhibitory effects on mitochondrial complex I of semisynthetic mono-tetrahydrofuran acetogenin derivatives Bioorg. Med. Chem. Lett. 13 2003 4101 4105
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 4101-4105
-
-
Tormo, J.R.1
Gallardo, T.2
Peris, E.3
Bermejo, A.4
Cabedo, N.5
Estornell, E.6
Zafra-Polo, M.C.7
Cortes, D.8
-
18
-
-
84866091599
-
Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death
-
S. Giordano, J. Lee, V.M. Darley-Usmar, and J. Zhang Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death PLoS One 7 2012 e44610
-
(2012)
PLoS One
, vol.7
, pp. e44610
-
-
Giordano, S.1
Lee, J.2
Darley-Usmar, V.M.3
Zhang, J.4
-
19
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
R. Betarbet, T.B. Sherer, G. MacKenzie, M. Garcia-Osuna, A.V. Panov, and J.T. Greenamyre Chronic systemic pesticide exposure reproduces features of Parkinson's disease Nat. Neurosci. 3 2000 1301 1306
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
20
-
-
64449085359
-
A highly reproducible rotenone model of Parkinson's disease
-
J.R. Cannon, V. Tapias, H.M. Na, A.S. Honick, R.E. Drolet, and J.T. Greenamyre A highly reproducible rotenone model of Parkinson's disease Neurobiol. Dis. 34 2009 279 290
-
(2009)
Neurobiol. Dis.
, vol.34
, pp. 279-290
-
-
Cannon, J.R.1
Tapias, V.2
Na, H.M.3
Honick, A.S.4
Drolet, R.E.5
Greenamyre, J.T.6
-
21
-
-
79955557808
-
Rotenone, paraquat, and Parkinson's disease
-
C.M. Tanner, F. Kamel, G.W. Ross, J.A. Hoppin, S.M. Goldman, M. Korell, C. Marras, G.S. Bhudhikanok, M. Kasten, A.R. Chade, K. Comyns, M.B. Richards, C. Meng, B. Priestley, H.H. Fernandez, F. Cambi, D.M. Umbach, A. Blair, D.P. Sandler, and J.W. Langston Rotenone, paraquat, and Parkinson's disease Environ. Health Perspect. 119 2011 866 872
-
(2011)
Environ. Health Perspect.
, vol.119
, pp. 866-872
-
-
Tanner, C.M.1
Kamel, F.2
Ross, G.W.3
Hoppin, J.A.4
Goldman, S.M.5
Korell, M.6
Marras, C.7
Bhudhikanok, G.S.8
Kasten, M.9
Chade, A.R.10
Comyns, K.11
Richards, M.B.12
Meng, C.13
Priestley, B.14
Fernandez, H.H.15
Cambi, F.16
Umbach, D.M.17
Blair, A.18
Sandler, D.P.19
Langston, J.W.20
more..
-
22
-
-
0035980445
-
Neurotoxicity of glutamate uptake inhibition in vivo: Correlation with succinate dehydrogenase activity and prevention by energy substrates
-
L. Massieu, P. Del Rio, and T. Montiel Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates Neuroscience 106 2001 669 677
-
(2001)
Neuroscience
, vol.106
, pp. 669-677
-
-
Massieu, L.1
Del Rio, P.2
Montiel, T.3
-
23
-
-
29144468251
-
3-Nitropropionic acid: A mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
-
E. Brouillet, C. Jacquard, N. Bizat, and D. Blum 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease J. Neurochem. 95 2005 1521 1540
-
(2005)
J. Neurochem.
, vol.95
, pp. 1521-1540
-
-
Brouillet, E.1
Jacquard, C.2
Bizat, N.3
Blum, D.4
-
24
-
-
0028836272
-
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate
-
J.G. Greene, and J.T. Greenamyre Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate J. Neurochem. 64 1995 430 436
-
(1995)
J. Neurochem.
, vol.64
, pp. 430-436
-
-
Greene, J.G.1
Greenamyre, J.T.2
-
25
-
-
79952368703
-
Loss of mitochondrial complex i activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model
-
W.S. Choi, R.D. Palmiter, and Z. Xia Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model J. Cell Biol. 192 2011 873 882
-
(2011)
J. Cell Biol.
, vol.192
, pp. 873-882
-
-
Choi, W.S.1
Palmiter, R.D.2
Xia, Z.3
-
26
-
-
84856976662
-
Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex i in dopamine neurons
-
F.H. Sterky, A.F. Hoffman, D. Milenkovic, B. Bao, A. Paganelli, D. Edgar, R. Wibom, C.R. Lupica, L. Olson, and N.G. Larsson Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons Hum. Mol. Genet. 21 2012 1078 1089
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 1078-1089
-
-
Sterky, F.H.1
Hoffman, A.F.2
Milenkovic, D.3
Bao, B.4
Paganelli, A.5
Edgar, D.6
Wibom, R.7
Lupica, C.R.8
Olson, L.9
Larsson, N.G.10
-
27
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
E.M. Valente, P.M. Abou-Sleiman, V. Caputo, M.M. Muqit, K. Harvey, S. Gispert, Z. Ali, D. Del Turco, A.R. Bentivoglio, D.G. Healy, A. Albanese, R. Nussbaum, R. Gonzalez-Maldonado, T. Deller, S. Salvi, P. Cortelli, W.P. Gilks, D.S. Latchman, R.J. Harvey, B. Dallapiccola, G. Auburger, and N.W. Wood Hereditary early-onset Parkinson's disease caused by mutations in PINK1 Science 304 2004 1158 1160
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
28
-
-
84927547966
-
Phenotypic variability of PINK1 expression: 12 years' clinical follow-up of two Italian families
-
L. Ricciardi, S. Petrucci, A. Guidubaldi, T. Ialongo, L. Serra, A. Ferraris, B. Spano, M. Bozzali, E.M. Valente, and A.R. Bentivoglio Phenotypic variability of PINK1 expression: 12 years' clinical follow-up of two Italian families Mov. Disord. 29 2014 1561 1566
-
(2014)
Mov. Disord.
, vol.29
, pp. 1561-1566
-
-
Ricciardi, L.1
Petrucci, S.2
Guidubaldi, A.3
Ialongo, T.4
Serra, L.5
Ferraris, A.6
Spano, B.7
Bozzali, M.8
Valente, E.M.9
Bentivoglio, A.R.10
-
29
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
D.P. Narendra, S.M. Jin, A. Tanaka, D.F. Suen, C.A. Gautier, J. Shen, M.R. Cookson, and R.J. Youle PINK1 is selectively stabilized on impaired mitochondria to activate Parkin PLoS Biol. 8 2010 e1000298
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000298
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
30
-
-
84898023373
-
PINK1 loss-of-function mutations affect mitochondrial complex i activity via NdufA10 ubiquinone uncoupling
-
V.A. Morais, D. Haddad, K. Craessaerts, P.J. De Bock, J. Swerts, S. Vilain, L. Aerts, L. Overbergh, A. Grunewald, P. Seibler, C. Klein, K. Gevaert, P. Verstreken, and B. De Strooper PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling Science 344 2014 203 207
-
(2014)
Science
, vol.344
, pp. 203-207
-
-
Morais, V.A.1
Haddad, D.2
Craessaerts, K.3
De Bock, P.J.4
Swerts, J.5
Vilain, S.6
Aerts, L.7
Overbergh, L.8
Grunewald, A.9
Seibler, P.10
Klein, C.11
Gevaert, K.12
Verstreken, P.13
De Strooper, B.14
-
32
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
-
X. Wang, D. Winter, G. Ashrafi, J. Schlehe, Y.L. Wong, D. Selkoe, S. Rice, J. Steen, M.J. LaVoie, and T.L. Schwarz PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility Cell 147 2011 893 906
-
(2011)
Cell
, vol.147
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
Ashrafi, G.3
Schlehe, J.4
Wong, Y.L.5
Selkoe, D.6
Rice, S.7
Steen, J.8
LaVoie, M.J.9
Schwarz, T.L.10
-
33
-
-
84894098297
-
Loss of PINK1 attenuates HIF-1alpha induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia
-
W. Lin, N.L. Wadlington, L. Chen, X. Zhuang, J.R. Brorson, and U.J. Kang Loss of PINK1 attenuates HIF-1alpha induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia J. Neurosci. 34 2014 3079 3089
-
(2014)
J. Neurosci.
, vol.34
, pp. 3079-3089
-
-
Lin, W.1
Wadlington, N.L.2
Chen, L.3
Zhuang, X.4
Brorson, J.R.5
Kang, U.J.6
-
34
-
-
39449098267
-
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP
-
M.E. Haque, K.J. Thomas, C. D'Souza, S. Callaghan, T. Kitada, R.S. Slack, P. Fraser, M.R. Cookson, A. Tandon, and D.S. Park Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP Proc. Natl. Acad. Sci. U.S.A. 105 2008 1716 1721
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 1716-1721
-
-
Haque, M.E.1
Thomas, K.J.2
D'Souza, C.3
Callaghan, S.4
Kitada, T.5
Slack, R.S.6
Fraser, P.7
Cookson, M.R.8
Tandon, A.9
Park, D.S.10
-
35
-
-
17644365438
-
Mutations in PTEN-induced putative kinase 1 associated with recessive Parkinsonism have differential effects on protein stability
-
A. Beilina, M. Van Der Brug, R. Ahmad, S. Kesavapany, D.W. Miller, G.A. Petsko, and M.R. Cookson Mutations in PTEN-induced putative kinase 1 associated with recessive Parkinsonism have differential effects on protein stability Proc. Natl. Acad. Sci. U.S.A. 102 2005 5703 5708
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 5703-5708
-
-
Beilina, A.1
Van Der Brug, M.2
Ahmad, R.3
Kesavapany, S.4
Miller, D.W.5
Petsko, G.A.6
Cookson, M.R.7
-
36
-
-
38849155699
-
Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1
-
A. Weihofen, B. Ostaszewski, Y. Minami, and D.J. Selkoe Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1 Hum. Mol. Genet. 17 2008 602 616
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 602-616
-
-
Weihofen, A.1
Ostaszewski, B.2
Minami, Y.3
Selkoe, D.J.4
-
37
-
-
45249112594
-
Characterization of PINK1 processing, stability, and subcellular localization
-
W. Lin, and U.J. Kang Characterization of PINK1 processing, stability, and subcellular localization J. Neurochem. 106 2008 464 474
-
(2008)
J. Neurochem.
, vol.106
, pp. 464-474
-
-
Lin, W.1
Kang, U.J.2
-
38
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
D. Narendra, A. Tanaka, D.F. Suen, and R.J. Youle Parkin is recruited selectively to impaired mitochondria and promotes their autophagy J. Cell Biol. 183 2008 795 803
-
(2008)
J. Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
39
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with Parkin
-
I.E. Clark, M.W. Dodson, C. Jiang, J.H. Cao, J.R. Huh, J.H. Seol, S.J. Yoo, B.A. Hay, and M. Guo Drosophila pink1 is required for mitochondrial function and interacts genetically with Parkin Nature 441 2006 1162 1166
-
(2006)
Nature
, vol.441
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
40
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
J. Park, S.B. Lee, S. Lee, Y. Kim, S. Song, S. Kim, E. Bae, J. Kim, M. Shong, J.M. Kim, and J. Chung Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin Nature 441 2006 1157 1161
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.M.10
Chung, J.11
-
41
-
-
79952303794
-
Paris (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease
-
J.H. Shin, H.S. Ko, H. Kang, Y. Lee, Y.I. Lee, O. Pletinkova, J.C. Troconso, V.L. Dawson, and T.M. Dawson PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease Cell 144 2011 689 702
-
(2011)
Cell
, vol.144
, pp. 689-702
-
-
Shin, J.H.1
Ko, H.S.2
Kang, H.3
Lee, Y.4
Lee, Y.I.5
Pletinkova, O.6
Troconso, J.C.7
Dawson, V.L.8
Dawson, T.M.9
-
42
-
-
77953084081
-
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
-
L.Y. Hao, B.I. Giasson, and N.M. Bonini DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function Proc. Natl. Acad. Sci. U.S.A. 107 2010 9747 9752
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 9747-9752
-
-
Hao, L.Y.1
Giasson, B.I.2
Bonini, N.M.3
-
43
-
-
78649866553
-
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
-
J.N. Guzman, J. Sanchez-Padilla, D. Wokosin, J. Kondapalli, E. Ilijic, P.T. Schumacker, and D.J. Surmeier Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1 Nature 468 2010 696 700
-
(2010)
Nature
, vol.468
, pp. 696-700
-
-
Guzman, J.N.1
Sanchez-Padilla, J.2
Wokosin, D.3
Kondapalli, J.4
Ilijic, E.5
Schumacker, P.T.6
Surmeier, D.J.7
-
44
-
-
84860539187
-
Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction
-
X. Wang, T.G. Petrie, Y. Liu, J. Liu, H. Fujioka, and X. Zhu Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction J. Neurochem. 121 2012 830 839
-
(2012)
J. Neurochem.
, vol.121
, pp. 830-839
-
-
Wang, X.1
Petrie, T.G.2
Liu, Y.3
Liu, J.4
Fujioka, H.5
Zhu, X.6
-
45
-
-
35548972027
-
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
-
E. Andres-Mateos, C. Perier, L. Zhang, B. Blanchard-Fillion, T.M. Greco, B. Thomas, H.S. Ko, M. Sasaki, H. Ischiropoulos, S. Przedborski, T.M. Dawson, and V.L. Dawson DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase Proc. Natl. Acad. Sci. U.S.A. 104 2007 14807 14812
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 14807-14812
-
-
Andres-Mateos, E.1
Perier, C.2
Zhang, L.3
Blanchard-Fillion, B.4
Greco, T.M.5
Thomas, B.6
Ko, H.S.7
Sasaki, M.8
Ischiropoulos, H.9
Przedborski, S.10
Dawson, T.M.11
Dawson, V.L.12
-
46
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
I. Irrcher, H. Aleyasin, E.L. Seifert, S.J. Hewitt, S. Chhabra, M. Phillips, A.K. Lutz, M.W. Rousseaux, L. Bevilacqua, A. Jahani-Asl, S. Callaghan, J.G. MacLaurin, K.F. Winklhofer, P. Rizzu, P. Rippstein, R.H. Kim, C.X. Chen, E.A. Fon, R.S. Slack, M.E. Harper, H.M. McBride, T.W. Mak, and D.S. Park Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics Hum. Mol. Genet. 19 2010 3734 3746
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
Lutz, A.K.7
Rousseaux, M.W.8
Bevilacqua, L.9
Jahani-Asl, A.10
Callaghan, S.11
MacLaurin, J.G.12
Winklhofer, K.F.13
Rizzu, P.14
Rippstein, P.15
Kim, R.H.16
Chen, C.X.17
Fon, E.A.18
Slack, R.S.19
Harper, M.E.20
McBride, H.M.21
Mak, T.W.22
Park, D.S.23
more..
-
47
-
-
77958450202
-
Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1
-
F. Kamp, N. Exner, A.K. Lutz, N. Wender, J. Hegermann, B. Brunner, B. Nuscher, T. Bartels, A. Giese, K. Beyer, S. Eimer, K.F. Winklhofer, and C. Haass Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1 EMBO J. 29 2010 3571 3589
-
(2010)
EMBO J.
