메뉴 건너뛰기




Volumn 16, Issue 2, 2014, Pages 217-230

Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease

Author keywords

1 Methyl 4 phenyl 1 2,3,6 tetrahydropyridine (MPTP); Astaxanthin; Oxidative stress; Parkinson's disease; PTEN induced kinase 1 (PINK1); Signaling pathways

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALPHA TOCOPHEROL; ASTAXANTHIN; ENVIRONMENTAL CHEMICAL; MITOCHONDRIAL DNA; PARKIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PTEN INDUCED KINASE 1; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TOXIN; UNCLASSIFIED DRUG; ABELSON KINASE; DROSOPHILA PROTEIN; GLUTAMATE RECEPTOR; HEAVY METAL; METALLOPROTEINASE; MITOCHONDRIAL PROTEIN; NEUROPROTECTIVE AGENT; NEUROTOXIN; PARL PROTEIN, HUMAN; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE; XANTHOPHYLL;

EID: 84901321275     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-014-8294-x     Document Type: Article
Times cited : (178)

References (138)
  • 1
    • 79251543343 scopus 로고    scopus 로고
    • Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice
    • 1:CAS:528:DC%2BC3MXhtFWnsLw%3D 3020954 21249202
    • Akundi, R. S., et al. (2011). Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice. PLoS ONE, 6(1), e16038.
    • (2011) PLoS ONE , vol.6 , Issue.1 , pp. 16038
    • Akundi, R.S.1
  • 2
    • 0030878073 scopus 로고    scopus 로고
    • Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
    • 1:CAS:528:DyaK2sXls1Chtbs%3D 9282943
    • Alam, Z. I., et al. (1997). Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. Journal of Neurochemistry, 69(3), 1196-1203.
    • (1997) Journal of Neurochemistry , vol.69 , Issue.3 , pp. 1196-1203
    • Alam, Z.I.1
  • 3
    • 35748981177 scopus 로고    scopus 로고
    • HtrA2 and Parkinson's disease: Think PINK?
    • 1:CAS:528:DC%2BD2sXht1Cgu7fK 17975547
    • Alnemri, E. S. (2007). HtrA2 and Parkinson's disease: Think PINK? Nature Cell Biology, 9(11), 1227-1229.
    • (2007) Nature Cell Biology , vol.9 , Issue.11 , pp. 1227-1229
    • Alnemri, E.S.1
  • 4
    • 3142514196 scopus 로고    scopus 로고
    • Oxidative stress in neurodegeneration: Cause or consequence?
    • 15298006
    • Andersen, J. K. (2004). Oxidative stress in neurodegeneration: Cause or consequence? Nature Medicine, 10(Suppl), S18-S25.
    • (2004) Nature Medicine , vol.10 , Issue.SUPPL.
    • Andersen, J.K.1
  • 5
    • 84872195238 scopus 로고    scopus 로고
    • Mitochondria drive autophagy pathology via microtubule disassembly: A new hypothesis for Parkinson disease
    • 1:CAS:528:DC%2BC3sXjtlKgsLo%3D 3542213 23075854
    • Arduino, D. M., Esteves, A. R., & Cardoso, S. M. (2013). Mitochondria drive autophagy pathology via microtubule disassembly: A new hypothesis for Parkinson disease. Autophagy, 9(1), 112-114.
    • (2013) Autophagy , vol.9 , Issue.1 , pp. 112-114
    • Arduino, D.M.1    Esteves, A.R.2    Cardoso, S.M.3
  • 6
    • 1642308134 scopus 로고    scopus 로고
    • Neurodegenerative diseases and oxidative stress
    • 1:CAS:528:DC%2BD2cXit12nsL4%3D 15031734
    • Barnham, K. J., Masters, C. L., & Bush, A. I. (2004). Neurodegenerative diseases and oxidative stress. Nature Reviews Drug Discovery, 3(3), 205-214.
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.3 , pp. 205-214
    • Barnham, K.J.1    Masters, C.L.2    Bush, A.I.3
  • 7
    • 0038051345 scopus 로고    scopus 로고
    • Mitochondria, oxidative damage, and inflammation in Parkinson's disease
    • 1:CAS:528:DC%2BD3sXmtVCku78%3D 12846981
    • Beal, M. F. (2003). Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Annals of the New York Academy of Sciences, 991, 120-131.
    • (2003) Annals of the New York Academy of Sciences , vol.991 , pp. 120-131
    • Beal, M.F.1
  • 8
    • 0034993599 scopus 로고    scopus 로고
    • Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
    • 1:CAS:528:DC%2BD3MXkt1Kitbo%3D 11403877
    • Blum, D., et al. (2001). Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease. Progress in Neurobiology, 65(2), 135-172.
    • (2001) Progress in Neurobiology , vol.65 , Issue.2 , pp. 135-172
    • Blum, D.1
  • 9
    • 0034007822 scopus 로고    scopus 로고
    • Pathoanatomy of Parkinson's disease
    • Braak, H., & Braak, E. (2000). Pathoanatomy of Parkinson's disease. Journal of Neurology, 247(Suppl 2), II3-II10.
    • (2000) Journal of Neurology , vol.247 , Issue.SUPPL. 2
    • Braak, H.1    Braak, E.2
  • 10
    • 67649756320 scopus 로고    scopus 로고
    • Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease
    • 19303005
    • Bueler, H. (2009). Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease. Experimental Neurology, 218(2), 235-246.
    • (2009) Experimental Neurology , vol.218 , Issue.2 , pp. 235-246
    • Bueler, H.1
  • 12
    • 24744435115 scopus 로고    scopus 로고
    • Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
    • 1:CAS:528:DC%2BD2MXpslelur8%3D 16127437
    • Camps, M., et al. (2005). Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nature Medicine, 11(9), 936-943.
    • (2005) Nature Medicine , vol.11 , Issue.9 , pp. 936-943
    • Camps, M.1
  • 13
    • 0035853788 scopus 로고    scopus 로고
    • The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress
    • 1:CAS:528:DC%2BD3MXjtFymtbs%3D 11278261
    • Cao, C., et al. (2001). The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress. Journal of Biological Chemistry, 276(15), 11465-11468.
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.15 , pp. 11465-11468
    • Cao, C.1
  • 14
    • 69749118947 scopus 로고    scopus 로고
    • Antioxidative and anti-inflammatory neuroprotective effects of astaxanthin and canthaxanthin in nerve growth factor differentiated PC12 cells
    • 1:CAS:528:DC%2BD1MXht1ajtbzJ 19895474
    • Chan, K. C., Mong, M. C., & Yin, M. C. (2009). Antioxidative and anti-inflammatory neuroprotective effects of astaxanthin and canthaxanthin in nerve growth factor differentiated PC12 cells. Journal of Food Science, 74(7), H225-H231.
    • (2009) Journal of Food Science , vol.74 , Issue.7
    • Chan, K.C.1    Mong, M.C.2    Yin, M.C.3
  • 15
    • 84875121203 scopus 로고    scopus 로고
    • Parkinson's disease: A complex interplay of mitochondrial DNA alterations and oxidative stress
    • 1:CAS:528:DC%2BC3sXitFKisLc%3D 3587993 23348931
    • Ciccone, S., et al. (2013). Parkinson's disease: A complex interplay of mitochondrial DNA alterations and oxidative stress. International Journal of Molecular Sciences, 14(2), 2388-2409.
    • (2013) International Journal of Molecular Sciences , vol.14 , Issue.2 , pp. 2388-2409
    • Ciccone, S.1
  • 16
    • 9644259048 scopus 로고    scopus 로고
    • Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death
    • 1:CAS:528:DC%2BD2cXhtVWjs7nF 15371414
    • Cilenti, L., et al. (2004). Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death. Journal of Biological Chemistry, 279(48), 50295-50301.
