Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

Journal of Neurochemistry

Volumn 121, Issue 5, 2012, Pages 830-839

  Wang, Xinglong ^a,b   Petrie, Timothy G ^a   Liu, Yingchao ^c   Liu, Jun ^d   Fujioka, Hisashi ^b   Zhu, Xiongwei ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SHANDONG UNIVERSITY   (China)

^d SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

DJ 1; Drp1; mitochondrial elongation; mitochondrial fragmentation; mitochondrial fusion; Parkinson disease

Indexed keywords

DYNAMIN I;

ARTICLE; CAUSAL ATTRIBUTION; CELL SIZE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOCHONDRION; MUTATION; NERVE CELL; NERVE CELL NECROSIS; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

BLOTTING, WESTERN; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GTP PHOSPHOHYDROLASES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; ONCOGENE PROTEINS; PARKINSON DISEASE; TRANSFECTION;

EID: 84860539187     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07734.x     Document Type: Article

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