, vol.29
, pp. 3571-3589
-
-
Kamp, F.1
Exner, N.2
Lutz, A.K.3
Wender, N.4
Hegermann, J.5
Brunner, B.6
Nuscher, B.7
Bartels, T.8
Giese, A.9
Beyer, K.10
Eimer, S.11
Winklhofer, K.F.12
Haass, C.13
-
48
-
-
33746594215
-
A regulated interaction with the UIM protein Eps15 implicates Parkin in EGF receptor trafficking and PI(3)K-Akt signalling
-
L. Fallon, C.M. Belanger, A.T. Corera, M. Kontogiannea, E. Regan-Klapisz, F. Moreau, J. Voortman, M. Haber, G. Rouleau, T. Thorarinsdottir, A. Brice, P.M. van Bergen En Henegouwen, and E.A. Fon A regulated interaction with the UIM protein Eps15 implicates Parkin in EGF receptor trafficking and PI(3)K-Akt signalling Nat. Cell Biol. 8 2006 834 842
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 834-842
-
-
Fallon, L.1
Belanger, C.M.2
Corera, A.T.3
Kontogiannea, M.4
Regan-Klapisz, E.5
Moreau, F.6
Voortman, J.7
Haber, M.8
Rouleau, G.9
Thorarinsdottir, T.10
Brice, A.11
Van Bergen En Henegouwen, P.M.12
Fon, E.A.13
-
49
-
-
58149393853
-
Direct binding with histone deacetylase 6 mediates the reversible recruitment of parkin to the centrosome
-
Q. Jiang, Y. Ren, and J. Feng Direct binding with histone deacetylase 6 mediates the reversible recruitment of parkin to the centrosome J. Neurosci. 28 2008 12993 13002
-
(2008)
J. Neurosci.
, vol.28
, pp. 12993-13002
-
-
Jiang, Q.1
Ren, Y.2
Feng, J.3
-
50
-
-
70449519412
-
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease
-
C.A. da Costa, C. Sunyach, E. Giaime, A. West, O. Corti, A. Brice, S. Safe, P.M. Abou-Sleiman, N.W. Wood, H. Takahashi, M.S. Goldberg, J. Shen, and F. Checler Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease Nat. Cell Biol. 11 2009 1370 1375
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1370-1375
-
-
Da Costa, C.A.1
Sunyach, C.2
Giaime, E.3
West, A.4
Corti, O.5
Brice, A.6
Safe, S.7
Abou-Sleiman, P.M.8
Wood, N.W.9
Takahashi, H.10
Goldberg, M.S.11
Shen, J.12
Checler, F.13
-
52
-
-
84878709844
-
Neuroprotective function of DJ-1 in Parkinson's disease
-
H. Ariga, K. Takahashi-Niki, I. Kato, H. Maita, T. Niki, and S.M. Iguchi-Ariga Neuroprotective function of DJ-1 in Parkinson's disease Oxid. Med. Cell Longev. 2013 2013 683920
-
(2013)
Oxid. Med. Cell Longev.
, vol.2013
, pp. 683920
-
-
Ariga, H.1
Takahashi-Niki, K.2
Kato, I.3
Maita, H.4
Niki, T.5
Iguchi-Ariga, S.M.6
-
53
-
-
84923226964
-
CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: A genome-wide linkage and sequencing study
-
M. Funayama, K. Ohe, T. Amo, N. Furuya, J. Yamaguchi, S. Saiki, Y. Li, K. Ogaki, M. Ando, H. Yoshino, H. Tomiyama, K. Nishioka, K. Hasegawa, H. Saiki, W. Satake, K. Mogushi, R. Sasaki, Y. Kokubo, S. Kuzuhara, T. Toda, Y. Mizuno, Y. Uchiyama, K. Ohno, and N. Hattori CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study Lancet Neurol. 14 2015 274 282
-
(2015)
Lancet Neurol.
, vol.14
, pp. 274-282
-
-
Funayama, M.1
Ohe, K.2
Amo, T.3
Furuya, N.4
Yamaguchi, J.5
Saiki, S.6
Li, Y.7
Ogaki, K.8
Ando, M.9
Yoshino, H.10
Tomiyama, H.11
Nishioka, K.12
Hasegawa, K.13
Saiki, H.14
Satake, W.15
Mogushi, K.16
Sasaki, R.17
Kokubo, Y.18
Kuzuhara, S.19
Toda, T.20
Mizuno, Y.21
Uchiyama, Y.22
Ohno, K.23
Hattori, N.24
more..
-
54
-
-
84911916147
-
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism
-
S. Aras, M. Bai, I. Lee, R. Springett, M. Huttemann, and L.I. Grossman MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism Mitochondrion 20 2015 43 51
-
(2015)
Mitochondrion
, vol.20
, pp. 43-51
-
-
Aras, S.1
Bai, M.2
Lee, I.3
Springett, R.4
Huttemann, M.5
Grossman, L.I.6
-
55
-
-
67849130819
-
A computational screen for regulators of oxidative phosphorylation implicates SLIRP in mitochondrial RNA homeostasis
-
J.M. Baughman, R. Nilsson, V.M. Gohil, D.H. Arlow, Z. Gauhar, and V.K. Mootha A computational screen for regulators of oxidative phosphorylation implicates SLIRP in mitochondrial RNA homeostasis PLoS Genet. 5 2009 e1000590
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000590
-
-
Baughman, J.M.1
Nilsson, R.2
Gohil, V.M.3
Arlow, D.H.4
Gauhar, Z.5
Mootha, V.K.6
-
56
-
-
79957974579
-
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein
-
K. Nakamura, V.M. Nemani, F. Azarbal, G. Skibinski, J.M. Levy, K. Egami, L. Munishkina, J. Zhang, B. Gardner, J. Wakabayashi, H. Sesaki, Y. Cheng, S. Finkbeiner, R.L. Nussbaum, E. Masliah, and R.H. Edwards Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein J. Biol. Chem. 286 2011 20710 20726
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 20710-20726
-
-
Nakamura, K.1
Nemani, V.M.2
Azarbal, F.3
Skibinski, G.4
Levy, J.M.5
Egami, K.6
Munishkina, L.7
Zhang, J.8
Gardner, B.9
Wakabayashi, J.10
Sesaki, H.11
Cheng, Y.12
Finkbeiner, S.13
Nussbaum, R.L.14
Masliah, E.15
Edwards, R.H.16
-
57
-
-
44049099669
-
Mitochondrial import and accumulation of alpha-synuclein impair complex i in human dopaminergic neuronal cultures and Parkinson disease brain
-
L. Devi, V. Raghavendran, B.M. Prabhu, N.G. Avadhani, and H.K. Anandatheerthavarada Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain J. Biol. Chem. 283 2008 9089 9100
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
58
-
-
77951239770
-
The transgenic over expression of alpha-synuclein and not its related pathology, associates with complex i inhibition
-
V. Loeb, E. Yakunin, A. Saada, and R. Sharon The transgenic over expression of alpha-synuclein and not its related pathology, associates with complex I inhibition J. Biol. Chem. 285 2010 7334 7343
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 7334-7343
-
-
Loeb, V.1
Yakunin, E.2
Saada, A.3
Sharon, R.4
-
59
-
-
84879918450
-
Alpha-synuclein and mitochondria: Partners in crime?
-
K. Nakamura Alpha-synuclein and mitochondria: partners in crime? Neurotherapeutics 10 2013 391 399
-
(2013)
Neurotherapeutics
, vol.10
, pp. 391-399
-
-
Nakamura, K.1
-
61
-
-
67651171368
-
LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans
-
S. Saha, M.D. Guillily, A. Ferree, J. Lanceta, D. Chan, J. Ghosh, C.H. Hsu, L. Segal, K. Raghavan, K. Matsumoto, N. Hisamoto, T. Kuwahara, T. Iwatsubo, L. Moore, L. Goldstein, M. Cookson, and B. Wolozin LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans J. Neurosci. 29 2009 9210 9218
-
(2009)
J. Neurosci.
, vol.29
, pp. 9210-9218
-
-
Saha, S.1
Guillily, M.D.2
Ferree, A.3
Lanceta, J.4
Chan, D.5
Ghosh, J.6
Hsu, C.H.7
Segal, L.8
Raghavan, K.9
Matsumoto, K.10
Hisamoto, N.11
Kuwahara, T.12
Iwatsubo, T.13
Moore, L.14
Goldstein, L.15
Cookson, M.16
Wolozin, B.17
-
62
-
-
84863584524
-
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease
-
O. Cooper, H. Seo, S. Andrabi, C. Guardia-Laguarta, J. Graziotto, M. Sundberg, J.R. McLean, L. Carrillo-Reid, Z. Xie, T. Osborn, G. Hargus, M. Deleidi, T. Lawson, H. Bogetofte, E. Perez-Torres, L. Clark, C. Moskowitz, J. Mazzulli, L. Chen, L. Volpicelli-Daley, N. Romero, H. Jiang, R.J. Uitti, Z. Huang, G. Opala, L.A. Scarffe, V.L. Dawson, C. Klein, J. Feng, O.A. Ross, J.Q. Trojanowski, V.M. Lee, K. Marder, D.J. Surmeier, Z.K. Wszolek, S. Przedborski, D. Krainc, T.M. Dawson, and O. Isacson Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease Sci. Transl. Med. 4 2012 141ra90
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 141ra90
-
-
Cooper, O.1
Seo, H.2
Andrabi, S.3
Guardia-Laguarta, C.4
Graziotto, J.5
Sundberg, M.6
McLean, J.R.7
Carrillo-Reid, L.8
Xie, Z.9
Osborn, T.10
Hargus, G.11
Deleidi, M.12
Lawson, T.13
Bogetofte, H.14
Perez-Torres, E.15
Clark, L.16
Moskowitz, C.17
Mazzulli, J.18
Chen, L.19
Volpicelli-Daley, L.20
Romero, N.21
Jiang, H.22
Uitti, R.J.23
Huang, Z.24
Opala, G.25
Scarffe, L.A.26
Dawson, V.L.27
Klein, C.28
Feng, J.29
Ross, O.A.30
Trojanowski, J.Q.31
Lee, V.M.32
Marder, K.33
Surmeier, D.J.34
Wszolek, Z.K.35
Przedborski, S.36
Krainc, D.37
Dawson, T.M.38
Isacson, O.39
more..
-
63
-
-
84872691988
-
Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons
-
S.J. Cherra 3rd, E. Steer, A.M. Gusdon, K. Kiselyov, and C.T. Chu Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons Am. J. Pathol. 182 2013 474 484
-
(2013)
Am. J. Pathol.
, vol.182
, pp. 474-484
-
-
Cherra, S.J.1
Steer, E.2
Gusdon, A.M.3
Kiselyov, K.4
Chu, C.T.5
-
64
-
-
84859259002
-
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1
-
X. Wang, M.H. Yan, H. Fujioka, J. Liu, A. Wilson-Delfosse, S.G. Chen, G. Perry, G. Casadesus, and X. Zhu LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1 Hum. Mol. Genet. 21 2012 1931 1944
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 1931-1944
-
-
Wang, X.1
Yan, M.H.2
Fujioka, H.3
Liu, J.4
Wilson-Delfosse, A.5
Chen, S.G.6
Perry, G.7
Casadesus, G.8
Zhu, X.9
-
65
-
-
84887506882
-
LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction
-
L.H. Sanders, J. Laganiere, O. Cooper, S.K. Mak, B.J. Vu, Y.A. Huang, D.E. Paschon, M. Vangipuram, R. Sundararajan, F.D. Urnov, J.W. Langston, P.D. Gregory, H.S. Zhang, J.T. Greenamyre, O. Isacson, and B. Schule LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction Neurobiol. Dis. 62 2014 381 386
-
(2014)
Neurobiol. Dis.
, vol.62
, pp. 381-386
-
-
Sanders, L.H.1
Laganiere, J.2
Cooper, O.3
Mak, S.K.4
Vu, B.J.5
Huang, Y.A.6
Paschon, D.E.7
Vangipuram, M.8
Sundararajan, R.9
Urnov, F.D.10
Langston, J.W.11
Gregory, P.D.12
Zhang, H.S.13
Greenamyre, J.T.14
Isacson, O.15
Schule, B.16
-
66
-
-
70450224253
-
Parkin and PINK1 Parkinsonism may represent nigral mitochondrial cytopathies distinct from Lewy body Parkinson's disease
-
J.E. Ahlskog Parkin and PINK1 Parkinsonism may represent nigral mitochondrial cytopathies distinct from Lewy body Parkinson's disease Parkinsonism Relat. Disord. 15 2009 721 727
-
(2009)
Parkinsonism Relat. Disord.
, vol.15
, pp. 721-727
-
-
Ahlskog, J.E.1
-
67
-
-
77950613042
-
A comparative study of LRRK2, PINK1 and genetically undefined familial Parkinson's disease
-
K. Nishioka, M. Kefi, B. Jasinska-Myga, C. Wider, C. Vilarino-Guell, O.A. Ross, M.G. Heckman, L.T. Middleton, L. Ishihara-Paul, R.A. Gibson, R. Amouri, S. Ben Yahmed, S. Ben Sassi, M. Zouari, G. El Euch, M.J. Farrer, and F. Hentati A comparative study of LRRK2, PINK1 and genetically undefined familial Parkinson's disease J. Neurol. Neurosurg. Psychiatry 81 2010 391 395
-
(2010)
J. Neurol. Neurosurg. Psychiatry
, vol.81
, pp. 391-395
-
-
Nishioka, K.1
Kefi, M.2
Jasinska-Myga, B.3
Wider, C.4
Vilarino-Guell, C.5
Ross, O.A.6
Heckman, M.G.7
Middleton, L.T.8
Ishihara-Paul, L.9
Gibson, R.A.10
Amouri, R.11
Ben Yahmed, S.12
Ben Sassi, S.13
Zouari, M.14
El Euch, G.15
Farrer, M.J.16
Hentati, F.17
-
68
-
-
0033933192
-
Parkin deletions in a family with adult-onset, tremor-dominant Parkinsonism: Expanding the phenotype
-
C. Klein, P.P. Pramstaller, B. Kis, C.C. Page, M. Kann, J. Leung, H. Woodward, C.C. Castellan, M. Scherer, P. Vieregge, X.O. Breakefield, P.L. Kramer, and L.J. Ozelius Parkin deletions in a family with adult-onset, tremor-dominant Parkinsonism: expanding the phenotype Ann. Neurol. 48 2000 65 71
-
(2000)
Ann. Neurol.
, vol.48
, pp. 65-71
-
-
Klein, C.1
Pramstaller, P.P.2
Kis, B.3
Page, C.C.4
Kann, M.5
Leung, J.6
Woodward, H.7
Castellan, C.C.8
Scherer, M.9
Vieregge, P.10
Breakefield, X.O.11
Kramer, P.L.12
Ozelius, L.J.13
-
69
-
-
77957043835
-
Frequency of known mutations in early-onset Parkinson disease: Implication for genetic counseling: The consortium on risk for early onset Parkinson disease study
-
R.N. Alcalay, E. Caccappolo, H. Mejia-Santana, M.X. Tang, L. Rosado, B.M. Ross, M. Verbitsky, S. Kisselev, E.D. Louis, C. Comella, A. Colcher, D. Jennings, M.A. Nance, S.B. Bressman, W.K. Scott, C. Tanner, S. Mickel, H. Andrews, C. Waters, S. Fahn, L. Cote, S. Frucht, B. Ford, M. Rezak, K. Novak, J.H. Friedman, R. Pfeiffer, L. Marsh, B. Hiner, A. Siderowf, R. Ottman, K. Marder, and L.N. Clark Frequency of known mutations in early-onset Parkinson disease: implication for genetic counseling: the consortium on risk for early onset Parkinson disease study Arch. Neurol. 67 2010 1116 1122
-
(2010)
Arch. Neurol.