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.48 , pp. 50295-50301
    • Cilenti, L.1
  • 17
    • 79951967246 scopus 로고    scopus 로고
    • HTRA proteases: Regulated proteolysis in protein quality control
    • 1:CAS:528:DC%2BC3MXhvFKltbk%3D 21326199
    • Clausen, T., et al. (2011). HTRA proteases: Regulated proteolysis in protein quality control. Nature Reviews Molecular Cell Biology, 12, 152-162.
    • (2011) Nature Reviews Molecular Cell Biology , vol.12 , pp. 152-162
    • Clausen, T.1
  • 18
    • 84864475028 scopus 로고    scopus 로고
    • Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells
    • 1:CAS:528:DC%2BC38XmtlKjsL4%3D 3399985 22549737
    • Constance, J., Despres, S., Nishida, A., & Lim, C. (2012). Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells. Pharmaceutical Research, 29(8), 2317-2328.
    • (2012) Pharmaceutical Research , vol.29 , Issue.8 , pp. 2317-2328
    • Constance, J.1    Despres, S.2    Nishida, A.3    Lim, C.4
  • 19
    • 77953890085 scopus 로고    scopus 로고
    • Parkinson's disease: Insights from pathways
    • 1:CAS:528:DC%2BC3cXmsVSrtb8%3D 2875048 20421364
    • Cookson, M. R., & Bandmann, O. (2010). Parkinson's disease: Insights from pathways. Human Molecular Genetics, 19(R1), R21-R27.
    • (2010) Human Molecular Genetics , vol.19 , Issue.R1
    • Cookson, M.R.1    Bandmann, O.2
  • 20
    • 80054787664 scopus 로고    scopus 로고
    • What genetics tells us about the causes and mechanisms of Parkinson's disease
    • 1:CAS:528:DC%2BC3MXhsVOjsbrN 22013209
    • Corti, O., Lesage, S., & Brice, A. (2011). What genetics tells us about the causes and mechanisms of Parkinson's disease. Physiological Reviews, 91(4), 1161-1218.
    • (2011) Physiological Reviews , vol.91 , Issue.4 , pp. 1161-1218
    • Corti, O.1    Lesage, S.2    Brice, A.3
  • 21
    • 84878533362 scopus 로고    scopus 로고
    • Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease
    • doi: 10.1038/cddis.2012.205
    • Costa, A. C., Loh, S. H. Y., & Martins, M. (2013). Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease. Cell Death Disease, 4, e467; doi: 10.1038/cddis.2012.205.
    • (2013) Cell Death Disease , vol.4
    • Costa, A.C.1    Loh, S.H.Y.2    Martins, M.3
  • 22
    • 84860474062 scopus 로고    scopus 로고
    • Genetically engineered mouse models of Parkinson's disease
    • 1:CAS:528:DC%2BC38XmsVGlu7Y%3D 3244549 21839151
    • Crabtree, D. M., & Zhang, J. (2012). Genetically engineered mouse models of Parkinson's disease. Brain Research Bulletin, 88(1), 13-32.
    • (2012) Brain Research Bulletin , vol.88 , Issue.1 , pp. 13-32
    • Crabtree, D.M.1    Zhang, J.2
  • 23
    • 80052091852 scopus 로고    scopus 로고
    • Parkinson disease: Insights in clinical, genetic and pathological features of monogenic disease subtypes
    • 1:CAS:528:DC%2BC3MXhtFShu77I 21810464
    • Crosiers, D., et al. (2011). Parkinson disease: Insights in clinical, genetic and pathological features of monogenic disease subtypes. Journal of Chemical Neuroanatomy, 42(2), 131-141.
    • (2011) Journal of Chemical Neuroanatomy , vol.42 , Issue.2 , pp. 131-141
    • Crosiers, D.1
  • 24
    • 4444237686 scopus 로고    scopus 로고
    • Role of oxidative stress in neurodegeneration: Recent developments in assay methods for oxidative stress and nutraceutical antioxidants
    • 1:CAS:528:DC%2BD2cXnsFSqtLs%3D 15363603
    • Cui, K., et al. (2004). Role of oxidative stress in neurodegeneration: Recent developments in assay methods for oxidative stress and nutraceutical antioxidants. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 28(5), 771-799.
    • (2004) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.28 , Issue.5 , pp. 771-799
    • Cui, K.1
  • 25
    • 0038475847 scopus 로고    scopus 로고
    • Protein carbonylation in human diseases
    • 1:CAS:528:DC%2BD3sXjt1Cnt74%3D 12727143
    • Dalle-Donne, I., et al. (2003). Protein carbonylation in human diseases. Trends in Molecular Medicine, 9(4), 169-176.
    • (2003) Trends in Molecular Medicine , vol.9 , Issue.4 , pp. 169-176
    • Dalle-Donne, I.1
  • 26
    • 77953666105 scopus 로고    scopus 로고
    • Genetic animal models of Parkinson's disease
    • 1:CAS:528:DC%2BC3cXnvFaksb4%3D 2917798 20547124
    • Dawson, T. M., Ko, H. S., & Dawson, V. L. (2010). Genetic animal models of Parkinson's disease. Neuron, 66(5), 646-661.
    • (2010) Neuron , vol.66 , Issue.5 , pp. 646-661
    • Dawson, T.M.1    Ko, H.S.2    Dawson, V.L.3
  • 27
    • 76149104800 scopus 로고    scopus 로고
    • PINK1 function in health and disease
    • 1:CAS:528:DC%2BD1MXhtVWrurfP 3378127 20049715
    • Deas, E., Plun-Favreau, H., & Wood, N. W. (2009). PINK1 function in health and disease. EMBO Mol Med, 1(3), 152-165.
    • (2009) EMBO Mol Med , vol.1 , Issue.3 , pp. 152-165
    • Deas, E.1    Plun-Favreau, H.2    Wood, N.W.3
  • 28
    • 79551574736 scopus 로고    scopus 로고
    • PINK1 cleavage at position A103 by the mitochondrial protease PARL
    • 1:CAS:528:DC%2BC3MXhsFylsLw%3D 3033179 21138942
    • Deas, E., et al. (2011). PINK1 cleavage at position A103 by the mitochondrial protease PARL. Human Molecular Genetics, 20(5), 867-879.
    • (2011) Human Molecular Genetics , vol.20 , Issue.5 , pp. 867-879
    • Deas, E.1
  • 29
    • 0036751978 scopus 로고    scopus 로고
    • A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes
    • 1:CAS:528:DC%2BD38XotVCitbg%3D 12392777
    • Esposito, E., et al. (2002). A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes. Neurobiology of Aging, 23(5), 719-735.
    • (2002) Neurobiology of Aging , vol.23 , Issue.5 , pp. 719-735
    • Esposito, E.1
  • 30
    • 76949097385 scopus 로고    scopus 로고
    • Gene therapy in Parkinson's disease: Rationale and current status
    • 1:CAS:528:DC%2BC3cXlslCis70%3D 2886503 20155994
    • Feng, L. R., & Maguire-Zeiss, K. A. (2010). Gene therapy in Parkinson's disease: Rationale and current status. CNS Drugs, 24(3), 177-192.
    • (2010) CNS Drugs , vol.24 , Issue.3 , pp. 177-192
    • Feng, L.R.1    Maguire-Zeiss, K.A.2
  • 31
    • 0036174010 scopus 로고    scopus 로고
    • Alpha-Synuclein is phosphorylated in synucleinopathy lesions
    • 1:CAS:528:DC%2BD38XhsVKnur4%3D 11813001
    • Fujiwara, H., et al. (2002). Alpha-Synuclein is phosphorylated in synucleinopathy lesions. Nature Cell Biology, 4(2), 160-164.
    • (2002) Nature Cell Biology , vol.4 , Issue.2 , pp. 160-164
    • Fujiwara, H.1
  • 32
    • 50549085408 scopus 로고    scopus 로고
    • Neuroinflammation and oxidation/nitration of alpha-synuclein linked to dopaminergic neurodegeneration
    • 1:CAS:528:DC%2BD1cXpt12muro%3D 2702093 18650345
    • Gao, H. M., et al. (2008). Neuroinflammation and oxidation/nitration of alpha-synuclein linked to dopaminergic neurodegeneration. Journal of Neuroscience, 28(30), 7687-7698.