, vol.67
, pp. 1116-1122
-
-
Alcalay, R.N.1
Caccappolo, E.2
Mejia-Santana, H.3
Tang, M.X.4
Rosado, L.5
Ross, B.M.6
Verbitsky, M.7
Kisselev, S.8
Louis, E.D.9
Comella, C.10
Colcher, A.11
Jennings, D.12
Nance, M.A.13
Bressman, S.B.14
Scott, W.K.15
Tanner, C.16
Mickel, S.17
Andrews, H.18
Waters, C.19
Fahn, S.20
Cote, L.21
Frucht, S.22
Ford, B.23
Rezak, M.24
Novak, K.25
Friedman, J.H.26
Pfeiffer, R.27
Marsh, L.28
Hiner, B.29
Siderowf, A.30
Ottman, R.31
Marder, K.32
Clark, L.N.33
more..
-
70
-
-
61649104022
-
Genotypic and phenotypic characteristics of Dutch patients with early onset Parkinson's disease
-
M.G. Macedo, D. Verbaan, Y. Fang, S.M. van Rooden, M. Visser, B. Anar, A. Uras, J.L. Groen, P. Rizzu, J.J. van Hilten, and P. Heutink Genotypic and phenotypic characteristics of Dutch patients with early onset Parkinson's disease Mov. Disord. 24 2009 196 203
-
(2009)
Mov. Disord.
, vol.24
, pp. 196-203
-
-
Macedo, M.G.1
Verbaan, D.2
Fang, Y.3
Van Rooden, S.M.4
Visser, M.5
Anar, B.6
Uras, A.7
Groen, J.L.8
Rizzu, P.9
Van Hilten, J.J.10
Heutink, P.11
-
71
-
-
84892375063
-
Cognitive and motor function in long-duration PARKIN-associated Parkinson disease
-
R.N. Alcalay, E. Caccappolo, H. Mejia-Santana, M.X. Tang, L. Rosado, M. Orbe Reilly, D. Ruiz, E.D. Louis, C.L. Comella, M.A. Nance, S.B. Bressman, W.K. Scott, C.M. Tanner, S.F. Mickel, C.H. Waters, S. Fahn, L.J. Cote, S.J. Frucht, B. Ford, M. Rezak, K.E. Novak, J.H. Friedman, R.F. Pfeiffer, L. Marsh, B. Hiner, H. Payami, E. Molho, S.A. Factor, J.G. Nutt, C. Serrano, M. Arroyo, R. Ottman, M.W. Pauciulo, W.C. Nichols, L.N. Clark, and K.S. Marder Cognitive and motor function in long-duration PARKIN-associated Parkinson disease JAMA Neurol. 71 2014 62 67
-
(2014)
JAMA Neurol.
, vol.71
, pp. 62-67
-
-
Alcalay, R.N.1
Caccappolo, E.2
Mejia-Santana, H.3
Tang, M.X.4
Rosado, L.5
Orbe Reilly, M.6
Ruiz, D.7
Louis, E.D.8
Comella, C.L.9
Nance, M.A.10
Bressman, S.B.11
Scott, W.K.12
Tanner, C.M.13
Mickel, S.F.14
Waters, C.H.15
Fahn, S.16
Cote, L.J.17
Frucht, S.J.18
Ford, B.19
Rezak, M.20
Novak, K.E.21
Friedman, J.H.22
Pfeiffer, R.F.23
Marsh, L.24
Hiner, B.25
Payami, H.26
Molho, E.27
Factor, S.A.28
Nutt, J.G.29
Serrano, C.30
Arroyo, M.31
Ottman, R.32
Pauciulo, M.W.33
Nichols, W.C.34
Clark, L.N.35
Marder, K.S.36
more..
-
72
-
-
60549116319
-
A multidisciplinary study of patients with early-onset PD with and without parkin mutations
-
E. Lohmann, S. Thobois, S. Lesage, E. Broussolle, S.T. du Montcel, M.J. Ribeiro, P. Remy, A. Pelissolo, B. Dubois, L. Mallet, P. Pollak, Y. Agid, and A. Brice A multidisciplinary study of patients with early-onset PD with and without parkin mutations Neurology 72 2009 110 116
-
(2009)
Neurology
, vol.72
, pp. 110-116
-
-
Lohmann, E.1
Thobois, S.2
Lesage, S.3
Broussolle, E.4
Du Montcel, S.T.5
Ribeiro, M.J.6
Remy, P.7
Pelissolo, A.8
Dubois, B.9
Mallet, L.10
Pollak, P.11
Agid, Y.12
Brice, A.13
-
73
-
-
79451474061
-
Neuropsychological profile of parkin mutation carriers with and without Parkinson disease: The CORE-PD study
-
E. Caccappolo, R.N. Alcalay, H. Mejia-Santana, M.X. Tang, B. Rakitin, L. Rosado, E.D. Louis, C.L. Comella, A. Colcher, D. Jennings, M.A. Nance, S. Bressman, W.K. Scott, C.M. Tanner, S.F. Mickel, H.F. Andrews, C. Waters, S. Fahn, L.J. Cote, S. Frucht, B. Ford, M. Rezak, K. Novak, J.H. Friedman, R.F. Pfeiffer, L. Marsh, B. Hiner, A.D. Siderowf, B.M. Ross, M. Verbitsky, S. Kisselev, R. Ottman, L.N. Clark, and K.S. Marder Neuropsychological profile of parkin mutation carriers with and without Parkinson disease: the CORE-PD study J. Int. Neuropsychol. Soc. 17 2011 91 100
-
(2011)
J. Int. Neuropsychol. Soc.
, vol.17
, pp. 91-100
-
-
Caccappolo, E.1
Alcalay, R.N.2
Mejia-Santana, H.3
Tang, M.X.4
Rakitin, B.5
Rosado, L.6
Louis, E.D.7
Comella, C.L.8
Colcher, A.9
Jennings, D.10
Nance, M.A.11
Bressman, S.12
Scott, W.K.13
Tanner, C.M.14
Mickel, S.F.15
Andrews, H.F.16
Waters, C.17
Fahn, S.18
Cote, L.J.19
Frucht, S.20
Ford, B.21
Rezak, M.22
Novak, K.23
Friedman, J.H.24
Pfeiffer, R.F.25
Marsh, L.26
Hiner, B.27
Siderowf, A.D.28
Ross, B.M.29
Verbitsky, M.30
Kisselev, S.31
Ottman, R.32
Clark, L.N.33
Marder, K.S.34
more..
-
74
-
-
84875226362
-
Parkinson's disease subtypes: Lost in translation?
-
C. Marras, and A. Lang Parkinson's disease subtypes: lost in translation? J. Neurol. Neurosurg. Psychiatry 84 2013 409 415
-
(2013)
J. Neurol. Neurosurg. Psychiatry
, vol.84
, pp. 409-415
-
-
Marras, C.1
Lang, A.2
-
76
-
-
0242300619
-
Alpha-synuclein locus triplication causes Parkinson's disease
-
A.B. Singleton, M. Farrer, J. Johnson, A. Singleton, S. Hague, J. Kachergus, M. Hulihan, T. Peuralinna, A. Dutra, R. Nussbaum, S. Lincoln, A. Crawley, M. Hanson, D. Maraganore, C. Adler, M.R. Cookson, M. Muenter, M. Baptista, D. Miller, J. Blancato, J. Hardy, and K. Gwinn-Hardy Alpha-synuclein locus triplication causes Parkinson's disease Science 302 2003 841
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
77
-
-
4644236043
-
Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease
-
P. Ibanez, A.M. Bonnet, B. Debarges, E. Lohmann, F. Tison, P. Pollak, Y. Agid, A. Durr, and A. Brice Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease Lancet 364 2004 1169 1171
-
(2004)
Lancet
, vol.364
, pp. 1169-1171
-
-
Ibanez, P.1
Bonnet, A.M.2
Debarges, B.3
Lohmann, E.4
Tison, F.5
Pollak, P.6
Agid, Y.7
Durr, A.8
Brice, A.9
-
78
-
-
10744227740
-
Comparison of kindreds with Parkinsonism and alpha-synuclein genomic multiplications
-
M. Farrer, J. Kachergus, L. Forno, S. Lincoln, D.S. Wang, M. Hulihan, D. Maraganore, K. Gwinn-Hardy, Z. Wszolek, D. Dickson, and J.W. Langston Comparison of kindreds with Parkinsonism and alpha-synuclein genomic multiplications Ann Neurol. 55 2004 174 179
-
(2004)
Ann Neurol.
, vol.55
, pp. 174-179
-
-
Farrer, M.1
Kachergus, J.2
Forno, L.3
Lincoln, S.4
Wang, D.S.5
Hulihan, M.6
Maraganore, D.7
Gwinn-Hardy, K.8
Wszolek, Z.9
Dickson, D.10
Langston, J.W.11
-
79
-
-
0034848395
-
Lewy bodies and Parkinsonism in families with parkin mutations
-
M. Farrer, P. Chan, R. Chen, L. Tan, S. Lincoln, D. Hernandez, L. Forno, K. Gwinn-Hardy, L. Petrucelli, J. Hussey, A. Singleton, C. Tanner, J. Hardy, and J.W. Langston Lewy bodies and Parkinsonism in families with parkin mutations Ann. Neurol. 50 2001 293 300
-
(2001)
Ann. Neurol.
, vol.50
, pp. 293-300
-
-
Farrer, M.1
Chan, P.2
Chen, R.3
Tan, L.4
Lincoln, S.5
Hernandez, D.6
Forno, L.7
Gwinn-Hardy, K.8
Petrucelli, L.9
Hussey, J.10
Singleton, A.11
Tanner, C.12
Hardy, J.13
Langston, J.W.14
-
80
-
-
24644462201
-
Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers
-
P.P. Pramstaller, M.G. Schlossmacher, T.S. Jacques, F. Scaravilli, C. Eskelson, I. Pepivani, K. Hedrich, S. Adel, M. Gonzales-McNeal, R. Hilker, P.L. Kramer, and C. Klein Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers Ann. Neurol. 58 2005 411 422
-
(2005)
Ann. Neurol.
, vol.58
, pp. 411-422
-
-
Pramstaller, P.P.1
Schlossmacher, M.G.2
Jacques, T.S.3
Scaravilli, F.4
Eskelson, C.5
Pepivani, I.6
Hedrich, K.7
Adel, S.8
Gonzales-McNeal, M.9
Hilker, R.10
Kramer, P.L.11
Klein, C.12
-
81
-
-
77950855127
-
PINK1-linked Parkinsonism is associated with Lewy body pathology
-
L. Samaranch, O. Lorenzo-Betancor, J.M. Arbelo, I. Ferrer, E. Lorenzo, J. Irigoyen, M.A. Pastor, C. Marrero, C. Isla, J. Herrera-Henriquez, and P. Pastor PINK1-linked Parkinsonism is associated with Lewy body pathology Brain 133 2010 1128 1142
-
(2010)
Brain
, vol.133
, pp. 1128-1142
-
-
Samaranch, L.1
Lorenzo-Betancor, O.2
Arbelo, J.M.3
Ferrer, I.4
Lorenzo, E.5
Irigoyen, J.6
Pastor, M.A.7
Marrero, C.8
Isla, C.9
Herrera-Henriquez, J.10
Pastor, P.11
-
82
-
-
2342605968
-
Autosomal dominant Parkinsonism associated with variable synuclein and tau pathology
-
Z.K. Wszolek, R.F. Pfeiffer, Y. Tsuboi, R.J. Uitti, R.D. McComb, A.J. Stoessl, A.J. Strongosky, A. Zimprich, B. Muller-Myhsok, M.J. Farrer, T. Gasser, D.B. Calne, and D.W. Dickson Autosomal dominant Parkinsonism associated with variable synuclein and tau pathology Neurology 62 2004 1619 1622
-
(2004)
Neurology
, vol.62
, pp. 1619-1622
-
-
Wszolek, Z.K.1
Pfeiffer, R.F.2
Tsuboi, Y.3
Uitti, R.J.4
McComb, R.D.5
Stoessl, A.J.6
Strongosky, A.J.7
Zimprich, A.8
Muller-Myhsok, B.9
Farrer, M.J.10
Gasser, T.11
Calne, D.B.12
Dickson, D.W.13
-
83
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
-
A. Zimprich, S. Biskup, P. Leitner, P. Lichtner, M. Farrer, S. Lincoln, J. Kachergus, M. Hulihan, R.J. Uitti, D.B. Calne, A.J. Stoessl, R.F. Pfeiffer, N. Patenge, I.C. Carbajal, P. Vieregge, F. Asmus, B. Muller-Myhsok, D.W. Dickson, T. Meitinger, T.M. Strom, Z.K. Wszolek, and T. Gasser Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology Neuron 44 2004 601 607
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
Stoessl, A.J.11
Pfeiffer, R.F.12
Patenge, N.13
Carbajal, I.C.14
Vieregge, P.15
Asmus, F.16
Muller-Myhsok, B.17
Dickson, D.W.18
Meitinger, T.19
Strom, T.M.20
Wszolek, Z.K.21
Gasser, T.22
more..
-
84
-
-
0031721141
-
Pathologic and biochemical studies of juvenile Parkinsonism linked to chromosome 6q
-
H. Mori, T. Kondo, M. Yokochi, H. Matsumine, Y. Nakagawa-Hattori, T. Miyake, K. Suda, and Y. Mizuno Pathologic and biochemical studies of juvenile Parkinsonism linked to chromosome 6q Neurology 51 1998 890 892
-
(1998)
Neurology
, vol.51
, pp. 890-892
-
-
Mori, H.1
Kondo, T.2
Yokochi, M.3
Matsumine, H.4
Nakagawa-Hattori, Y.5
Miyake, T.6
Suda, K.7
Mizuno, Y.8
-
85
-
-
33750440495
-
Hippocampal neuron and glial cell numbers in Parkinson's disease- A stereological study
-
F.C. Joelving, R. Billeskov, J.R. Christensen, M. West, and B. Pakkenberg Hippocampal neuron and glial cell numbers in Parkinson's disease-a stereological study Hippocampus 16 2006 826 833
-
(2006)
Hippocampus
, vol.16
, pp. 826-833
-
-
Joelving, F.C.1
Billeskov, R.2
Christensen, J.R.3
West, M.4
Pakkenberg, B.5
-
86
-
-
33646109064
-
Alpha-synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals
-
K.J. Klos, J.E. Ahlskog, K.A. Josephs, H. Apaydin, J.E. Parisi, B.F. Boeve, M.W. DeLucia, and D.W. Dickson Alpha-synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals Neurology 66 2006 1100 1102
-
(2006)
Neurology
, vol.66
, pp. 1100-1102
-
-
Klos, K.J.1
Ahlskog, J.E.2
Josephs, K.A.3
Apaydin, H.4
Parisi, J.E.5
Boeve, B.F.6
DeLucia, M.W.7
Dickson, D.W.8
-
87
-
-
57749095477
-
A critical evaluation of the Braak staging scheme for Parkinson's disease
-
R.E. Burke, W.T. Dauer, and J.P. Vonsattel A critical evaluation of the Braak staging scheme for Parkinson's disease Ann. Neurol. 64 2008 485 491
-
(2008)
Ann. Neurol.
, vol.64
, pp. 485-491
-
-
Burke, R.E.1
Dauer, W.T.2
Vonsattel, J.P.3
-
88
-
-
71849092190
-
Neuropathological assessment of Parkinson's disease: Refining the diagnostic criteria
-
D.W. Dickson, H. Braak, J.E. Duda, C. Duyckaerts, T. Gasser, G.M. Halliday, J. Hardy, J.B. Leverenz, K. Del Tredici, Z.K. Wszolek, and I. Litvan Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria Lancet Neurol. 8 2009 1150 1157
-
(2009)
Lancet Neurol.
, vol.8
, pp. 1150-1157
-
-
Dickson, D.W.1
Braak, H.2
Duda, J.E.3
Duyckaerts, C.4
Gasser, T.5
Halliday, G.M.6
Hardy, J.7
Leverenz, J.B.8
Del Tredici, K.9
Wszolek, Z.K.10
Litvan, I.11
-
89
-
-
11144241275
-
Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia
-
L. Parkkinen, T. Kauppinen, T. Pirttila, J.M. Autere, and I. Alafuzoff Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia Ann. Neurol. 57 2005 82 91
-
(2005)
Ann. Neurol.
, vol.57
, pp. 82-91
-
-
Parkkinen, L.1
Kauppinen, T.2
Pirttila, T.3
Autere, J.M.4
Alafuzoff, I.5
-
90
-
-
0025254401
-
Mitochondrial complex i deficiency in Parkinson's disease
-
A.H. Schapira, J.M. Cooper, D. Dexter, J.B. Clark, P. Jenner, and C.D. Marsden Mitochondrial complex I deficiency in Parkinson's disease J. Neurochem. 54 1990 823 827
-
(1990)
J. Neurochem.
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
91
-
-
0027995435
-
Complex I, iron, and ferritin in Parkinson's disease substantia nigra
-
V.M. Mann, J.M. Cooper, S.E. Daniel, K. Srai, P. Jenner, C.D. Marsden, and A.H.V. Schapira Complex I, iron, and ferritin in Parkinson's disease substantia nigra Ann. Neurol. 36 1994 876 881
-
(1994)
Ann. Neurol.
, vol.36
, pp. 876-881
-
-
Mann, V.M.1
Cooper, J.M.2
Daniel, S.E.3
Srai, K.4
Jenner, P.5
Marsden, C.D.6
Schapira, A.H.V.7
-
92
-
-
0029050583
-
Low platelet mitochondrial complex i and complex II/III activity in early untreated Parkinson's disease
-
R.H. Haas, F. Nasirian, K. Nakano, D. Ward, M. Pay, R. Hill, and C.W. Shults Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease Ann. Neurol. 37 1995 714 722
-
(1995)
Ann. Neurol.
, vol.37
, pp. 714-722
-
-
Haas, R.H.1
Nasirian, F.2
Nakano, K.3
Ward, D.4
Pay, M.5
Hill, R.6
Shults, C.W.7
-
93
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
W.D. Parker Jr., S.J. Boyson, and J.K. Parks Abnormalities of the electron transport chain in idiopathic Parkinson's disease Ann. Neurol. 26 1989 719 723
-
(1989)
Ann. Neurol.
, vol.26
, pp. 719-723
-
-
Parker, W.D.1
Boyson, S.J.2
Parks, J.K.3
-
94
-
-
77958072667
-
PGC-1alpha, a potential therapeutic target for early intervention in Parkinson's disease
-
B. Zheng, Z. Liao, J.J. Locascio, K.A. Lesniak, S.S. Roderick, M.L. Watt, A.C. Eklund, Y. Zhang-James, P.D. Kim, M.A. Hauser, E. Grunblatt, L.B. Moran, S.A. Mandel, P. Riederer, R.M. Miller, H.J. Federoff, U. Wullner, S. Papapetropoulos, M.B. Youdim, I. Cantuti-Castelvetri, A.B. Young, J.M. Vance, R.L. Davis, J.C. Hedreen, C.H. Adler, T.G. Beach, M.B. Graeber, F.A. Middleton, J.C. Rochet, and C.R. Scherzer PGC-1alpha, a potential therapeutic target for early intervention in Parkinson's disease Sci. Transl. Med. 2 2010 52ra73
-
(2010)
Sci. Transl. Med.
, vol.2
, pp. 52ra73
-
-
Zheng, B.1
Liao, Z.2
Locascio, J.J.3
Lesniak, K.A.4
Roderick, S.S.5
Watt, M.L.6
Eklund, A.C.7
Zhang-James, Y.8
Kim, P.D.9
Hauser, M.A.10
Grunblatt, E.11
Moran, L.B.12
Mandel, S.A.13
Riederer, P.14
Miller, R.M.15
Federoff, H.J.16
Wullner, U.17
Papapetropoulos, S.18
Youdim, M.B.19
Cantuti-Castelvetri, I.20
Young, A.B.21
Vance, J.M.22
Davis, R.L.23
Hedreen, J.C.24
Adler, C.H.25
Beach, T.G.26
Graeber, M.B.27
Middleton, F.A.28
Rochet, J.C.29
Scherzer, C.R.30
more..
-
95
-
-
79959602140
-
Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death
-
M. Elstner, C.M. Morris, K. Heim, A. Bender, D. Mehta, E. Jaros, T. Klopstock, T. Meitinger, D.M. Turnbull, and H. Prokisch Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death Acta Neuropathol. 122 2011 75 86
-
(2011)
Acta Neuropathol.
, vol.122
, pp. 75-86
-
-
Elstner, M.1
Morris, C.M.2
Heim, K.3
Bender, A.4
Mehta, D.5
Jaros, E.6
Klopstock, T.7
Meitinger, T.8
Turnbull, D.M.9
Prokisch, H.10
-
96
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
A. Bender, K.J. Krishnan, C.M. Morris, G.A. Taylor, A.K. Reeve, R.H. Perry, E. Jaros, J.S. Hersheson, J. Betts, T. Klopstock, R.W. Taylor, and D.M. Turnbull High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease Nat. Genet. 38 2006 515 517
-
(2006)
Nat. Genet.
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
Taylor, R.W.11
Turnbull, D.M.12
-
97
-
-
84861554724
-
Alpha-synuclein controls mitochondrial calcium homeostasis by enhancing endoplasmic reticulum-mitochondria interactions
-
T. Cali, D. Ottolini, A. Negro, and M. Brini Alpha-synuclein controls mitochondrial calcium homeostasis by enhancing endoplasmic reticulum-mitochondria interactions J. Biol. Chem. 287 2012 17914 17929
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 17914-17929
-
-
Cali, T.1
Ottolini, D.2
Negro, A.3
Brini, M.4
-
98
-
-
79953202481
-
Mutant A53T alpha-synuclein induces neuronal death by increasing mitochondrial autophagy
-
V. Choubey, D. Safiulina, A. Vaarmann, M. Cagalinec, P. Wareski, M. Kuum, A. Zharkovsky, and A. Kaasik Mutant A53T alpha-synuclein induces neuronal death by increasing mitochondrial autophagy J. Biol. Chem. 286 2011 10814 10824
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 10814-10824
-
-
Choubey, V.1
Safiulina, D.2
Vaarmann, A.3
Cagalinec, M.4
Wareski, P.5
Kuum, M.6
Zharkovsky, A.7
Kaasik, A.8
-
99
-
-
78049383132
-
Mitochondrial alpha-synuclein accumulation impairs complex i function in dopaminergic neurons and results in increased mitophagy in vivo
-
S.J. Chinta, J.K. Mallajosyula, A. Rane, and J.K. Andersen Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo Neurosci. Lett. 486 2010 235 239
-
(2010)
Neurosci. Lett.
, vol.486
, pp. 235-239
-
-
Chinta, S.J.1
Mallajosyula, J.K.2
Rane, A.3
Andersen, J.K.4
-
100
-
-
84865045728
-
Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson's disease
-
A. Siddiqui, S.J. Chinta, J.K. Mallajosyula, S. Rajagopolan, I. Hanson, A. Rane, S. Melov, and J.K. Andersen Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for Parkinson's disease Free Radical Biol. Med. 53 2012 993 1003
-
(2012)
Free Radical Biol. Med.
, vol.53
, pp. 993-1003
-
-
Siddiqui, A.1
Chinta, S.J.2
Mallajosyula, J.K.3
Rajagopolan, S.4
Hanson, I.5
Rane, A.6
Melov, S.7
Andersen, J.K.8
-
101
-
-
0037195109
-
Resistance of alpha-synuclein null mice to the Parkinsonian neurotoxin MPTP
-
W. Dauer, N. Kholodilov, M. Vila, A.C. Trillat, R. Goodchild, K.E. Larsen, R. Staal, K. Tieu, Y. Schmitz, C.A. Yuan, M. Rocha, V. Jackson-Lewis, S. Hersch, D. Sulzer, S. Przedborski, R. Burke, and R. Hen Resistance of alpha-synuclein null mice to the Parkinsonian neurotoxin MPTP Proc. Natl. Acad. Sci. U.S.A. 99 2002 14524 14529
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 14524-14529
-
-
Dauer, W.1
Kholodilov, N.2
Vila, M.3
Trillat, A.C.4
Goodchild, R.5
Larsen, K.E.6
Staal, R.7
Tieu, K.8
Schmitz, Y.9
Yuan, C.A.10
Rocha, M.11
Jackson-Lewis, V.12
Hersch, S.13
Sulzer, D.14
Przedborski, S.15
Burke, R.16
Hen, R.17
-
102
-
-
33244460534
-
Mice lacking alpha-synuclein are resistant to mitochondrial toxins
-
P. Klivenyi, D. Siwek, G. Gardian, L. Yang, A. Starkov, C. Cleren, R.J. Ferrante, N.W. Kowall, A. Abeliovich, and M.F. Beal Mice lacking alpha-synuclein are resistant to mitochondrial toxins Neurobiol. Dis. 21 2006 541 548
-
(2006)
Neurobiol. Dis.
, vol.21
, pp. 541-548
-
-
Klivenyi, P.1
Siwek, D.2
Gardian, G.3
Yang, L.4
Starkov, A.5
Cleren, C.6
Ferrante, R.J.7
Kowall, N.W.8
Abeliovich, A.9
Beal, M.F.10
-
103
-
-
84930226005
-
Convergence of Parkin, PINK1, and alpha-synuclein on stress-induced mitochondrial morphological remodeling
-
K.L. Norris, R. Hao, L.F. Chen, C.H. Lai, M. Kapur, P.J. Shaughnessy, D. Chou, J. Yan, J.P. Taylor, S. Engelender, A.E. West, K.L. Lim, and T.P. Yao Convergence of Parkin, PINK1, and alpha-synuclein on stress-induced mitochondrial morphological remodeling J. Biol. Chem. 290 2015 13862 13874
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 13862-13874
-
-
Norris, K.L.1
Hao, R.2
Chen, L.F.3
Lai, C.H.4
Kapur, M.5
Shaughnessy, P.J.6
Chou, D.7
Yan, J.8
Taylor, J.P.9
Engelender, S.10
West, A.E.11
Lim, K.L.12
Yao, T.P.13
-
104
-
-
84920920653
-
Mutual exacerbation of peroxisome proliferator-activated receptor gamma coactivator 1alpha deregulation and alpha-synuclein oligomerization
-
J. Eschbach, B. von Einem, K. Muller, H. Bayer, A. Scheffold, B.E. Morrison, K.L. Rudolph, D.R. Thal, A. Witting, P. Weydt, M. Otto, M. Fauler, B. Liss, P.J. McLean, A.R. Spada, A.C. Ludolph, J.H. Weishaupt, and K.M. Danzer Mutual exacerbation of peroxisome proliferator-activated receptor gamma coactivator 1alpha deregulation and alpha-synuclein oligomerization Ann. Neurol. 77 2015 15 32
-
(2015)
Ann. Neurol.
, vol.77
, pp. 15-32
-
-
Eschbach, J.1
Von Einem, B.2
Muller, K.3
Bayer, H.4
Scheffold, A.5
Morrison, B.E.6
Rudolph, K.L.7
Thal, D.R.8
Witting, A.9
Weydt, P.10
Otto, M.11
Fauler, M.12
Liss, B.13
McLean, P.J.14
Spada, A.R.15
Ludolph, A.C.16
Weishaupt, J.H.17
Danzer, K.M.18
-
105
-
-
84906706633
-
Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease
-
H. Hall, S. Reyes, N. Landeck, C. Bye, G. Leanza, K. Double, L. Thompson, G. Halliday, and D. Kirik Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease Brain 137 2014 2493 2508
-
(2014)
Brain
, vol.137
, pp. 2493-2508
-
-
Hall, H.1
Reyes, S.2
Landeck, N.3
Bye, C.4
Leanza, G.5
Double, K.6
Thompson, L.7
Halliday, G.8
Kirik, D.9
-
106
-
-
0031105375
-
Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease
-
D.A. McRitchie, H.R. Cartwright, and G.M. Halliday Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease Exp. Neurol. 144 1997 202 213
-
(1997)
Exp. Neurol.
, vol.144
, pp. 202-213
-
-
McRitchie, D.A.1
Cartwright, H.R.2
Halliday, G.M.3
-
107
-
-
0022203598
-
Preservation of hypothalamic dopaminergic neurons in Parkinson's disease
-
M.M. Matzuk, and C.B. Saper Preservation of hypothalamic dopaminergic neurons in Parkinson's disease Ann. Neurol. 18 1985 552 555
-
(1985)
Ann. Neurol.
, vol.18
, pp. 552-555
-
-
Matzuk, M.M.1
Saper, C.B.2
-
108
-
-
0026712160
-
Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced Parkinsonism: Sparing of calbindin-D28k-containing cells
-
D.C. German, K.F. Manaye, P.K. Sonsalla, and B.A. Brooks Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced Parkinsonism: sparing of calbindin-D28k-containing cells Ann. N. Y. Acad. Sci. 648 1992 42 62
-
(1992)
Ann. N. Y. Acad. Sci.
, vol.648
, pp. 42-62
-
-
German, D.C.1
Manaye, K.F.2
Sonsalla, P.K.3
Brooks, B.A.4
-
109
-
-
84903998027
-
Causes and consequences of degeneration of the dorsal motor nucleus of the vagus nerve in Parkinson's disease
-
J.G. Greene Causes and consequences of degeneration of the dorsal motor nucleus of the vagus nerve in Parkinson's disease Antioxid. Redox Signal. 21 2014 649 667
-
(2014)
Antioxid. Redox Signal.
, vol.21
, pp. 649-667
-
-
Greene, J.G.1
-
110
-
-
84873427020
-
Neuronal vulnerability, pathogenesis, and Parkinson's disease
-
D. Sulzer, and D.J. Surmeier Neuronal vulnerability, pathogenesis, and Parkinson's disease Mov. Disord. 28 2013 715 724
-
(2013)
Mov. Disord.
, vol.28
, pp. 715-724
-
-
Sulzer, D.1
Surmeier, D.J.2
-
111
-
-
84858376953
-
Mitochondria: In sickness and in health
-
J. Nunnari, and A. Suomalainen Mitochondria: in sickness and in health Cell 148 2012 1145 1159
-
(2012)
Cell
, vol.148
, pp. 1145-1159
-
-
Nunnari, J.1
Suomalainen, A.2
-
112
-
-
0141676472
-
Compartmentation of glutamine, glutamate, and GABA metabolism in neurons and astrocytes: Functional implications
-
H.S. Waagepetersen, U. Sonnewald, and A. Schousboe Compartmentation of glutamine, glutamate, and GABA metabolism in neurons and astrocytes: functional implications Neuroscientist 9 2003 398 403
-
(2003)
Neuroscientist
, vol.9
, pp. 398-403
-
-
Waagepetersen, H.S.1
Sonnewald, U.2
Schousboe, A.3
-
113
-
-
0031859395
-
Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease
-
M. Gu, J.M. Cooper, J.W. Taanman, and A.H. Schapira Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease Ann. Neurol. 44 1998 177 186
-
(1998)
Ann. Neurol.
, vol.44
, pp. 177-186
-
-
Gu, M.1
Cooper, J.M.2
Taanman, J.W.3
Schapira, A.H.4
-
114
-
-
0029908226
-
Origin and functional consequences of the complex i defect in Parkinson's disease
-
R.H. Swerdlow, J.K. Parks, S.W. Miller, J.B. Tuttle, P.A. Trimmer, J.P. Sheehan, J.P. Bennett Jr., R.E. Davis, and W.D. Parker Jr. Origin and functional consequences of the complex I defect in Parkinson's disease Ann. Neurol. 40 1996 663 671
-
(1996)
Ann. Neurol.