    • (2008) Journal of Neuroscience , vol.28 , Issue.30 , pp. 7687-7698
    • Gao, H.M.1
  • 33
    • 0034986361 scopus 로고    scopus 로고
    • Oxidative stress induced-neurodegenerative diseases: The need for antioxidants that penetrate the blood brain barrier
    • 1:CAS:528:DC%2BD3MXkt1Kis70%3D 11406187
    • Gilgun-Sherki, Y., Melamed, E., & Offen, D. (2001). Oxidative stress induced-neurodegenerative diseases: The need for antioxidants that penetrate the blood brain barrier. Neuropharmacology, 40(8), 959-975.
    • (2001) Neuropharmacology , vol.40 , Issue.8 , pp. 959-975
    • Gilgun-Sherki, Y.1    Melamed, E.2    Offen, D.3
  • 34
    • 84860489734 scopus 로고    scopus 로고
    • Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease
    • 1:CAS:528:DC%2BC38XntlWgtr4%3D 3341364 22563483
    • Gollamudi, S., et al. (2012). Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease. PLoS ONE, 7(5), e36191.
    • (2012) PLoS ONE , vol.7 , Issue.5 , pp. 36191
    • Gollamudi, S.1
  • 35
    • 84863644570 scopus 로고    scopus 로고
    • Oxidative stress, DNA damage, and c-Abl signaling: At the crossroad in neurodegenerative diseases?
    • 3385657 22761618
    • Gonfloni, S., et al. (2012). Oxidative stress, DNA damage, and c-Abl signaling: At the crossroad in neurodegenerative diseases? International Journal of Cell Biology, 2012, 683097.
    • (2012) International Journal of Cell Biology , vol.2012 , pp. 683097
    • Gonfloni, S.1
  • 36
    • 28044450643 scopus 로고    scopus 로고
    • The basal ganglia: Learning new tricks and loving it
    • 1:CAS:528:DC%2BD2MXht1Ggu7fP 16271465
    • Graybiel, A. M. (2005). The basal ganglia: Learning new tricks and loving it. Current Opinion in Neurobiology, 15(6), 638-644.
    • (2005) Current Opinion in Neurobiology , vol.15 , Issue.6 , pp. 638-644
    • Graybiel, A.M.1
  • 37
    • 84859428688 scopus 로고    scopus 로고
    • Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
    • 1:CAS:528:DC%2BC38Xit12gurk%3D 3321149 22354088
    • Greene, A. W., et al. (2012). Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. EMBO Reports, 13(4), 378-385.
    • (2012) EMBO Reports , vol.13 , Issue.4 , pp. 378-385
    • Greene, A.W.1
  • 38
    • 84872474938 scopus 로고    scopus 로고
    • Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease
    • 1:CAS:528:DC%2BC3sXit1Wrsrs%3D 23001711
    • Gu, G. J., et al. (2013). Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease. Journal of Alzheimer's Disease, 33(3), 699-713.
    • (2013) Journal of Alzheimer's Disease , vol.33 , Issue.3 , pp. 699-713
    • Gu, G.J.1
  • 39
    • 78649866553 scopus 로고    scopus 로고
    • Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
    • 1:CAS:528:DC%2BC3cXhtl2rtb7F 21068725
    • Guzman, J. N., et al. (2010). Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature, 468(7324), 696-700.
    • (2010) Nature , vol.468 , Issue.7324 , pp. 696-700
    • Guzman, J.N.1
  • 40
    • 18144406539 scopus 로고    scopus 로고
    • Oxidative stress and inflammation in Parkinson's disease: Is there a causal link?
    • 1:CAS:528:DC%2BD2MXjslKjtbo%3D 15869932
    • Hald, A., & Lotharius, J. (2005). Oxidative stress and inflammation in Parkinson's disease: Is there a causal link? Experimental Neurology, 193(2), 279-290.
    • (2005) Experimental Neurology , vol.193 , Issue.2 , pp. 279-290
    • Hald, A.1    Lotharius, J.2
  • 41
    • 77950296916 scopus 로고    scopus 로고
    • Bioconjugates of curcumin display improved protection against glutathione depletion mediated oxidative stress in a dopaminergic neuronal cell line: Implications for Parkinson's disease
    • 1:CAS:528:DC%2BC3cXksVejtrs%3D
    • Harish, G., et al. (2010). Bioconjugates of curcumin display improved protection against glutathione depletion mediated oxidative stress in a dopaminergic neuronal cell line: Implications for Parkinson's disease. Bioorganic & Medicinal Chemistry, 18(7), 2631-2638.
    • (2010) Bioorganic & Medicinal Chemistry , vol.18 , Issue.7 , pp. 2631-2638
    • Harish, G.1
  • 42
    • 79953156438 scopus 로고    scopus 로고
    • Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance
    • Heeman, B., et al. (2011). Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance. Journal of Cell Science, 24(Pt 7), 1115-1125.
    • (2011) Journal of Cell Science , vol.24 , Issue.PART 7 , pp. 1115-1125
    • Heeman, B.1
  • 43
    • 55849122639 scopus 로고    scopus 로고
    • Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
    • 1:CAS:528:DC%2BD1cXhtlWktbnM 18978800
    • Henchcliffe, C., & Beal, M. F. (2008). Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nature Clinical Practice Neurology, 4(11), 600-609.
    • (2008) Nature Clinical Practice Neurology , vol.4 , Issue.11 , pp. 600-609
    • Henchcliffe, C.1    Beal, M.F.2
  • 44
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: A target for neuroprotection?
    • 1:CAS:528:DC%2BD1MXks1Sis70%3D 19296921
    • Hirsch, E. C., & Hunot, S. (2009). Neuroinflammation in Parkinson's disease: A target for neuroprotection? Lancet Neurology, 8(4), 382-397.
    • (2009) Lancet Neurology , vol.8 , Issue.4 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 45
    • 77957020116 scopus 로고    scopus 로고
    • Gene-environment interactions in Parkinson's disease: The importance of animal modeling
    • 1:STN:280:DC%2BC3cfjs1WisQ%3D%3D 3085510 20811350
    • Horowitz, M. P., & Greenamyre, J. T. (2010). Gene-environment interactions in Parkinson's disease: The importance of animal modeling. Clinical Pharmacology and Therapeutics, 88(4), 467-474.
    • (2010) Clinical Pharmacology and Therapeutics , vol.88 , Issue.4 , pp. 467-474
    • Horowitz, M.P.1    Greenamyre, J.T.2
  • 46
    • 0032152948 scopus 로고    scopus 로고
    • Oxidative stress and Parkinson's disease
    • 1:STN:280:DyaK1M7hvFKgug%3D%3D
    • Ilic, T., et al. (1998). Oxidative stress and Parkinson's disease. Vojnosanitetski Pregled., 55(5), 463-468.
    • (1998) Vojnosanitetski Pregled. , vol.55 , Issue.5 , pp. 463-468
    • Ilic, T.1
  • 47
    • 78650881155 scopus 로고    scopus 로고
    • Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: Implications for Parkinson's disease
    • 1:CAS:528:DC%2BC3MXls1yhug%3D%3D 3039694 21209200
    • Imam, S. Z., et al. (2011). Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: Implications for Parkinson's disease. Journal of Neuroscience, 31(1), 157-163.
    • (2011) Journal of Neuroscience , vol.31 , Issue.1 , pp. 157-163
    • Imam, S.Z.1
  • 48
    • 75549087261 scopus 로고    scopus 로고
    • Emerging roles of Wnts in the adult nervous system
    • 1:CAS:528:DC%2BD1MXhsFKjsr3O 20010950
    • Inestrosa, N. C., & Arenas, E. (2010). Emerging roles of Wnts in the adult nervous system. Nature Reviews Neuroscience, 11(2), 77-86.