, vol.40
, pp. 663-671
-
-
Swerdlow, R.H.1
Parks, J.K.2
Miller, S.W.3
Tuttle, J.B.4
Trimmer, P.A.5
Sheehan, J.P.6
Bennett, J.P.7
Davis, R.E.8
Parker, W.D.9
-
115
-
-
84890108110
-
Energy failure: Does it contribute to neurodegeneration?
-
D. Pathak, A. Berthet, and K. Nakamura Energy failure: does it contribute to neurodegeneration? Ann. Neurol. 74 2013 506 516
-
(2013)
Ann. Neurol.
, vol.74
, pp. 506-516
-
-
Pathak, D.1
Berthet, A.2
Nakamura, K.3
-
116
-
-
84941595622
-
The role of mitochondrially derived ATP in synaptic vesicle recycling
-
D. Pathak, L.Y. Shields, B.A. Mendelsohn, D. Haddad, W. Lin, A.A. Gerencser, H. Kim, M.D. Brand, R.H. Edwards, and K. Nakamura The role of mitochondrially derived ATP in synaptic vesicle recycling J. Biol. Chem. 290 2015 22325 22336
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 22325-22336
-
-
Pathak, D.1
Shields, L.Y.2
Mendelsohn, B.A.3
Haddad, D.4
Lin, W.5
Gerencser, A.A.6
Kim, H.7
Brand, M.D.8
Edwards, R.H.9
Nakamura, K.10
-
117
-
-
84989834247
-
Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons
-
L.Y. Shields, H. Kim, L. Zhu, D. Haddad, A. Berthet, D. Pathak, M. Lam, R. Ponnusamy, L.G. Diaz-Ramirez, T.M. Gill, H. Sesaki, L. Mucke, and K. Nakamura Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons Cell Death Dis. 6 2015 e1725
-
(2015)
Cell Death Dis.
, vol.6
, pp. e1725
-
-
Shields, L.Y.1
Kim, H.2
Zhu, L.3
Haddad, D.4
Berthet, A.5
Pathak, D.6
Lam, M.7
Ponnusamy, R.8
Diaz-Ramirez, L.G.9
Gill, T.M.10
Sesaki, H.11
Mucke, L.12
Nakamura, K.13
-
118
-
-
77952541558
-
The sites and topology of mitochondrial superoxide production
-
M.D. Brand The sites and topology of mitochondrial superoxide production Exp. Gerontol. 45 2010 466 472
-
(2010)
Exp. Gerontol.
, vol.45
, pp. 466-472
-
-
Brand, M.D.1
-
119
-
-
30044442094
-
Complex i deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage
-
C. Perier, K. Tieu, C. Guegan, C. Caspersen, V. Jackson-Lewis, V. Carelli, A. Martinuzzi, M. Hirano, S. Przedborski, and M. Vila Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage Proc. Natl. Acad. Sci. U.S.A. 102 2005 19126 19131
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 19126-19131
-
-
Perier, C.1
Tieu, K.2
Guegan, C.3
Caspersen, C.4
Jackson-Lewis, V.5
Carelli, V.6
Martinuzzi, A.7
Hirano, M.8
Przedborski, S.9
Vila, M.10
-
120
-
-
0027104639
-
Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoreductase by rotenone, piericidin A, and MPP+
-
R.R. Ramsay, and T.P. Singer Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoreductase by rotenone, piericidin A, and MPP+ Biochem. Biophys. Res. Commun. 189 1992 47 52
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.189
, pp. 47-52
-
-
Ramsay, R.R.1
Singer, T.P.2
-
121
-
-
79955954658
-
MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging
-
M.S. Lustgarten, Y.C. Jang, Y. Liu, W. Qi, Y. Qin, P.L. Dahia, Y. Shi, A. Bhattacharya, F.L. Muller, T. Shimizu, T. Shirasawa, A. Richardson, and H. Van Remmen MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging Aging Cell 10 2011 493 505
-
(2011)
Aging Cell
, vol.10
, pp. 493-505
-
-
Lustgarten, M.S.1
Jang, Y.C.2
Liu, Y.3
Qi, W.4
Qin, Y.5
Dahia, P.L.6
Shi, Y.7
Bhattacharya, A.8
Muller, F.L.9
Shimizu, T.10
Shirasawa, T.11
Richardson, A.12
Van Remmen, H.13
-
122
-
-
84884519058
-
Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex i identified by chemical screening
-
A.L. Orr, D. Ashok, M.R. Sarantos, T. Shi, R.E. Hughes, and M.D. Brand Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening Free Radical Biol Med. 65 2013 1047 1059
-
(2013)
Free Radical Biol Med.
, vol.65
, pp. 1047-1059
-
-
Orr, A.L.1
Ashok, D.2
Sarantos, M.R.3
Shi, T.4
Hughes, R.E.5
Brand, M.D.6
-
123
-
-
0028075410
-
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
-
J. Sian, D.T. Dexter, A.J. Lees, S. Daniel, Y. Agid, F. Javoy-Agid, P. Jenner, and C.D. Marsden Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia Ann. Neurol. 36 1994 348 355
-
(1994)
Ann. Neurol.
, vol.36
, pp. 348-355
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Agid, Y.5
Javoy-Agid, F.6
Jenner, P.7
Marsden, C.D.8
-
124
-
-
0024585155
-
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease
-
D.T. Dexter, C.J. Carter, F.R. Wells, F. Javoy-Agid, Y. Agid, A. Lees, P. Jenner, and C.D. Marsden Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease J. Neurochem. 52 1989 381 389
-
(1989)
J. Neurochem.
, vol.52
, pp. 381-389
-
-
Dexter, D.T.1
Carter, C.J.2
Wells, F.R.3
Javoy-Agid, F.4
Agid, Y.5
Lees, A.6
Jenner, P.7
Marsden, C.D.8
-
125
-
-
0029917194
-
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease
-
A. Yoritaka, N. Hattori, K. Uchida, M. Tanaka, E.R. Stadtman, and Y. Mizuno Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease Proc. Natl. Acad. Sci. U.S.A. 93 1996 2696 2701
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 2696-2701
-
-
Yoritaka, A.1
Hattori, N.2
Uchida, K.3
Tanaka, M.4
Stadtman, E.R.5
Mizuno, Y.6
-
126
-
-
0030805622
-
A generalized increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
-
Z.I. Alam, S.E. Daniel, A.J. Lees, D.C. Marsden, P. Jenner, and B. Halliwell A generalized increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease J. Neurochem. 69 1997 1326 1329
-
(1997)
J. Neurochem.
, vol.69
, pp. 1326-1329
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, D.C.4
Jenner, P.5
Halliwell, B.6
-
127
-
-
0030878073
-
Oxidative DNA damage in the Parkinsonian brain: An apparent selective increase in 8-hudroxyguanine levels in substantia nigra
-
Z.I. Alam, A. Jenner, S.E. Daniel, A.J. Lees, N. Cairns, C.D. Marsden, P. Jenner, and B. Halliwell Oxidative DNA damage in the Parkinsonian brain: an apparent selective increase in 8-hudroxyguanine levels in substantia nigra J. Neurochem. 69 1997 1196 1203
-
(1997)
J. Neurochem.
, vol.69
, pp. 1196-1203
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
Jenner, P.7
Halliwell, B.8
-
128
-
-
84901321275
-
Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease
-
G.S. Gaki, and A.G. Papavassiliou Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease Neuromol. Med. 16 2014 217 230
-
(2014)
Neuromol. Med.
, vol.16
, pp. 217-230
-
-
Gaki, G.S.1
Papavassiliou, A.G.2
-
129
-
-
57649155208
-
Oxidative stress in Parkinson's disease: A mechanism of pathogenic and therapeutic significance
-
C. Zhou, Y. Huang, and S. Przedborski Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance Ann. N. Y. Acad. Sci. 1147 2008 93 104
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1147
, pp. 93-104
-
-
Zhou, C.1
Huang, Y.2
Przedborski, S.3
-
130
-
-
0031263929
-
Neurotoxicity of endogenous cysteinylcatechols
-
T.J. Montine, M.J. Picklo, V. Amarnath, W.O. Whetsell Jr., and D.G. Graham Neurotoxicity of endogenous cysteinylcatechols Exp. Neurol. 148 1997 26 33
-
(1997)
Exp. Neurol.
, vol.148
, pp. 26-33
-
-
Montine, T.J.1
Picklo, M.J.2
Amarnath, V.3
Whetsell, W.O.4
Graham, D.G.5
-
131
-
-
0032842038
-
Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: Implications for Parkinson's disease
-
S.B. Berman, and T.G. Hastings Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease J. Neurochem. 73 1999 1127 1137
-
(1999)
J. Neurochem.
, vol.73
, pp. 1127-1137
-
-
Berman, S.B.1
Hastings, T.G.2
-
132
-
-
34547467082
-
Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration
-
W.M. Caudle, J.R. Richardson, M.Z. Wang, T.N. Taylor, T.S. Guillot, A.L. McCormack, R.E. Colebrooke, D.A. Di Monte, P.C. Emson, and G.W. Miller Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration J. Neurosci. 27 2007 8138 8148
-
(2007)
J. Neurosci.
, vol.27
, pp. 8138-8148
-
-
Caudle, W.M.1
Richardson, J.R.2
Wang, M.Z.3
Taylor, T.N.4
Guillot, T.S.5
McCormack, A.L.6
Colebrooke, R.E.7
Di Monte, D.A.8
Emson, P.C.9
Miller, G.W.10
-
133
-
-
65249180086
-
Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons
-
E.V. Mosharov, K.E. Larsen, E. Kanter, K.A. Phillips, K. Wilson, Y. Schmitz, D.E. Krantz, K. Kobayashi, R.H. Edwards, and D. Sulzer Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons Neuron 62 2009 218 229
-
(2009)
Neuron
, vol.62
, pp. 218-229
-
-
Mosharov, E.V.1
Larsen, K.E.2
Kanter, E.3
Phillips, K.A.4
Wilson, K.5
Schmitz, Y.6
Krantz, D.E.7
Kobayashi, K.8
Edwards, R.H.9
Sulzer, D.10
-
134
-
-
0035860682
-
Tetrahydrobiopterin scavenges superoxide in dopaminergic neurons
-
K. Nakamura, V.P. Bindokas, D. Kowlessur, M. Elas, S. Milstien, J.D. Marks, H.J. Halpern, and U.J. Kang Tetrahydrobiopterin scavenges superoxide in dopaminergic neurons J. Biol. Chem. 276 2001 34402 34407
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34402-34407
-
-
Nakamura, K.1
Bindokas, V.P.2
Kowlessur, D.3
Elas, M.4
Milstien, S.5
Marks, J.D.6
Halpern, H.J.7
Kang, U.J.8
-
135
-
-
0034123981
-
Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin
-
K. Nakamura, D.A. Wright, T. Wiatr, D. Kowlessur, S. Milstien, X.G. Lei, and U.J. Kang Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin J. Neurochem. 74 2000 2305 2315
-
(2000)
J. Neurochem.
, vol.74
, pp. 2305-2315
-
-
Nakamura, K.1
Wright, D.A.2
Wiatr, T.3
Kowlessur, D.4
Milstien, S.5
Lei, X.G.6
Kang, U.J.7
-
136
-
-
84878892468
-
Calcium entry and alpha-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons
-
D.I. Dryanovski, J.N. Guzman, Z. Xie, D.J. Galteri, L.A. Volpicelli-Daley, V.M. Lee, R.J. Miller, P.T. Schumacker, and D.J. Surmeier Calcium entry and alpha-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons J. Neurosci. 33 2013 10154 10164
-
(2013)
J. Neurosci.
, vol.33
, pp. 10154-10164
-
-
Dryanovski, D.I.1
Guzman, J.N.2
Xie, Z.3
Galteri, D.J.4
Volpicelli-Daley, L.A.5
Lee, V.M.6
Miller, R.J.7
Schumacker, P.T.8
Surmeier, D.J.9
-
137
-
-
0026637866
-
Why are nigral catecholaminergic neurons more vulnerable than other cells in Parkinson's disease
-
E.C. Hirsch Why are nigral catecholaminergic neurons more vulnerable than other cells in Parkinson's disease Ann. Neurol. 32 1992 S88 S93
-
(1992)
Ann. Neurol.
, vol.32
, pp. S88-S93
-
-
Hirsch, E.C.1
-
138
-
-
67649800742
-
NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation
-
A.M. Brennan, S.W. Suh, S.J. Won, P. Narasimhan, T.M. Kauppinen, H. Lee, Y. Edling, P.H. Chan, and R.A. Swanson NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation Nat. Neurosci. 12 2009 857 863
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 857-863
-
-
Brennan, A.M.1
Suh, S.W.2
Won, S.J.3
Narasimhan, P.4
Kauppinen, T.M.5
Lee, H.6
Edling, Y.7
Chan, P.H.8
Swanson, R.A.9
-
139
-
-
84921875050
-
Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanthine oxidase activation
-
S. Kovac, A.M. Domijan, M.C. Walker, and A.Y. Abramov Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanthine oxidase activation Cell Death Dis. 5 2014 e1442
-
(2014)
Cell Death Dis.
, vol.5
, pp. e1442
-
-
Kovac, S.1
Domijan, A.M.2
Walker, M.C.3
Abramov, A.Y.4
-
140
-
-
1642540210
-
The mitochondrial calcium uniporter is a highly selective ion channel
-
Y. Kirichok, G. Krapivinsky, and D.E. Clapham The mitochondrial calcium uniporter is a highly selective ion channel Nature 427 2004 360 364
-
(2004)
Nature
, vol.427
, pp. 360-364
-
-
Kirichok, Y.1
Krapivinsky, G.2
Clapham, D.E.3
-
141
-
-
80051946060
-
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
-
J.M. Baughman, F. Perocchi, H.S. Girgis, M. Plovanich, C.A. Belcher-Timme, Y. Sancak, X.R. Bao, L. Strittmatter, O. Goldberger, R.L. Bogorad, V. Koteliansky, and V.K. Mootha Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter Nature 476 2011 341 345
-
(2011)
Nature
, vol.476
, pp. 341-345
-
-
Baughman, J.M.1
Perocchi, F.2
Girgis, H.S.3
Plovanich, M.4
Belcher-Timme, C.A.5
Sancak, Y.6
Bao, X.R.7
Strittmatter, L.8
Goldberger, O.9
Bogorad, R.L.10
Koteliansky, V.11
Mootha, V.K.12
-
144
-
-
0018269944
-
The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria
-
D.G. Nicholls The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria Biochem. J. 176 1978 463 474
-
(1978)
Biochem. J.
, vol.176
, pp. 463-474
-
-
Nicholls, D.G.1
-
145
-
-
0021990010
-
Regulation of oxidative phosphorylation in mitochondria by external free Ca2+ concentrations
-
R. Moreno-Sanchez Regulation of oxidative phosphorylation in mitochondria by external free Ca2+ concentrations J. Biol. Chem. 260 1985 4028 4034
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 4028-4034
-
-
Moreno-Sanchez, R.1
-
146
-
-
84938920704
-
The regulation of neuronal mitochondrial metabolism by calcium
-
I. Llorente-Folch, C.B. Rueda, B. Pardo, G. Szabadkai, M.R. Duchen, and J. Satrustegui The regulation of neuronal mitochondrial metabolism by calcium J. Physiol. 593 2015 3447 3462
-
(2015)
J. Physiol.
, vol.593
, pp. 3447-3462
-
-
Llorente-Folch, I.1
Rueda, C.B.2
Pardo, B.3
Szabadkai, G.4
Duchen, M.R.5
Satrustegui, J.6
-
147
-
-
84859560882
-
Role of mitochondrial Ca2+ in the regulation of cellular energetics
-
B. Glancy, and R.S. Balaban Role of mitochondrial Ca2+ in the regulation of cellular energetics Biochemistry 51 2012 2959 2973
-
(2012)
Biochemistry
, vol.51
, pp. 2959-2973
-
-
Glancy, B.1
Balaban, R.S.2
-
148
-
-
0034052542
-
Ca(2+) activation of heart mitochondrial oxidative phosphorylation: Role of the F(0)/F(1)-ATPase
-
P.R. Territo, V.K. Mootha, S.A. French, and R.S. Balaban Ca(2+) activation of heart mitochondrial oxidative phosphorylation: role of the F(0)/F(1)-ATPase Am. J. Physiol. Cell Physiol. 278 2000 C423 C435
-
(2000)
Am. J. Physiol. Cell Physiol.