    • (2010) Nature Reviews Neuroscience , vol.11 , Issue.2 , pp. 77-86
    • Inestrosa, N.C.1    Arenas, E.2
  • 49
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • 1:CAS:528:DC%2BD3sXjtFGitLs%3D 12666096
    • Jenner, P. (2003). Oxidative stress in Parkinson's disease. Annals of Neurology, 53(Suppl 3), S26-S36.
    • (2003) Annals of Neurology , vol.53 , Issue.SUPPL. 3
    • Jenner, P.1
  • 50
    • 78149456920 scopus 로고    scopus 로고
    • Inflammatory responses are not sufficient to cause delayed neuronal death in ATP-induced acute brain injury
    • Jeong, H. K., et al. (2010). Inflammatory responses are not sufficient to cause delayed neuronal death in ATP-induced acute brain injury. PLoS ONE, 10, e13756.
    • (2010) PLoS ONE , vol.10 , pp. 13756
    • Jeong, H.K.1
  • 51
    • 35048867410 scopus 로고    scopus 로고
    • Resident microglia die and infiltrated neutrophils and monocytes become major inflammatory cells in lipopolysaccharide-injected brain
    • 17823975
    • Ji, K. A., et al. (2007). Resident microglia die and infiltrated neutrophils and monocytes become major inflammatory cells in lipopolysaccharide-injected brain. Glia, 55(15), 1577-1588.
    • (2007) Glia , vol.55 , Issue.15 , pp. 1577-1588
    • Ji, K.A.1
  • 52
    • 75849152052 scopus 로고    scopus 로고
    • Glutamate receptors as therapeutic targets for Parkinson's disease
    • 1:CAS:528:DC%2BD1MXhsFGqt7fM
    • Johnson, K. A., Conn, P. J., & Niswender, C. M. (2009). Glutamate receptors as therapeutic targets for Parkinson's disease. CNS & Neurological Disorders: Drug Targets, 8(6), 475-491.
    • (2009) CNS & Neurological Disorders: Drug Targets , vol.8 , Issue.6 , pp. 475-491
    • Johnson, K.A.1    Conn, P.J.2    Niswender, C.M.3
  • 53
    • 0142246441 scopus 로고    scopus 로고
    • Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice
    • 1:CAS:528:DC%2BD3sXotV2hsr8%3D 14534547
    • Jones, J. M., et al. (2003). Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice. Nature, 425(6959), 721-727.
    • (2003) Nature , vol.425 , Issue.6959 , pp. 721-727
    • Jones, J.M.1
  • 54
    • 1342305460 scopus 로고    scopus 로고
    • Proteolytic activation of proapoptotic kinase PKCdelta is regulated by overexpression of Bcl-2: Implications for oxidative stress and environmental factors in Parkinson's disease
    • 1:CAS:528:DC%2BD2cXisFeqs7Y%3D 15033812
    • Kanthasamy, A. G., et al. (2003). Proteolytic activation of proapoptotic kinase PKCdelta is regulated by overexpression of Bcl-2: Implications for oxidative stress and environmental factors in Parkinson's disease. Annals of the New York Academy of Sciences, 1010, 683-686.
    • (2003) Annals of the New York Academy of Sciences , vol.1010 , pp. 683-686
    • Kanthasamy, A.G.1
  • 55
    • 80053643245 scopus 로고    scopus 로고
    • Downregulation of Wnt/beta-catenin signaling causes degeneration of hippocampal neurons in vivo
    • Kim, H. et al. (2011). Downregulation of Wnt/beta-catenin signaling causes degeneration of hippocampal neurons in vivo. Neurobiology of Aging, 32(12), 2316 e1-e15.
    • (2011) Neurobiology of Aging , vol.32 , Issue.12
    • Kim, H.1
  • 56
    • 84883638818 scopus 로고    scopus 로고
    • PINK1 deficiency enhances inflammatory cytokine release from acutely prepared brain slices
    • 3620457 23585721
    • Kim, J., et al. (2013). PINK1 deficiency enhances inflammatory cytokine release from acutely prepared brain slices. Experimental Neurobiology, 22(1), 38-44.
    • (2013) Experimental Neurobiology , vol.22 , Issue.1 , pp. 38-44
    • Kim, J.1
  • 57
    • 78049275348 scopus 로고    scopus 로고
    • Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function
    • 1:CAS:528:DC%2BC3cXht1ajsbfP
    • Ko, H. S., et al. (2010). Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function. Proceedings of National Academic Science USA, 107(38), 16691-16696.
    • (2010) Proceedings of National Academic Science USA , vol.107 , Issue.38 , pp. 16691-16696
    • Ko, H.S.1
  • 59
    • 4143096025 scopus 로고    scopus 로고
    • Dexamethasone protects against dopaminergic neurons damage in a mouse model of Parkinson's disease
    • 1:CAS:528:DC%2BD2cXmslehtbs%3D 15313429
    • Kurkowska-Jastrzebska, I., et al. (2004). Dexamethasone protects against dopaminergic neurons damage in a mouse model of Parkinson's disease. International Immunopharmacology, 4(10-11), 1307-1318.
    • (2004) International Immunopharmacology , vol.4 , Issue.10-11 , pp. 1307-1318
    • Kurkowska-Jastrzebska, I.1
  • 60
    • 69449086642 scopus 로고    scopus 로고
    • Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis
    • 1:CAS:528:DC%2BD1MXhtVaksrrJ 2764260 19701198
    • Kuwabara, T., et al. (2009). Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nature Neuroscience, 12(9), 1097-1105.
    • (2009) Nature Neuroscience , vol.12 , Issue.9 , pp. 1097-1105
    • Kuwabara, T.1
  • 61
    • 0023931333 scopus 로고
    • Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study
    • 1:CAS:528:DyaL1cXhs1GlsL8%3D 3364159
    • Kuzuhara, S., et al. (1988). Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study. Acta Neuropathologica, 75(4), 345-353.
    • (1988) Acta Neuropathologica , vol.75 , Issue.4 , pp. 345-353
    • Kuzuhara, S.1
  • 62
    • 77954323088 scopus 로고    scopus 로고
    • Glia as a turning point in the therapeutic strategy of Parkinson's disease
    • L'Episcopo, F., et al. (2010). Glia as a turning point in the therapeutic strategy of Parkinson's disease. CNS & Neurological Disorders: Drug Targets, 9(3), 349-372.
    • (2010) CNS & Neurological Disorders: Drug Targets , vol.9 , Issue.3 , pp. 349-372
    • L'Episcopo, F.1
  • 63
    • 78650621911 scopus 로고    scopus 로고
    • Reactive astrocytes and Wnt/beta-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
    • L'Episcopo, F., et al. (2011a). Reactive astrocytes and Wnt/beta-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine model of Parkinson's disease. Neurobiology of Diseases, 41(2), 508-527.
    • (2011) Neurobiology of Diseases , vol.41 , Issue.2 , pp. 508-527
    • L'Episcopo, F.1
  • 64
    • 79960123794 scopus 로고    scopus 로고
    • A Wnt1 regulated Frizzled-1/beta-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection
    • 3162575 21752258
    • L'Episcopo, F., et al. (2011b). A Wnt1 regulated Frizzled-1/beta-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection. Molecular Neurodegeneration, 6, 49.
    • (2011) Molecular Neurodegeneration , vol.6 , pp. 49
    • L'Episcopo, F.1
  • 65
    • 84856981228 scopus 로고    scopus 로고
    • Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/beta-catenin signaling pathways: Functional consequences for neuroprotection and repair
    • 3556384 22323720
    • L'Episcopo, F., et al. (2012). Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/beta-catenin signaling pathways: Functional consequences for neuroprotection and repair. Journal of Neuroscience, 32(6), 2062-2085.