, vol.278
, pp. C423-C435
-
-
Territo, P.R.1
Mootha, V.K.2
French, S.A.3
Balaban, R.S.4
-
149
-
-
68649090226
-
Regulation of mitochondrial dehydrogenases by calcium ions
-
R.M. Denton Regulation of mitochondrial dehydrogenases by calcium ions Biochim. Biophys. Acta 1787 2009 1309 1316
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 1309-1316
-
-
Denton, R.M.1
-
150
-
-
84876214388
-
Calcium, bioenergetics, and neuronal vulnerability in Parkinson's disease
-
D.J. Surmeier, and P.T. Schumacker Calcium, bioenergetics, and neuronal vulnerability in Parkinson's disease J. Biol. Chem. 288 2013 10736 10741
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 10736-10741
-
-
Surmeier, D.J.1
Schumacker, P.T.2
-
151
-
-
84882980197
-
Calcium-regulation of mitochondrial respiration maintains ATP homeostasis and requires ARALAR/AGC1-malate aspartate shuttle in intact cortical neurons
-
13957-71, 13971a
-
I. Llorente-Folch, C.B. Rueda, I. Amigo, A. del Arco, T. Saheki, B. Pardo, and J. Satrustegui Calcium-regulation of mitochondrial respiration maintains ATP homeostasis and requires ARALAR/AGC1-malate aspartate shuttle in intact cortical neurons J. Neurosci. 33 2013 13957-71, 13971a
-
(2013)
J. Neurosci.
, vol.33
-
-
Llorente-Folch, I.1
Rueda, C.B.2
Amigo, I.3
Del Arco, A.4
Saheki, T.5
Pardo, B.6
Satrustegui, J.7
-
152
-
-
0030601734
-
Midbrain dopaminergic neurons in the mouse: Co-localization with calbindin-D28K and calretinin
-
C.L. Liang, C.M. Sinton, and D.C. German Midbrain dopaminergic neurons in the mouse: co-localization with calbindin-D28K and calretinin Neuroscience 75 1996 523 533
-
(1996)
Neuroscience
, vol.75
, pp. 523-533
-
-
Liang, C.L.1
Sinton, C.M.2
German, D.C.3
-
153
-
-
0037418843
-
BAX and BAK regulation of endoplasmic reticulum Ca2+: A control point for apoptosis
-
L. Scorrano, S.A. Oakes, J.T. Opferman, E.H. Cheng, M.D. Sorcinelli, T. Pozzan, and S.J. Korsmeyer BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis Science 300 2003 135 139
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
Oakes, S.A.2
Opferman, J.T.3
Cheng, E.H.4
Sorcinelli, M.D.5
Pozzan, T.6
Korsmeyer, S.J.7
-
154
-
-
67649342203
-
Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: Relevance to Parkinson's disease
-
D.M. Arduino, A.R. Esteves, S.M. Cardoso, and C.R. Oliveira Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease Neurochem. Int. 55 2009 341 348
-
(2009)
Neurochem. Int.
, vol.55
, pp. 341-348
-
-
Arduino, D.M.1
Esteves, A.R.2
Cardoso, S.M.3
Oliveira, C.R.4
-
156
-
-
84863218983
-
2+ and apoptosis
-
2+ and apoptosis Cell Calcium 52 2012 36 43
-
(2012)
Cell Calcium
, vol.52
, pp. 36-43
-
-
Giorgi, C.1
Baldassari, F.2
Bononi, A.3
Bonora, M.4
De Marchi, E.5
Marchi, S.6
Missiroli, S.7
Patergnani, S.8
Rimessi, A.9
Suski, J.M.10
Wieckowski, M.R.11
Pinton, P.12
-
157
-
-
61649088435
-
PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death
-
S. Gandhi, A. Wood-Kaczmar, Z. Yao, H. Plun-Favreau, E. Deas, K. Klupsch, J. Downward, D.S. Latchman, S.J. Tabrizi, N.W. Wood, M.R. Duchen, and A.Y. Abramov PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death Mol. Cell 33 2009 627 638
-
(2009)
Mol. Cell
, vol.33
, pp. 627-638
-
-
Gandhi, S.1
Wood-Kaczmar, A.2
Yao, Z.3
Plun-Favreau, H.4
Deas, E.5
Klupsch, K.6
Downward, J.7
Latchman, D.S.8
Tabrizi, S.J.9
Wood, N.W.10
Duchen, M.R.11
Abramov, A.Y.12
-
158
-
-
0032511112
-
Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses
-
R. Rizzuto, P. Pinton, W. Carrington, F.S. Fay, K.E. Fogarty, L.M. Lifshitz, R.A. Tuft, and T. Pozzan Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses Science 280 1998 1763 1766
-
(1998)
Science
, vol.280
, pp. 1763-1766
-
-
Rizzuto, R.1
Pinton, P.2
Carrington, W.3
Fay, F.S.4
Fogarty, K.E.5
Lifshitz, L.M.6
Tuft, R.A.7
Pozzan, T.8
-
159
-
-
84938217139
-
ER-to-mitochondria miscommunication and metabolic diseases
-
C. Lopez-Crisosto, R. Bravo-Sagua, M. Rodriguez-Pena, C. Mera, P.F. Castro, A.F. Quest, B.A. Rothermel, M. Cifuentes, and S. Lavandero ER-to-mitochondria miscommunication and metabolic diseases Biochim. Biophys. Acta 1852 2015 2096 2105
-
(2015)
Biochim. Biophys. Acta
, vol.1852
, pp. 2096-2105
-
-
Lopez-Crisosto, C.1
Bravo-Sagua, R.2
Rodriguez-Pena, M.3
Mera, C.4
Castro, P.F.5
Quest, A.F.6
Rothermel, B.A.7
Cifuentes, M.8
Lavandero, S.9
-
160
-
-
77955041880
-
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria
-
C. Cardenas, R.A. Miller, I. Smith, T. Bui, J. Molgo, M. Muller, H. Vais, K.H. Cheung, J. Yang, I. Parker, C.B. Thompson, M.J. Birnbaum, K.R. Hallows, and J.K. Foskett Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria Cell 142 2010 270 283
-
(2010)
Cell
, vol.142
, pp. 270-283
-
-
Cardenas, C.1
Miller, R.A.2
Smith, I.3
Bui, T.4
Molgo, J.5
Muller, M.6
Vais, H.7
Cheung, K.H.8
Yang, J.9
Parker, I.10
Thompson, C.B.11
Birnbaum, M.J.12
Hallows, K.R.13
Foskett, J.K.14
-
161
-
-
84891410019
-
Alpha-Synuclein is localized to mitochondria-associated ER membranes
-
C. Guardia-Laguarta, E. Area-Gomez, C. Rub, Y. Liu, J. Magrane, D. Becker, W. Voos, E.A. Schon, and S. Przedborski Alpha-Synuclein is localized to mitochondria-associated ER membranes J. Neurosci. 34 2014 249 259
-
(2014)
J. Neurosci.
, vol.34
, pp. 249-259
-
-
Guardia-Laguarta, C.1
Area-Gomez, E.2
Rub, C.3
Liu, Y.4
Magrane, J.5
Becker, D.6
Voos, W.7
Schon, E.A.8
Przedborski, S.9
-
162
-
-
84876098997
-
The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering
-
D. Ottolini, T. Cali, A. Negro, and M. Brini The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering Hum. Mol. Genet. 22 2013 2152 2168
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 2152-2168
-
-
Ottolini, D.1
Cali, T.2
Negro, A.3
Brini, M.4
-
163
-
-
84873254580
-
Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics
-
T. Cali, D. Ottolini, A. Negro, and M. Brini Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics Biochim. Biophys. Acta 1832 2013 495 508
-
(2013)
Biochim. Biophys. Acta
, vol.1832
, pp. 495-508
-
-
Cali, T.1
Ottolini, D.2
Negro, A.3
Brini, M.4
-
164
-
-
84938717912
-
Glitazone treatment and incidence of Parkinson's disease among people with diabetes: A retrospective cohort study
-
R. Brauer, K. Bhaskaran, N. Chaturvedi, D.T. Dexter, L. Smeeth, and I. Douglas Glitazone treatment and incidence of Parkinson's disease among people with diabetes: a retrospective cohort study PLoS Med. 12 2015 e1001854
-
(2015)
PLoS Med.
, vol.12
, pp. e1001854
-
-
Brauer, R.1
Bhaskaran, K.2
Chaturvedi, N.3
Dexter, D.T.4
Smeeth, L.5
Douglas, I.6
-
165
-
-
84929273586
-
Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines
-
A. Shaltouki, R. Sivapatham, Y. Pei, A.A. Gerencser, O. Momcilovic, M.S. Rao, and X. Zeng Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines Stem Cell Rep. 4 2015 847 859
-
(2015)
Stem Cell Rep.
, vol.4
, pp. 847-859
-
-
Shaltouki, A.1
Sivapatham, R.2
Pei, Y.3
Gerencser, A.A.4
Momcilovic, O.5
Rao, M.S.6
Zeng, X.7
-
166
-
-
49649097747
-
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
C.A. Gautier, T. Kitada, and J. Shen Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress Proc. Natl. Acad. Sci. U.S.A. 105 2008 11364 11369
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
167
-
-
66749163493
-
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration
-
S. Gispert, F. Ricciardi, A. Kurz, M. Azizov, H.H. Hoepken, D. Becker, W. Voos, K. Leuner, W.E. Muller, A.P. Kudin, W.S. Kunz, A. Zimmermann, J. Roeper, D. Wenzel, M. Jendrach, M. Garcia-Arencibia, J. Fernandez-Ruiz, L. Huber, H. Rohrer, M. Barrera, A.S. Reichert, U. Rub, A. Chen, R.L. Nussbaum, and G. Auburger Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration PLoS One 4 2009 e5777
-
(2009)
PLoS One
, vol.4
, pp. e5777
-
-
Gispert, S.1
Ricciardi, F.2
Kurz, A.3
Azizov, M.4
Hoepken, H.H.5
Becker, D.6
Voos, W.7
Leuner, K.8
Muller, W.E.9
Kudin, A.P.10
Kunz, W.S.11
Zimmermann, A.12
Roeper, J.13
Wenzel, D.14
Jendrach, M.15
Garcia-Arencibia, M.16
Fernandez-Ruiz, J.17
Huber, L.18
Rohrer, H.19
Barrera, M.20
Reichert, A.S.21
Rub, U.22
Chen, A.23
Nussbaum, R.L.24
Auburger, G.25
more..
-
168
-
-
84937438976
-
Endogenous Parkin preserves dopaminergic substantia nigral neurons following mitochondrial DNA mutagenic stress
-
A.M. Pickrell, C.H. Huang, S.R. Kennedy, A. Ordureau, D.P. Sideris, J.G. Hoekstra, J.W. Harper, and R.J. Youle Endogenous Parkin preserves dopaminergic substantia nigral neurons following mitochondrial DNA mutagenic stress Neuron 87 2015 371 381
-
(2015)
Neuron
, vol.87
, pp. 371-381
-
-
Pickrell, A.M.1
Huang, C.H.2
Kennedy, S.R.3
Ordureau, A.4
Sideris, D.P.5
Hoekstra, J.G.6
Harper, J.W.7
Youle, R.J.8
-
169
-
-
33846460819
-
Mitochondria mass is low in mouse substantia nigra dopamine neurons: Implications for Parkinson's disease
-
C.L. Liang, T.T. Wang, K. Luby-Phelps, and D.C. German Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease Exp. Neurol. 203 2007 370 380
-
(2007)
Exp. Neurol.
, vol.203
, pp. 370-380
-
-
Liang, C.L.1
Wang, T.T.2
Luby-Phelps, K.3
German, D.C.4
-
170
-
-
0014665731
-
The turnover of the protein components of the inner and outer membrane fractions of rat liver mitochondria
-
D.S. Beattie The turnover of the protein components of the inner and outer membrane fractions of rat liver mitochondria Biochem. Biophys. Res. Commun. 35 1969 721 727
-
(1969)
Biochem. Biophys. Res. Commun.
, vol.35
, pp. 721-727
-
-
Beattie, D.S.1
-
171
-
-
84876213313
-
The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
-
E.S. Vincow, G. Merrihew, R.E. Thomas, N.J. Shulman, R.P. Beyer, M.J. MacCoss, and L.J. Pallanck The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo Proc. Natl. Acad. Sci. U.S.A. 110 2013 6400 6405
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 6400-6405
-
-
Vincow, E.S.1
Merrihew, G.2
Thomas, R.E.3
Shulman, N.J.4
Beyer, R.P.5
MacCoss, M.J.6
Pallanck, L.J.7
-
172
-
-
84908085343
-
A new pathway for mitochondrial quality control: Mitochondrial-derived vesicles
-
A. Sugiura, G.L. McLelland, E.A. Fon, and H.M. McBride A new pathway for mitochondrial quality control: mitochondrial-derived vesicles EMBO J. 33 2014 2142 2156
-
(2014)
EMBO J.
, vol.33
, pp. 2142-2156
-
-
Sugiura, A.1
McLelland, G.L.2
Fon, E.A.3
McBride, H.M.4
-
173
-
-
84920426451
-
Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations
-
V.K. Godena, N. Brookes-Hocking, A. Moller, G. Shaw, M. Oswald, R.M. Sancho, C.C. Miller, A.J. Whitworth, and K.J. De Vos Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations Nat Commun. 5 2014 5245
-
(2014)
Nat Commun.
, vol.5
, pp. 5245
-
-
Godena, V.K.1
Brookes-Hocking, N.2
Moller, A.3
Shaw, G.4
Oswald, M.5
Sancho, R.M.6
Miller, C.C.7
Whitworth, A.J.8
De Vos, K.J.9
-
174
-
-
84893521264
-
Human A53T alpha-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neurons
-
L. Li, S. Nadanaciva, Z. Berger, W. Shen, K. Paumier, J. Schwartz, K. Mou, P. Loos, A.J. Milici, J. Dunlop, and W.D. Hirst Human A53T alpha-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neurons PLoS One 8 2013 e85815
-
(2013)
PLoS One
, vol.8
, pp. e85815
-
-
Li, L.1
Nadanaciva, S.2
Berger, Z.3
Shen, W.4
Paumier, K.5
Schwartz, J.6
Mou, K.7
Loos, P.8
Milici, A.J.9
Dunlop, J.10
Hirst, W.D.11
-
175
-
-
84923355252
-
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
-
P.M. Rappold, M. Cui, J.C. Grima, R.Z. Fan, K.L. de Mesy-Bentley, L. Chen, X. Zhuang, W.J. Bowers, and K. Tieu Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo Nat. Commun. 5 2014 5244
-
(2014)
Nat. Commun.
, vol.5
, pp. 5244
-
-
Rappold, P.M.1
Cui, M.2
Grima, J.C.3
Fan, R.Z.4
De Mesy-Bentley, K.L.5
Chen, L.6
Zhuang, X.7
Bowers, W.J.8
Tieu, K.9
-
176
-
-
84881611195
-
Motile axonal mitochondria contribute to the variability of presynaptic strength
-
T. Sun, H. Qiao, P.Y. Pan, Y. Chen, and Z.H. Sheng Motile axonal mitochondria contribute to the variability of presynaptic strength Cell Rep. 4 2013 413 419
-
(2013)
Cell Rep.