    • (2012) Journal of Neuroscience , vol.32 , Issue.6 , pp. 2062-2085
    • L'Episcopo, F.1
  • 66
    • 0021263249 scopus 로고
    • 1-Methyl-4-phenylpyridinium ion (MPP +): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra
    • 1:CAS:528:DyaL2cXlt1Cgt7c%3D 6332288
    • Langston, J. W., et al. (1984). 1-Methyl-4-phenylpyridinium ion (MPP +): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra. Neuroscience Letters, 48(1), 87-92.
    • (1984) Neuroscience Letters , vol.48 , Issue.1 , pp. 87-92
    • Langston, J.W.1
  • 67
    • 84858693790 scopus 로고    scopus 로고
    • Role of Mendelian genes in "sporadic" Parkinson's disease
    • Lesage, S., & Brice, A. (2012). Role of Mendelian genes in "sporadic" Parkinson's disease. Parkinsonism & Related Disorders, 18(Suppl 1), S66-S70.
    • (2012) Parkinsonism & Related Disorders , vol.18 , Issue.SUPPL. 1
    • Lesage, S.1    Brice, A.2
  • 68
    • 0036263973 scopus 로고    scopus 로고
    • Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi
    • 1:CAS:528:DC%2BD38XjvFOms70%3D
    • Li, W., et al. (2002). Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi. Natural Structural Biology, 9(6), 436-441.
    • (2002) Natural Structural Biology , vol.9 , Issue.6 , pp. 436-441
    • Li, W.1
  • 69
    • 77957840160 scopus 로고    scopus 로고
    • Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases
    • 1:CAS:528:DC%2BC3cXht1Kms77L 20467442
    • Li, B., et al. (2010a). Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases. Cell Death and Differentiation, 17, 1773-1784.
    • (2010) Cell Death and Differentiation , vol.17 , pp. 1773-1784
    • Li, B.1
  • 70
    • 77956124557 scopus 로고    scopus 로고
    • Tetrahydroxystilbene glucoside attenuates MPP + -induced apoptosis in PC12 cells by inhibiting ROS generation and modulating JNK activation
    • 1:CAS:528:DC%2BC3cXhtV2itb3M 20643188
    • Li, X., et al. (2010b). Tetrahydroxystilbene glucoside attenuates MPP + -induced apoptosis in PC12 cells by inhibiting ROS generation and modulating JNK activation. Neuroscience Letters, 483(1), 1-5.
    • (2010) Neuroscience Letters , vol.483 , Issue.1 , pp. 1-5
    • Li, X.1
  • 71
    • 58549103079 scopus 로고    scopus 로고
    • Astaxanthin inhibits reactive oxygen species-mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism
    • 1:CAS:528:DC%2BD1MXhtVens7k%3D 19101523
    • Liu, X., et al. (2009). Astaxanthin inhibits reactive oxygen species-mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism. Brain Research, 1254, 18-27.
    • (2009) Brain Research , vol.1254 , pp. 18-27
    • Liu, X.1
  • 72
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • 1:CAS:528:DC%2BD2cXhtVejsr7I 15473860
    • Logan, C. Y., & Nusse, R. (2004). The Wnt signaling pathway in development and disease. Annual Review of Cell and Developmental Biology, 20, 781-810.
    • (2004) Annual Review of Cell and Developmental Biology , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 73
    • 0036884733 scopus 로고    scopus 로고
    • Pathogenesis of Parkinson's disease: Dopamine, vesicles and alpha-synuclein
    • 1:CAS:528:DC%2BD38XptFKntbk%3D 12461550
    • Lotharius, J., & Brundin, P. (2002). Pathogenesis of Parkinson's disease: Dopamine, vesicles and alpha-synuclein. Nature Reviews Neuroscience, 3(12), 932-942.
    • (2002) Nature Reviews Neuroscience , vol.3 , Issue.12 , pp. 932-942
    • Lotharius, J.1    Brundin, P.2
  • 74
    • 34548425994 scopus 로고    scopus 로고
    • The phosphorylation of tyrosine 332 is necessary for the caspase 3-dependent cleavage of PKCdelta and the regulation of cell apoptosis
    • 1:CAS:528:DC%2BD2sXovFyltr8%3D 17658731
    • Lu, W., et al. (2007). The phosphorylation of tyrosine 332 is necessary for the caspase 3-dependent cleavage of PKCdelta and the regulation of cell apoptosis. Cellular Signalling, 19(10), 2165-2173.
    • (2007) Cellular Signalling , vol.19 , Issue.10 , pp. 2165-2173
    • Lu, W.1
  • 75
    • 25144468525 scopus 로고    scopus 로고
    • To be or not to be (inflamed) - Is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?
    • 1:CAS:528:DC%2BD2MXhtVarsbjF 16126283
    • Marchetti, B., & Abbracchio, M. P. (2005). To be or not to be (inflamed) - is that the question in anti-inflammatory drug therapy of neurodegenerative disorders? Trends in Pharmacological Sciences, 26(10), 517-525.
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.10 , pp. 517-525
    • Marchetti, B.1    Abbracchio, M.P.2
  • 76
    • 61349156769 scopus 로고    scopus 로고
    • Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux
    • 1:CAS:528:DC%2BD1MXjsFWgsbs%3D 3902824 19166511
    • Marongiu, R., et al. (2009). Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux. Journal of Neurochemistry, 108(6), 1561-1574.
    • (2009) Journal of Neurochemistry , vol.108 , Issue.6 , pp. 1561-1574
    • Marongiu, R.1
  • 77
    • 7644230386 scopus 로고    scopus 로고
    • Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice
    • 1:CAS:528:DC%2BD2cXpslOntbo%3D 525490 15509788
    • Martins, L. M., et al. (2004). Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. Molecular and Cellular Biology, 24(22), 9848-9862.
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.22 , pp. 9848-9862
    • Martins, L.M.1
  • 78
    • 84858022944 scopus 로고    scopus 로고
    • Microtubule affinity-regulating kinase 2 (MARK2) turns on phosphatase and tensin homolog (PTEN)-induced kinase 1 (PINK1) at Thr-313, a mutation site in Parkinson disease: Effects on mitochondrial transport
    • 1:CAS:528:DC%2BC38XjsFCrsro%3D 3318756 22238344
    • Matenia, D., et al. (2012). Microtubule affinity-regulating kinase 2 (MARK2) turns on phosphatase and tensin homolog (PTEN)-induced kinase 1 (PINK1) at Thr-313, a mutation site in Parkinson disease: Effects on mitochondrial transport. Journal of Biological Chemistry, 287(11), 8174-8186.
    • (2012) Journal of Biological Chemistry , vol.287 , Issue.11 , pp. 8174-8186
    • Matenia, D.1
  • 80
    • 78650642949 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain
    • 1:CAS:528:DC%2BC3cXhsFSltbzN 21098227
    • Medina, E. A., Morris, I. R., & Berton, M. T. (2010). Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain. The Journal of Immunology, 185(12), 7562-7572.
    • (2010) The Journal of Immunology , vol.185 , Issue.12 , pp. 7562-7572
    • Medina, E.A.1    Morris, I.R.2    Berton, M.T.3
  • 81
    • 79955667485 scopus 로고    scopus 로고
    • The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
    • 1:CAS:528:DC%2BC3MXmsFCmt7Y%3D 21426348
    • Meissner, C., et al. (2011). The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. Journal of Neurochemistry, 117(5), 856-867.
    • (2011) Journal of Neurochemistry , vol.117 , Issue.5 , pp. 856-867
    • Meissner, C.1
  • 82
    • 84861386201 scopus 로고    scopus 로고
    • Spatial and temporal correlation in progressive degeneration of neurons and astrocytes in contusion-induced spinal cord injury
    • 3418552 22632146
    • Min, K. J., et al. (2012). Spatial and temporal correlation in progressive degeneration of neurons and astrocytes in contusion-induced spinal cord injury. Journal of Neuroinflammation, 9, 100.
    • (2012) Journal of Neuroinflammation , vol.9 , pp. 100
    • Min, K.J.1
  • 83
    • 65249180086 scopus 로고    scopus 로고
    • Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons
    • 1:CAS:528:DC%2BD1MXlvFSrtrs%3D 2677560 19409267
    • Mosharov, E. V., et al. (2009). Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. Neuron, 62(2), 218-229.
    • (2009) Neuron , vol.62 , Issue.2 , pp. 218-229
    • Mosharov, E.V.1
  • 84
    • 79551553483 scopus 로고    scopus 로고
    • Wnt signaling regulates neuronal differentiation of cortical intermediate progenitors
    • 1:CAS:528:DC%2BC3MXhvFGkuro%3D 3040956 21289176
    • Munji, R. N., et al. (2011). Wnt signaling regulates neuronal differentiation of cortical intermediate progenitors. Journal of Neuroscience, 31(5), 1676-1687.
    • (2011) Journal of Neuroscience , vol.31 , Issue.5 , pp. 1676-1687
    • Munji, R.N.1
  • 85
    • 79953185407 scopus 로고    scopus 로고
    • A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1. Activation of Akt via mTORC2
    • 1:CAS:528:DC%2BC3MXisVyqs78%3D 3044975 21177249
    • Murata, H., et al. (2011). A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1. Activation of Akt via mTORC2. Journal of Biological Chemistry, 286(9), 7182-7189.
    • (2011) Journal of Biological Chemistry , vol.286 , Issue.9 , pp. 7182-7189
    • Murata, H.1
  • 86
    • 79961207643 scopus 로고    scopus 로고
    • Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains
    • 1:CAS:528:DC%2BC3MXksFWntbg%3D 21484266
    • Mythri, R. B., et al. (2011). Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains. Neurochemical Research, 36(8), 1452-1463.
    • (2011) Neurochemical Research , vol.36 , Issue.8 , pp. 1452-1463
    • Mythri, R.B.1
  • 88
    • 0034011558 scopus 로고    scopus 로고
    • Antioxidant activities of astaxanthin and related carotenoids
    • 1:CAS:528:DC%2BD3cXhvVyrsro%3D
    • Naguib, Y. M. (2000). Antioxidant activities of astaxanthin and related carotenoids. Journal of Agriculture and Food Chemistry, 48(4), 1150-1154.
    • (2000) Journal of Agriculture and Food Chemistry , vol.48 , Issue.4 , pp. 1150-1154
    • Naguib, Y.M.1
  • 89
    • 77549085875 scopus 로고    scopus 로고
    • 2+-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategies
    • 1:CAS:528:DC%2BC3cXjtVSms7Y%3D 2875138 20060165
    • 2+-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategies. Cell Calcium, 47(2), 190-197.
    • (2010) Cell Calcium , vol.47 , Issue.2 , pp. 190-197
    • Nakamura, T.1    Lipton, S.A.2
  • 90
    • 80051781073 scopus 로고    scopus 로고
    • Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases
    • 1:CAS:528:DC%2BC3MXhtVWnt73E 3178424 21597461
    • Nakamura, T., & Lipton, S. A. (2011). Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases. Cell Death and Differentiation, 18(9), 1478-1486.
    • (2011) Cell Death and Differentiation , vol.18 , Issue.9 , pp. 1478-1486
    • Nakamura, T.1    Lipton, S.A.2
  • 91
    • 75749156257 scopus 로고    scopus 로고
    • PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
    • 2811155 20126261
    • Narendra, D. P., et al. (2010). PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biology, 8(1), e1000298.
    • (2010) PLoS Biology , vol.8 , Issue.1 , pp. 1000298
    • Narendra, D.P.1
  • 92
    • 79951978630 scopus 로고    scopus 로고
    • Mitochondrial ion circuits
    • 1:CAS:528:DC%2BC3cXpvFKktrY%3D 20533898
    • Nicholls, D. G. (2010). Mitochondrial ion circuits. Essays in Biochemistry, 47, 25-35.
    • (2010) Essays in Biochemistry , vol.47 , pp. 25-35
    • Nicholls, D.G.1
  • 93
    • 84863430453 scopus 로고    scopus 로고
    • Mitophagy: A complex mechanism of mitochondrial removal
    • 1:CAS:528:DC%2BC38XpsFKmu7c%3D
    • Novak, I. (2012). Mitophagy: A complex mechanism of mitochondrial removal. Antioxidants & Redox Signaling, 17(5), 794-802.
    • (2012) Antioxidants & Redox Signaling , vol.17 , Issue.5 , pp. 794-802
    • Novak, I.1
  • 94
    • 84866072587 scopus 로고    scopus 로고
    • PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
    • 3432468 22910362
    • Okatsu, K., et al. (2012). PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria. Nature Communications, 3, 1016.
    • (2012) Nature Communications , vol.3 , pp. 1016
    • Okatsu, K.1
  • 95
    • 33748345432 scopus 로고    scopus 로고
    • Ubiquitin-proteasome system and Parkinson's disease
    • 16972273
    • Olanow, C. W., & McNaught, K. S. (2006). Ubiquitin-proteasome system and Parkinson's disease. Movement Disorders, 21(11), 1806-1823.
    • (2006) Movement Disorders , vol.21 , Issue.11 , pp. 1806-1823
    • Olanow, C.W.1    McNaught, K.S.2
  • 96
    • 0030724621 scopus 로고    scopus 로고
    • Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease
    • 1:STN:280:DyaK1c7gs12ksw%3D%3D 9444566
    • Pearce, R. K., et al. (1997). Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease. Journal of Neural Transmission, 104(6-7), 661-677.
    • (1997) Journal of Neural Transmission , vol.104 , Issue.6-7 , pp. 661-677
    • Pearce, R.K.1
  • 97
    • 35748935851 scopus 로고    scopus 로고
    • The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
    • 1:CAS:528:DC%2BD2sXht1Cgu7fN 17906618
    • Plun-Favreau, H., et al. (2007). The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nature Cell Biology, 9(11), 1243-1252.
    • (2007) Nature Cell Biology , vol.9 , Issue.11 , pp. 1243-1252
    • Plun-Favreau, H.1
  • 98
    • 57649194934 scopus 로고    scopus 로고
    • What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?
    • 1:CAS:528:DC%2BD1MXhsVaqtLc%3D 19076428
    • Plun-Favreau, H., et al. (2008). What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease? Annals of the New York Academy of Sciences, 1147, 30-36.
    • (2008) Annals of the New York Academy of Sciences , vol.1147 , pp. 30-36
    • Plun-Favreau, H.1
  • 99
    • 31644448700 scopus 로고    scopus 로고
    • A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo
    • 1:CAS:528:DC%2BD28XhtFGgtbY%3D 16339193
    • Prakash, N., et al. (2006). A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development, 133(1), 89-98.
    • (2006) Development , vol.133 , Issue.1 , pp. 89-98
    • Prakash, N.1
  • 100
    • 34547127902 scopus 로고    scopus 로고
    • PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
    • 1892574 17579517
    • Pridgeon, J. W., et al. (2007). PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biology, 5(7), e172.
    • (2007) PLoS Biology , vol.5 , Issue.7 , pp. 172
    • Pridgeon, J.W.1
  • 101
    • 33846453291 scopus 로고    scopus 로고
    • Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons
    • 1:CAS:528:DC%2BD2sXhtFSkurc%3D 17234596
    • Puopolo, M., Raviola, E., & Bean, B. P. (2007). Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons. Journal of Neuroscience, 27(3), 645-656.
    • (2007) Journal of Neuroscience , vol.27 , Issue.3 , pp. 645-656
    • Puopolo, M.1    Raviola, E.2    Bean, B.P.3
  • 102
    • 0032579949 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia
    • 1:CAS:528:DyaK1cXisVGiu7k%3D 9579682
    • Pyo, H., et al. (1998). Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia. NeuroReport, 9(5), 871-874.