, vol.4
, pp. 413-419
-
-
Sun, T.1
Qiao, H.2
Pan, P.Y.3
Chen, Y.4
Sheng, Z.H.5
-
177
-
-
35448960851
-
Functions and dysfunctions of mitochondrial dynamics
-
S.A. Detmer, and D.C. Chan Functions and dysfunctions of mitochondrial dynamics Nat. Rev. Mol. Cell Biol. 8 2007 870 879
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 870-879
-
-
Detmer, S.A.1
Chan, D.C.2
-
178
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
A. Tanaka, M.M. Cleland, S. Xu, D.P. Narendra, D.F. Suen, M. Karbowski, and R.J. Youle Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin J. Cell Biol. 191 2010 1367 1380
-
(2010)
J. Cell Biol.
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
179
-
-
84908079648
-
Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons
-
A. Berthet, E.B. Margolis, J. Zhang, I. Hsieh, T.S. Hnasko, J. Ahmad, R.H. Edwards, H. Sesaki, E.J. Huang, and K. Nakamura Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons J. Neurosci. 34 2014 14304 14317
-
(2014)
J. Neurosci.
, vol.34
, pp. 14304-14317
-
-
Berthet, A.1
Margolis, E.B.2
Zhang, J.3
Hsieh, I.4
Hnasko, T.S.5
Ahmad, J.6
Edwards, R.H.7
Sesaki, H.8
Huang, E.J.9
Nakamura, K.10
-
180
-
-
84868127674
-
Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit
-
A.H. Pham, S. Meng, Q.N. Chu, and D.C. Chan Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit Hum. Mol. Genet. 21 2012 4817 4826
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 4817-4826
-
-
Pham, A.H.1
Meng, S.2
Chu, Q.N.3
Chan, D.C.4
-
181
-
-
84933178508
-
Syndromic Parkinsonism and dementia associated with OPA1 missense mutations
-
V. Carelli, O. Musumeci, L. Caporali, C. Zanna, C. La Morgia, V. Del Dotto, A.M. Porcelli, M. Rugolo, M.L. Valentino, L. Iommarini, A. Maresca, P. Barboni, M. Carbonelli, C. Trombetta, E.M. Valente, S. Patergnani, C. Giorgi, P. Pinton, G. Rizzo, C. Tonon, R. Lodi, P. Avoni, R. Liguori, A. Baruzzi, A. Toscano, and M. Zeviani Syndromic Parkinsonism and dementia associated with OPA1 missense mutations Ann. Neurol. 78 2015 21 38
-
(2015)
Ann. Neurol.
, vol.78
, pp. 21-38
-
-
Carelli, V.1
Musumeci, O.2
Caporali, L.3
Zanna, C.4
La Morgia, C.5
Del Dotto, V.6
Porcelli, A.M.7
Rugolo, M.8
Valentino, M.L.9
Iommarini, L.10
Maresca, A.11
Barboni, P.12
Carbonelli, M.13
Trombetta, C.14
Valente, E.M.15
Patergnani, S.16
Giorgi, C.17
Pinton, P.18
Rizzo, G.19
Tonon, C.20
Lodi, R.21
Avoni, P.22
Liguori, R.23
Baruzzi, A.24
Toscano, A.25
Zeviani, M.26
more..
-
182
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
E. Ziviani, R.N. Tao, and A.J. Whitworth Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin Proc. Natl. Acad. Sci. U.S.A. 107 2010 5018 5023
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
184
-
-
84911494334
-
Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export
-
H.J. Cho, J. Yu, C. Xie, P. Rudrabhatla, X. Chen, J. Wu, L. Parisiadou, G. Liu, L. Sun, B. Ma, J. Ding, Z. Liu, and H. Cai Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export EMBO J. 33 2014 2314 2331
-
(2014)
EMBO J.
, vol.33
, pp. 2314-2331
-
-
Cho, H.J.1
Yu, J.2
Xie, C.3
Rudrabhatla, P.4
Chen, X.5
Wu, J.6
Parisiadou, L.7
Liu, G.8
Sun, L.9
Ma, B.10
Ding, J.11
Liu, Z.12
Cai, H.13
-
185
-
-
4344659685
-
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
-
A.M. Cuervo, L. Stefanis, R. Fredenburg, P.T. Lansbury, and D. Sulzer Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy Science 305 2004 1292 1295
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
186
-
-
0034784359
-
An energy budget for signaling in the grey matter of the brain
-
D. Attwell, and S.B. Laughlin An energy budget for signaling in the grey matter of the brain J. Cereb. Blood Flow Metab. 21 2001 1133 1145
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 1133-1145
-
-
Attwell, D.1
Laughlin, S.B.2
-
187
-
-
34347359673
-
'Rejuvenation' protects neurons in mouse models of Parkinson's disease
-
C.S. Chan, J.N. Guzman, E. Ilijic, J.N. Mercer, C. Rick, T. Tkatch, G.E. Meredith, and D.J. Surmeier 'Rejuvenation' protects neurons in mouse models of Parkinson's disease Nature 447 2007 1081 1086
-
(2007)
Nature
, vol.447
, pp. 1081-1086
-
-
Chan, C.S.1
Guzman, J.N.2
Ilijic, E.3
Mercer, J.N.4
Rick, C.5
Tkatch, T.6
Meredith, G.E.7
Surmeier, D.J.8
-
188
-
-
28044469874
-
K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons
-
B. Liss, O. Haeckel, J. Wildmann, T. Miki, S. Seino, and J. Roeper K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons Nat. Neurosci. 8 2005 1742 1751
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1742-1751
-
-
Liss, B.1
Haeckel, O.2
Wildmann, J.3
Miki, T.4
Seino, S.5
Roeper, J.6
-
189
-
-
84866113698
-
K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration
-
J. Schiemann, F. Schlaudraff, V. Klose, M. Bingmer, S. Seino, P.J. Magill, K.A. Zaghloul, G. Schneider, B. Liss, and J. Roeper K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration Nat. Neurosci. 15 2012 1272 1280
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 1272-1280
-
-
Schiemann, J.1
Schlaudraff, F.2
Klose, V.3
Bingmer, M.4
Seino, S.5
Magill, P.J.6
Zaghloul, K.A.7
Schneider, G.8
Liss, B.9
Roeper, J.10
-
190
-
-
0021235482
-
Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical Parkinsonism
-
M.J. Zigmond, A.L. Acheson, M.K. Stachowiak, and E.M. Stricker Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical Parkinsonism Arch. Neurol. 41 1984 856 861
-
(1984)
Arch. Neurol.
, vol.41
, pp. 856-861
-
-
Zigmond, M.J.1
Acheson, A.L.2
Stachowiak, M.K.3
Stricker, E.M.4
-
191
-
-
0023214339
-
Increased dopamine efflux from striatal slices during development and after nigrostriatal bundle damage
-
M.K. Stachowiak, R.W. Keller Jr., E.M. Stricker, and M.J. Zigmond Increased dopamine efflux from striatal slices during development and after nigrostriatal bundle damage J. Neurosci. 7 1987 1648 1654
-
(1987)
J. Neurosci.
, vol.7
, pp. 1648-1654
-
-
Stachowiak, M.K.1
Keller, R.W.2
Stricker, E.M.3
Zigmond, M.J.4
-
192
-
-
0023948634
-
Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: A microdialysis study in freely moving rats
-
T.E. Robinson, and I.Q. Whishaw Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats Brain Res. 450 1988 209 224
-
(1988)
Brain Res.
, vol.450
, pp. 209-224
-
-
Robinson, T.E.1
Whishaw, I.Q.2
-
193
-
-
0025077453
-
The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons
-
J.R. Hollerman, and A.A. Grace The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons Brain Res. 533 1990 203 212
-
(1990)
Brain Res.
, vol.533
, pp. 203-212
-
-
Hollerman, J.R.1
Grace, A.A.2
-
194
-
-
78650877121
-
Hyperexcitable substantia nigra dopamine neurons in PINK1- and HtrA2/Omi-deficient mice
-
M.W. Bishop, S. Chakraborty, G.A. Matthews, A. Dougalis, N.W. Wood, R. Festenstein, and M.A. Ungless Hyperexcitable substantia nigra dopamine neurons in PINK1- and HtrA2/Omi-deficient mice J. Neurophysiol. 104 2010 3009 3020
-
(2010)
J. Neurophysiol.
, vol.104
, pp. 3009-3020
-
-
Bishop, M.W.1
Chakraborty, S.2
Matthews, G.A.3
Dougalis, A.4
Wood, N.W.5
Festenstein, R.6
Ungless, M.A.7
-
195
-
-
84923426070
-
Mutant alpha-synuclein enhances firing frequencies in dopamine substantia nigra neurons by oxidative impairment of A-type potassium channels
-
M. Subramaniam, D. Althof, S. Gispert, J. Schwenk, G. Auburger, A. Kulik, B. Fakler, and J. Roeper Mutant alpha-synuclein enhances firing frequencies in dopamine substantia nigra neurons by oxidative impairment of A-type potassium channels J. Neurosci. 34 2014 13586 13599
-
(2014)
J. Neurosci.
, vol.34
, pp. 13586-13599
-
-
Subramaniam, M.1
Althof, D.2
Gispert, S.3
Schwenk, J.4
Auburger, G.5
Kulik, A.6
Fakler, B.7
Roeper, J.8
-
196
-
-
70350289959
-
Endogenous calcium buffering capacity of substantia nigral dopamine neurons
-
R.C. Foehring, X.F. Zhang, J.C. Lee, and J.C. Callaway Endogenous calcium buffering capacity of substantia nigral dopamine neurons J. Neurophysiol. 102 2009 2326 2333
-
(2009)
J. Neurophysiol.
, vol.102
, pp. 2326-2333
-
-
Foehring, R.C.1
Zhang, X.F.2
Lee, J.C.3
Callaway, J.C.4
-
197
-
-
58849089960
-
Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum
-
W. Matsuda, T. Furuta, K.C. Nakamura, H. Hioki, F. Fujiyama, R. Arai, and T. Kaneko Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum J. Neurosci. 29 2009 444 453
-
(2009)
J. Neurosci.
, vol.29
, pp. 444-453
-
-
Matsuda, W.1
Furuta, T.2
Nakamura, K.C.3
Hioki, H.4
Fujiyama, F.5
Arai, R.6
Kaneko, T.7
-
198
-
-
84867745060
-
Living on the edge with too many mouths to feed: Why dopamine neurons die
-
J.P. Bolam, and E.K. Pissadaki Living on the edge with too many mouths to feed: why dopamine neurons die Mov. Disord. 27 2012 1478 1483
-
(2012)
Mov. Disord.
, vol.27
, pp. 1478-1483
-
-
Bolam, J.P.1
Pissadaki, E.K.2
-
199
-
-
84855962723
-
The energetics of CNS white matter
-
J.J. Harris, and D. Attwell The energetics of CNS white matter J. Neurosci. 32 2012 356 371
-
(2012)
J. Neurosci.
, vol.32
, pp. 356-371
-
-
Harris, J.J.1
Attwell, D.2
-
200
-
-
0346850964
-
Poor and protracted myelination as a contributory factor to neurodegenerative disorders
-
H. Braak, and K. Del Tredici Poor and protracted myelination as a contributory factor to neurodegenerative disorders Neurobiol. Aging 25 2004 19 23
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 19-23
-
-
Braak, H.1
Del Tredici, K.2
-
201
-
-
80055074305
-
Unmyelinated axons are more vulnerable to degeneration than myelinated axons of the cardiac nerve in Parkinson's disease
-
S. Orimo, T. Uchihara, T. Kanazawa, Y. Itoh, K. Wakabayashi, A. Kakita, and H. Takahashi Unmyelinated axons are more vulnerable to degeneration than myelinated axons of the cardiac nerve in Parkinson's disease Neuropathol. Appl. Neurobiol. 37 2011 791 802
-
(2011)
Neuropathol. Appl. Neurobiol.
, vol.37
, pp. 791-802
-
-
Orimo, S.1
Uchihara, T.2
Kanazawa, T.3
Itoh, Y.4
Wakabayashi, K.5
Kakita, A.6
Takahashi, H.7
-
203
-
-
84861429431
-
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity
-
U. Funfschilling, L.M. Supplie, D. Mahad, S. Boretius, A.S. Saab, J. Edgar, B.G. Brinkmann, C.M. Kassmann, I.D. Tzvetanova, W. Mobius, F. Diaz, D. Meijer, U. Suter, B. Hamprecht, M.W. Sereda, C.T. Moraes, J. Frahm, S. Goebbels, and K.A. Nave Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity Nature 485 2012 517 521
-
(2012)
Nature
, vol.485
, pp. 517-521
-
-
Funfschilling, U.1
Supplie, L.M.2
Mahad, D.3
Boretius, S.4
Saab, A.S.5
Edgar, J.6
Brinkmann, B.G.7
Kassmann, C.M.8
Tzvetanova, I.D.9
Mobius, W.10
Diaz, F.11
Meijer, D.12
Suter, U.13
Hamprecht, B.14
Sereda, M.W.15
Moraes, C.T.16
Frahm, J.17
Goebbels, S.18
Nave, K.A.19
-
204
-
-
34247611481
-
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment
-
S.W. Scheff, D.A. Price, F.A. Schmitt, S.T. DeKosky, and E.J. Mufson Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment Neurology 68 2007 1501 1508
-
(2007)
Neurology
, vol.68
, pp. 1501-1508
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
DeKosky, S.T.4
Mufson, E.J.5
-
205
-
-
0035503511
-
Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice
-
H. Li, S.H. Li, Z.X. Yu, P. Shelbourne, and X.J. Li Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice J. Neurosci. 21 2001 8473 8481
-
(2001)
J. Neurosci.
, vol.21
, pp. 8473-8481
-
-
Li, H.1
Li, S.H.2
Yu, Z.X.3
Shelbourne, P.4
Li, X.J.5
-
206
-
-
77952926102
-
Clinical progression in Parkinson disease and the neurobiology of axons
-
H.C. Cheng, C.M. Ulane, and R.E. Burke Clinical progression in Parkinson disease and the neurobiology of axons Ann. Neurol. 67 2010 715 725
-
(2010)
Ann. Neurol.
, vol.67
, pp. 715-725
-
-
Cheng, H.C.1
Ulane, C.M.2
Burke, R.E.3
-
207
-
-
84863188413
-
Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease
-
Y. Chu, G.A. Morfini, L.B. Langhamer, Y. He, S.T. Brady, and J.H. Kordower Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease Brain 135 2012 2058 2073
-
(2012)
Brain
, vol.135
, pp. 2058-2073
-
-
Chu, Y.1
Morfini, G.A.2
Langhamer, L.B.3
He, Y.4
Brady, S.T.5
Kordower, J.H.6
-
208
-
-
84908079648
-
Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons
-
A. Berthet, E.B. Margolis, J. Zhang, I. Hsieh, J. Zhang, T.S. Hnasko, J. Ahmad, R.H. Edwards, H. Sesaki, E.J. Huang, and K. Nakamura Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons J. Neurosci. 34 2014 14304 14317
-
(2014)
J. Neurosci.
, vol.34
, pp. 14304-14317
-
-
Berthet, A.1
Margolis, E.B.2
Zhang, J.3
Hsieh, I.4
Zhang, J.5
Hnasko, T.S.6
Ahmad, J.7
Edwards, R.H.8
Sesaki, H.9
Huang, E.J.10
Nakamura, K.11
-
209
-
-
79957467314
-
Ageing as a primary risk factor for Parkinson's disease: Evidence from studies of non-human primates
-
T.J. Collier, N.M. Kanaan, and J.H. Kordower Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates Nat. Rev. Neurosci. 12 2011 359 366
-
(2011)
Nat. Rev. Neurosci.