    • (1998) NeuroReport , vol.9 , Issue.5 , pp. 871-874
    • Pyo, H.1
  • 103
    • 42549153340 scopus 로고    scopus 로고
    • The PKCdelta-Abl complex communicates ER stress to the mitochondria - An essential step in subsequent apoptosis
    • 1:CAS:528:DC%2BD1cXlvFektb0%3D 18285444
    • Qi, X., & Mochly-Rosen, D. (2008). The PKCdelta-Abl complex communicates ER stress to the mitochondria - an essential step in subsequent apoptosis. Journal of Cell Science, 121(6), 804-813.
    • (2008) Journal of Cell Science , vol.121 , Issue.6 , pp. 804-813
    • Qi, X.1    Mochly-Rosen, D.2
  • 104
    • 80054090021 scopus 로고    scopus 로고
    • View point: Etiology in Parkinson's disease. Dual hit or spreading intoxication
    • 21600591
    • Reichmann, H. (2011). View point: Etiology in Parkinson's disease. Dual hit or spreading intoxication. Journal of the Neurological Sciences, 310(1-2), 9-11.
    • (2011) Journal of the Neurological Sciences , vol.310 , Issue.1-2 , pp. 9-11
    • Reichmann, H.1
  • 105
    • 77956405386 scopus 로고    scopus 로고
    • Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
    • 1:CAS:528:DC%2BC3cXhtFGju7bM 20643181
    • Roberts, R. A., et al. (2010). Toxicological and pathophysiological roles of reactive oxygen and nitrogen species. Toxicology, 276(2), 85-94.
    • (2010) Toxicology , vol.276 , Issue.2 , pp. 85-94
    • Roberts, R.A.1
  • 107
    • 0034730753 scopus 로고    scopus 로고
    • Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B
    • 1:CAS:528:DC%2BD3cXnt1ahtb0%3D 10893407
    • Ryu, J., et al. (2000). Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B. Journal of Biological Chemistry, 275(39), 29955-29959.
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.39 , pp. 29955-29959
    • Ryu, J.1
  • 108
    • 0032527641 scopus 로고    scopus 로고
    • (E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease
    • 1:CAS:528:DyaK1cXktl2ru74%3D
    • Selley, M. L. (1998). (E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease. Free Radical Biology & Medicine, 25(2), 169-174.
    • (1998) Free Radical Biology & Medicine , vol.25 , Issue.2 , pp. 169-174
    • Selley, M.L.1
  • 109
    • 77949478474 scopus 로고    scopus 로고
    • Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kB signaling
    • 1:CAS:528:DC%2BD1MXhs1WisLfP 2796895 19880420
    • Sha, D., Chin, L. S., & Li, L. (2010). Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kB signaling. Human Molecular Genetics, 19(2), 352-363.
    • (2010) Human Molecular Genetics , vol.19 , Issue.2 , pp. 352-363
    • Sha, D.1    Chin, L.S.2    Li, L.3
  • 110
    • 0033933048 scopus 로고    scopus 로고
    • Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
    • 1:STN:280:DC%2BD3czptF2nsw%3D%3D 10888878
    • Shimura, H., et al. (2000). Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nature Genetics, 25(3), 302-305.
    • (2000) Nature Genetics , vol.25 , Issue.3 , pp. 302-305
    • Shimura, H.1
  • 111
    • 79551647053 scopus 로고    scopus 로고
    • Wnt signaling pathway overcomes the disruption of neuronal differentiation of neural progenitor cells induced by oligomeric amyloid beta-peptide
    • 1:CAS:528:DC%2BC3MXisFKlu7c%3D 21138436
    • Shruster, A., et al. (2011). Wnt signaling pathway overcomes the disruption of neuronal differentiation of neural progenitor cells induced by oligomeric amyloid beta-peptide. Journal of Neurochemistry, 116(4), 522-529.
    • (2011) Journal of Neurochemistry , vol.116 , Issue.4 , pp. 522-529
    • Shruster, A.1
  • 113
    • 84874322054 scopus 로고    scopus 로고
    • Characterization of phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1) mutations associated with Parkinson's disease in mammalian cells and Drosophila
    • 1:CAS:528:DC%2BC3sXjtVGgsbo%3D 3581423 23303188
    • Song, S., et al. (2013). Characterization of phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1) mutations associated with Parkinson's disease in mammalian cells and Drosophila. Journal of Biological Chemistry, 288(8), 5660-5672.
    • (2013) Journal of Biological Chemistry , vol.288 , Issue.8 , pp. 5660-5672
    • Song, S.1
  • 114
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis
    • 1:CAS:528:DC%2BD2MXktFOju7w%3D 15771584
    • Sospedra, M., & Martin, R. (2005). Immunology of multiple sclerosis. Annual Review of Immunology, 23, 683-747.
    • (2005) Annual Review of Immunology , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 115
    • 3042539146 scopus 로고    scopus 로고
    • Parkinson's prevalence estimated by a state registry
    • 15022187
    • Strickland, D., & Bertoni, J. M. (2004). Parkinson's prevalence estimated by a state registry. Movement Disorders, 19(3), 318-323.
    • (2004) Movement Disorders , vol.19 , Issue.3 , pp. 318-323
    • Strickland, D.1    Bertoni, J.M.2
  • 116
    • 0034677930 scopus 로고    scopus 로고
    • Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress
    • 1:CAS:528:DC%2BD3cXitVymurk%3D 10713049
    • Sun, X., et al. (2000). Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress. Journal of Biological Chemistry, 275(11), 7470-7473.
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.11 , pp. 7470-7473
    • Sun, X.1
  • 117
    • 84857547632 scopus 로고    scopus 로고
    • Autosomal dominant Parkinson's disease
    • Sundal, C., et al. (2012). Autosomal dominant Parkinson's disease. Parkinsonism & Related Disorders, 18(Suppl 1), S7-S10.
    • (2012) Parkinsonism & Related Disorders , vol.18 , Issue.SUPPL. 1
    • Sundal, C.1
  • 118
    • 81255149611 scopus 로고    scopus 로고
    • The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease
    • 1:CAS:528:DC%2BC3MXhsV2rsLfK 3244353 21884755
    • Surmeier, D. J., et al. (2011). The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease. Neuroscience, 198, 221-231.
    • (2011) Neuroscience , vol.198 , pp. 221-231
    • Surmeier, D.J.1
  • 119
    • 67650718212 scopus 로고    scopus 로고
    • Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin
    • 1:CAS:528:DC%2BD1MXoslOiurs%3D 2711053 19282869
    • Tain, L. S., et al. (2009). Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin. Cell Death and Differentiation, 16(8), 1118-1125.
    • (2009) Cell Death and Differentiation , vol.16 , Issue.8 , pp. 1118-1125
    • Tain, L.S.1
  • 120
    • 48349136909 scopus 로고    scopus 로고
    • Progress in Parkinson's disease-where do we stand?
    • 18582530
    • Toulouse, A., & Sullivan, A. M. (2008). Progress in Parkinson's disease-where do we stand? Progress in Neurobiology, 85(4), 376-392.
    • (2008) Progress in Neurobiology , vol.85 , Issue.4 , pp. 376-392
    • Toulouse, A.1    Sullivan, A.M.2
  • 121
    • 2442668926 scopus 로고    scopus 로고
    • Hereditary early-onset Parkinson's disease caused by mutations in PINK1
    • 1:CAS:528:DC%2BD2cXktVyit7k%3D 15087508
    • Valente, E. M., et al. (2004). Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science, 304(5674), 1158-1160.
    • (2004) Science , vol.304 , Issue.5674 , pp. 1158-1160
    • Valente, E.M.1
  • 122
    • 84864928966 scopus 로고    scopus 로고
    • Oxidative stress in genetic mouse models of Parkinson's disease
    • 3399377 22829959
    • Varcin, M., et al. (2012). Oxidative stress in genetic mouse models of Parkinson's disease. Oxidative Medicine and Cellular Longevity, 2012, 624925.