, vol.12
, pp. 359-366
-
-
Collier, T.J.1
Kanaan, N.M.2
Kordower, J.H.3
-
210
-
-
84878864199
-
The hallmarks of aging
-
C. Lopez-Otin, M.A. Blasco, L. Partridge, M. Serrano, and G. Kroemer The hallmarks of aging Cell 153 2013 1194 1217
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
211
-
-
62349116477
-
The mitochondrial theory of aging: Insight from transgenic and knockout mouse models
-
Y.C. Jang, and H. Van Remmen The mitochondrial theory of aging: insight from transgenic and knockout mouse models Exp. Gerontol. 44 2009 256 260
-
(2009)
Exp. Gerontol.
, vol.44
, pp. 256-260
-
-
Jang, Y.C.1
Van Remmen, H.2
-
212
-
-
84874591240
-
The role of mitochondria in aging
-
A. Bratic, and N.G. Larsson The role of mitochondria in aging J. Clin. Invest. 123 2013 951 957
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 951-957
-
-
Bratic, A.1
Larsson, N.G.2
-
216
-
-
83455181308
-
Synaptic mitochondria in synaptic transmission and organization of vesicle pools in health and disease
-
M. Vos, E. Lauwers, and P. Verstreken Synaptic mitochondria in synaptic transmission and organization of vesicle pools in health and disease Front. Synaptic Neurosci. 2 2010 139
-
(2010)
Front. Synaptic Neurosci.
, vol.2
, pp. 139
-
-
Vos, M.1
Lauwers, E.2
Verstreken, P.3
-
217
-
-
78649962844
-
Brain fuel metabolism, aging, and Alzheimer's disease
-
S. Cunnane, S. Nugent, M. Roy, A. Courchesne-Loyer, E. Croteau, S. Tremblay, A. Castellano, F. Pifferi, C. Bocti, N. Paquet, H. Begdouri, M.h. Bentourkia, E. Turcotte, M. Allard, P. Barberger-Gateau, T. Fulop, and S.I. Rapoport Brain fuel metabolism, aging, and Alzheimer's disease Nutrition 27 2011 3 20
-
(2011)
Nutrition
, vol.27
, pp. 3-20
-
-
Cunnane, S.1
Nugent, S.2
Roy, M.3
Courchesne-Loyer, A.4
Croteau, E.5
Tremblay, S.6
Castellano, A.7
Pifferi, F.8
Bocti, C.9
Paquet, N.10
Begdouri, H.11
Bentourkia, M.H.12
Turcotte, E.13
Allard, M.14
Barberger-Gateau, P.15
Fulop, T.16
Rapoport, S.I.17
-
218
-
-
84922485882
-
Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: A randomized clinical trial
-
Writing Group for the NINDS Exploratory Trials in Parkinson Disease (NET-PD) Investigators K. Kieburtz, B.C. Tilley, J.J. Elm, D. Babcock, R. Hauser, G.W. Ross, A.H. Augustine, E.U. Augustine, M.J. Aminoff, I.G. Bodis-Wollner, J. Boyd, F. Cambi, K. Chou, C.W. Christine, M. Cines, N. Dahodwala, L. Derwent, R.B. Dewey Jr., K. Hawthorne, D.J. Houghton, C. Kamp, M. Leehey, M.F. Lew, G.S. Liang, S.T. Luo, Z. Mari, J.C. Morgan, S. Parashos, A. Perez, H. Petrovitch, S. Rajan, S. Reichwein, J.T. Roth, J.S. Schneider, K.M. Shannon, D.K. Simon, T. Simuni, C. Singer, L. Sudarsky, C.M. Tanner, C.C. Umeh, K. Williams, and A.M. Wills Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial JAMA 313 2015 584 593
-
(2015)
JAMA
, vol.313
, pp. 584-593
-
-
Kieburtz, K.1
Tilley, B.C.2
Elm, J.J.3
Babcock, D.4
Hauser, R.5
Ross, G.W.6
Augustine, A.H.7
Augustine, E.U.8
Aminoff, M.J.9
Bodis-Wollner, I.G.10
Boyd, J.11
Cambi, F.12
Chou, K.13
Christine, C.W.14
Cines, M.15
Dahodwala, N.16
Derwent, L.17
Dewey, R.B.18
Hawthorne, K.19
Houghton, D.J.20
Kamp, C.21
Leehey, M.22
Lew, M.F.23
Liang, G.S.24
Luo, S.T.25
Mari, Z.26
Morgan, J.C.27
Parashos, S.28
Perez, A.29
Petrovitch, H.30
Rajan, S.31
Reichwein, S.32
Roth, J.T.33
Schneider, J.S.34
Shannon, K.M.35
Simon, D.K.36
Simuni, T.37
Singer, C.38
Sudarsky, L.39
Tanner, C.M.40
Umeh, C.C.41
Williams, K.42
Wills, A.M.43
more..
-
219
-
-
84900479240
-
A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: No evidence of benefit
-
M.F. Beal, D. Oakes, I. Shoulson, C. Henchcliffe, W.R. Galpern, R. Haas, J.L. Juncos, J.G. Nutt, T.S. Voss, B. Ravina, C.M. Shults, K. Helles, V. Snively, M.F. Lew, B. Griebner, A. Watts, S. Gao, E. Pourcher, L. Bond, K. Kompoliti, P. Agarwal, C. Sia, M. Jog, L. Cole, M. Sultana, R. Kurlan, I. Richard, C. Deeley, C.H. Waters, A. Figueroa, A. Arkun, M. Brodsky, W.G. Ondo, C.B. Hunter, J. Jimenez-Shahed, A. Palao, J.M. Miyasaki, J. So, J. Tetrud, L. Reys, K. Smith, C. Singer, A. Blenke, D.S. Russell, C. Cotto, J.H. Friedman, M. Lannon, L. Zhang, E. Drasby, R. Kumar, T. Subramanian, D.S. Ford, D.A. Grimes, D. Cote, J. Conway, A.D. Siderowf, M.L. Evatt, B. Sommerfeld, A.N. Lieberman, M.S. Okun, R.L. Rodriguez, S. Merritt, C.L. Swartz, W.R. Martin, P. King, N. Stover, S. Guthrie, R.L. Watts, A. Ahmed, H.H. Fernandez, A. Winters, Z. Mari, T.M. Dawson, B. Dunlop, A.S. Feigin, B. Shannon, M.J. Nirenberg, M. Ogg, S.A. Ellias, C.A. Thomas, K. Frei, I. Bodis-Wollner, S. Glazman, T. Mayer, R.A. Hauser, R. Pahwa, A. Langhammer, R. Ranawaya, L. Derwent, K.D. Sethi, B. Farrow, R. Prakash, I. Litvan, A. Robinson, A. Sahay, M. Gartner, V.K. Hinson, S. Markind, M. Pelikan, J.S. Perlmutter, and et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit JAMA Neurol. 71 2014 543 552
-
(2014)
JAMA Neurol.
, vol.71
, pp. 543-552
-
-
Beal, M.F.1
Oakes, D.2
Shoulson, I.3
Henchcliffe, C.4
Galpern, W.R.5
Haas, R.6
Juncos, J.L.7
Nutt, J.G.8
Voss, T.S.9
Ravina, B.10
Shults, C.M.11
Helles, K.12
Snively, V.13
Lew, M.F.14
Griebner, B.15
Watts, A.16
Gao, S.17
Pourcher, E.18
Bond, L.19
Kompoliti, K.20
Agarwal, P.21
Sia, C.22
Jog, M.23
Cole, L.24
Sultana, M.25
Kurlan, R.26
Richard, I.27
Deeley, C.28
Waters, C.H.29
Figueroa, A.30
Arkun, A.31
Brodsky, M.32
Ondo, W.G.33
Hunter, C.B.34
Jimenez-Shahed, J.35
Palao, A.36
Miyasaki, J.M.37
So, J.38
Tetrud, J.39
Reys, L.40
Smith, K.41
Singer, C.42
Blenke, A.43
Russell, D.S.44
Cotto, C.45
Friedman, J.H.46
Lannon, M.47
Zhang, L.48
Drasby, E.49
Kumar, R.50
Subramanian, T.51
Ford, D.S.52
Grimes, D.A.53
Cote, D.54
Conway, J.55
Siderowf, A.D.56
Evatt, M.L.57
Sommerfeld, B.58
Lieberman, A.N.59
Okun, M.S.60
Rodriguez, R.L.61
Merritt, S.62
Swartz, C.L.63
Martin, W.R.64
King, P.65
Stover, N.66
Guthrie, S.67
Watts, R.L.68
Ahmed, A.69
Fernandez, H.H.70
Winters, A.71
Mari, Z.72
Dawson, T.M.73
Dunlop, B.74
Feigin, A.S.75
Shannon, B.76
Nirenberg, M.J.77
Ogg, M.78
Ellias, S.A.79
Thomas, C.A.80
Frei, K.81
Bodis-Wollner, I.82
Glazman, S.83
Mayer, T.84
Hauser, R.A.85
Pahwa, R.86
Langhammer, A.87
Ranawaya, R.88
Derwent, L.89
Sethi, K.D.90
Farrow, B.91
Prakash, R.92
Litvan, I.93
Robinson, A.94
Sahay, A.95
Gartner, M.96
Hinson, V.K.97
Markind, S.98
Pelikan, M.99
more..
-
220
-
-
84867896682
-
Guanidinoacetate methyltransferase deficiency: First steps to newborn screening for a treatable neurometabolic disease
-
S. Mercimek-Mahmutoglu, G. Sinclair, S.J. van Dooren, W. Kanhai, P. Ashcraft, O.J. Michel, J. Nelson, O.T. Betsalel, L. Sweetman, C. Jakobs, and G.S. Salomons Guanidinoacetate methyltransferase deficiency: first steps to newborn screening for a treatable neurometabolic disease Mol. Genet. Metab. 107 2012 433 437
-
(2012)
Mol. Genet. Metab.
, vol.107
, pp. 433-437
-
-
Mercimek-Mahmutoglu, S.1
Sinclair, G.2
Van Dooren, S.J.3
Kanhai, W.4
Ashcraft, P.5
Michel, O.J.6
Nelson, J.7
Betsalel, O.T.8
Sweetman, L.9
Jakobs, C.10
Salomons, G.S.11
-
221
-
-
84891830726
-
GAMT deficiency: 20 years of a treatable inborn error of metabolism
-
O. Braissant GAMT deficiency: 20 years of a treatable inborn error of metabolism Mol. Genet. Metab. 111 2014 1 3
-
(2014)
Mol. Genet. Metab.
, vol.111
, pp. 1-3
-
-
Braissant, O.1
-
222
-
-
0034730011
-
Quinone-responsive multiple respiratory-chain dysfunction due to widespread coenzyme Q10 deficiency
-
A. Rotig, E.L. Appelkvist, V. Geromel, D. Chretien, N. Kadhom, P. Edery, M. Lebideau, G. Dallner, A. Munnich, L. Ernster, and P. Rustin Quinone-responsive multiple respiratory-chain dysfunction due to widespread coenzyme Q10 deficiency Lancet 356 2000 391 395
-
(2000)
Lancet
, vol.356
, pp. 391-395
-
-
Rotig, A.1
Appelkvist, E.L.2
Geromel, V.3
Chretien, D.4
Kadhom, N.5
Edery, P.6
Lebideau, M.7
Dallner, G.8
Munnich, A.9
Ernster, L.10
Rustin, P.11
-
223
-
-
65549087610
-
A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: A potentially treatable form of mitochondrial disease
-
A.J. Duncan, M. Bitner-Glindzicz, B. Meunier, H. Costello, I.P. Hargreaves, L.C. Lopez, M. Hirano, C.M. Quinzii, M.I. Sadowski, J. Hardy, A. Singleton, P.T. Clayton, and S. Rahman A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: a potentially treatable form of mitochondrial disease Am. J. Hum. Genet. 84 2009 558 566
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 558-566
-
-
Duncan, A.J.1
Bitner-Glindzicz, M.2
Meunier, B.3
Costello, H.4
Hargreaves, I.P.5
Lopez, L.C.6
Hirano, M.7
Quinzii, C.M.8
Sadowski, M.I.9
Hardy, J.10
Singleton, A.11
Clayton, P.T.12
Rahman, S.13
-
224
-
-
84907212899
-
Does ketogenic diet improve cognitive function in patients with GLUT1-DS? A 6- to 17-month follow-up study
-
A. Ramm-Pettersen, K.E. Stabell, K.O. Nakken, and K.K. Selmer Does ketogenic diet improve cognitive function in patients with GLUT1-DS? A 6- to 17-month follow-up study Epilepsy Behav. 39 2014 111 115
-
(2014)
Epilepsy Behav.
, vol.39
, pp. 111-115
-
-
Ramm-Pettersen, A.1
Stabell, K.E.2
Nakken, K.O.3
Selmer, K.K.4
-
225
-
-
84940959315
-
GLUT1 deficiency syndrome and ketogenic diet therapies: Missing rare but treatable diseases?
-
J. Klepper GLUT1 deficiency syndrome and ketogenic diet therapies: missing rare but treatable diseases? Dev. Med. Child Neurol. 2015
-
(2015)
Dev. Med. Child Neurol.
-
-
Klepper, J.1
-
226
-
-
84874322054
-
Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila
-
S. Song, S. Jang, J. Park, S. Bang, S. Choi, K.Y. Kwon, X. Zhuang, E. Kim, and J. Chung Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila J. Biol. Chem. 288 2013 5660 5672
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 5660-5672
-
-
Song, S.1
Jang, S.2
Park, J.3
Bang, S.4
Choi, S.5
Kwon, K.Y.6
Zhuang, X.7
Kim, E.8
Chung, J.9
-
227
-
-
84882754147
-
A neo-substrate that amplifies catalytic activity of Parkinson's-disease-related kinase PINK1
-
N.T. Hertz, A. Berthet, M.L. Sos, K.S. Thorn, A.L. Burlingame, K. Nakamura, and K.M. Shokat A neo-substrate that amplifies catalytic activity of Parkinson's-disease-related kinase PINK1 Cell 154 2013 737 747
-
(2013)
Cell
, vol.154
, pp. 737-747
-
-
Hertz, N.T.1
Berthet, A.2
Sos, M.L.3
Thorn, K.S.4
Burlingame, A.L.5
Nakamura, K.6
Shokat, K.M.7
-
228
-
-
84875910694
-
Sulfhydration mediates neuroprotective actions of parkin
-
M.S. Vandiver, B.D. Paul, R. Xu, S. Karuppagounder, F. Rao, A.M. Snowman, H.S. Ko, Y.I. Lee, V.L. Dawson, T.M. Dawson, N. Sen, and S.H. Snyder Sulfhydration mediates neuroprotective actions of parkin Nat. Commun. 4 2013 1626
-
(2013)
Nat. Commun.
, vol.4
, pp. 1626
-
-
Vandiver, M.S.1
Paul, B.D.2
Xu, R.3
Karuppagounder, S.4
Rao, F.5
Snowman, A.M.6
Ko, H.S.7
Lee, Y.I.8
Dawson, V.L.9
Dawson, T.M.10
Sen, N.11
Snyder, S.H.12
-
229
-
-
84887625913
-
Phase II safety, tolerability, and dose selection study of isradipine as a potential disease-modifying intervention in early Parkinson's disease (STEADY-PD)
-
G. Parkinson Study Phase II safety, tolerability, and dose selection study of isradipine as a potential disease-modifying intervention in early Parkinson's disease (STEADY-PD) Mov. Disord. 28 2013 1823 1831
-
(2013)
Mov. Disord.
, vol.28
, pp. 1823-1831
-
-
Parkinson Study, G.1
|