    • (2012) Oxidative Medicine and Cellular Longevity , vol.2012 , pp. 624925
    • Varcin, M.1
  • 123
    • 79960137032 scopus 로고    scopus 로고
    • Altered oxidative stress levels in Indian Parkinson's disease patients with PARK2 mutations
    • 1:CAS:528:DC%2BC3MXotlOitbg%3D 21584286
    • Vinish, M., Anand, A., & Prabhakar, S. (2011). Altered oxidative stress levels in Indian Parkinson's disease patients with PARK2 mutations. Acta Biochimica Polonica, 58(2), 165-169.
    • (2011) Acta Biochimica Polonica , vol.58 , Issue.2 , pp. 165-169
    • Vinish, M.1    Anand, A.2    Prabhakar, S.3
  • 124
    • 34648819365 scopus 로고    scopus 로고
    • The Lewy body in Parkinson's disease: Molecules implicated in the formation and degradation of alpha-synuclein aggregates
    • 18018486
    • Wakabayashi, K., et al. (2007). The Lewy body in Parkinson's disease: Molecules implicated in the formation and degradation of alpha-synuclein aggregates. Neuropathology, 27(5), 494-506.
    • (2007) Neuropathology , vol.27 , Issue.5 , pp. 494-506
    • Wakabayashi, K.1
  • 125
    • 39449117350 scopus 로고    scopus 로고
    • Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation
    • 1:CAS:528:DC%2BD1cXitVKns78%3D 17968353
    • Wexler, E. M., Geschwind, D. H., & Palmer, T. D. (2008). Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation. Molecular Psychiatry, 13(3), 285-292.
    • (2008) Molecular Psychiatry , vol.13 , Issue.3 , pp. 285-292
    • Wexler, E.M.1    Geschwind, D.H.2    Palmer, T.D.3
  • 126
    • 34247366072 scopus 로고    scopus 로고
    • Inflammation as a causative factor in the aetiology of Parkinson's disease
    • 1:CAS:528:DC%2BD2sXkt1Chsr8%3D 2013918 17339843
    • Whitton, P. S. (2007). Inflammation as a causative factor in the aetiology of Parkinson's disease. British Journal of Pharmacology, 150(8), 963-976.
    • (2007) British Journal of Pharmacology , vol.150 , Issue.8 , pp. 963-976
    • Whitton, P.S.1
  • 127
    • 58149397651 scopus 로고    scopus 로고
    • Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
    • 1:CAS:528:DC%2BD1cXhtlyisr3O
    • Whitworth, A. J., et al. (2008). Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin. Disease Models & Mechanisms, 1(2-3), 168-174.
    • (2008) Disease Models & Mechanisms , vol.1 , Issue.2-3 , pp. 168-174
    • Whitworth, A.J.1
  • 128
    • 49349087497 scopus 로고    scopus 로고
    • PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
    • 2413012 18560593
    • Wood-Kaczmar, A., et al. (2008). PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PLoS ONE, 3(6), e2455.
    • (2008) PLoS ONE , vol.3 , Issue.6 , pp. 2455
    • Wood-Kaczmar, A.1
  • 129
    • 68649126582 scopus 로고    scopus 로고
    • Targets for neuroprotection in Parkinson's disease
    • 1:CAS:528:DC%2BD1MXnsFygs7w%3D 2740981 18930814
    • Yacoubian, T. A., & Standaert, D. G. (2009). Targets for neuroprotection in Parkinson's disease. Biochimica et Biophysica Acta, 1792(7), 676-687.
    • (2009) Biochimica et Biophysica Acta , vol.1792 , Issue.7 , pp. 676-687
    • Yacoubian, T.A.1    Standaert, D.G.2
  • 130
    • 84884879594 scopus 로고    scopus 로고
    • Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
    • 1:CAS:528:DC%2BC3sXhtVOqtg%3D%3D
    • Yan, M. H., Wang, X., & Zhu, X. (2013). Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease. Free Radical Biology & Medicine, 62, 90-101.
    • (2013) Free Radical Biology & Medicine , vol.62 , pp. 90-101
    • Yan, M.H.1    Wang, X.2    Zhu, X.3
  • 131
    • 84876961942 scopus 로고    scopus 로고
    • Astaxanthin suppresses MPP+ -induced oxidative damage in PC12 cells through a Sp1/NR1 signaling pathway
    • 1:CAS:528:DC%2BC3sXlvVyitro%3D 3705385 23538867
    • Ye, Q., et al. (2013). Astaxanthin suppresses MPP+ -induced oxidative damage in PC12 cells through a Sp1/NR1 signaling pathway. Marine Drugs, 11(4), 1019-1034.
    • (2013) Marine Drugs , vol.11 , Issue.4 , pp. 1019-1034
    • Ye, Q.1
  • 132
    • 77957152778 scopus 로고    scopus 로고
    • Terminal differentiation of chronic myelogenous leukemia cells is induced by targeting of the MUC1-C oncoprotein
    • 1:CAS:528:DC%2BC3cXhs1akurvK
    • Yin, L., et al. (2010). Terminal differentiation of chronic myelogenous leukemia cells is induced by targeting of the MUC1-C oncoprotein. Cancer Biology & Therapy, 10(5), 483-491.
    • (2010) Cancer Biology & Therapy , vol.10 , Issue.5 , pp. 483-491
    • Yin, L.1
  • 133
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • 1:CAS:528:DC%2BD1MXhtlSjur%2FP 19851315
    • Yu, H., Pardoll, D., & Jove, R. (2009). STATs in cancer inflammation and immunity: A leading role for STAT3. Nature Reviews Cancer, 9(11), 798-809.
    • (2009) Nature Reviews Cancer , vol.9 , Issue.11 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 134
    • 58149375389 scopus 로고    scopus 로고
    • Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo
    • 1:CAS:528:DC%2BD1MXnsF2nug%3D%3D 2718055 19118185
    • Yun, J., et al. (2008). Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo. Journal of Neuroscience, 28(53), 14500-14510.
    • (2008) Journal of Neuroscience , vol.28 , Issue.53 , pp. 14500-14510
    • Yun, J.1
  • 135
    • 3042793602 scopus 로고    scopus 로고
    • The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging
    • 1:CAS:528:DC%2BD2cXlvVahtLY%3D
    • Zecca, L., et al. (2004). The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging. Proceedings of National Academic Science USA, 101(26), 9843-9848.
    • (2004) Proceedings of National Academic Science USA , vol.101 , Issue.26 , pp. 9843-9848
    • Zecca, L.1
  • 136
    • 78650793848 scopus 로고    scopus 로고
    • The Wnt/beta-catenin signaling pathway in the adult neurogenesis
    • 21073552
    • Zhang, L., et al. (2011). The Wnt/beta-catenin signaling pathway in the adult neurogenesis. European Journal of Neuroscience, 33(1), 1-8.
    • (2011) European Journal of Neuroscience , vol.33 , Issue.1 , pp. 1-8
    • Zhang, L.1
  • 137
    • 84878510699 scopus 로고    scopus 로고
    • Human neuromelanin: An endogenous microglial activator for dopaminergic neuron death
    • 1:CAS:528:DC%2BC3sXltVKitbc%3D
    • Zhang, W., et al. (2013). Human neuromelanin: An endogenous microglial activator for dopaminergic neuron death. Frontiers in Bioscience (Elite Edition), 5, 1-11.
    • (2013) Frontiers in Bioscience (Elite Edition) , vol.5 , pp. 1-11
    • Zhang, W.1
  • 138
    • 50149121528 scopus 로고    scopus 로고
    • The kinase domain of mitochondrial PINK1 faces the cytoplasm
    • 1:CAS:528:DC%2BD1cXhtVChu73I
    • Zhou, C., et al. (2008). The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proceedings of National Academic Science USA, 105(33), 12022-12027.
    • (2008) Proceedings of National Academic Science USA , vol.105 , Issue.33 , pp. 12022-12027
    • Zhou, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.